iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037528

Ensembl Protein ID

ENSFALP00000006461.1

UniProt Accession

U3JUK7; U3JUK7_FICAL

Genbank Protein ID

ENSFALP00000006461

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000253

Gene Name

USP14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000006194.1	ENSFALT00000006490.1	ENSFALP00000006461.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-62	210.4	112	485
ULD/UDP/UBQ/UBQ_Other	5.40e-09	35.5	13	81

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pe++e+l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 112  CGLTNLGNTCYMNATVQCIRSVPEVKEALKR-YGGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekgd 198
           7******************************.****************************.99999******************99*** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+           e d+   +d+      +k+ksli++ F +++++ +kc e +++ +++ + + l
   Q: 199  qgQYLQQDANECWVQMMRVLQQKLEG---------IEGDTVMETDSGATAASSKKKSLIDQFFSIEFETVMKCTEAEEEEVTKGKENLL 278
           999*********************55.........444444445667789999*********************999988776666666 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +      +++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 279  QLSCFINQEV--KYLFTGLKLRLQEEITK-----LSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDV 360
           6665555533..47999999999988887.....7899999999********************************************* PP
   S: 262  spfcts........................peekqke...........................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                         p     +                           +  Y+L av+ H+G s+ssGHYv++
   Q: 361  YELCTPdlqekmvsyrskfkdledkkvnqqP-----KnssksdgaqkevkyepfsfpddigsnnCGYYDLQAVLTHQGrSSSSGHYVSW 444
           ******7777777777777777666665551.....0445556666667777777777777777************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 445  VKRKQDEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 485
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v vk+ + +  ++++n +++  ++K +++ ++g++p++q+ ++kG  L+dd +++++++k+g+t++++ +
   Q: 13   VNVKWGKEKFDGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDD-DWGNLKIKNGMTLLMMGS 81
           6799999998899***********************************999.9**************965 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MVLWDIFGPA GSVNVKWGKE KFDGVELNTD EPPMVFKAQL FALTGVQPAR QKVMVKGGTL 60
KDDDWGNLKI KNGMTLLMMG SADALPEEPI ARPVFVEDMT EEQLASAMEL PCGLTNLGNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCAGAGTT CCTCAGTGTA TGTTACTTCC ATGGTTTTGT GGGATATTTT TGGACCTGCT 60
GGAAGCGGTA TGTTCTGATG GATGAGGTGC CGTACAGTAA AGGCATTCCC TGGCTTCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fab:101822173

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	43.96	2.00e-38	153.00
IUUC-Aml-002053	Ailuropoda melanoleuca	90.82	0.00e+00	879.00
IUUC-Atr-002725	Amborella trichopoda	41.88	2.00e-101	362.00
IUUC-Apl-004031	Anas platyrhynchos	98.36	0.00e+00	957.00
IUUC-Aca-004361	Anolis carolinensis	92.91	0.00e+00	944.00
IUUC-Aly-006176	Arabidopsis lyrata	42.39	2.00e-111	395.00
IUUC-Ath-007658	Arabidopsis thaliana	41.60	4.00e-111	395.00
IUUC-Ago-007796	Ashbya gossypii	32.77	1.00e-57	217.00
IUUC-Acl-008258	Aspergillus clavatus	38.76	2.00e-66	246.00
IUUC-Afl-008732	Aspergillus flavus	35.12	5.00e-82	298.00
IUUC-Afu-008755	Aspergillus fumigatus	35.46	4.00e-83	301.00
IUUC-Ani-009148	Aspergillus nidulans	39.36	1.00e-70	260.00
IUUC-Ang-009878	Aspergillus niger	35.10	2.00e-78	286.00
IUUC-Aor-010239	Aspergillus oryzae	35.12	4.00e-82	298.00
IUUC-Ate-010243	Aspergillus terreus	35.26	2.00e-80	292.00
IUUC-Ame-011327	Astyanax mexicanus	52.02	7.00e-127	447.00
IUUC-Bgr-012231	Blumeria graminis	34.15	1.00e-77	283.00
IUUC-Bta-012553	Bos taurus	90.47	0.00e+00	888.00
IUUC-Bci-013606	Botrytis cinerea	39.58	2.00e-70	259.00
IUUC-Bdi-014567	Brachypodium distachyon	43.24	7.00e-114	403.00
IUUC-Bol-015565	Brassica oleracea	41.85	1.00e-111	396.00
IUUC-Bra-017297	Brassica rapa	41.88	1.00e-111	396.00
IUUC-Cel-018140	Caenorhabditis elegans	41.43	4.00e-101	361.00
IUUC-Cja-019516	Callithrix jacchus	89.90	0.00e+00	892.00
IUUC-Cfa-020808	Canis familiaris	91.48	0.00e+00	898.00
IUUC-Cpo-021688	Cavia porcellus	90.43	0.00e+00	883.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	38.65	9.00e-85	306.00
IUUC-Csa-023429	Chlorocebus sabaeus	90.65	0.00e+00	873.00
IUUC-Cho-024347	Choloepus hoffmanni	89.74	0.00e+00	890.00
IUUC-Cin-025198	Ciona intestinalis	54.90	5.00e-152	530.00
IUUC-Csv-026007	Ciona savignyi	53.33	9.00e-152	529.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	39.30	1.00e-63	237.00
IUUC-Cne-026963	Cryptococcus neoformans	35.50	4.00e-76	278.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.93	5.00e-59	221.00
IUUC-Dre-027647	Danio rerio	83.81	0.00e+00	841.00
IUUC-Dno-029967	Dasypus novemcinctus	89.66	0.00e+00	874.00
IUUC-Dor-030886	Dipodomys ordii	84.55	0.00e+00	714.00
IUUC-Dse-031466	Dothistroma septosporum	36.29	2.00e-58	219.00
IUUC-Dme-032079	Drosophila melanogaster	54.87	3.00e-156	544.00
IUUC-Ete-032351	Echinops telfairi	81.87	0.00e+00	814.00
IUUC-Eca-033461	Equus caballus	90.41	0.00e+00	929.00
IUUC-Eeu-035220	Erinaceus europaeus	68.72	0.00e+00	640.00
IUUC-Fca-036210	Felis catus	91.28	0.00e+00	897.00
IUUC-Fox-037805	Fusarium oxysporum	41.10	9.00e-72	264.00
IUUC-Fso-038177	Fusarium solani	39.16	1.00e-67	250.00
IUUC-Gmo-038953	Gadus morhua	77.51	0.00e+00	765.00
IUUC-Ggr-039972	Gaeumannomyces graminis	35.77	1.00e-75	277.00
IUUC-Gga-040462	Gallus gallus	96.54	0.00e+00	941.00
IUUC-Gac-041312	Gasterosteus aculeatus	79.88	0.00e+00	801.00
IUUC-Gma-043255	Glycine max	42.42	1.00e-106	379.00
IUUC-Ggo-045458	Gorilla gorilla	75.46	0.00e+00	728.00
IUUC-Hsa-045706	Homo sapiens	90.87	0.00e+00	876.00
IUUC-Hvu-047821	Hordeum vulgare	48.11	2.00e-57	215.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	88.64	0.00e+00	895.00
IUUC-Lch-050464	Latimeria chalumnae	83.95	0.00e+00	834.00
IUUC-Lpe-051419	Leersia perrieri	41.88	3.00e-108	385.00
IUUC-Loc-052732	Lepisosteus oculatus	81.95	0.00e+00	853.00
IUUC-Lma-053177	Leptosphaeria maculans	42.05	2.00e-71	263.00
IUUC-Laf-053822	Loxodonta africana	91.21	0.00e+00	889.00
IUUC-Mcc-055893	Macaca mulatta	90.85	0.00e+00	874.00
IUUC-Meu-056307	Macropus eugenii	81.43	0.00e+00	793.00
IUUC-Mor-057171	Magnaporthe oryzae	40.26	1.00e-67	250.00
IUUC-Mpo-057415	Magnaporthe poae	41.91	1.00e-71	263.00
IUUC-Mtr-057901	Medicago truncatula	42.91	3.00e-110	392.00
IUUC-Mla-058897	Melampsora laricipopulina	40.74	2.00e-75	276.00
IUUC-Mga-060016	Meleagris gallopavo	97.54	0.00e+00	950.00
IUUC-Mvi-060562	Microbotryum violaceum	40.00	2.00e-67	249.00
IUUC-Mmr-060624	Microcebus murinus	90.47	0.00e+00	929.00
IUUC-Mdo-061809	Monodelphis domestica	92.73	0.00e+00	900.00
IUUC-Mmu-063869	Mus musculus	89.25	0.00e+00	877.00
IUUC-Mac-064876	Musa acuminata	39.35	3.00e-96	345.00
IUUC-Mpu-066480	Mustela putorius furo	91.08	0.00e+00	894.00
IUUC-Mlu-067866	Myotis lucifugus	90.00	0.00e+00	895.00
IUUC-Nfi-068393	Neosartorya fischeri	35.04	6.00e-77	281.00
IUUC-Ncr-068815	Neurospora crassa	37.05	2.00e-80	293.00
IUUC-Nle-070121	Nomascus leucogenys	89.33	4.00e-129	453.00
IUUC-Opr-070712	Ochotona princeps	72.66	6.00e-164	570.00
IUUC-Ont-071544	Oreochromis niloticus	81.39	0.00e+00	767.00
IUUC-Oan-073635	Ornithorhynchus anatinus	91.80	0.00e+00	760.00
IUUC-Ocu-074926	Oryctolagus cuniculus	90.45	0.00e+00	870.00
IUUC-Oba-075633	Oryza barthii	41.58	7.00e-108	384.00
IUUC-Obr-076423	Oryza brachyantha	42.74	4.00e-111	394.00
IUUC-Ogl-077913	Oryza glaberrima	41.46	1.00e-110	392.00
IUUC-Ogu-078435	Oryza glumaepatula	41.58	7.00e-108	384.00
IUUC-Oin-080072	Oryza indica	41.58	6.00e-108	384.00
IUUC-Olo-080535	Oryza longistaminata	39.23	2.00e-93	335.00
IUUC-Ome-081309	Oryza meridionalis	41.58	7.00e-108	384.00
IUUC-Oni-083113	Oryza nivara	41.58	7.00e-108	384.00
IUUC-Opu-083168	Oryza punctata	40.42	3.00e-102	365.00
IUUC-Oru-084253	Oryza rufipogon	41.58	7.00e-108	384.00
IUUC-Osa-085554	Oryza sativa	41.46	8.00e-111	393.00
IUUC-Ola-086998	Oryzias latipes	80.45	0.00e+00	793.00
IUUC-Olu-087818	Ostreococcus lucimarinus	37.10	1.00e-70	260.00
IUUC-Oga-088571	Otolemur garnettii	90.85	0.00e+00	894.00
IUUC-Oar-089526	Ovis aries	90.82	0.00e+00	887.00
IUUC-Ptr-091433	Pan troglodytes	90.85	0.00e+00	874.00
IUUC-Pan-091966	Papio anubis	90.65	0.00e+00	873.00
IUUC-Psi-093458	Pelodiscus sinensis	93.29	0.00e+00	887.00
IUUC-Pma-094343	Petromyzon marinus	68.64	1.00e-118	419.00
IUUC-Pno-095109	Phaeosphaeria nodorum	40.58	1.00e-66	247.00
IUUC-Ppa-095756	Physcomitrella patens	42.26	3.00e-111	395.00
IUUC-Pfo-096514	Poecilia formosa	82.62	0.00e+00	788.00
IUUC-Pab-098477	Pongo abelii	79.57	0.00e+00	697.00
IUUC-Pop-099221	Populus trichocarpa	41.97	4.00e-104	371.00
IUUC-Pca-100791	Procavia capensis	73.89	6.00e-164	569.00
IUUC-Ppe-101812	Prunus persica	41.75	8.00e-108	383.00
IUUC-Pva-102462	Pteropus vampyrus	85.55	0.00e+00	719.00
IUUC-Pgr-103623	Puccinia graminis	42.29	8.00e-77	281.00
IUUC-Ptt-103767	Puccinia triticina	40.24	2.00e-68	253.00
IUUC-Pte-104109	Pyrenophora teres	40.63	2.00e-71	263.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	41.02	2.00e-71	263.00
IUUC-Rno-105351	Rattus norvegicus	88.03	0.00e+00	848.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.73	6.00e-61	228.00
IUUC-Sha-107491	Sarcophilus harrisii	92.51	0.00e+00	914.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	35.13	1.00e-79	290.00
IUUC-Spo-108174	Schizosaccharomyces pombe	36.88	3.00e-79	288.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	35.44	4.00e-84	305.00
IUUC-Smo-109276	Selaginella moellendorffii	43.48	4.00e-110	391.00
IUUC-Sit-110361	Setaria italica	43.32	2.00e-114	405.00
IUUC-Sly-110965	Solanum lycopersicum	41.65	6.00e-109	387.00
IUUC-Sar-113355	Sorex araneus	79.39	0.00e+00	634.00
IUUC-Sbi-114778	Sorghum bicolor	43.76	1.00e-112	399.00
IUUC-Sre-115011	Sporisorium reilianum	36.83	3.00e-63	236.00
IUUC-Ssc-116273	Sus scrofa	90.59	0.00e+00	877.00
IUUC-Tgu-117063	Taeniopygia guttata	98.98	0.00e+00	942.00
IUUC-Tru-118381	Takifugu rubripes	80.49	0.00e+00	798.00
IUUC-Tsy-119076	Tarsius syrichta	75.89	4.00e-111	394.00
IUUC-Tni-119941	Tetraodon nigroviridis	80.94	0.00e+00	788.00
IUUC-Tca-121246	Theobroma cacao	42.37	1.00e-108	386.00
IUUC-Tre-121969	Trichoderma reesei	38.40	1.00e-65	243.00
IUUC-Tvi-122543	Trichoderma virens	32.98	9.00e-68	251.00
IUUC-Tae-125484	Triticum aestivum	43.15	5.00e-110	390.00
IUUC-Tur-126128	Triticum urartu	32.28	4.00e-67	248.00
IUUC-Tbe-128030	Tupaia belangeri	84.02	0.00e+00	797.00
IUUC-Ttr-128701	Tursiops truncatus	89.86	0.00e+00	730.00
IUUC-Uma-129657	Ustilago maydis	36.44	1.00e-65	243.00
IUUC-Vda-129723	Verticillium dahliae	36.50	6.00e-59	221.00
IUUC-Vpa-130284	Vicugna pacos	64.75	5.00e-169	587.00
IUUC-Vvi-131037	Vitis vinifera	43.93	7.00e-112	397.00
IUUC-Xtr-132235	Xenopus tropicalis	87.25	0.00e+00	892.00
IUUC-Xma-133840	Xiphophorus maculatus	82.62	0.00e+00	813.00
IUUC-Yli-134453	Yarrowia lipolytica	36.87	4.00e-82	298.00
IUUC-Zma-135669	Zea mays	36.73	3.00e-95	342.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence