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Tag Content
UUCD2 ID IUUC-Itr-048169
UUCD1 version UUC-SpT-00318
Ensembl Protein ID ENSSTOP00000001431.2
UniProt Accession I3LYV9; I3LYV9_ICTTR
Genbank Protein ID ENSSTOP00000001431
Protein Name Uncharacterized protein
Genbank Nucleotide ID AGTP01066811
Gene Name PRPF19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000001598.2 ENSSTOT00000001600.2 ENSSTOP00000001431.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.20e-32 108.3 390 423
E3 activity/RING/U-box 1.50e-15 57.0 3 64
UBD/Beta-Prp 8.90e-54 182.7 231 461
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH++++t++af  ++ +l++++dD ++k+WDlr+
   Q: 390  GHSGPITSIAFseNGYYLATAADDSSVKLWDLRK 423
           8**********976699**************986 PP
   

   E3 activity/RING/U-box
   S: 6    flCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqa 67
           ++C+Is+e++++P+v+p s+++y+r+ Iek++a++g+ +P+++qpl+ee+l++ ++ + +  +
   Q: 3    LICSISNEVPEHPCVSPvSNHVYERRLIEKYIAENGT-DPINNQPLSEEQLIDIKVAHPIRPK 64
           79**********************************9.***************9998877665 PP
   

   UBD/Beta-Prp
   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
             d++ ++tg++d+ + v+d ++++ l++l+gh+++vt+v f+p++++  ++s D+ti++w++ + +cv+++++he+ v+ ls++++gd
   Q: 231  PSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGD 319
           568899*********************************************************************************** PP
   S: 108  klvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkel 195
           +l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G+ D+++++Wdlk  + +  + g h ++++s++f++ng +l
   Q: 320  YLLSSSDDQYWAFSDIQTGRVLTKvTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYL 407
           **********************997777777789************************************9.***************** PP
   S: 196  vsgsldgtvklwdlqtgecvrtlnghtd.nvksvrfspnderlvsgssDgsiri 248
           +++++d++vklwdl++ +  +tl+  ++  vks+ f++ +++l+ g+ D +i+i
   Q: 408  ATAADDSSVKLWDLRKLKNFKTLQLDNNfEVKSLIFDQSGTYLALGGTDVQIYI 461
           ***************999999999866527*******************99987 PP
   
Organism Ictidomys tridecemlineatus
Protein Sequence
(Fasta)
MSLICSISNE VPEHPCVSPV SNHVYERRLI EKYIAENGTD PINNQPLSEE QLIDIKVAHP 60
IRPKPPSATS IPAILKALQD EWDAVMLHSF TLRQQLQTTR QELSHALYQH DAACRVIARL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Itr-048169|E3,WD_repeat;E3,U-box;UBD,Beta-Prp|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCCAGGCCT CACCTTCTTG ACGTCGGACT TTGGGGCTTA AAATCTTGCA CGAGTTTGAG 60
AGTGTAAGCA TGTATGAGAA ATCATATTTC AAACATCGCG GGCAGTAAAG CCAATGACTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Itr-048169|E3,WD_repeat;E3,U-box;UBD,Beta-Prp|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50231--RICIN_B_LECTIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00504--Ubox
SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0005662--C:DNA replication factor A complex
GO:0005811--C:lipid particle
GO:0016020--C:membrane
GO:0016607--C:nuclear speck
GO:0000974--C:Prp19 complex
GO:0035861--C:site of double-strand break
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0034613--P:cellular protein localization
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0001833--P:inner cell mass cell proliferation
GO:0008610--P:lipid biosynthetic process
GO:0045665--P:negative regulation of neuron differentiation
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0048026--P:positive regulation of mRNA splicing, via spliceosome
GO:0010498--P:proteasomal protein catabolic process
GO:0070534--P:protein K63-linked ubiquitination
GO:0072422--P:signal transduction involved in DNA damage checkpoint
GO:0000245--P:spliceosomal complex assembly
GO:0000244--P:spliceosomal tri-snRNP complex assembly
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000488 Aegilops tauschii 39.73 7.00e-97 348.00
IUUC-Aml-001230 Ailuropoda melanoleuca 95.59 0.00e+00 954.00
IUUC-Atr-002594 Amborella trichopoda 44.17 3.00e-119 421.00
IUUC-Apl-003686 Anas platyrhynchos 87.62 0.00e+00 731.00
IUUC-Aca-005272 Anolis carolinensis 97.02 0.00e+00 999.00
IUUC-Aly-005586 Arabidopsis lyrata 44.10 1.00e-119 423.00
IUUC-Ath-007696 Arabidopsis thaliana 44.19 1.00e-115 409.00
IUUC-Acl-008335 Aspergillus clavatus 35.74 2.00e-68 253.00
IUUC-Afl-008527 Aspergillus flavus 38.19 3.00e-73 268.00
IUUC-Afu-008957 Aspergillus fumigatus 37.78 3.00e-79 288.00
IUUC-Ani-009280 Aspergillus nidulans 37.45 4.00e-67 248.00
IUUC-Ang-009746 Aspergillus niger 36.50 1.00e-67 249.00
IUUC-Aor-009905 Aspergillus oryzae 37.97 6.00e-77 281.00
IUUC-Ate-010412 Aspergillus terreus 37.34 9.00e-66 244.00
IUUC-Ame-011561 Astyanax mexicanus 85.00 1.00e-111 395.00
IUUC-Bgr-012283 Blumeria graminis 32.85 8.00e-57 214.00
IUUC-Bta-013242 Bos taurus 99.21 0.00e+00 1012.00
IUUC-Bci-013901 Botrytis cinerea 33.80 2.00e-65 242.00
IUUC-Bdi-014277 Brachypodium distachyon 43.95 4.00e-124 438.00
IUUC-Bol-016207 Brassica oleracea 45.54 9.00e-119 420.00
IUUC-Bra-017902 Brassica rapa 43.52 4.00e-117 414.00
IUUC-Cel-018271 Caenorhabditis elegans 51.38 4.00e-152 530.00
IUUC-Cja-019879 Callithrix jacchus 99.01 0.00e+00 1006.00
IUUC-Cfa-020175 Canis familiaris 98.81 0.00e+00 1009.00
IUUC-Cpo-022379 Cavia porcellus 99.21 0.00e+00 1012.00
IUUC-Cre-022993 Chlamydomonas reinhardtii 40.16 2.00e-99 355.00
IUUC-Csa-023500 Chlorocebus sabaeus 99.40 0.00e+00 1013.00
IUUC-Cho-025065 Choloepus hoffmanni 87.14 1.00e-148 518.00
IUUC-Cin-025699 Ciona intestinalis 68.35 6.00e-176 609.00
IUUC-Csv-026128 Ciona savignyi 65.58 0.00e+00 682.00
IUUC-Cgl-026507 Colletotrichum gloeosporioides 33.20 1.00e-65 243.00
IUUC-Cne-026860 Cryptococcus neoformans 37.38 1.00e-93 336.00
IUUC-Dre-028187 Danio rerio 84.55 0.00e+00 862.00
IUUC-Dno-029453 Dasypus novemcinctus 99.21 0.00e+00 1011.00
IUUC-Dor-030150 Dipodomys ordii 98.74 2.00e-128 452.00
IUUC-Dse-031220 Dothistroma septosporum 32.29 2.00e-58 219.00
IUUC-Dme-031906 Drosophila melanogaster 65.54 0.00e+00 664.00
IUUC-Ete-033035 Echinops telfairi 86.71 0.00e+00 860.00
IUUC-Eca-033478 Equus caballus 99.01 0.00e+00 1009.00
IUUC-Eeu-034974 Erinaceus europaeus 99.39 0.00e+00 679.00
IUUC-Fca-036194 Felis catus 98.01 0.00e+00 998.00
IUUC-Fal-037417 Ficedula albicollis 96.83 0.00e+00 996.00
IUUC-Fox-037922 Fusarium oxysporum 34.46 3.00e-65 241.00
IUUC-Fso-038256 Fusarium solani 34.27 4.00e-66 245.00
IUUC-Gmo-038713 Gadus morhua 85.94 0.00e+00 879.00
IUUC-Ggr-039854 Gaeumannomyces graminis 32.44 4.00e-55 208.00
IUUC-Gga-041143 Gallus gallus 97.02 0.00e+00 997.00
IUUC-Gac-042129 Gasterosteus aculeatus 84.55 0.00e+00 890.00
IUUC-Gma-044273 Glycine max 45.68 8.00e-121 427.00
IUUC-Ggo-045262 Gorilla gorilla 99.40 0.00e+00 1013.00
IUUC-Hsa-046036 Homo sapiens 99.40 0.00e+00 1013.00
IUUC-Hvu-047442 Hordeum vulgare 43.12 5.00e-69 253.00
IUUC-Lch-050105 Latimeria chalumnae 89.88 0.00e+00 939.00
IUUC-Lpe-050976 Leersia perrieri 44.62 2.00e-120 426.00
IUUC-Loc-052042 Lepisosteus oculatus 73.99 0.00e+00 664.00
IUUC-Lma-053143 Leptosphaeria maculans 34.38 1.00e-64 241.00
IUUC-Laf-053451 Loxodonta africana 95.78 0.00e+00 1001.00
IUUC-Mcc-055786 Macaca mulatta 99.40 0.00e+00 1013.00
IUUC-Meu-056161 Macropus eugenii 98.34 2.00e-140 492.00
IUUC-Mor-057215 Magnaporthe oryzae 33.66 6.00e-58 218.00
IUUC-Mpo-057419 Magnaporthe poae 31.29 1.00e-51 196.00
IUUC-Mtr-057756 Medicago truncatula 43.88 4.00e-116 411.00
IUUC-Mla-059085 Melampsora laricipopulina 38.20 2.00e-86 312.00
IUUC-Mga-060158 Meleagris gallopavo 90.18 0.00e+00 883.00
IUUC-Mvi-060441 Microbotryum violaceum 38.12 1.00e-78 286.00
IUUC-Mmr-061085 Microcebus murinus 99.40 0.00e+00 1013.00
IUUC-Mdo-061804 Monodelphis domestica 99.01 0.00e+00 1011.00
IUUC-Mmu-063608 Mus musculus 95.60 0.00e+00 999.00
IUUC-Mac-064972 Musa acuminata 44.04 8.00e-117 413.00
IUUC-Mpu-065700 Mustela putorius furo 98.81 0.00e+00 1009.00
IUUC-Mlu-068223 Myotis lucifugus 94.41 0.00e+00 986.00
IUUC-Nfi-068504 Neosartorya fischeri 37.58 6.00e-79 287.00
IUUC-Ncr-068729 Neurospora crassa 36.69 9.00e-64 237.00
IUUC-Nle-069754 Nomascus leucogenys 99.40 0.00e+00 1013.00
IUUC-Opr-070621 Ochotona princeps 95.17 0.00e+00 948.00
IUUC-Ont-071377 Oreochromis niloticus 84.55 0.00e+00 871.00
IUUC-Oan-073498 Ornithorhynchus anatinus 72.92 3.00e-122 431.00
IUUC-Ocu-074182 Oryctolagus cuniculus 95.43 0.00e+00 1000.00
IUUC-Oba-075509 Oryza barthii 43.95 3.00e-122 431.00
IUUC-Obr-076480 Oryza brachyantha 44.34 3.00e-123 435.00
IUUC-Ogl-077052 Oryza glaberrima 43.95 3.00e-122 432.00
IUUC-Ogu-078919 Oryza glumaepatula 43.95 3.00e-122 431.00
IUUC-Oin-079357 Oryza indica 43.24 2.00e-115 409.00
IUUC-Olo-080376 Oryza longistaminata 43.44 4.00e-110 391.00
IUUC-Ome-081973 Oryza meridionalis 43.24 3.00e-110 391.00
IUUC-Oni-082849 Oryza nivara 44.15 6.00e-123 434.00
IUUC-Opu-083243 Oryza punctata 43.76 1.00e-121 429.00
IUUC-Oru-084613 Oryza rufipogon 43.95 5.00e-122 431.00
IUUC-Osa-085407 Oryza sativa 43.93 8.00e-122 430.00
IUUC-Ola-086566 Oryzias latipes 83.73 0.00e+00 862.00
IUUC-Olu-087757 Ostreococcus lucimarinus 39.12 1.00e-94 340.00
IUUC-Oga-089010 Otolemur garnettii 94.67 0.00e+00 959.00
IUUC-Oar-089638 Ovis aries 99.21 0.00e+00 1012.00
IUUC-Ptr-091141 Pan troglodytes 99.40 0.00e+00 1013.00
IUUC-Pan-092662 Papio anubis 99.40 0.00e+00 1013.00
IUUC-Psi-093777 Pelodiscus sinensis 96.66 0.00e+00 819.00
IUUC-Pno-095115 Phaeosphaeria nodorum 34.81 2.00e-65 243.00
IUUC-Ppa-095841 Physcomitrella patens 44.79 1.00e-120 426.00
IUUC-Pfo-096390 Poecilia formosa 84.16 0.00e+00 870.00
IUUC-Pab-098250 Pongo abelii 97.73 0.00e+00 946.00
IUUC-Pop-099854 Populus trichocarpa 44.89 5.00e-120 424.00
IUUC-Pca-100553 Procavia capensis 98.81 0.00e+00 1004.00
IUUC-Ppe-101383 Prunus persica 44.40 2.00e-115 409.00
IUUC-Pva-102189 Pteropus vampyrus 99.01 0.00e+00 1010.00
IUUC-Pgr-103304 Puccinia graminis 36.93 2.00e-84 306.00
IUUC-Ptt-103984 Puccinia triticina 37.88 1.00e-89 323.00
IUUC-Pte-104385 Pyrenophora teres 33.12 5.00e-69 254.00
IUUC-Pyt-104697 Pyrenophora triticirepentis 33.54 3.00e-70 258.00
IUUC-Rno-105581 Rattus norvegicus 99.21 0.00e+00 1013.00
IUUC-Sha-107071 Sarcophilus harrisii 94.87 0.00e+00 997.00
IUUC-Sja-107697 Schizosaccharomyces japonicus 31.34 6.00e-36 144.00
IUUC-Spo-108315 Schizosaccharomyces pombe 32.63 3.00e-46 179.00
IUUC-Ssl-108628 Sclerotinia sclerotiorum 35.16 7.00e-65 241.00
IUUC-Smo-109648 Selaginella moellendorffii 44.77 2.00e-121 428.00
IUUC-Sit-109873 Setaria italica 43.76 5.00e-120 424.00
IUUC-Sly-111673 Solanum lycopersicum 45.00 3.00e-113 401.00
IUUC-Stu-112125 Solanum tuberosum 44.77 5.00e-112 397.00
IUUC-Sbi-114696 Sorghum bicolor 41.98 2.00e-108 385.00
IUUC-Sre-115134 Sporisorium reilianum 31.75 9.00e-72 264.00
IUUC-Ssc-116260 Sus scrofa 99.01 0.00e+00 1011.00
IUUC-Tgu-116533 Taeniopygia guttata 97.02 0.00e+00 997.00
IUUC-Tru-117800 Takifugu rubripes 83.96 0.00e+00 892.00
IUUC-Tsy-118980 Tarsius syrichta 93.47 0.00e+00 918.00
IUUC-Tni-120334 Tetraodon nigroviridis 67.92 0.00e+00 702.00
IUUC-Tca-121807 Theobroma cacao 44.12 4.00e-121 428.00
IUUC-Tre-121920 Trichoderma reesei 33.40 1.00e-63 236.00
IUUC-Tvi-122294 Trichoderma virens 33.05 6.00e-56 211.00
IUUC-Tae-125713 Triticum aestivum 44.34 4.00e-125 441.00
IUUC-Tur-126664 Triticum urartu 39.89 1.00e-114 406.00
IUUC-Tme-127026 Tuber melanosporum 34.28 1.00e-68 253.00
IUUC-Tbe-127582 Tupaia belangeri 99.70 0.00e+00 679.00
IUUC-Ttr-128313 Tursiops truncatus 98.81 0.00e+00 1001.00
IUUC-Uma-129626 Ustilago maydis 33.15 2.00e-74 273.00
IUUC-Vda-129699 Verticillium dahliae 35.36 4.00e-68 251.00
IUUC-Vpa-130593 Vicugna pacos 98.46 0.00e+00 898.00
IUUC-Vvi-131668 Vitis vinifera 44.32 1.00e-119 423.00
IUUC-Xtr-132186 Xenopus tropicalis 85.19 0.00e+00 768.00
IUUC-Xma-133212 Xiphophorus maculatus 83.76 0.00e+00 865.00
IUUC-Yli-134607 Yarrowia lipolytica 57.58 2.00e-41 160.00
IUUC-Zma-135662 Zea mays 45.00 2.00e-122 432.00
Created Date 25-Jun-2017

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