iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E1	71.02	3.00e-112	403.00	IUUC-Hsa-046777

Active Site

Position(s)	Description	Evidence
263	Glycyl thioester intermediate	{ECO:0000250}

Organism

Arabidopsis thaliana

Functional Description
(View)

E1-like enzyme which activates UFM1.

Protein Sequence
(Fasta)

MEVGFKALLD DLDVLEKSLS DPALINKLRS HVENLATLSK CNPHRRSKVK ELSSEVVDSN 60
PYSRLMALQR MGIVDNYERI REFSVAIVGI GGVGSVAAEM LTRCGIGRLL LYDYDTVELA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAACGACCC AAGCTTGGCC CATTGTGATC TACAAATATT CATTTTGATC TACAAATTTT 60
TTTAAACGGG CTTTCTAAAG CTACCGTGGC GGTGGCTCGT TCGTCATCCG TCATCTTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc

Interpro

IPR029752--D-isomer_DH_CS1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0008641--F:small protein activating enzyme activity

KEGG

ath:AT1G05350

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001324	Ailuropoda melanoleuca	61.24	2.00e-115	408.00
IUUC-Atr-002660	Amborella trichopoda	76.58	3.00e-152	530.00
IUUC-Apl-003722	Anas platyrhynchos	60.95	2.00e-110	391.00
IUUC-Aca-004584	Anolis carolinensis	59.78	4.00e-116	410.00
IUUC-Aly-005881	Arabidopsis lyrata	95.08	0.00e+00	762.00
IUUC-Ame-011679	Astyanax mexicanus	55.93	1.00e-90	325.00
IUUC-Bta-012517	Bos taurus	62.64	2.00e-120	425.00
IUUC-Bdi-014894	Brachypodium distachyon	74.94	5.00e-154	536.00
IUUC-Bol-016054	Brassica oleracea	94.36	0.00e+00	725.00
IUUC-Bra-016708	Brassica rapa	94.36	0.00e+00	763.00
IUUC-Cel-018424	Caenorhabditis elegans	61.05	4.00e-112	397.00
IUUC-Cja-019825	Callithrix jacchus	71.97	2.00e-96	344.00
IUUC-Cfa-021160	Canis familiaris	61.80	2.00e-116	411.00
IUUC-Cpo-022255	Cavia porcellus	62.36	1.00e-117	415.00
IUUC-Csa-023827	Chlorocebus sabaeus	61.41	1.00e-120	425.00
IUUC-Cho-025078	Choloepus hoffmanni	71.02	2.00e-117	414.00
IUUC-Cin-025217	Ciona intestinalis	58.86	1.00e-112	399.00
IUUC-Dre-027578	Danio rerio	61.16	9.00e-119	419.00
IUUC-Dno-029330	Dasypus novemcinctus	60.34	1.00e-115	409.00
IUUC-Dor-030425	Dipodomys ordii	57.74	2.00e-79	288.00
IUUC-Dme-031645	Drosophila melanogaster	61.16	1.00e-115	408.00
IUUC-Ete-032912	Echinops telfairi	72.92	5.00e-33	134.00
IUUC-Eca-033247	Equus caballus	60.28	1.00e-117	416.00
IUUC-Eeu-034472	Erinaceus europaeus	62.69	5.00e-110	390.00
IUUC-Fca-035684	Felis catus	60.72	1.00e-116	412.00
IUUC-Fal-037654	Ficedula albicollis	60.06	1.00e-115	409.00
IUUC-Gmo-039449	Gadus morhua	58.66	3.00e-88	318.00
IUUC-Gga-041051	Gallus gallus	60.80	4.00e-117	414.00
IUUC-Gac-042325	Gasterosteus aculeatus	61.69	1.00e-120	425.00
IUUC-Gma-043136	Glycine max	79.71	1.00e-170	592.00
IUUC-Ggo-044414	Gorilla gorilla	71.02	4.00e-117	414.00
IUUC-Hsa-046777	Homo sapiens	71.02	6.00e-117	413.00
IUUC-Hvu-047549	Hordeum vulgare	69.94	4.00e-130	456.00
IUUC-Itr-048175	Ictidomys tridecemlineatus	69.62	3.00e-117	414.00
IUUC-Lch-050142	Latimeria chalumnae	60.85	3.00e-119	421.00
IUUC-Lpe-050769	Leersia perrieri	67.17	1.00e-129	455.00
IUUC-Loc-052405	Lepisosteus oculatus	61.10	2.00e-118	417.00
IUUC-Laf-054152	Loxodonta africana	60.85	7.00e-116	409.00
IUUC-Mcc-055618	Macaca mulatta	60.65	1.00e-107	382.00
IUUC-Meu-056486	Macropus eugenii	63.45	8.00e-118	416.00
IUUC-Mtr-057871	Medicago truncatula	76.78	0.00e+00	632.00
IUUC-Mga-059284	Meleagris gallopavo	60.45	1.00e-116	412.00
IUUC-Mmr-061242	Microcebus murinus	62.90	3.00e-121	427.00
IUUC-Mdo-063034	Monodelphis domestica	61.73	2.00e-120	425.00
IUUC-Mmu-064322	Mus musculus	61.69	2.00e-119	421.00
IUUC-Mac-065128	Musa acuminata	73.49	1.00e-90	330.00
IUUC-Mpu-066438	Mustela putorius furo	60.96	2.00e-115	407.00
IUUC-Mlu-067578	Myotis lucifugus	61.41	1.00e-115	409.00
IUUC-Nle-069542	Nomascus leucogenys	60.89	1.00e-116	412.00
IUUC-Opr-070710	Ochotona princeps	70.32	9.00e-114	402.00
IUUC-Ont-072067	Oreochromis niloticus	61.34	5.00e-120	423.00
IUUC-Oan-073593	Ornithorhynchus anatinus	60.53	8.00e-113	399.00
IUUC-Ocu-073964	Oryctolagus cuniculus	60.63	1.00e-110	392.00
IUUC-Oba-075476	Oryza barthii	73.10	1.00e-157	548.00
IUUC-Obr-076517	Oryza brachyantha	75.38	1.00e-157	548.00
IUUC-Ogu-078664	Oryza glumaepatula	72.84	3.00e-157	547.00
IUUC-Olo-081012	Oryza longistaminata	72.84	5.00e-157	546.00
IUUC-Ome-081129	Oryza meridionalis	73.35	1.00e-158	551.00
IUUC-Oni-082265	Oryza nivara	72.08	2.00e-153	534.00
IUUC-Opu-084121	Oryza punctata	72.84	1.00e-155	541.00
IUUC-Oru-084451	Oryza rufipogon	75.47	2.00e-140	491.00
IUUC-Osa-086132	Oryza sativa	73.10	1.00e-157	548.00
IUUC-Ola-086842	Oryzias latipes	61.45	6.00e-116	410.00
IUUC-Oga-088160	Otolemur garnettii	60.72	1.00e-115	409.00
IUUC-Oar-089362	Ovis aries	62.08	2.00e-120	424.00
IUUC-Ptr-091256	Pan troglodytes	61.17	7.00e-117	413.00
IUUC-Pan-092913	Papio anubis	61.41	4.00e-116	410.00
IUUC-Psi-093740	Pelodiscus sinensis	62.20	2.00e-109	388.00
IUUC-Pma-094485	Petromyzon marinus	69.16	4.00e-88	316.00
IUUC-Ppa-095673	Physcomitrella patens	70.17	1.00e-150	525.00
IUUC-Pfo-096196	Poecilia formosa	61.38	2.00e-117	414.00
IUUC-Pab-098449	Pongo abelii	60.61	3.00e-118	417.00
IUUC-Pop-099049	Populus trichocarpa	78.11	5.00e-178	616.00
IUUC-Pca-100917	Procavia capensis	59.82	2.00e-72	265.00
IUUC-Ppe-101797	Prunus persica	77.37	0.00e+00	632.00
IUUC-Pva-102852	Pteropus vampyrus	60.06	2.00e-117	414.00
IUUC-Rno-105213	Rattus norvegicus	61.28	8.00e-121	426.00
IUUC-Sha-107569	Sarcophilus harrisii	61.97	3.00e-118	417.00
IUUC-Smo-109146	Selaginella moellendorffii	66.12	2.00e-142	498.00
IUUC-Sit-109794	Setaria italica	74.06	1.00e-157	549.00
IUUC-Sly-111622	Solanum lycopersicum	76.44	2.00e-170	591.00
IUUC-Stu-112522	Solanum tuberosum	76.91	2.00e-170	590.00
IUUC-Sar-113045	Sorex araneus	54.52	3.00e-99	354.00
IUUC-Sbi-113861	Sorghum bicolor	72.54	3.00e-152	530.00
IUUC-Ssc-115290	Sus scrofa	58.98	5.00e-92	330.00
IUUC-Tgu-117125	Taeniopygia guttata	60.11	7.00e-116	409.00
IUUC-Tru-118041	Takifugu rubripes	61.56	6.00e-120	423.00
IUUC-Tsy-119300	Tarsius syrichta	65.28	4.00e-95	340.00
IUUC-Tni-120310	Tetraodon nigroviridis	69.37	7.00e-112	396.00
IUUC-Tca-121405	Theobroma cacao	78.98	2.00e-171	594.00
IUUC-Tae-123656	Triticum aestivum	73.71	1.00e-161	561.00
IUUC-Tur-125985	Triticum urartu	74.15	1.00e-155	541.00
IUUC-Tbe-127478	Tupaia belangeri	69.64	3.00e-111	394.00
IUUC-Ttr-128169	Tursiops truncatus	72.34	5.00e-95	340.00
IUUC-Vpa-130508	Vicugna pacos	57.06	2.00e-97	348.00
IUUC-Vvi-131252	Vitis vinifera	78.22	1.00e-170	591.00
IUUC-Xtr-132776	Xenopus tropicalis	62.32	6.00e-117	413.00
IUUC-Xma-133110	Xiphophorus maculatus	61.38	1.00e-118	419.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence