iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021323

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02039593

Gene Name

UBE2A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000011908.3	ENSCPOT00000012023.2	ENSCPOP00000010713.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.30e-55	185.6	8	142

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++++k+l++dpp+g+s  p+++ +++ w+++i+Gpe+tp+e+g+Fkl+ief+e+YP kPP+v+f++k+fhPnvy++G++Cl+il+  
   Q: 8    RLMRDFKRLQEDPPAGVSGAPSEN-NIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFISKMFHPNVYADGSICLDILQ-- 93
           9**********************9.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 94   NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 142
           **********************************************996 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSTPARRRLM RDFKRLQEDP PAGVSGAPSE NNIMVWNAVI FGPEGTPFED GTFKLTIEFT 60
EEYPNKPPTV RFISKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCACCC CGGCTCGGCG GCGCCTCATG AGGGACTTCA AGAGGTAAAC CGTCGGGGCG 60
AAGGAGGCCG GGGGCACAGG GCGGGTCCCC AGCGGACCCT GAGGGCGGGA GTGGGGGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006281--P:DNA repair
GO:0033522--P:histone H2A ubiquitination
GO:0001701--P:in utero embryonic development
GO:0060135--P:maternal process involved in female pregnancy
GO:0008284--P:positive regulation of cell proliferation
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001001	Aegilops tauschii	76.51	6.00e-70	255.00
IUUC-Atr-002862	Amborella trichopoda	78.52	1.00e-71	261.00
IUUC-Aly-005584	Arabidopsis lyrata	76.51	1.00e-70	258.00
IUUC-Ath-007149	Arabidopsis thaliana	76.51	1.00e-70	258.00
IUUC-Ago-007745	Ashbya gossypii	69.80	6.00e-63	232.00
IUUC-Afl-008551	Aspergillus flavus	69.54	8.00e-64	235.00
IUUC-Afu-008980	Aspergillus fumigatus	69.54	8.00e-64	235.00
IUUC-Ang-009554	Aspergillus niger	69.54	8.00e-64	235.00
IUUC-Aor-010242	Aspergillus oryzae	69.54	8.00e-64	235.00
IUUC-Ate-010390	Aspergillus terreus	69.54	8.00e-64	235.00
IUUC-Ame-011594	Astyanax mexicanus	99.34	2.00e-88	317.00
IUUC-Bgr-012039	Blumeria graminis	67.65	1.00e-56	211.00
IUUC-Bci-013919	Botrytis cinerea	70.20	7.00e-65	238.00
IUUC-Bdi-015010	Brachypodium distachyon	77.85	6.00e-71	259.00
IUUC-Bol-016084	Brassica oleracea	77.85	2.00e-71	260.00
IUUC-Bra-016643	Brassica rapa	77.85	2.00e-71	260.00
IUUC-Cel-018244	Caenorhabditis elegans	86.58	6.00e-78	283.00
IUUC-Cja-018783	Callithrix jacchus	99.34	2.00e-88	317.00
IUUC-Cfa-020646	Canis familiaris	99.34	3.00e-87	313.00
IUUC-Csa-023588	Chlorocebus sabaeus	99.34	2.00e-88	317.00
IUUC-Cin-025537	Ciona intestinalis	82.24	9.00e-63	231.00
IUUC-Csv-025846	Ciona savignyi	83.22	3.00e-67	246.00
IUUC-Cgl-026381	Colletotrichum gloeosporioides	69.54	2.00e-64	237.00
IUUC-Cne-026864	Cryptococcus neoformans	72.48	3.00e-65	240.00
IUUC-Cme-027284	Cyanidioschyzon merolae	68.00	1.00e-54	206.00
IUUC-Dre-028358	Danio rerio	99.34	2.00e-88	317.00
IUUC-Dse-031487	Dothistroma septosporum	69.54	4.00e-64	236.00
IUUC-Dme-031863	Drosophila melanogaster	87.42	6.00e-78	282.00
IUUC-Eca-033562	Equus caballus	97.40	9.00e-87	311.00
IUUC-Eeu-035191	Erinaceus europaeus	79.22	2.00e-64	237.00
IUUC-Fca-036581	Felis catus	99.34	2.00e-88	317.00
IUUC-Fal-037474	Ficedula albicollis	99.16	1.00e-68	250.00
IUUC-Fox-037808	Fusarium oxysporum	69.54	3.00e-64	236.00
IUUC-Fso-038232	Fusarium solani	69.54	3.00e-64	236.00
IUUC-Gmo-038517	Gadus morhua	99.34	2.00e-88	317.00
IUUC-Ggr-039875	Gaeumannomyces graminis	69.80	2.00e-63	234.00
IUUC-Gga-040588	Gallus gallus	99.34	2.00e-88	317.00
IUUC-Gac-041504	Gasterosteus aculeatus	99.34	4.00e-88	315.00
IUUC-Gma-043883	Glycine max	78.52	9.00e-72	261.00
IUUC-Ggo-044896	Gorilla gorilla	99.34	2.00e-88	317.00
IUUC-Hsa-046383	Homo sapiens	99.34	2.00e-88	317.00
IUUC-Hvu-047054	Hordeum vulgare	76.51	6.00e-70	255.00
IUUC-Itr-048507	Ictidomys tridecemlineatus	99.34	2.00e-88	317.00
IUUC-Kpa-049225	Komagataella pastoris	69.80	1.00e-62	231.00
IUUC-Lch-049964	Latimeria chalumnae	99.34	2.00e-88	317.00
IUUC-Lpe-051301	Leersia perrieri	78.52	1.00e-71	261.00
IUUC-Loc-051731	Lepisosteus oculatus	99.34	2.00e-88	317.00
IUUC-Laf-053680	Loxodonta africana	99.34	2.00e-88	317.00
IUUC-Mcc-055546	Macaca mulatta	99.34	5.00e-88	317.00
IUUC-Meu-056231	Macropus eugenii	99.34	2.00e-88	317.00
IUUC-Mor-057087	Magnaporthe oryzae	67.41	9.00e-55	205.00
IUUC-Mpo-057498	Magnaporthe poae	69.80	2.00e-63	234.00
IUUC-Mtr-058305	Medicago truncatula	78.52	8.00e-72	262.00
IUUC-Mla-058876	Melampsora laricipopulina	72.19	2.00e-58	218.00
IUUC-Mvi-060330	Microbotryum violaceum	73.51	3.00e-59	220.00
IUUC-Mmr-060956	Microcebus murinus	97.37	6.00e-85	305.00
IUUC-Mdo-062292	Monodelphis domestica	99.34	2.00e-88	317.00
IUUC-Mmu-063680	Mus musculus	99.34	2.00e-88	317.00
IUUC-Mac-064774	Musa acuminata	78.52	1.00e-71	261.00
IUUC-Nfi-068580	Neosartorya fischeri	69.54	8.00e-64	235.00
IUUC-Ncr-068913	Neurospora crassa	69.54	2.00e-64	237.00
IUUC-Nle-069121	Nomascus leucogenys	99.34	2.00e-88	317.00
IUUC-Ont-071335	Oreochromis niloticus	97.37	1.00e-86	311.00
IUUC-Ocu-074550	Oryctolagus cuniculus	99.34	4.00e-88	317.00
IUUC-Oba-075896	Oryza barthii	77.85	4.00e-71	259.00
IUUC-Obr-076713	Oryza brachyantha	78.52	1.00e-71	261.00
IUUC-Ogl-077116	Oryza glaberrima	78.52	1.00e-71	261.00
IUUC-Ogu-078696	Oryza glumaepatula	78.52	1.00e-71	261.00
IUUC-Oin-079099	Oryza indica	78.52	1.00e-71	261.00
IUUC-Olo-081018	Oryza longistaminata	66.67	4.00e-62	230.00
IUUC-Ome-081285	Oryza meridionalis	78.52	1.00e-71	261.00
IUUC-Oni-082088	Oryza nivara	78.52	1.00e-71	261.00
IUUC-Opu-083310	Oryza punctata	78.52	1.00e-71	261.00
IUUC-Oru-084449	Oryza rufipogon	78.52	1.00e-71	261.00
IUUC-Osa-085923	Oryza sativa	78.52	1.00e-71	261.00
IUUC-Ola-086407	Oryzias latipes	99.34	2.00e-88	317.00
IUUC-Olu-087830	Ostreococcus lucimarinus	79.19	3.00e-62	230.00
IUUC-Oga-088659	Otolemur garnettii	99.34	2.00e-88	317.00
IUUC-Ptr-091305	Pan troglodytes	99.34	2.00e-88	317.00
IUUC-Pan-092740	Papio anubis	99.34	5.00e-88	317.00
IUUC-Psi-094094	Pelodiscus sinensis	99.34	2.00e-88	317.00
IUUC-Pma-094376	Petromyzon marinus	95.36	2.00e-85	306.00
IUUC-Pno-094935	Phaeosphaeria nodorum	69.54	5.00e-64	236.00
IUUC-Ppa-095689	Physcomitrella patens	78.52	1.00e-62	231.00
IUUC-Pfo-096656	Poecilia formosa	98.68	2.00e-88	317.00
IUUC-Pab-097972	Pongo abelii	99.34	2.00e-88	317.00
IUUC-Pop-099517	Populus trichocarpa	78.52	9.00e-72	261.00
IUUC-Pca-100906	Procavia capensis	92.76	1.00e-80	291.00
IUUC-Ppe-101594	Prunus persica	78.52	2.00e-71	261.00
IUUC-Pva-102380	Pteropus vampyrus	98.03	2.00e-85	307.00
IUUC-Rno-105577	Rattus norvegicus	93.21	3.00e-86	310.00
IUUC-Sja-107790	Schizosaccharomyces japonicus	71.81	9.00e-59	218.00
IUUC-Spo-108073	Schizosaccharomyces pombe	71.81	6.00e-59	219.00
IUUC-Ssl-108432	Sclerotinia sclerotiorum	70.20	7.00e-65	238.00
IUUC-Smo-109512	Selaginella moellendorffii	78.52	5.00e-72	262.00
IUUC-Sit-110731	Setaria italica	78.52	1.00e-71	261.00
IUUC-Sly-111506	Solanum lycopersicum	77.85	2.00e-71	260.00
IUUC-Stu-112080	Solanum tuberosum	77.85	2.00e-71	260.00
IUUC-Sbi-114289	Sorghum bicolor	78.52	1.00e-71	261.00
IUUC-Sre-115106	Sporisorium reilianum	72.85	5.00e-60	223.00
IUUC-Ssc-116265	Sus scrofa	99.34	2.00e-88	317.00
IUUC-Tgu-117383	Taeniopygia guttata	99.34	2.00e-88	317.00
IUUC-Tru-117924	Takifugu rubripes	91.36	3.00e-81	293.00
IUUC-Tni-119743	Tetraodon nigroviridis	96.71	1.00e-84	304.00
IUUC-Tca-121827	Theobroma cacao	79.19	7.00e-72	262.00
IUUC-Tre-122002	Trichoderma reesei	69.54	4.00e-64	236.00
IUUC-Tvi-122331	Trichoderma virens	69.54	4.00e-64	236.00
IUUC-Tae-124461	Triticum aestivum	77.18	4.00e-71	260.00
IUUC-Tur-126866	Triticum urartu	77.18	6.00e-71	258.00
IUUC-Tme-127148	Tuber melanosporum	71.05	1.00e-65	241.00
IUUC-Ttr-129050	Tursiops truncatus	98.68	2.00e-85	307.00
IUUC-Vda-129711	Verticillium dahliae	69.54	2.00e-64	237.00
IUUC-Vvi-131547	Vitis vinifera	78.52	9.00e-72	262.00
IUUC-Xtr-132301	Xenopus tropicalis	99.34	2.00e-88	317.00
IUUC-Xma-133937	Xiphophorus maculatus	99.34	2.00e-88	317.00
IUUC-Zma-135584	Zea mays	76.51	3.00e-70	256.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence