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Tag Content
iUUCD ID IUUC-Ont-071682
Ensembl Protein ID ENSONIP00000015811.1
UniProt Accession I3K3W6; I3K3W6_ORENI
Genbank Protein ID ENSONIP00000015811
Protein Name Nitric oxide synthase-interacting protein
Genbank Nucleotide ID AERX01058295
Gene Name nosip
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSONIG00000012559.1 ENSONIT00000015825.1 ENSONIP00000015810.1
ENSONIG00000012559.1 ENSONIT00000015826.1 ENSONIP00000015811.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 2.20e-15 56.9 40 81
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktc 43
           v ++ +C +sl++ rdPvv+p+G+ y++++I +++ +++++ 
   Q: 40   VKDFDCCCLSLQPCRDPVVTPDGYLYEKQAILEYILHQKTQI 81
           567789*****************************9998833 PP
   
Organism Oreochromis niloticus
Functional Description
(View)

Functional Description


     Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
 Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
Protein Sequence
(Fasta)
MTRHGKNCTA GAVYTYHEKK KDTAASGYGT QSVRLGRDAV KDFDCCCLSL QPCRDPVVTP 60
DGYLYEKQAI LEYILHQKTQ IAKKMKAYEK QKQAQRSSNQ LESKSEERER VERFKTKENS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ont-071682|E3,U-box|Oreochromis niloticus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGTCACTCAC CAGTGTTCGA GTAACGTGGA GAAGAAGAAG AACAAAACGA AATACAACGA 60
CGAAGAAGAG CGTGTGGCTG TAGTCTGCGT TAAGAAAAGA TTGTTCCGGA ATATAATTTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ont-071682|E3,U-box|Oreochromis niloticus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD
Pfam

PF15906--zf-NOSIP
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0050999--P:regulation of nitric-oxide synthase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000769 Aegilops tauschii 45.35 7.00e-16 79.00
IUUC-Aml-002069 Ailuropoda melanoleuca 64.54 1.00e-114 405.00
IUUC-Atr-002661 Amborella trichopoda 28.43 2.00e-27 116.00
IUUC-Aca-004630 Anolis carolinensis 66.56 2.00e-117 415.00
IUUC-Aly-006316 Arabidopsis lyrata 28.62 2.00e-30 126.00
IUUC-Ath-007000 Arabidopsis thaliana 28.62 2.00e-30 125.00
IUUC-Acl-008175 Aspergillus clavatus 33.33 6.00e-07 48.50
IUUC-Afl-008440 Aspergillus flavus 25.40 4.00e-10 58.90
IUUC-Afu-009012 Aspergillus fumigatus 30.65 4.00e-07 49.30
IUUC-Ani-009153 Aspergillus nidulans 30.08 5.00e-04 38.90
IUUC-Ang-009556 Aspergillus niger 24.36 2.00e-11 63.50
IUUC-Aor-009892 Aspergillus oryzae 23.79 1.00e-08 54.30
IUUC-Ame-011874 Astyanax mexicanus 79.74 2.00e-127 448.00
IUUC-Bgr-012090 Blumeria graminis 25.35 6.00e-06 45.10
IUUC-Bta-012956 Bos taurus 66.67 5.00e-119 420.00
IUUC-Bci-013897 Botrytis cinerea 37.50 2.00e-08 53.50
IUUC-Bdi-014968 Brachypodium distachyon 29.29 7.00e-34 137.00
IUUC-Bol-015578 Brassica oleracea 29.64 6.00e-32 131.00
IUUC-Bra-017234 Brassica rapa 29.64 6.00e-32 131.00
IUUC-Cel-018637 Caenorhabditis elegans 45.25 2.00e-57 215.00
IUUC-Cja-019632 Callithrix jacchus 66.23 3.00e-120 424.00
IUUC-Cfa-020192 Canis familiaris 66.56 8.00e-119 420.00
IUUC-Cpo-021939 Cavia porcellus 66.23 7.00e-119 420.00
IUUC-Cre-023005 Chlamydomonas reinhardtii 32.24 8.00e-37 147.00
IUUC-Csa-023802 Chlorocebus sabaeus 65.89 8.00e-120 423.00
IUUC-Cho-024637 Choloepus hoffmanni 52.20 1.00e-42 166.00
IUUC-Cin-025180 Ciona intestinalis 52.94 5.00e-88 317.00
IUUC-Csv-026206 Ciona savignyi 58.04 1.00e-45 175.00
IUUC-Cgl-026696 Colletotrichum gloeosporioides 23.55 6.00e-12 65.10
IUUC-Cne-026827 Cryptococcus neoformans 25.65 2.00e-08 53.50
IUUC-Dre-028092 Danio rerio 80.46 2.00e-135 474.00
IUUC-Dno-029501 Dasypus novemcinctus 61.31 1.00e-102 367.00
IUUC-Dor-030542 Dipodomys ordii 65.89 7.00e-120 423.00
IUUC-Dse-031188 Dothistroma septosporum 24.31 1.00e-14 73.90
IUUC-Dme-031734 Drosophila melanogaster 47.54 2.00e-81 295.00
IUUC-Eca-033577 Equus caballus 66.89 1.00e-120 425.00
IUUC-Fca-035761 Felis catus 66.56 2.00e-118 418.00
IUUC-Fox-037703 Fusarium oxysporum 25.36 4.00e-13 68.90
IUUC-Fso-038208 Fusarium solani 24.79 1.00e-13 70.50
IUUC-Gmo-038523 Gadus morhua 71.35 3.00e-73 267.00
IUUC-Ggr-040087 Gaeumannomyces graminis 29.50 1.00e-08 53.90
IUUC-Gac-042621 Gasterosteus aculeatus 77.12 2.00e-128 451.00
IUUC-Gma-042698 Glycine max 29.10 5.00e-31 128.00
IUUC-Ggo-045357 Gorilla gorilla 66.23 2.00e-120 425.00
IUUC-Hsa-046195 Homo sapiens 66.23 2.00e-120 425.00
IUUC-Hvu-047174 Hordeum vulgare 29.29 2.00e-33 135.00
IUUC-Itr-048487 Ictidomys tridecemlineatus 66.56 6.00e-118 417.00
IUUC-Lch-050569 Latimeria chalumnae 66.13 1.00e-108 385.00
IUUC-Lpe-050992 Leersia perrieri 32.35 4.00e-22 99.40
IUUC-Loc-052522 Lepisosteus oculatus 74.83 2.00e-120 425.00
IUUC-Lma-053254 Leptosphaeria maculans 24.16 6.00e-08 52.00
IUUC-Laf-053397 Loxodonta africana 65.56 7.00e-118 416.00
IUUC-Mcc-054681 Macaca mulatta 66.56 1.00e-120 426.00
IUUC-Meu-056723 Macropus eugenii 65.56 2.00e-118 418.00
IUUC-Mor-056961 Magnaporthe oryzae 29.46 6.00e-09 55.10
IUUC-Mpo-057359 Magnaporthe poae 21.31 8.00e-06 44.30
IUUC-Mtr-058063 Medicago truncatula 29.43 9.00e-34 137.00
IUUC-Mla-059004 Melampsora laricipopulina 28.97 1.00e-21 97.10
IUUC-Mvi-060460 Microbotryum violaceum 30.51 1.00e-25 110.00
IUUC-Mmr-060847 Microcebus murinus 66.56 5.00e-121 427.00
IUUC-Mdo-062480 Monodelphis domestica 65.46 1.00e-118 419.00
IUUC-Mmu-063809 Mus musculus 65.23 1.00e-117 416.00
IUUC-Mac-064870 Musa acuminata 29.77 1.00e-34 140.00
IUUC-Mpu-066322 Mustela putorius furo 65.03 5.00e-119 421.00
IUUC-Mlu-067556 Myotis lucifugus 66.23 7.00e-119 420.00
IUUC-Nfi-068440 Neosartorya fischeri 24.23 3.00e-09 56.20
IUUC-Ncr-068898 Neurospora crassa 33.33 4.00e-06 45.80
IUUC-Nle-070049 Nomascus leucogenys 66.23 3.00e-120 424.00
IUUC-Opr-070972 Ochotona princeps 65.23 4.00e-119 421.00
IUUC-Oan-073296 Ornithorhynchus anatinus 94.92 1.00e-30 125.00
IUUC-Ocu-074218 Oryctolagus cuniculus 66.43 5.00e-105 374.00
IUUC-Oba-075284 Oryza barthii 28.96 9.00e-32 130.00
IUUC-Obr-076651 Oryza brachyantha 28.76 2.00e-34 139.00
IUUC-Ogl-077899 Oryza glaberrima 28.96 9.00e-32 130.00
IUUC-Ogu-078477 Oryza glumaepatula 29.29 4.00e-32 132.00
IUUC-Oin-080011 Oryza indica 28.96 8.00e-32 130.00
IUUC-Olo-080545 Oryza longistaminata 28.96 4.00e-25 109.00
IUUC-Ome-081543 Oryza meridionalis 28.96 8.00e-32 130.00
IUUC-Oni-082955 Oryza nivara 28.96 8.00e-32 130.00
IUUC-Opu-083565 Oryza punctata 28.96 5.00e-32 131.00
IUUC-Oru-084474 Oryza rufipogon 28.96 8.00e-32 130.00
IUUC-Osa-085913 Oryza sativa 28.96 8.00e-32 130.00
IUUC-Ola-086851 Oryzias latipes 80.79 7.00e-144 503.00
IUUC-Olu-087724 Ostreococcus lucimarinus 29.13 3.00e-10 59.30
IUUC-Oga-087970 Otolemur garnettii 67.00 6.00e-120 423.00
IUUC-Oar-089756 Ovis aries 65.02 2.00e-112 398.00
IUUC-Ptr-091485 Pan troglodytes 65.23 5.00e-117 413.00
IUUC-Pan-091832 Papio anubis 66.23 2.00e-120 425.00
IUUC-Pma-094551 Petromyzon marinus 61.44 5.00e-104 370.00
IUUC-Ppa-095255 Physcomitrella patens 28.67 3.00e-29 122.00
IUUC-Pfo-096373 Poecilia formosa 84.21 7.00e-144 503.00
IUUC-Pab-098247 Pongo abelii 66.23 3.00e-120 424.00
IUUC-Pop-099186 Populus trichocarpa 30.30 6.00e-34 137.00
IUUC-Pca-100677 Procavia capensis 60.14 1.00e-91 329.00
IUUC-Ppe-101403 Prunus persica 29.10 7.00e-32 130.00
IUUC-Pva-103000 Pteropus vampyrus 66.89 9.00e-121 426.00
IUUC-Pgr-103663 Puccinia graminis 29.10 1.00e-27 117.00
IUUC-Ptt-103712 Puccinia triticina 35.38 2.00e-07 49.30
IUUC-Pte-104287 Pyrenophora teres 22.18 4.00e-13 68.90
IUUC-Pyt-104579 Pyrenophora triticirepentis 31.25 4.00e-07 48.90
IUUC-Rno-106069 Rattus norvegicus 65.89 5.00e-119 420.00
IUUC-Sha-106553 Sarcophilus harrisii 65.23 1.00e-116 412.00
IUUC-Smo-108874 Selaginella moellendorffii 32.00 3.00e-38 152.00
IUUC-Sit-110307 Setaria italica 29.29 2.00e-30 126.00
IUUC-Sly-111094 Solanum lycopersicum 29.43 1.00e-33 136.00
IUUC-Stu-112363 Solanum tuberosum 29.43 1.00e-33 137.00
IUUC-Sar-113480 Sorex araneus 65.56 4.00e-114 404.00
IUUC-Sbi-113939 Sorghum bicolor 29.97 3.00e-33 135.00
IUUC-Ssc-115644 Sus scrofa 65.89 9.00e-120 422.00
IUUC-Tru-118781 Takifugu rubripes 78.36 3.00e-140 490.00
IUUC-Tni-119672 Tetraodon nigroviridis 76.74 3.00e-36 142.00
IUUC-Tca-121795 Theobroma cacao 29.10 6.00e-35 140.00
IUUC-Tre-122037 Trichoderma reesei 32.47 3.00e-07 49.70
IUUC-Tvi-122524 Trichoderma virens 26.64 6.00e-14 71.60
IUUC-Tae-122828 Triticum aestivum 29.63 1.00e-33 136.00
IUUC-Tur-126387 Triticum urartu 29.34 5.00e-27 115.00
IUUC-Tme-127111 Tuber melanosporum 36.90 3.00e-08 53.10
IUUC-Ttr-128227 Tursiops truncatus 65.69 9.00e-119 419.00
IUUC-Vda-129924 Verticillium dahliae 25.00 1.00e-15 77.40
IUUC-Vpa-130802 Vicugna pacos 67.82 8.00e-32 130.00
IUUC-Vvi-131105 Vitis vinifera 30.64 3.00e-34 139.00
IUUC-Xtr-132830 Xenopus tropicalis 64.69 1.00e-116 412.00
IUUC-Xma-133618 Xiphophorus maculatus 83.44 8.00e-138 483.00
IUUC-Zma-135389 Zea mays 29.29 3.00e-31 129.00
Created Date 25-Jun-2017

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