iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045458

UUCD1 version

UUC-GoG-01136

Ensembl Protein ID

ENSGGOP00000025208.1

UniProt Accession

G3SAT5; G3SAT5_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000003003.2	ENSGGOT00000003023.2	ENSGGOP00000002957.2
ENSGGOG00000003003.2	ENSGGOT00000033383.1	ENSGGOP00000025208.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.00e-47	160.5	106	481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+++l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 106  CGLTNLGNTCYMNATVQCIRSVPELKDALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekge 192
           7******************************.****************************.99999******************999*9 PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk...sqikclecdnvssreepf 169
             +y qqDa+E++ +++  l+++l+  ++ +++e+        s++a+  +++k+ksli++ F+++++   +++kc e +++ +++ + 
   Q: 193  qgQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETD-------SSSASVATPSKKKSLIDQFFGVEFEttlQSMKCTESEEEEVTKGKE 274
           999*********************664444444443.......334788999*************999555667799999999999999 PP
   S: 170  ldlslpvpgkeetkke..........................slqdcLesftkeeelegenkyycekckkkqe............aekk 220
           ++l+l+   ++e k +                          s+ d+ +  ++ e +     ++ ++c++ ++            a   
   Q: 275  NQLQLSCFINQEVKYLftglklvrtisqksnklqlalhfidkSIIDMVAYDFSLEIVV----FNYSSCDSTSKaliirirkplypA--- 356
           999888888887777789********************99998888888888888887....555555555554456544333332... PP
   S: 221  lklkklPev....Lilh....LkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayv 299
             +k+l+ v    L +     Lk ++f+   +++++ ++k + p++ ++ +pf   ++ +++++  Y+L av+ H+G s+ssGHYv++v
   Q: 357  --FKELCAVfldkLFFSckslLKNIEFKF--YFQNHDSDKKSSPQKeVKYEPFSFADDIGSNNCGYYDLQAVLTHQGrSSSSGHYVSWV 441
           ..333333200002222011144445544..34444444455566669999999999999999************************** PP
   S: 300  knekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           k ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 442  KRKQDEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 481
           *************************988************ PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

VILFAVTVKW GKEKFEGVEL NTDEPPMVFK AQLFALTGVQ PARQKVMVKG GTLKSDKSGH 60
IKVKKQGMTL LMMGSADALP EEPSAKTVFV EDMTEEQLAS AMELPCGLTN LGNTCYMNAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGTCTCCT CGCTGCAGTC GCTCCGGAGC TGCACGGGTG TTCTGCGTGT TGCTGCGTCA 60
TCGCCAGTGG CCGGTTTGAA TGAGACTCGT CGCACCGAAG CCGCCGCCAC CACCGCGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0009986--C:cell surface
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045202--C:synapse
GO:0004866--F:endopeptidase inhibitor activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007268--P:chemical synaptic transmission
GO:1903070--P:negative regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0016579--P:protein deubiquitination
GO:0050920--P:regulation of chemotaxis
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	32.28	5.00e-61	228.00
IUUC-Aml-002053	Ailuropoda melanoleuca	79.48	0.00e+00	740.00
IUUC-Atr-002725	Amborella trichopoda	36.85	1.00e-76	280.00
IUUC-Apl-004031	Anas platyrhynchos	73.24	0.00e+00	712.00
IUUC-Aca-004361	Anolis carolinensis	74.80	0.00e+00	723.00
IUUC-Aly-006078	Arabidopsis lyrata	37.18	2.00e-84	306.00
IUUC-Ath-007658	Arabidopsis thaliana	37.60	2.00e-85	309.00
IUUC-Ago-007796	Ashbya gossypii	28.86	4.00e-38	152.00
IUUC-Acl-008258	Aspergillus clavatus	31.87	7.00e-39	155.00
IUUC-Afl-008732	Aspergillus flavus	33.33	6.00e-41	162.00
IUUC-Afu-008755	Aspergillus fumigatus	32.27	9.00e-42	164.00
IUUC-Ani-009148	Aspergillus nidulans	33.67	2.00e-45	176.00
IUUC-Ang-009878	Aspergillus niger	34.38	8.00e-42	164.00
IUUC-Aor-010239	Aspergillus oryzae	33.33	7.00e-41	161.00
IUUC-Ate-010243	Aspergillus terreus	33.08	1.00e-37	150.00
IUUC-Ame-011327	Astyanax mexicanus	54.47	3.00e-71	262.00
IUUC-Bgr-012231	Blumeria graminis	30.73	6.00e-56	211.00
IUUC-Bta-012553	Bos taurus	77.98	0.00e+00	751.00
IUUC-Bci-013606	Botrytis cinerea	34.35	2.00e-45	176.00
IUUC-Bdi-014567	Brachypodium distachyon	38.26	2.00e-84	306.00
IUUC-Bol-015565	Brassica oleracea	36.90	1.00e-85	310.00
IUUC-Bra-017297	Brassica rapa	36.76	3.00e-85	308.00
IUUC-Cel-018140	Caenorhabditis elegans	33.86	2.00e-68	252.00
IUUC-Cja-019516	Callithrix jacchus	83.20	0.00e+00	783.00
IUUC-Cfa-020808	Canis familiaris	81.62	0.00e+00	764.00
IUUC-Cpo-021688	Cavia porcellus	78.76	0.00e+00	757.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	35.38	7.00e-59	221.00
IUUC-Csa-023429	Chlorocebus sabaeus	79.80	0.00e+00	741.00
IUUC-Cho-024347	Choloepus hoffmanni	78.18	0.00e+00	758.00
IUUC-Cin-025198	Ciona intestinalis	45.73	9.00e-115	407.00
IUUC-Csv-026007	Ciona savignyi	44.18	2.00e-116	412.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	34.56	4.00e-41	162.00
IUUC-Cne-026963	Cryptococcus neoformans	31.79	2.00e-56	213.00
IUUC-Cme-027240	Cyanidioschyzon merolae	26.89	5.00e-43	168.00
IUUC-Dre-027647	Danio rerio	69.11	0.00e+00	666.00
IUUC-Dno-029967	Dasypus novemcinctus	78.38	0.00e+00	733.00
IUUC-Dor-030886	Dipodomys ordii	71.27	7.00e-164	570.00
IUUC-Dse-031466	Dothistroma septosporum	32.30	6.00e-35	142.00
IUUC-Dme-032079	Drosophila melanogaster	46.94	1.00e-120	426.00
IUUC-Ete-032351	Echinops telfairi	64.50	2.00e-173	602.00
IUUC-Eca-033461	Equus caballus	81.69	0.00e+00	809.00
IUUC-Eeu-035220	Erinaceus europaeus	64.96	8.00e-172	596.00
IUUC-Fca-036210	Felis catus	79.60	0.00e+00	766.00
IUUC-Fal-037528	Ficedula albicollis	72.41	0.00e+00	685.00
IUUC-Fox-037805	Fusarium oxysporum	33.25	8.00e-43	168.00
IUUC-Fso-038177	Fusarium solani	35.02	6.00e-42	165.00
IUUC-Gmo-038953	Gadus morhua	65.45	4.00e-176	610.00
IUUC-Ggr-039972	Gaeumannomyces graminis	32.10	9.00e-42	164.00
IUUC-Gga-040462	Gallus gallus	72.73	0.00e+00	698.00
IUUC-Gac-041312	Gasterosteus aculeatus	68.03	0.00e+00	639.00
IUUC-Gma-043255	Glycine max	38.81	5.00e-84	304.00
IUUC-Hsa-045706	Homo sapiens	79.80	0.00e+00	741.00
IUUC-Hvu-047821	Hordeum vulgare	45.37	1.00e-54	206.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	81.01	0.00e+00	756.00
IUUC-Lch-050464	Latimeria chalumnae	69.15	0.00e+00	662.00
IUUC-Lpe-051419	Leersia perrieri	37.47	8.00e-84	303.00
IUUC-Loc-052732	Lepisosteus oculatus	68.42	0.00e+00	681.00
IUUC-Lma-053177	Leptosphaeria maculans	37.43	2.00e-49	190.00
IUUC-Laf-053822	Loxodonta africana	79.07	0.00e+00	765.00
IUUC-Mcc-055893	Macaca mulatta	79.80	0.00e+00	741.00
IUUC-Meu-056307	Macropus eugenii	65.45	9.00e-174	603.00
IUUC-Mor-057171	Magnaporthe oryzae	36.29	2.00e-46	180.00
IUUC-Mpo-057415	Magnaporthe poae	34.91	7.00e-46	178.00
IUUC-Mtr-057901	Medicago truncatula	38.43	4.00e-85	308.00
IUUC-Mla-058897	Melampsora laricipopulina	33.24	2.00e-51	197.00
IUUC-Mga-060016	Meleagris gallopavo	72.84	0.00e+00	708.00
IUUC-Mvi-060562	Microbotryum violaceum	33.07	2.00e-43	170.00
IUUC-Mmr-060624	Microcebus murinus	81.01	0.00e+00	801.00
IUUC-Mdo-061809	Monodelphis domestica	74.40	0.00e+00	701.00
IUUC-Mmu-063869	Mus musculus	77.13	0.00e+00	751.00
IUUC-Mac-064876	Musa acuminata	36.62	2.00e-76	279.00
IUUC-Mpu-066480	Mustela putorius furo	78.99	0.00e+00	762.00
IUUC-Mlu-067866	Myotis lucifugus	80.68	0.00e+00	773.00
IUUC-Nfi-068393	Neosartorya fischeri	31.77	4.00e-40	159.00
IUUC-Ncr-068815	Neurospora crassa	33.33	3.00e-46	179.00
IUUC-Nle-070121	Nomascus leucogenys	96.03	9.00e-134	469.00
IUUC-Opr-070712	Ochotona princeps	57.21	2.00e-123	436.00
IUUC-Ont-071544	Oreochromis niloticus	68.15	1.00e-175	609.00
IUUC-Oan-073635	Ornithorhynchus anatinus	72.09	4.00e-166	577.00
IUUC-Ocu-074926	Oryctolagus cuniculus	78.18	0.00e+00	729.00
IUUC-Oba-075633	Oryza barthii	36.65	1.00e-83	303.00
IUUC-Obr-076423	Oryza brachyantha	37.25	6.00e-85	308.00
IUUC-Ogl-077913	Oryza glaberrima	36.08	3.00e-83	302.00
IUUC-Ogu-078435	Oryza glumaepatula	36.65	1.00e-83	303.00
IUUC-Oin-080072	Oryza indica	36.70	1.00e-83	303.00
IUUC-Olo-080535	Oryza longistaminata	34.60	6.00e-68	251.00
IUUC-Ome-081309	Oryza meridionalis	36.65	1.00e-83	303.00
IUUC-Oni-083113	Oryza nivara	36.65	1.00e-83	303.00
IUUC-Opu-083168	Oryza punctata	36.23	2.00e-81	295.00
IUUC-Oru-084253	Oryza rufipogon	36.65	1.00e-83	303.00
IUUC-Osa-085554	Oryza sativa	36.47	4.00e-83	301.00
IUUC-Ola-086998	Oryzias latipes	67.68	0.00e+00	635.00
IUUC-Olu-087818	Ostreococcus lucimarinus	32.66	3.00e-52	199.00
IUUC-Oga-088571	Otolemur garnettii	78.38	0.00e+00	753.00
IUUC-Oar-089526	Ovis aries	78.59	0.00e+00	756.00
IUUC-Ptr-091433	Pan troglodytes	79.80	0.00e+00	741.00
IUUC-Pan-091966	Papio anubis	79.80	0.00e+00	741.00
IUUC-Psi-093458	Pelodiscus sinensis	73.35	0.00e+00	663.00
IUUC-Pma-094343	Petromyzon marinus	66.78	7.00e-115	406.00
IUUC-Pno-095109	Phaeosphaeria nodorum	35.07	9.00e-44	171.00
IUUC-Ppa-095756	Physcomitrella patens	38.82	2.00e-86	312.00
IUUC-Pfo-096514	Poecilia formosa	68.36	2.00e-179	621.00
IUUC-Pab-098477	Pongo abelii	70.89	3.00e-164	571.00
IUUC-Pop-099221	Populus trichocarpa	36.45	1.00e-77	283.00
IUUC-Pca-100791	Procavia capensis	70.30	4.00e-151	527.00
IUUC-Ppe-101812	Prunus persica	36.53	3.00e-81	295.00
IUUC-Pva-102462	Pteropus vampyrus	75.41	1.00e-173	602.00
IUUC-Pgr-103623	Puccinia graminis	35.45	2.00e-55	209.00
IUUC-Ptt-103767	Puccinia triticina	33.64	3.00e-45	176.00
IUUC-Pte-104109	Pyrenophora teres	34.85	6.00e-48	185.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	36.14	3.00e-49	189.00
IUUC-Rno-105351	Rattus norvegicus	77.13	0.00e+00	709.00
IUUC-Sce-106168	Saccharomyces cerevisiae	30.88	8.00e-29	121.00
IUUC-Sha-107491	Sarcophilus harrisii	74.75	0.00e+00	720.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	29.22	3.00e-56	212.00
IUUC-Spo-108174	Schizosaccharomyces pombe	31.90	5.00e-55	208.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	33.98	6.00e-44	172.00
IUUC-Smo-108805	Selaginella moellendorffii	39.43	1.00e-83	303.00
IUUC-Sit-110361	Setaria italica	37.84	7.00e-87	314.00
IUUC-Sly-110965	Solanum lycopersicum	35.55	8.00e-81	294.00
IUUC-Sar-113355	Sorex araneus	75.47	3.00e-116	411.00
IUUC-Sbi-114778	Sorghum bicolor	38.79	5.00e-86	311.00
IUUC-Sre-115011	Sporisorium reilianum	31.90	4.00e-42	165.00
IUUC-Ssc-116273	Sus scrofa	79.80	0.00e+00	761.00
IUUC-Tgu-117063	Taeniopygia guttata	71.92	0.00e+00	685.00
IUUC-Tru-118381	Takifugu rubripes	66.60	0.00e+00	630.00
IUUC-Tsy-119076	Tarsius syrichta	61.40	3.00e-76	278.00
IUUC-Tni-119941	Tetraodon nigroviridis	67.28	0.00e+00	628.00
IUUC-Tca-121246	Theobroma cacao	36.76	1.00e-82	300.00
IUUC-Tre-121969	Trichoderma reesei	37.25	1.00e-44	174.00
IUUC-Tvi-122543	Trichoderma virens	34.26	2.00e-39	156.00
IUUC-Tae-125744	Triticum aestivum	37.37	1.00e-82	300.00
IUUC-Tur-126128	Triticum urartu	43.35	3.00e-41	162.00
IUUC-Tbe-128030	Tupaia belangeri	71.49	0.00e+00	662.00
IUUC-Ttr-128701	Tursiops truncatus	78.87	4.00e-174	603.00
IUUC-Uma-129657	Ustilago maydis	33.04	6.00e-45	175.00
IUUC-Vda-129723	Verticillium dahliae	32.89	3.00e-38	153.00
IUUC-Vpa-130284	Vicugna pacos	62.17	7.00e-156	543.00
IUUC-Vvi-131037	Vitis vinifera	38.00	1.00e-81	296.00
IUUC-Xtr-132235	Xenopus tropicalis	72.47	0.00e+00	710.00
IUUC-Xma-133840	Xiphophorus maculatus	68.36	0.00e+00	646.00
IUUC-Yli-134453	Yarrowia lipolytica	32.42	1.00e-60	226.00
IUUC-Zma-135669	Zea mays	33.81	1.00e-77	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence