iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006687

UUCD1 version

UUC-ArT-00757

Ensembl Protein ID

AT4G11680.1

UniProt Accession

Q93Z92; Q9T0D5; RING4_ARATH

Genbank Protein ID

AAY57607.1; CAB39939.1; CAB78211.1; AEE83038.1; AAL15343.1; AAR23720.1

Protein Name

E3 ubiquitin-protein ligase At4g11680; RING finger protein At4g11680; RING-type E3 ubiquitin transferase At4g11680

Genbank Nucleotide ID

DQ059121; AL049500; AL161532; CP002687; AY057713; BT010750

Gene Name

At4g11680; T5C23.110

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G11680	AT4G11680.2	AT4G11680.2
AT4G11680	AT4G11680.1	AT4G11680.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Post-translational Modifications (PTMs)
dbPPT	dbPTM
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	15644464

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	1.90e-06	29.1	338	379

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++++dg  ++ lpC+H+fh +C+ kw         + rCPlC+
   Q: 338  CCICLCEYEDGveLRELPCNHHFHCTCIDKW------LHINSRCPLCK 379
           ********9994455699*************......**********7 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Mediates E2-dependent protein ubiquitination in vitro.

Protein Sequence
(Fasta)

MSSSSSTTTN TTTESDSSSL PTHIGRSNSD GIIDTTPFLP PTVTRTISVD EESNPIHRSA 60
RRQGLREAAR FLRHAGSRRM MREPSMLVRE TAAEQLEERQ SDWAYSKPVV FLDILWNLAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGACACCGA AAACAGGAGG AGAGACCGAG AGAGTATAGG GACCATGGAA ACATCTCCAA 60
AACCTTTTTA ATTTTCCTCA CGTTATCGTT TCTTTATTTC TCTCTCTCTC TCACTTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005774--C:vacuolar membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

ath:AT4G11680

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002539	Amborella trichopoda	62.50	5.00e-101	360.00
IUUC-Aly-006163	Arabidopsis lyrata	88.75	0.00e+00	661.00
IUUC-Bdi-014788	Brachypodium distachyon	62.28	9.00e-111	392.00
IUUC-Bol-015362	Brassica oleracea	85.41	3.00e-162	563.00
IUUC-Bra-017528	Brassica rapa	79.44	8.00e-153	532.00
IUUC-Hvu-047150	Hordeum vulgare	63.86	5.00e-110	389.00
IUUC-Lpe-051532	Leersia perrieri	65.97	8.00e-104	369.00
IUUC-Mac-064658	Musa acuminata	69.37	4.00e-119	420.00
IUUC-Oba-075346	Oryza barthii	64.01	5.00e-109	387.00
IUUC-Ogl-077385	Oryza glaberrima	64.01	5.00e-109	387.00
IUUC-Ogu-078850	Oryza glumaepatula	64.01	6.00e-109	386.00
IUUC-Oin-079121	Oryza indica	65.18	3.00e-96	344.00
IUUC-Ome-081898	Oryza meridionalis	64.31	1.00e-101	362.00
IUUC-Oni-082330	Oryza nivara	64.01	5.00e-109	387.00
IUUC-Opu-083495	Oryza punctata	64.67	1.00e-102	365.00
IUUC-Oru-084814	Oryza rufipogon	64.67	6.00e-109	386.00
IUUC-Osa-085284	Oryza sativa	64.67	6.00e-109	386.00
IUUC-Smo-109047	Selaginella moellendorffii	59.23	6.00e-104	370.00
IUUC-Sit-110740	Setaria italica	66.56	1.00e-97	348.00
IUUC-Sly-111350	Solanum lycopersicum	60.31	5.00e-99	353.00
IUUC-Stu-112030	Solanum tuberosum	59.06	6.00e-109	386.00
IUUC-Tca-121775	Theobroma cacao	69.21	2.00e-122	431.00
IUUC-Tae-124948	Triticum aestivum	64.09	2.00e-114	405.00
IUUC-Tur-126321	Triticum urartu	63.96	7.00e-113	400.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence