iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088920

Ensembl Protein ID

ENSOGAP00000001948.2

UniProt Accession

H0WK75; H0WK75_OTOGA

Genbank Protein ID

ENSOGAP00000001948

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03018817

Gene Name

USP54

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000002177.2	ENSOGAT00000002180.2	ENSOGAP00000001948.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-24	86.3	32	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.....llkalkkeaee 83
           Gl+N   +N+C++NS+LQ+L+++  +r+ + + +++k+  +       ++ ++l+ +f++++ +++++v p++     l k++++e+ +
   Q: 32   GLSNEpgQNSCFLNSALQVLWHLDIFRRSFRQLTTHKCMGD------SCIFCALKGIFNQFQ-CSSEKVLPSDtlrsaLAKTFQDEQ-R 112
           88887668******************************986......59************5.555555555543333555555444.5 PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           f+     Da E+++ ll +++ ++                    de +e+  + ++++ ++ F ++l +q++c +c+ +s    pf+++
   Q: 113  FQLGIMDDAAECFENLLMRIHFHI-------------------ADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPL-PFIQM 181
           99**********************...................3455677899*************************99766.9**** PP
   S: 173  slpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
              ++  + +++             +++ +  ++ +  g+ +   ++c ++ +  +++   + P+++++ L +   s + +  e +  +
   Q: 182  VHYISTTSLCNQAicmlerrekPSPSMFGELLQNASTMGDLRNCPSNCGERIR-IRRVL-MNAPQIITIGLVWD--SDHSDLAEDVIHS 266
           *****999988889999999985556666666677777666667777777664.56655.566**********9..3333444444444 PP
   S: 253  vefpleLdlsp..fctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvl 333
           + +   L+l    f ++ ++  k+++ Y L+++++++G     HY ++  ++k + W++fdD +V+e+  k+++v++++     ++ +l
   Q: 267  LGTC--LKLGDlfFRVT-DDRAKQSELY-LVGMICYYG----KHYSTFFFQTKIRkWMYFDDAHVKEIgpKWKDVVTKCIkghYQPLLL 347
           4444..55555213333.3333335555.*********....9*****99987767************766899988655555555566 PP
   S: 334  fY 335
           +Y
   Q: 348  LY 349
           66 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MSWKRNYFSG GRGSVQGMFA PRSSTSIAPS KGLSNEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTTHKCM GDSCIFCALK GIFNQFQCSS EKVLPSDTLR SALAKTFQDE QRFQLGIMDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTGGA AGAGAAATTA TTTTTCAGGG GGCCGTGGTA GTGTCCAAGG GATGTTTGCA 60
CCTCGAAGCT CAACCTCCAT AGCCCCCAGC AAAGGCCTCA GCAATGAGCC AGGGCAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000820	Aegilops tauschii	29.76	2.00e-18	86.70
IUUC-Aml-001414	Ailuropoda melanoleuca	88.72	0.00e+00	2210.00
IUUC-Atr-002451	Amborella trichopoda	30.35	2.00e-37	152.00
IUUC-Apl-004044	Anas platyrhynchos	81.14	0.00e+00	1236.00
IUUC-Aca-004351	Anolis carolinensis	79.70	0.00e+00	1301.00
IUUC-Aly-005468	Arabidopsis lyrata	32.78	2.00e-43	172.00
IUUC-Ath-007147	Arabidopsis thaliana	32.65	2.00e-42	168.00
IUUC-Ame-011525	Astyanax mexicanus	60.99	0.00e+00	982.00
IUUC-Bta-013344	Bos taurus	85.84	0.00e+00	2156.00
IUUC-Bdi-015058	Brachypodium distachyon	32.13	4.00e-41	164.00
IUUC-Bol-015670	Brassica oleracea	31.78	1.00e-39	158.00
IUUC-Bra-016731	Brassica rapa	32.36	6.00e-42	167.00
IUUC-Cja-018724	Callithrix jacchus	89.06	0.00e+00	2159.00
IUUC-Cfa-021222	Canis familiaris	88.82	0.00e+00	2275.00
IUUC-Cpo-021795	Cavia porcellus	85.98	0.00e+00	2140.00
IUUC-Cre-022697	Chlamydomonas reinhardtii	23.80	2.00e-17	86.70
IUUC-Csa-023262	Chlorocebus sabaeus	89.86	0.00e+00	2194.00
IUUC-Cho-024422	Choloepus hoffmanni	84.64	0.00e+00	2036.00
IUUC-Cin-025752	Ciona intestinalis	68.60	9.00e-49	185.00
IUUC-Csv-026063	Ciona savignyi	56.10	5.00e-112	397.00
IUUC-Dre-028046	Danio rerio	64.04	0.00e+00	957.00
IUUC-Dno-029417	Dasypus novemcinctus	85.10	0.00e+00	2015.00
IUUC-Dor-030653	Dipodomys ordii	73.78	0.00e+00	843.00
IUUC-Dme-032071	Drosophila melanogaster	53.82	2.00e-104	374.00
IUUC-Eca-033235	Equus caballus	87.64	0.00e+00	2222.00
IUUC-Eeu-034975	Erinaceus europaeus	69.70	7.00e-179	620.00
IUUC-Fca-036070	Felis catus	88.29	0.00e+00	2246.00
IUUC-Fal-037089	Ficedula albicollis	64.14	0.00e+00	1523.00
IUUC-Gmo-038653	Gadus morhua	74.67	5.00e-173	600.00
IUUC-Gga-041241	Gallus gallus	64.89	0.00e+00	1560.00
IUUC-Gac-042157	Gasterosteus aculeatus	80.20	0.00e+00	681.00
IUUC-Gma-043273	Glycine max	31.20	1.00e-37	152.00
IUUC-Ggo-045626	Gorilla gorilla	89.86	0.00e+00	2200.00
IUUC-Hsa-045767	Homo sapiens	90.14	0.00e+00	2208.00
IUUC-Hvu-047657	Hordeum vulgare	31.39	6.00e-42	166.00
IUUC-Itr-048187	Ictidomys tridecemlineatus	79.65	0.00e+00	2053.00
IUUC-Lch-049712	Latimeria chalumnae	86.82	0.00e+00	714.00
IUUC-Lpe-051572	Leersia perrieri	32.05	6.00e-39	157.00
IUUC-Loc-052615	Lepisosteus oculatus	66.92	0.00e+00	1018.00
IUUC-Laf-054578	Loxodonta africana	77.81	0.00e+00	1285.00
IUUC-Mcc-054696	Macaca mulatta	90.08	0.00e+00	2205.00
IUUC-Meu-056841	Macropus eugenii	50.21	2.00e-113	404.00
IUUC-Mtr-058682	Medicago truncatula	29.11	4.00e-33	137.00
IUUC-Mga-059519	Meleagris gallopavo	50.39	0.00e+00	999.00
IUUC-Mmr-060701	Microcebus murinus	91.01	0.00e+00	2223.00
IUUC-Mdo-062433	Monodelphis domestica	70.77	0.00e+00	1669.00
IUUC-Mmu-063480	Mus musculus	74.47	0.00e+00	1126.00
IUUC-Mac-064469	Musa acuminata	31.89	4.00e-19	90.90
IUUC-Mpu-066404	Mustela putorius furo	88.50	0.00e+00	2254.00
IUUC-Mlu-067841	Myotis lucifugus	79.43	0.00e+00	1287.00
IUUC-Nle-070110	Nomascus leucogenys	90.22	0.00e+00	2216.00
IUUC-Opr-070676	Ochotona princeps	85.51	0.00e+00	1392.00
IUUC-Ont-072289	Oreochromis niloticus	70.91	0.00e+00	709.00
IUUC-Oan-073551	Ornithorhynchus anatinus	67.93	0.00e+00	1583.00
IUUC-Ocu-074729	Oryctolagus cuniculus	88.36	0.00e+00	2215.00
IUUC-Oba-075174	Oryza barthii	29.82	1.00e-33	139.00
IUUC-Obr-076268	Oryza brachyantha	33.24	3.00e-42	167.00
IUUC-Ogl-077138	Oryza glaberrima	32.35	3.00e-39	157.00
IUUC-Ogu-078705	Oryza glumaepatula	29.82	1.00e-33	139.00
IUUC-Oin-079125	Oryza indica	32.35	3.00e-39	157.00
IUUC-Olo-080872	Oryza longistaminata	29.82	1.00e-33	139.00
IUUC-Ome-081864	Oryza meridionalis	29.82	4.00e-33	138.00
IUUC-Oni-082109	Oryza nivara	29.82	1.00e-33	139.00
IUUC-Opu-083823	Oryza punctata	32.94	7.00e-40	160.00
IUUC-Oru-084310	Oryza rufipogon	29.82	2.00e-33	139.00
IUUC-Osa-085583	Oryza sativa	31.76	2.00e-38	153.00
IUUC-Ola-086742	Oryzias latipes	82.04	0.00e+00	644.00
IUUC-Oar-089644	Ovis aries	85.77	0.00e+00	2160.00
IUUC-Ptr-091530	Pan troglodytes	89.86	0.00e+00	2203.00
IUUC-Pan-092190	Papio anubis	94.26	0.00e+00	1655.00
IUUC-Psi-094022	Pelodiscus sinensis	79.14	0.00e+00	1386.00
IUUC-Pma-094745	Petromyzon marinus	59.89	2.00e-134	471.00
IUUC-Ppa-095930	Physcomitrella patens	29.62	2.00e-38	155.00
IUUC-Pfo-096072	Poecilia formosa	78.70	0.00e+00	696.00
IUUC-Pab-097979	Pongo abelii	90.05	0.00e+00	2138.00
IUUC-Pop-099539	Populus trichocarpa	31.69	9.00e-38	153.00
IUUC-Pca-101005	Procavia capensis	72.89	0.00e+00	1675.00
IUUC-Ppe-101918	Prunus persica	30.90	9.00e-39	156.00
IUUC-Pva-103125	Pteropus vampyrus	87.35	0.00e+00	2234.00
IUUC-Rno-105463	Rattus norvegicus	80.43	0.00e+00	1955.00
IUUC-Sha-107164	Sarcophilus harrisii	70.23	0.00e+00	1571.00
IUUC-Sit-110021	Setaria italica	32.26	2.00e-37	152.00
IUUC-Sly-110975	Solanum lycopersicum	31.21	3.00e-39	158.00
IUUC-Stu-112904	Solanum tuberosum	31.40	2.00e-37	152.00
IUUC-Sar-113423	Sorex araneus	63.68	5.00e-157	548.00
IUUC-Sbi-114345	Sorghum bicolor	32.84	3.00e-41	164.00
IUUC-Ssc-116206	Sus scrofa	86.59	0.00e+00	2084.00
IUUC-Tgu-116521	Taeniopygia guttata	93.98	0.00e+00	787.00
IUUC-Tru-118155	Takifugu rubripes	70.20	1.00e-172	598.00
IUUC-Tsy-118998	Tarsius syrichta	86.45	0.00e+00	2197.00
IUUC-Tni-120257	Tetraodon nigroviridis	80.87	0.00e+00	663.00
IUUC-Tca-121692	Theobroma cacao	31.87	2.00e-38	155.00
IUUC-Tae-125674	Triticum aestivum	31.67	9.00e-43	169.00
IUUC-Tur-126027	Triticum urartu	31.20	1.00e-42	169.00
IUUC-Tbe-128072	Tupaia belangeri	67.67	8.00e-150	524.00
IUUC-Ttr-128290	Tursiops truncatus	85.64	0.00e+00	2035.00
IUUC-Vpa-130213	Vicugna pacos	84.75	0.00e+00	2118.00
IUUC-Vvi-131652	Vitis vinifera	31.20	8.00e-39	156.00
IUUC-Xtr-131831	Xenopus tropicalis	56.51	0.00e+00	1318.00
IUUC-Xma-133409	Xiphophorus maculatus	59.20	0.00e+00	832.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence