iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-14	53.8	1302	1330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDl 30
           + ++claf +  ++l++Gs+D  i v+++
   Q: 1302 GAISCLAFhPHwPHLAVGSNDYYISVYSV 1330
           679******888**************997 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MESEMLQSPL MGLGEEDEAD LTDWNLPLAF MKKRHCEKIE GSKSLAQSWR MKDRMKTVSV 60
ALVLCLNVGV DPPDVVKTTP CARLECWIDP LSMGPQKALE TIGANLQKQY ENWQPRARYK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGACGGAAC GCCGAACTCT CCGCCCTAGC CTGGGTAGAG CGGTGAGAAC GCTTGAAGAG 60
GTTTGGCTTA TTGGACACAC CGTAGACAGC GGTGCATGCT GGGCCTTGGT AATATGGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR029030--Caspase-like_dom
IPR000357--HEAT
IPR004083--Raptor
IPR029347--Raptor_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50294--WD_REPEATS_REGION

Pfam

PF02985--HEAT
PF14538--Raptor_N
PF00400--WD40

SMART

SM01302--Raptor_N
SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0010494--C:cytoplasmic stress granule
GO:0005829--C:cytosol
GO:0005765--C:lysosomal membrane
GO:0005654--C:nucleoplasm
GO:0031931--C:TORC1 complex
GO:0030674--F:protein binding, bridging
GO:0030295--F:protein kinase activator activity
GO:0019901--F:protein kinase binding
GO:0030291--F:protein serine/threonine kinase inhibitor activity
GO:0001030--F:RNA polymerase III type 1 promoter DNA binding
GO:0001031--F:RNA polymerase III type 2 promoter DNA binding
GO:0001032--F:RNA polymerase III type 3 promoter DNA binding
GO:0016049--P:cell growth
GO:0071230--P:cellular response to amino acid stimulus
GO:0009267--P:cellular response to starvation
GO:0030307--P:positive regulation of cell growth
GO:0001938--P:positive regulation of endothelial cell proliferation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0071902--P:positive regulation of protein serine/threonine kinase activity
GO:0032008--P:positive regulation of TOR signaling
GO:0045945--P:positive regulation of transcription from RNA polymerase III promoter
GO:0010506--P:regulation of autophagy
GO:0008361--P:regulation of cell size
GO:0042325--P:regulation of phosphorylation
GO:0031929--P:TOR signaling
GO:0038202--P:TORC1 signaling

KEGG

rno:287871

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000354	Aegilops tauschii	57.30	0.00e+00	676.00
IUUC-Aml-001499	Ailuropoda melanoleuca	96.63	0.00e+00	2559.00
IUUC-Atr-002704	Amborella trichopoda	50.72	0.00e+00	738.00
IUUC-Apl-003540	Anas platyrhynchos	94.67	0.00e+00	2522.00
IUUC-Aca-004449	Anolis carolinensis	96.41	0.00e+00	1372.00
IUUC-Aly-006524	Arabidopsis lyrata	58.86	0.00e+00	762.00
IUUC-Ath-007242	Arabidopsis thaliana	59.11	0.00e+00	763.00
IUUC-Ago-007709	Ashbya gossypii	56.47	6.00e-118	419.00
IUUC-Acl-008215	Aspergillus clavatus	55.69	0.00e+00	766.00
IUUC-Afl-008401	Aspergillus flavus	53.26	0.00e+00	767.00
IUUC-Afu-008797	Aspergillus fumigatus	57.34	0.00e+00	769.00
IUUC-Ani-009268	Aspergillus nidulans	57.34	0.00e+00	765.00
IUUC-Ang-009608	Aspergillus niger	55.77	0.00e+00	756.00
IUUC-Aor-009894	Aspergillus oryzae	53.26	0.00e+00	766.00
IUUC-Ate-010357	Aspergillus terreus	55.49	0.00e+00	767.00
IUUC-Ame-011186	Astyanax mexicanus	86.12	0.00e+00	2121.00
IUUC-Bgr-012085	Blumeria graminis	37.65	0.00e+00	809.00
IUUC-Bta-013422	Bos taurus	97.30	0.00e+00	2596.00
IUUC-Bci-013736	Botrytis cinerea	54.53	0.00e+00	713.00
IUUC-Bdi-015042	Brachypodium distachyon	41.05	0.00e+00	838.00
IUUC-Bol-016048	Brassica oleracea	59.27	0.00e+00	763.00
IUUC-Bra-016961	Brassica rapa	57.66	0.00e+00	778.00
IUUC-Cel-018321	Caenorhabditis elegans	45.31	2.00e-100	361.00
IUUC-Cja-018939	Callithrix jacchus	96.33	0.00e+00	2564.00
IUUC-Cfa-020898	Canis familiaris	96.93	0.00e+00	2574.00
IUUC-Cpo-021514	Cavia porcellus	98.73	0.00e+00	2609.00
IUUC-Cre-022818	Chlamydomonas reinhardtii	63.64	7.00e-111	393.00
IUUC-Csa-023314	Chlorocebus sabaeus	96.93	0.00e+00	2590.00
IUUC-Cin-025701	Ciona intestinalis	72.19	0.00e+00	1000.00
IUUC-Csv-026362	Ciona savignyi	71.79	0.00e+00	993.00
IUUC-Cgl-026561	Colletotrichum gloeosporioides	54.23	0.00e+00	679.00
IUUC-Cne-027009	Cryptococcus neoformans	47.87	0.00e+00	668.00
IUUC-Cme-027253	Cyanidioschyzon merolae	56.36	2.00e-137	484.00
IUUC-Dre-028485	Danio rerio	85.76	0.00e+00	2373.00
IUUC-Dno-029901	Dasypus novemcinctus	93.68	0.00e+00	2305.00
IUUC-Dor-030140	Dipodomys ordii	94.30	0.00e+00	2315.00
IUUC-Dse-031462	Dothistroma septosporum	50.00	0.00e+00	690.00
IUUC-Dme-031670	Drosophila melanogaster	64.09	0.00e+00	866.00
IUUC-Ete-032578	Echinops telfairi	74.16	0.00e+00	777.00
IUUC-Eca-034076	Equus caballus	97.38	0.00e+00	2595.00
IUUC-Eeu-035140	Erinaceus europaeus	92.92	0.00e+00	1168.00
IUUC-Fca-035651	Felis catus	97.08	0.00e+00	2581.00
IUUC-Fal-037244	Ficedula albicollis	94.16	0.00e+00	2476.00
IUUC-Fox-037742	Fusarium oxysporum	54.17	0.00e+00	683.00
IUUC-Fso-038369	Fusarium solani	55.34	0.00e+00	630.00
IUUC-Gmo-039007	Gadus morhua	79.54	0.00e+00	1822.00
IUUC-Ggr-039836	Gaeumannomyces graminis	53.69	0.00e+00	694.00
IUUC-Gga-041121	Gallus gallus	93.45	0.00e+00	2532.00
IUUC-Gac-041430	Gasterosteus aculeatus	87.69	0.00e+00	2341.00
IUUC-Gma-043160	Glycine max	42.20	0.00e+00	905.00
IUUC-Ggo-044934	Gorilla gorilla	98.41	0.00e+00	1416.00
IUUC-Hsa-045887	Homo sapiens	96.78	0.00e+00	2585.00
IUUC-Hvu-047823	Hordeum vulgare	58.18	0.00e+00	756.00
IUUC-Itr-048274	Ictidomys tridecemlineatus	99.28	0.00e+00	807.00
IUUC-Kpa-049399	Komagataella pastoris	59.26	1.00e-124	441.00
IUUC-Lch-050405	Latimeria chalumnae	91.17	0.00e+00	2474.00
IUUC-Lpe-050864	Leersia perrieri	64.81	2.00e-152	533.00
IUUC-Loc-051868	Lepisosteus oculatus	83.87	0.00e+00	2288.00
IUUC-Lma-052993	Leptosphaeria maculans	52.25	0.00e+00	752.00
IUUC-Laf-053339	Loxodonta africana	97.02	0.00e+00	1860.00
IUUC-Mcc-055591	Macaca mulatta	96.93	0.00e+00	2590.00
IUUC-Meu-056642	Macropus eugenii	86.96	0.00e+00	1222.00
IUUC-Mor-057204	Magnaporthe oryzae	53.38	0.00e+00	703.00
IUUC-Mpo-057532	Magnaporthe poae	53.54	0.00e+00	691.00
IUUC-Mtr-058553	Medicago truncatula	42.18	0.00e+00	914.00
IUUC-Mla-058907	Melampsora laricipopulina	44.72	1.00e-151	531.00
IUUC-Mga-059256	Meleagris gallopavo	95.14	0.00e+00	2539.00
IUUC-Mvi-060457	Microbotryum violaceum	49.79	0.00e+00	668.00
IUUC-Mmr-060874	Microcebus murinus	94.44	0.00e+00	2498.00
IUUC-Mdo-062436	Monodelphis domestica	94.31	0.00e+00	2520.00
IUUC-Mmu-063264	Mus musculus	99.85	0.00e+00	2695.00
IUUC-Mac-065524	Musa acuminata	41.86	0.00e+00	848.00
IUUC-Mpu-065899	Mustela putorius furo	95.50	0.00e+00	2353.00
IUUC-Mlu-067344	Myotis lucifugus	94.18	0.00e+00	1909.00
IUUC-Nfi-068615	Neosartorya fischeri	55.98	0.00e+00	768.00
IUUC-Ncr-068744	Neurospora crassa	53.67	0.00e+00	679.00
IUUC-Nle-069014	Nomascus leucogenys	96.33	0.00e+00	2570.00
IUUC-Opr-070548	Ochotona princeps	85.10	0.00e+00	1348.00
IUUC-Ont-072485	Oreochromis niloticus	88.17	0.00e+00	2357.00
IUUC-Oan-073253	Ornithorhynchus anatinus	92.18	0.00e+00	687.00
IUUC-Ocu-074290	Oryctolagus cuniculus	95.70	0.00e+00	822.00
IUUC-Oba-075130	Oryza barthii	56.69	0.00e+00	715.00
IUUC-Obr-076161	Oryza brachyantha	58.15	0.00e+00	753.00
IUUC-Ogl-077800	Oryza glaberrima	50.77	0.00e+00	751.00
IUUC-Ogu-078292	Oryza glumaepatula	64.66	4.00e-47	181.00
IUUC-Oin-080126	Oryza indica	46.45	0.00e+00	647.00
IUUC-Olo-080598	Oryza longistaminata	40.00	1.00e-34	141.00
IUUC-Ome-081293	Oryza meridionalis	47.03	7.00e-141	495.00
IUUC-Oni-082236	Oryza nivara	59.04	3.00e-84	307.00
IUUC-Opu-083423	Oryza punctata	57.44	0.00e+00	739.00
IUUC-Oru-085086	Oryza rufipogon	48.30	0.00e+00	685.00
IUUC-Osa-086012	Oryza sativa	41.53	0.00e+00	822.00
IUUC-Ola-086662	Oryzias latipes	86.23	0.00e+00	2024.00
IUUC-Olu-087760	Ostreococcus lucimarinus	57.49	0.00e+00	720.00
IUUC-Oga-088053	Otolemur garnettii	97.35	0.00e+00	2454.00
IUUC-Oar-089466	Ovis aries	93.23	0.00e+00	2561.00
IUUC-Ptr-090868	Pan troglodytes	96.18	0.00e+00	2578.00
IUUC-Pan-092259	Papio anubis	96.93	0.00e+00	2590.00
IUUC-Psi-093641	Pelodiscus sinensis	94.06	0.00e+00	2364.00
IUUC-Pno-094789	Phaeosphaeria nodorum	52.10	0.00e+00	714.00
IUUC-Ppa-095301	Physcomitrella patens	61.78	0.00e+00	763.00
IUUC-Pfo-096837	Poecilia formosa	86.33	0.00e+00	2353.00
IUUC-Pab-097545	Pongo abelii	95.53	0.00e+00	1272.00
IUUC-Pop-099059	Populus trichocarpa	62.35	0.00e+00	757.00
IUUC-Pca-100579	Procavia capensis	69.85	1.00e-177	617.00
IUUC-Ppe-101494	Prunus persica	58.40	0.00e+00	787.00
IUUC-Pva-103245	Pteropus vampyrus	85.59	0.00e+00	1816.00
IUUC-Pgr-103460	Puccinia graminis	47.29	7.00e-49	190.00
IUUC-Ptt-103797	Puccinia triticina	35.15	7.00e-65	243.00
IUUC-Pte-104367	Pyrenophora teres	52.95	0.00e+00	745.00
IUUC-Pyt-104771	Pyrenophora triticirepentis	50.22	0.00e+00	691.00
IUUC-Sce-106156	Saccharomyces cerevisiae	55.61	3.00e-119	424.00
IUUC-Sha-106474	Sarcophilus harrisii	94.41	0.00e+00	2011.00
IUUC-Sja-107888	Schizosaccharomyces japonicus	57.98	0.00e+00	774.00
IUUC-Spo-108057	Schizosaccharomyces pombe	56.79	0.00e+00	752.00
IUUC-Ssl-108423	Sclerotinia sclerotiorum	54.53	0.00e+00	717.00
IUUC-Smo-109059	Selaginella moellendorffii	55.93	0.00e+00	750.00
IUUC-Sit-109752	Setaria italica	57.80	0.00e+00	746.00
IUUC-Sly-110910	Solanum lycopersicum	56.58	0.00e+00	773.00
IUUC-Stu-112814	Solanum tuberosum	56.15	0.00e+00	765.00
IUUC-Sbi-113810	Sorghum bicolor	58.00	0.00e+00	747.00
IUUC-Sre-115168	Sporisorium reilianum	42.83	0.00e+00	684.00
IUUC-Ssc-115398	Sus scrofa	93.92	0.00e+00	1923.00
IUUC-Tgu-117361	Taeniopygia guttata	93.45	0.00e+00	2423.00
IUUC-Tsy-119587	Tarsius syrichta	98.93	0.00e+00	1155.00
IUUC-Tni-119757	Tetraodon nigroviridis	86.08	0.00e+00	2310.00
IUUC-Tca-121570	Theobroma cacao	62.77	0.00e+00	765.00
IUUC-Tre-122024	Trichoderma reesei	56.16	0.00e+00	639.00
IUUC-Tvi-122502	Trichoderma virens	55.67	0.00e+00	642.00
IUUC-Tae-125799	Triticum aestivum	58.18	0.00e+00	757.00
IUUC-Tme-127001	Tuber melanosporum	55.88	2.00e-154	540.00
IUUC-Ttr-129128	Tursiops truncatus	87.79	0.00e+00	2265.00
IUUC-Uma-129588	Ustilago maydis	44.93	0.00e+00	683.00
IUUC-Vda-129990	Verticillium dahliae	53.75	3.00e-180	626.00
IUUC-Vvi-131611	Vitis vinifera	42.20	0.00e+00	919.00
IUUC-Xtr-132727	Xenopus tropicalis	91.74	0.00e+00	2456.00
IUUC-Xma-133492	Xiphophorus maculatus	87.88	0.00e+00	2379.00
IUUC-Yli-134358	Yarrowia lipolytica	55.24	0.00e+00	696.00
IUUC-Zma-135723	Zea mays	57.62	0.00e+00	679.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence