iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121337

Ensembl Protein ID

EOY09670

UniProt Accession

A0A061EXA0; A0A061EXA0_THECC

Genbank Protein ID

EOY09670.1

Protein Name

Transducin family protein / WD-40 repeat family protein isoform 1

Genbank Nucleotide ID

CM001883

Gene Name

TCM_025065

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_025065	EOY09670	EOY09670

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	1.50e-117	393.2	116	424
E3 adaptor/Cullin RING/DCX/DWD	1.10e-22	80.1	302	341

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtl...tghsar 98
           e+ ldape+ ddfylnLldW+ +nvla+aL+ +vylw+a++g+ s+l  +  e+  +tsvsw ++g ++a+G ++++v+++D++ k+++rtl   + h +r
   Q: 116  ERTLDAPEILDDFYLNLLDWGCNNVLAIALNDKVYLWDASNGSASELVTVsYEDGPITSVSWAPDGRHIAIGLNNSHVQLWDCQVKRQLRTLrggHHHETR 216
           689**********************************************9788889************************************64445789* PP
   S: 99   vgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse......PlkkfkehkaavkaiawsPwqks 193
           v +L+Wn+++l++G+ d ++  +dvrv+e++++ + +h+ evCGlkw++++k+LasGGnDn + +wd            l++ ++h+aavkaiaw+P+q +
   Q: 217  VNTLAWNNHILTTGGMDAKVINNDVRVREHTVACYMGHQLEVCGLKWSSSGKQLASGGNDNLLFIWDRFMAPsnsrtqWLHRLDDHTAAVKAIAWCPFQGN 317
           ******************************************************************975433234455889999***************** PP
   S: 194  lLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivtaagDetlrfw 294
           lLasGGG +D+ci+fwnt tg +l+++dtgsqvc llw k+++el+s+hGf++n+++lwkyps+ k+ael gh++R l++a spdg +++taagDetlr+w
   Q: 318  LLASGGGGSDQCIRFWNTHTGVCLNSVDTGSQVCALLWNKHERELLSSHGFTDNQLILWKYPSMRKMAELLGHTSRALYMAESPDGCTVATAAGDETLRLW 418
           ***************************************************************************************************** PP
   S: 295  klfdkk 300
           ++f + 
   Q: 419  NVFGTP 424
           ***875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGs..dDgtikvWDlrtgvll 36
           Ht+ v ++a+   +++ll+sG+   D  i+ W+++tgv+l
   Q: 302  HTAAVKAIAWcpfQGNLLASGGggSDQCIRFWNTHTGVCL 341
           9**********98669****5555***************8 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MHSRTPLQEL LLQRRNTQDD LDRFIPNRSA MDFDYAHYML TEGRKGIEKP DIIGSPSREA 60
YQKRLAEALN MNRTRILAFK NKPPTSDGDG MIHREMGSPH QSKSTKKRRH ISQTSERTLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCATTCAA GAACCCCACT TCAAGAACTA CTTCTTCAAA GAAGAAACAC CCAAGACGAT 60
GTAAGTAACA CAAAGCAAAT ATTTTGATTC CTTTAGATTC TTTGTTTTTT TTTGGGGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

tcc:TCM_025065

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cne-026872	Cryptococcus neoformans	39.33	2.00e-85	308.00
IUUC-Cme-027234	Cyanidioschyzon merolae	44.62	4.00e-101	360.00
IUUC-Ggr-039864	Gaeumannomyces graminis	44.76	5.00e-93	334.00
IUUC-Mpo-057624	Magnaporthe poae	44.24	2.00e-90	325.00
IUUC-Tru-118184	Takifugu rubripes	42.65	5.00e-90	323.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence