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Tag Content
iUUCD ID IUUC-Ggo-044791
Ensembl Protein ID ENSGGOP00000016403.2
UniProt Accession G3RKX1; G3RKX1_GORGO
Protein Name Histone-lysine N-methyltransferase
Gene Name KMT2B
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGGOG00000016796.2 ENSGGOT00000025977.1 ENSGGOP00000020736.1
ENSGGOG00000016796.2 ENSGGOT00000016867.2 ENSGGOP00000016403.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 4.20e-30 104.1 1000 1053
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++++  wiC+ C ++
   Q: 1000 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRKRrhWICSACVRC 1053
           58********************************.88888877777******876 PP
   
Organism Gorilla gorilla
Protein Sequence
(Fasta)
PRGAGGGGGR GGRGNGAERV RVALRRGGGA TGPGGAEPGE DTALLRLLGL RRGLRRLRRL 60
WAGPRVQRGR GRGRGRGWGP SRGCVPEEES SDGESDEEEF QGFHSDEDVA PSSLRSALRS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ggo-044791|E3,PHD|Gorilla gorilla
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGACTACAT TTCCCGGAGG CCCCCGCGGC TCGCCCCTCT GCGGCCGCGA CGNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ggo-044791|E3,PHD|Gorilla gorilla
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002367 Ailuropoda melanoleuca 94.56 0.00e+00 2172.00
IUUC-Aca-004718 Anolis carolinensis 65.60 0.00e+00 1350.00
IUUC-Ame-011927 Astyanax mexicanus 44.93 0.00e+00 855.00
IUUC-Bta-013578 Bos taurus 92.53 0.00e+00 2078.00
IUUC-Bdi-014882 Brachypodium distachyon 33.33 2.00e-27 117.00
IUUC-Bra-017422 Brassica rapa 33.50 1.00e-27 118.00
IUUC-Cja-019138 Callithrix jacchus 97.65 0.00e+00 2258.00
IUUC-Cfa-020020 Canis familiaris 94.49 0.00e+00 2048.00
IUUC-Cpo-021552 Cavia porcellus 90.90 0.00e+00 2063.00
IUUC-Csa-024216 Chlorocebus sabaeus 98.45 0.00e+00 2238.00
IUUC-Cho-024565 Choloepus hoffmanni 77.83 4.00e-163 569.00
IUUC-Csv-026268 Ciona savignyi 38.91 5.00e-129 456.00
IUUC-Dre-027440 Danio rerio 45.70 0.00e+00 897.00
IUUC-Dno-029583 Dasypus novemcinctus 93.98 0.00e+00 2162.00
IUUC-Dor-030903 Dipodomys ordii 90.22 0.00e+00 1931.00
IUUC-Dme-032023 Drosophila melanogaster 47.56 6.00e-93 337.00
IUUC-Eca-034026 Equus caballus 94.15 0.00e+00 1946.00
IUUC-Eeu-034687 Erinaceus europaeus 92.85 0.00e+00 1070.00
IUUC-Fca-036311 Felis catus 94.41 0.00e+00 2146.00
IUUC-Gmo-039265 Gadus morhua 45.36 0.00e+00 813.00
IUUC-Gac-042202 Gasterosteus aculeatus 47.89 0.00e+00 742.00
IUUC-Hsa-046988 Homo sapiens 99.48 0.00e+00 2233.00
IUUC-Hvu-047762 Hordeum vulgare 36.57 4.00e-20 92.80
IUUC-Itr-048907 Ictidomys tridecemlineatus 94.34 0.00e+00 2231.00
IUUC-Lpe-051476 Leersia perrieri 31.51 4.00e-24 107.00
IUUC-Loc-052252 Lepisosteus oculatus 53.73 0.00e+00 777.00
IUUC-Laf-053703 Loxodonta africana 91.85 0.00e+00 2120.00
IUUC-Mcc-054782 Macaca mulatta 97.10 0.00e+00 2225.00
IUUC-Meu-056046 Macropus eugenii 87.60 0.00e+00 1674.00
IUUC-Mmr-061316 Microcebus murinus 92.60 0.00e+00 2076.00
IUUC-Mdo-062648 Monodelphis domestica 83.39 0.00e+00 1870.00
IUUC-Mmu-063579 Mus musculus 91.84 0.00e+00 2151.00
IUUC-Mac-064935 Musa acuminata 32.02 9.00e-30 125.00
IUUC-Mpu-066710 Mustela putorius furo 94.05 0.00e+00 2128.00
IUUC-Mlu-067559 Myotis lucifugus 93.01 0.00e+00 2120.00
IUUC-Nle-070085 Nomascus leucogenys 99.12 0.00e+00 2061.00
IUUC-Opr-071148 Ochotona princeps 91.97 0.00e+00 2126.00
IUUC-Ont-071626 Oreochromis niloticus 49.02 0.00e+00 782.00
IUUC-Ocu-074475 Oryctolagus cuniculus 93.46 0.00e+00 2029.00
IUUC-Obr-076458 Oryza brachyantha 34.48 4.00e-28 119.00
IUUC-Ogl-077851 Oryza glaberrima 36.26 4.00e-28 119.00
IUUC-Ogu-078706 Oryza glumaepatula 36.26 2.00e-28 120.00
IUUC-Oin-079802 Oryza indica 31.43 3.00e-23 103.00
IUUC-Osa-085421 Oryza sativa 36.26 6.00e-28 119.00
IUUC-Ola-086609 Oryzias latipes 48.27 0.00e+00 750.00
IUUC-Oga-088140 Otolemur garnettii 94.42 0.00e+00 2108.00
IUUC-Oar-089447 Ovis aries 91.84 0.00e+00 1966.00
IUUC-Ptr-090902 Pan troglodytes 99.34 0.00e+00 2236.00
IUUC-Pan-091930 Papio anubis 98.53 0.00e+00 2237.00
IUUC-Ppa-095221 Physcomitrella patens 36.54 9.00e-31 128.00
IUUC-Pfo-096884 Poecilia formosa 45.56 0.00e+00 880.00
IUUC-Pab-098404 Pongo abelii 97.89 0.00e+00 1065.00
IUUC-Pop-099620 Populus trichocarpa 31.65 1.00e-26 115.00
IUUC-Pca-100949 Procavia capensis 89.20 0.00e+00 1120.00
IUUC-Ppe-101920 Prunus persica 33.01 1.00e-27 118.00
IUUC-Pva-102634 Pteropus vampyrus 92.72 0.00e+00 2145.00
IUUC-Rno-105870 Rattus norvegicus 91.91 0.00e+00 2196.00
IUUC-Sit-110552 Setaria italica 34.33 9.00e-29 121.00
IUUC-Sar-113289 Sorex araneus 89.85 0.00e+00 1758.00
IUUC-Ssc-115509 Sus scrofa 93.41 0.00e+00 2132.00
IUUC-Tru-117736 Takifugu rubripes 46.19 0.00e+00 817.00
IUUC-Tca-121624 Theobroma cacao 32.67 1.00e-27 118.00
IUUC-Tae-124647 Triticum aestivum 36.57 2.00e-20 93.60
IUUC-Tbe-127825 Tupaia belangeri 90.79 0.00e+00 1156.00
IUUC-Ttr-128754 Tursiops truncatus 94.89 0.00e+00 1178.00
IUUC-Xtr-132838 Xenopus tropicalis 50.92 0.00e+00 984.00
IUUC-Xma-133119 Xiphophorus maculatus 43.03 0.00e+00 951.00
Created Date 25-Jun-2017

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