iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066502

Ensembl Protein ID

ENSMPUP00000013653.1

UniProt Accession

M3YQP4; M3YQP4_MUSPF

Genbank Protein ID

AER95884.1

Protein Name

Cell division cycle 20-like protein

Genbank Nucleotide ID

AEYP01007503

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000013756.1	ENSMPUT00000013870.1	ENSMPUP00000013653.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	1.40e-146	487.6	172	478
E3 adaptor/Cullin RING/DCX/DWD	9.70e-30	101.4	307	336

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss nvlavaL++svylwsa++gd+ +l ++ +++d+++sv+wi+eg++lavGt+++ev+++Dv+++k+
   Q: 172  PDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMeQPGDYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKR 260
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++t+hsarv++L Wn++++ssGsr+g+i+h+dvrv+e++++tl++h+qevCGl+w+ d+++LasGGnDn v+vw ++  e    Pl+
   Q: 261  LRNMTSHSARVSSLCWNSYIVSSGSRSGQIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEggwvPLQ 349
           ********************************************************************************9999***** PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++ga+l+++d++sqvcs+lws+++kel+s+hGfa+n++++wkyp+++kvae
   Q: 350  TFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAQSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE 438
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           lkgh+aRvlsl++spdg+++++aa+Detlr+w++f+ ++a
   Q: 439  LKGHTARVLSLTMSPDGATVASAAADETLRLWRCFELDPA 478
           ***********************************99876 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+ +v++l++ +d ++l+sG++D+ + vW
   Q: 307  GHSQEVCGLRWaPDgRHLASGGNDNLVNVW 336
           8***********999*************** PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAQFVFESDL HSLLQLDAPI PNAPPARWQR KAKEAAGPVP SPMRAANRSH SAGRTPGRTP 60
GKSSSKTQTT PSKPGGDRYI PHRSASQMEV ASFLLSKENQ PEDSQTPTKK EHQKAWALNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTCGGCGG GCACCCACTC CAAGGACCCC TCCCCTTGCA GACGCTCCCA TGGCGCAGTT 60
CGTGTTCGAG AGCGACCTGC ACTCGCTGCT GCAGCTGGAC GCACCTATCC CCAATGCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0051301--P:cell division
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	46.79	6.00e-110	391.00
IUUC-Aml-001545	Ailuropoda melanoleuca	98.80	0.00e+00	961.00
IUUC-Atr-003103	Amborella trichopoda	46.45	1.00e-108	386.00
IUUC-Apl-003255	Anas platyrhynchos	80.27	0.00e+00	746.00
IUUC-Aca-004920	Anolis carolinensis	76.23	0.00e+00	777.00
IUUC-Aly-006303	Arabidopsis lyrata	48.28	2.00e-108	385.00
IUUC-Ath-006868	Arabidopsis thaliana	47.09	3.00e-106	379.00
IUUC-Ate-010479	Aspergillus terreus	39.78	4.00e-91	328.00
IUUC-Bgr-012059	Blumeria graminis	49.19	3.00e-94	338.00
IUUC-Bta-012625	Bos taurus	97.39	0.00e+00	950.00
IUUC-Bci-013607	Botrytis cinerea	47.37	2.00e-97	350.00
IUUC-Bdi-014344	Brachypodium distachyon	47.28	5.00e-109	387.00
IUUC-Bol-015368	Brassica oleracea	45.65	4.00e-106	379.00
IUUC-Bra-016738	Brassica rapa	46.36	8.00e-106	377.00
IUUC-Cja-019132	Callithrix jacchus	96.39	0.00e+00	945.00
IUUC-Cfa-020780	Canis familiaris	98.00	0.00e+00	954.00
IUUC-Cpo-022223	Cavia porcellus	96.99	0.00e+00	899.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	50.00	6.00e-117	414.00
IUUC-Csa-023666	Chlorocebus sabaeus	97.19	0.00e+00	948.00
IUUC-Cho-024920	Choloepus hoffmanni	96.10	2.00e-160	558.00
IUUC-Cin-025675	Ciona intestinalis	50.40	1.00e-133	469.00
IUUC-Csv-026019	Ciona savignyi	50.75	1.00e-130	459.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	40.56	4.00e-96	345.00
IUUC-Cme-027234	Cyanidioschyzon merolae	51.91	1.00e-105	377.00
IUUC-Dre-028026	Danio rerio	59.56	0.00e+00	626.00
IUUC-Dno-028865	Dasypus novemcinctus	96.40	0.00e+00	936.00
IUUC-Dor-030958	Dipodomys ordii	96.19	0.00e+00	945.00
IUUC-Dse-031391	Dothistroma septosporum	48.50	1.00e-95	343.00
IUUC-Dme-031905	Drosophila melanogaster	49.81	4.00e-144	504.00
IUUC-Ete-032387	Echinops telfairi	91.38	0.00e+00	897.00
IUUC-Eca-033522	Equus caballus	87.37	0.00e+00	850.00
IUUC-Eeu-035059	Erinaceus europaeus	83.80	0.00e+00	787.00
IUUC-Fca-036346	Felis catus	98.19	0.00e+00	873.00
IUUC-Fal-037558	Ficedula albicollis	79.56	0.00e+00	790.00
IUUC-Fox-037850	Fusarium oxysporum	46.54	2.00e-96	346.00
IUUC-Fso-038375	Fusarium solani	44.30	5.00e-97	348.00
IUUC-Gmo-039284	Gadus morhua	61.90	0.00e+00	626.00
IUUC-Ggr-039864	Gaeumannomyces graminis	48.26	8.00e-99	354.00
IUUC-Gga-040790	Gallus gallus	78.94	0.00e+00	807.00
IUUC-Gac-041431	Gasterosteus aculeatus	61.23	3.00e-180	624.00
IUUC-Gma-043489	Glycine max	46.12	8.00e-106	377.00
IUUC-Ggo-045052	Gorilla gorilla	97.60	0.00e+00	949.00
IUUC-Hsa-046305	Homo sapiens	97.60	0.00e+00	949.00
IUUC-Hvu-047476	Hordeum vulgare	45.58	8.00e-110	390.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	97.19	0.00e+00	902.00
IUUC-Lch-050174	Latimeria chalumnae	61.39	8.00e-174	603.00
IUUC-Lpe-050954	Leersia perrieri	46.89	3.00e-100	358.00
IUUC-Loc-052638	Lepisosteus oculatus	62.72	0.00e+00	632.00
IUUC-Lma-052998	Leptosphaeria maculans	42.70	3.00e-100	358.00
IUUC-Laf-053742	Loxodonta africana	97.19	0.00e+00	946.00
IUUC-Mcc-054948	Macaca mulatta	97.19	0.00e+00	948.00
IUUC-Meu-056013	Macropus eugenii	86.57	1.00e-142	499.00
IUUC-Mor-057277	Magnaporthe oryzae	51.82	4.00e-96	345.00
IUUC-Mpo-057624	Magnaporthe poae	51.14	8.00e-97	347.00
IUUC-Mtr-057725	Medicago truncatula	45.60	8.00e-99	353.00
IUUC-Mga-060102	Meleagris gallopavo	79.17	0.00e+00	808.00
IUUC-Mmr-061615	Microcebus murinus	97.70	0.00e+00	946.00
IUUC-Mdo-061982	Monodelphis domestica	88.89	0.00e+00	776.00
IUUC-Mmu-063864	Mus musculus	94.79	0.00e+00	936.00
IUUC-Mac-064861	Musa acuminata	46.97	2.00e-109	389.00
IUUC-Mlu-067277	Myotis lucifugus	89.22	0.00e+00	882.00
IUUC-Ncr-068951	Neurospora crassa	45.07	4.00e-94	338.00
IUUC-Nle-070149	Nomascus leucogenys	97.19	0.00e+00	942.00
IUUC-Opr-070778	Ochotona princeps	94.99	0.00e+00	687.00
IUUC-Ont-071660	Oreochromis niloticus	60.76	2.00e-178	618.00
IUUC-Oan-073677	Ornithorhynchus anatinus	76.89	0.00e+00	705.00
IUUC-Ocu-073797	Oryctolagus cuniculus	96.78	0.00e+00	942.00
IUUC-Oba-075946	Oryza barthii	46.78	2.00e-107	382.00
IUUC-Obr-076018	Oryza brachyantha	46.78	7.00e-108	384.00
IUUC-Ogl-077254	Oryza glaberrima	46.89	2.00e-100	359.00
IUUC-Ogu-078521	Oryza glumaepatula	47.67	3.00e-107	382.00
IUUC-Oin-080094	Oryza indica	46.89	2.00e-100	359.00
IUUC-Olo-080798	Oryza longistaminata	47.42	5.00e-107	382.00
IUUC-Ome-081186	Oryza meridionalis	46.54	3.00e-107	383.00
IUUC-Oni-082243	Oryza nivara	46.89	2.00e-100	359.00
IUUC-Opu-084007	Oryza punctata	47.78	7.00e-100	357.00
IUUC-Oru-084562	Oryza rufipogon	47.67	4.00e-107	382.00
IUUC-Osa-086094	Oryza sativa	46.89	2.00e-100	358.00
IUUC-Ola-086907	Oryzias latipes	60.63	3.00e-166	577.00
IUUC-Olu-087647	Ostreococcus lucimarinus	48.61	1.00e-117	416.00
IUUC-Oga-088184	Otolemur garnettii	95.80	0.00e+00	931.00
IUUC-Oar-090023	Ovis aries	91.88	0.00e+00	842.00
IUUC-Ptr-090935	Pan troglodytes	96.62	0.00e+00	883.00
IUUC-Pan-091845	Papio anubis	97.19	0.00e+00	948.00
IUUC-Psi-093188	Pelodiscus sinensis	80.35	0.00e+00	834.00
IUUC-Pma-094187	Petromyzon marinus	54.56	2.00e-149	522.00
IUUC-Pno-094809	Phaeosphaeria nodorum	41.58	1.00e-100	360.00
IUUC-Ppa-095457	Physcomitrella patens	47.44	1.00e-111	396.00
IUUC-Pfo-097429	Poecilia formosa	58.76	1.00e-161	563.00
IUUC-Pab-098603	Pongo abelii	97.39	0.00e+00	949.00
IUUC-Pop-099654	Populus trichocarpa	45.67	6.00e-102	364.00
IUUC-Pca-101062	Procavia capensis	96.19	0.00e+00	923.00
IUUC-Ppe-101865	Prunus persica	46.06	3.00e-95	342.00
IUUC-Pva-102925	Pteropus vampyrus	95.59	0.00e+00	967.00
IUUC-Pte-104142	Pyrenophora teres	41.94	8.00e-99	354.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	41.77	9.00e-99	354.00
IUUC-Rno-106005	Rattus norvegicus	94.99	0.00e+00	935.00
IUUC-Sha-107472	Sarcophilus harrisii	90.00	0.00e+00	896.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.11	1.00e-92	333.00
IUUC-Spo-108075	Schizosaccharomyces pombe	50.79	2.00e-95	342.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	48.68	7.00e-97	347.00
IUUC-Smo-108922	Selaginella moellendorffii	48.82	9.00e-123	433.00
IUUC-Sit-110732	Setaria italica	46.70	3.00e-109	388.00
IUUC-Sly-111025	Solanum lycopersicum	45.19	2.00e-95	342.00
IUUC-Stu-112676	Solanum tuberosum	45.19	6.00e-97	347.00
IUUC-Sar-113092	Sorex araneus	90.78	0.00e+00	880.00
IUUC-Sbi-114558	Sorghum bicolor	45.71	7.00e-109	387.00
IUUC-Ssc-115710	Sus scrofa	98.00	0.00e+00	955.00
IUUC-Tgu-117100	Taeniopygia guttata	78.57	0.00e+00	789.00
IUUC-Tru-118184	Takifugu rubripes	56.88	9.00e-139	486.00
IUUC-Tsy-118892	Tarsius syrichta	96.81	1.00e-162	565.00
IUUC-Tni-120474	Tetraodon nigroviridis	58.61	5.00e-168	583.00
IUUC-Tca-120949	Theobroma cacao	46.14	3.00e-106	378.00
IUUC-Tre-122211	Trichoderma reesei	40.49	7.00e-97	347.00
IUUC-Tvi-122531	Trichoderma virens	41.06	1.00e-97	350.00
IUUC-Tae-122819	Triticum aestivum	46.79	1.00e-109	390.00
IUUC-Tur-126193	Triticum urartu	45.80	3.00e-110	392.00
IUUC-Tbe-127384	Tupaia belangeri	97.64	4.00e-175	607.00
IUUC-Ttr-128511	Tursiops truncatus	97.80	0.00e+00	949.00
IUUC-Vda-129993	Verticillium dahliae	40.17	9.00e-97	347.00
IUUC-Vpa-130775	Vicugna pacos	46.36	1.00e-78	287.00
IUUC-Vvi-131245	Vitis vinifera	45.68	2.00e-93	336.00
IUUC-Xtr-131993	Xenopus tropicalis	72.71	0.00e+00	747.00
IUUC-Xma-133332	Xiphophorus maculatus	61.93	6.00e-178	617.00
IUUC-Yli-134501	Yarrowia lipolytica	50.15	1.00e-100	360.00
IUUC-Zma-135135	Zea mays	46.93	5.00e-107	381.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence