iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067277

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02014741

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000012609.2	ENSMLUT00000012612.2	ENSMLUP00000011478.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-28	97.9	307	336
E3 adaptor/Cullin RING/APC_C/CDC20	1.20e-144	481.3	172	478

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWsPDgRHLASGGNDNLVNVW 336
           8***********999*************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss nvlavaL++svylwsa+tgd+ +l ++ +++d+v+svswi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASTGDILQLLQMeQPGDYVSSVSWIKEGNYLAVGTSSAEVQLWDVQQQKR 260
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++t+hsarvgaL Wn+++lssGsr+g+i+h+dvrv+e++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw ++  e    Pl+
   Q: 261  LRNMTSHSARVGALCWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWSPDGRHLASGGNDNLVNVWPSAALEagwvPLQ 349
           *******************************************************************************99999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++ga+l+++d++sqvcs+lws ++kel+s+hGfa+n++++wkyp++ k  +
   Q: 350  TFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGACLNAVDAHSQVCSILWSSHYKELISGHGFAQNQLVIWKYPTKPKKSS 438
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
             gh+aRvlsla+spdg+++++aa+Detlr+w++f+ ++a
   Q: 439  CPGHTARVLSLAMSPDGATVASAAADETLRMWRCFELDPA 478
           ***********************************99876 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAQFVFDSDL HSLLQLDTTI PNAPPARWQR KAKEASGPAS PRRAANRVHT AGRTPGPHSG 60
PGKSGSKIQT TPSKTGGDRY IPHRSATQME VASFLLSKEN NENSQTPTKK EHQKAWALNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCAGT TCGTGTTCGA CAGCGACCTG CACTCCCTGC TGCAGCTGGA CACCACCATC 60
CCCAATGCGC CCCCCGCGCG CTGGCAGCGC AAAGCTAAGG AAGCCTCGGG GCCCGCCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	47.85	1.00e-106	380.00
IUUC-Aml-001545	Ailuropoda melanoleuca	90.22	0.00e+00	867.00
IUUC-Atr-003103	Amborella trichopoda	45.86	2.00e-107	382.00
IUUC-Apl-003255	Anas platyrhynchos	77.90	0.00e+00	732.00
IUUC-Aca-004920	Anolis carolinensis	71.37	0.00e+00	736.00
IUUC-Aly-006303	Arabidopsis lyrata	47.79	5.00e-107	381.00
IUUC-Ath-006795	Arabidopsis thaliana	46.85	7.00e-107	380.00
IUUC-Ate-010479	Aspergillus terreus	50.14	9.00e-95	341.00
IUUC-Bgr-012059	Blumeria graminis	46.82	5.00e-97	348.00
IUUC-Bta-012625	Bos taurus	90.82	0.00e+00	877.00
IUUC-Bci-013607	Botrytis cinerea	50.62	2.00e-98	352.00
IUUC-Bdi-014344	Brachypodium distachyon	47.95	3.00e-107	381.00
IUUC-Bol-015368	Brassica oleracea	45.79	2.00e-105	377.00
IUUC-Bra-016738	Brassica rapa	46.36	5.00e-105	375.00
IUUC-Cja-019132	Callithrix jacchus	90.02	0.00e+00	872.00
IUUC-Cfa-020780	Canis familiaris	89.62	0.00e+00	863.00
IUUC-Cpo-022223	Cavia porcellus	90.22	0.00e+00	822.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	50.00	2.00e-112	399.00
IUUC-Csa-023666	Chlorocebus sabaeus	90.82	0.00e+00	873.00
IUUC-Cho-024920	Choloepus hoffmanni	89.79	3.00e-147	515.00
IUUC-Cin-025675	Ciona intestinalis	48.80	6.00e-129	454.00
IUUC-Csv-026019	Ciona savignyi	48.39	1.00e-124	440.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	40.33	2.00e-98	353.00
IUUC-Cme-027234	Cyanidioschyzon merolae	53.91	1.00e-104	373.00
IUUC-Dre-028026	Danio rerio	57.40	1.00e-170	592.00
IUUC-Dno-028865	Dasypus novemcinctus	88.45	0.00e+00	863.00
IUUC-Dor-030958	Dipodomys ordii	89.42	0.00e+00	863.00
IUUC-Dse-031391	Dothistroma septosporum	50.46	1.00e-98	353.00
IUUC-Dme-031905	Drosophila melanogaster	48.59	1.00e-139	489.00
IUUC-Ete-032387	Echinops telfairi	84.43	0.00e+00	825.00
IUUC-Eca-033522	Equus caballus	80.64	0.00e+00	775.00
IUUC-Eeu-035059	Erinaceus europaeus	78.29	0.00e+00	730.00
IUUC-Fca-036346	Felis catus	90.07	0.00e+00	791.00
IUUC-Fal-037558	Ficedula albicollis	76.24	0.00e+00	760.00
IUUC-Fox-037850	Fusarium oxysporum	46.17	1.00e-97	350.00
IUUC-Fso-038375	Fusarium solani	49.56	4.00e-98	352.00
IUUC-Gmo-039284	Gadus morhua	59.52	3.00e-173	601.00
IUUC-Ggr-039864	Gaeumannomyces graminis	48.84	2.00e-98	353.00
IUUC-Gga-040790	Gallus gallus	75.44	0.00e+00	781.00
IUUC-Gac-041431	Gasterosteus aculeatus	58.89	8.00e-167	580.00
IUUC-Gma-043489	Glycine max	46.25	2.00e-105	375.00
IUUC-Ggo-045052	Gorilla gorilla	90.42	0.00e+00	872.00
IUUC-Hsa-046305	Homo sapiens	90.42	0.00e+00	872.00
IUUC-Hvu-047476	Hordeum vulgare	44.32	1.00e-106	379.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	90.62	0.00e+00	826.00
IUUC-Lch-050174	Latimeria chalumnae	60.43	2.00e-170	592.00
IUUC-Lpe-050954	Leersia perrieri	47.33	2.00e-98	352.00
IUUC-Loc-052638	Lepisosteus oculatus	60.51	3.00e-172	598.00
IUUC-Lma-052998	Leptosphaeria maculans	42.67	5.00e-103	368.00
IUUC-Laf-053742	Loxodonta africana	90.62	0.00e+00	871.00
IUUC-Mcc-054948	Macaca mulatta	90.82	0.00e+00	873.00
IUUC-Meu-056013	Macropus eugenii	82.39	1.00e-134	473.00
IUUC-Mor-057277	Magnaporthe oryzae	52.48	7.00e-96	344.00
IUUC-Mpo-057624	Magnaporthe poae	51.79	2.00e-96	346.00
IUUC-Mtr-057725	Medicago truncatula	46.15	7.00e-98	350.00
IUUC-Mga-060102	Meleagris gallopavo	75.64	0.00e+00	780.00
IUUC-Mmr-061615	Microcebus murinus	90.44	0.00e+00	866.00
IUUC-Mdo-061982	Monodelphis domestica	84.90	0.00e+00	728.00
IUUC-Mmu-063864	Mus musculus	87.43	0.00e+00	854.00
IUUC-Mac-064861	Musa acuminata	46.72	4.00e-107	381.00
IUUC-Mpu-066502	Mustela putorius furo	90.02	0.00e+00	865.00
IUUC-Ncr-068951	Neurospora crassa	46.13	1.00e-95	344.00
IUUC-Nle-070149	Nomascus leucogenys	90.42	0.00e+00	865.00
IUUC-Opr-070778	Ochotona princeps	89.75	0.00e+00	634.00
IUUC-Ont-071660	Oreochromis niloticus	58.05	6.00e-165	573.00
IUUC-Oan-073677	Ornithorhynchus anatinus	72.85	0.00e+00	664.00
IUUC-Ocu-073797	Oryctolagus cuniculus	90.58	0.00e+00	865.00
IUUC-Oba-075946	Oryza barthii	48.07	1.00e-105	377.00
IUUC-Obr-076018	Oryza brachyantha	47.58	3.00e-106	378.00
IUUC-Ogl-077254	Oryza glaberrima	47.33	2.00e-98	352.00
IUUC-Ogu-078521	Oryza glumaepatula	48.29	6.00e-106	378.00
IUUC-Oin-079145	Oryza indica	48.07	9.00e-106	377.00
IUUC-Olo-080798	Oryza longistaminata	48.05	1.00e-105	377.00
IUUC-Ome-081186	Oryza meridionalis	47.83	5.00e-106	379.00
IUUC-Oni-082540	Oryza nivara	48.07	3.00e-105	375.00
IUUC-Opu-084007	Oryza punctata	47.33	3.00e-98	352.00
IUUC-Oru-084562	Oryza rufipogon	48.29	8.00e-106	378.00
IUUC-Osa-086094	Oryza sativa	47.33	2.00e-98	352.00
IUUC-Ola-086907	Oryzias latipes	58.10	4.00e-155	541.00
IUUC-Olu-087647	Ostreococcus lucimarinus	49.31	5.00e-120	424.00
IUUC-Oga-088184	Otolemur garnettii	90.44	0.00e+00	866.00
IUUC-Oar-090023	Ovis aries	86.93	0.00e+00	794.00
IUUC-Ptr-090935	Pan troglodytes	89.68	0.00e+00	810.00
IUUC-Pan-091845	Papio anubis	90.82	0.00e+00	873.00
IUUC-Psi-093188	Pelodiscus sinensis	76.31	0.00e+00	808.00
IUUC-Pma-094187	Petromyzon marinus	52.73	7.00e-141	493.00
IUUC-Pno-094809	Phaeosphaeria nodorum	42.22	6.00e-104	371.00
IUUC-Ppa-095457	Physcomitrella patens	48.62	9.00e-109	387.00
IUUC-Pfo-097429	Poecilia formosa	56.20	5.00e-150	523.00
IUUC-Pab-098603	Pongo abelii	90.62	0.00e+00	872.00
IUUC-Pop-099654	Populus trichocarpa	45.08	1.00e-99	356.00
IUUC-Pca-101062	Procavia capensis	89.42	0.00e+00	850.00
IUUC-Ppe-101865	Prunus persica	46.17	2.00e-94	339.00
IUUC-Pva-102925	Pteropus vampyrus	92.22	0.00e+00	917.00
IUUC-Pte-104142	Pyrenophora teres	42.40	5.00e-102	365.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	41.97	6.00e-102	364.00
IUUC-Rno-106005	Rattus norvegicus	88.02	0.00e+00	855.00
IUUC-Sha-107472	Sarcophilus harrisii	84.83	0.00e+00	839.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	43.13	2.00e-94	339.00
IUUC-Spo-108075	Schizosaccharomyces pombe	45.57	4.00e-97	348.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	51.46	2.00e-97	350.00
IUUC-Smo-108922	Selaginella moellendorffii	48.28	4.00e-121	428.00
IUUC-Sit-110032	Setaria italica	47.60	3.00e-106	378.00
IUUC-Sly-111079	Solanum lycopersicum	46.32	2.00e-103	369.00
IUUC-Stu-112024	Solanum tuberosum	43.28	1.00e-103	369.00
IUUC-Sar-113092	Sorex araneus	85.63	0.00e+00	812.00
IUUC-Sbi-114207	Sorghum bicolor	48.19	5.00e-107	381.00
IUUC-Ssc-115710	Sus scrofa	91.22	0.00e+00	878.00
IUUC-Tgu-117100	Taeniopygia guttata	75.25	0.00e+00	756.00
IUUC-Tru-118184	Takifugu rubripes	56.90	2.00e-131	462.00
IUUC-Tsy-118892	Tarsius syrichta	89.08	1.00e-147	515.00
IUUC-Tni-120474	Tetraodon nigroviridis	57.06	3.00e-156	544.00
IUUC-Tca-120949	Theobroma cacao	45.54	2.00e-104	372.00
IUUC-Tre-122211	Trichoderma reesei	41.11	7.00e-97	347.00
IUUC-Tvi-122531	Trichoderma virens	40.75	1.00e-97	350.00
IUUC-Tae-122819	Triticum aestivum	47.12	2.00e-106	379.00
IUUC-Tur-126193	Triticum urartu	48.19	9.00e-107	380.00
IUUC-Tme-126905	Tuber melanosporum	48.41	2.00e-96	346.00
IUUC-Tbe-127384	Tupaia belangeri	94.18	5.00e-167	580.00
IUUC-Ttr-128511	Tursiops truncatus	90.42	0.00e+00	868.00
IUUC-Vda-129993	Verticillium dahliae	39.47	1.00e-97	350.00
IUUC-Vpa-130775	Vicugna pacos	46.95	4.00e-78	285.00
IUUC-Vvi-131245	Vitis vinifera	46.19	1.00e-93	336.00
IUUC-Xtr-131993	Xenopus tropicalis	71.12	0.00e+00	730.00
IUUC-Xma-133332	Xiphophorus maculatus	59.24	2.00e-165	575.00
IUUC-Yli-134501	Yarrowia lipolytica	50.74	3.00e-101	362.00
IUUC-Zma-135135	Zea mays	46.88	3.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence