iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074415

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02030953

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000004519.3	ENSOCUT00000004521.3	ENSOCUP00000003904.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-30	102.2	184	218
UBD/Beta-Prp	1.30e-46	159.2	43	279

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrt 32
           gH  ++ ++++    d +l+++s D  +k+WD+r+
   Q: 184  GHRQEILAVSWsprYDYILATASADSRVKLWDVRR 218
           8**********96543678*************986 PP

UBD/Beta-Prp

   S: 52   eaevtavkfspdgk.ilvtgseDrtikvwdls........tgkcvhtlk.....ghedsvlslsfsp.sgdklvsGshdrtirvwdlet 125
            ++v++++++p +  ++++g++D++i ++dl+        t+k v ++       h++sv +++++p ++  + s s d+t++vwd++t
   Q: 43   GSGVNTLDIEPVEGrYMLSGGSDGVIVLYDLEnssrqpfyTCKAVCSIGrnhpdVHKYSVETVQWYPhDTGMFTSSSFDKTLKVWDTNT 131
           55677777777655577777777777777777664444444444444335566667777777777775557777777777777777777 PP
   S: 126  gqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.. 210
            q    ++ +++    +++   +  +l++ G+   +v+l dlk+g++ + l+g h + +  +s+++     l+++s d++vklwd++  
   Q: 132  LQTADVFNFEETVYSHHMSPVATRhCLVAVGTRGPKVQLCDLKSGSCSHILQG-HRQEILAVSWSPRYdYILATASADSRVKLWDVRra 219
           77776344444444444555555556666777777777777777777777777.77777777777765455667777777777777765 PP
   S: 211  ..............tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
                         ++ +  + ++h+  v+ + f++++ +l++++ D+  r+W++ +g++
   Q: 220  sgclitldqhngekSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSNGEN 279
           555555555544433333555556667777777777777777777777777777776665 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MLGFLSARQV GLEDPVRLRR AESTRRVLGL ELNKDRDVER IHGSGVNTLD IEPVEGRYML 60
SGGSDGVIVL YDLENSSRQP FYTCKAVCSI GRNHPDVHKY SVETVQWYPH DTGMFTSSSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGGGGT TTTTGTCCGC GCGACAGGTG GGTTTAGAGG ACCCTGTTCG CCTCCGGAGA 60
GCAGAGTCTA CACGGAGGTA AAGCAAAGCT TATTCATTTC TCTAACGGGC CCGTTGGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

KEGG

ocu:100352258

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	30.72	6.00e-37	149.00
IUUC-Aml-002201	Ailuropoda melanoleuca	94.19	0.00e+00	787.00
IUUC-Atr-002784	Amborella trichopoda	36.21	2.00e-40	159.00
IUUC-Apl-003202	Anas platyrhynchos	82.11	0.00e+00	667.00
IUUC-Aca-004708	Anolis carolinensis	81.61	4.00e-178	617.00
IUUC-Aly-006144	Arabidopsis lyrata	29.55	1.00e-43	170.00
IUUC-Ath-006673	Arabidopsis thaliana	39.71	5.00e-45	175.00
IUUC-Acl-008195	Aspergillus clavatus	38.26	4.00e-42	165.00
IUUC-Afl-008406	Aspergillus flavus	36.84	2.00e-38	152.00
IUUC-Afu-008759	Aspergillus fumigatus	36.74	1.00e-39	157.00
IUUC-Ani-009380	Aspergillus nidulans	35.10	2.00e-40	160.00
IUUC-Ang-009820	Aspergillus niger	36.36	2.00e-38	152.00
IUUC-Aor-010092	Aspergillus oryzae	36.67	3.00e-43	169.00
IUUC-Ate-010491	Aspergillus terreus	36.65	2.00e-44	173.00
IUUC-Bta-012825	Bos taurus	93.95	0.00e+00	781.00
IUUC-Bci-013856	Botrytis cinerea	32.13	3.00e-52	199.00
IUUC-Bdi-014899	Brachypodium distachyon	33.59	5.00e-64	238.00
IUUC-Bol-015337	Brassica oleracea	32.22	5.00e-64	238.00
IUUC-Bra-018089	Brassica rapa	37.07	3.00e-44	172.00
IUUC-Cja-018725	Callithrix jacchus	94.44	0.00e+00	791.00
IUUC-Cfa-021162	Canis familiaris	94.44	0.00e+00	788.00
IUUC-Cpo-022190	Cavia porcellus	93.69	0.00e+00	787.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	37.62	8.00e-40	157.00
IUUC-Csa-023610	Chlorocebus sabaeus	95.20	0.00e+00	797.00
IUUC-Cho-024689	Choloepus hoffmanni	93.51	0.00e+00	728.00
IUUC-Cin-025324	Ciona intestinalis	39.42	1.00e-80	293.00
IUUC-Csv-026059	Ciona savignyi	38.86	1.00e-74	273.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	33.86	3.00e-38	152.00
IUUC-Cme-027182	Cyanidioschyzon merolae	28.05	6.00e-13	69.30
IUUC-Dre-028696	Danio rerio	72.75	7.00e-178	616.00
IUUC-Dno-029102	Dasypus novemcinctus	95.20	0.00e+00	798.00
IUUC-Dor-030361	Dipodomys ordii	76.52	4.00e-178	617.00
IUUC-Dse-031167	Dothistroma septosporum	29.69	1.00e-43	171.00
IUUC-Ete-032856	Echinops telfairi	75.25	1.00e-177	615.00
IUUC-Eca-033611	Equus caballus	95.27	0.00e+00	681.00
IUUC-Eeu-034583	Erinaceus europaeus	70.71	1.00e-160	559.00
IUUC-Fca-036481	Felis catus	94.19	0.00e+00	788.00
IUUC-Fal-037327	Ficedula albicollis	79.41	4.00e-168	583.00
IUUC-Fox-037684	Fusarium oxysporum	30.79	2.00e-43	170.00
IUUC-Fso-038306	Fusarium solani	32.55	7.00e-55	207.00
IUUC-Gmo-039043	Gadus morhua	68.86	2.00e-166	577.00
IUUC-Ggr-039783	Gaeumannomyces graminis	28.60	7.00e-39	155.00
IUUC-Gga-041085	Gallus gallus	85.63	0.00e+00	639.00
IUUC-Gac-042328	Gasterosteus aculeatus	67.58	5.00e-160	556.00
IUUC-Gma-043004	Glycine max	32.79	1.00e-56	214.00
IUUC-Ggo-045627	Gorilla gorilla	86.57	0.00e+00	714.00
IUUC-Hsa-046028	Homo sapiens	95.20	0.00e+00	797.00
IUUC-Hvu-047678	Hordeum vulgare	42.95	5.00e-22	98.20
IUUC-Itr-048648	Ictidomys tridecemlineatus	95.20	0.00e+00	796.00
IUUC-Kpa-049386	Komagataella pastoris	29.10	3.00e-44	172.00
IUUC-Lch-050590	Latimeria chalumnae	79.89	3.00e-162	564.00
IUUC-Lpe-051725	Leersia perrieri	33.76	2.00e-36	145.00
IUUC-Loc-051788	Lepisosteus oculatus	74.81	0.00e+00	629.00
IUUC-Lma-053082	Leptosphaeria maculans	33.08	2.00e-54	206.00
IUUC-Laf-053809	Loxodonta africana	94.46	0.00e+00	790.00
IUUC-Mcc-054998	Macaca mulatta	95.37	6.00e-163	566.00
IUUC-Meu-055929	Macropus eugenii	77.89	0.00e+00	639.00
IUUC-Mor-057003	Magnaporthe oryzae	34.03	1.00e-47	184.00
IUUC-Mtr-057921	Medicago truncatula	31.57	1.00e-55	210.00
IUUC-Mga-059449	Meleagris gallopavo	65.88	5.00e-126	443.00
IUUC-Mmr-061609	Microcebus murinus	90.79	0.00e+00	732.00
IUUC-Mdo-062564	Monodelphis domestica	86.90	0.00e+00	732.00
IUUC-Mmu-063904	Mus musculus	90.68	0.00e+00	756.00
IUUC-Mac-064716	Musa acuminata	37.05	1.00e-40	160.00
IUUC-Mpu-066617	Mustela putorius furo	93.94	0.00e+00	786.00
IUUC-Mlu-067054	Myotis lucifugus	92.93	0.00e+00	779.00
IUUC-Nfi-068467	Neosartorya fischeri	37.25	5.00e-34	138.00
IUUC-Nle-069731	Nomascus leucogenys	95.20	0.00e+00	797.00
IUUC-Opr-070297	Ochotona princeps	71.13	7.00e-91	327.00
IUUC-Ont-072558	Oreochromis niloticus	70.57	6.00e-166	576.00
IUUC-Oan-072864	Ornithorhynchus anatinus	85.96	3.00e-27	112.00
IUUC-Oba-075759	Oryza barthii	39.69	1.00e-42	167.00
IUUC-Obr-076387	Oryza brachyantha	38.86	5.00e-45	175.00
IUUC-Ogl-077924	Oryza glaberrima	40.91	5.00e-18	84.00
IUUC-Ogu-078186	Oryza glumaepatula	34.97	2.00e-62	232.00
IUUC-Oin-079389	Oryza indica	34.56	2.00e-46	179.00
IUUC-Olo-080916	Oryza longistaminata	28.92	7.00e-17	80.10
IUUC-Ome-081471	Oryza meridionalis	40.00	5.00e-40	158.00
IUUC-Oni-082449	Oryza nivara	39.18	1.00e-39	157.00
IUUC-Opu-083210	Oryza punctata	40.00	1.00e-42	167.00
IUUC-Oru-085159	Oryza rufipogon	40.53	8.00e-43	167.00
IUUC-Osa-085926	Oryza sativa	41.22	8.00e-33	132.00
IUUC-Ola-087084	Oryzias latipes	67.85	2.00e-167	582.00
IUUC-Olu-087853	Ostreococcus lucimarinus	29.55	3.00e-40	159.00
IUUC-Oga-089008	Otolemur garnettii	92.98	0.00e+00	778.00
IUUC-Oar-089259	Ovis aries	94.21	0.00e+00	783.00
IUUC-Ptr-091112	Pan troglodytes	94.40	0.00e+00	786.00
IUUC-Pan-092303	Papio anubis	93.75	9.00e-71	258.00
IUUC-Psi-093050	Pelodiscus sinensis	82.66	0.00e+00	700.00
IUUC-Pma-094259	Petromyzon marinus	57.43	2.00e-130	459.00
IUUC-Pno-094798	Phaeosphaeria nodorum	31.90	1.00e-51	197.00
IUUC-Ppa-095477	Physcomitrella patens	31.74	1.00e-54	206.00
IUUC-Pfo-096855	Poecilia formosa	67.66	2.00e-165	575.00
IUUC-Pab-098096	Pongo abelii	94.44	0.00e+00	790.00
IUUC-Pop-098800	Populus trichocarpa	35.78	3.00e-45	175.00
IUUC-Pca-100187	Procavia capensis	93.20	1.00e-114	405.00
IUUC-Ppe-101759	Prunus persica	36.24	9.00e-44	171.00
IUUC-Pva-102438	Pteropus vampyrus	78.54	9.00e-93	333.00
IUUC-Pte-104197	Pyrenophora teres	33.90	2.00e-50	192.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	34.37	3.00e-50	192.00
IUUC-Rno-106087	Rattus norvegicus	90.43	0.00e+00	758.00
IUUC-Sce-106276	Saccharomyces cerevisiae	27.32	8.00e-13	68.60
IUUC-Sha-106831	Sarcophilus harrisii	82.91	0.00e+00	692.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	33.16	8.00e-57	214.00
IUUC-Spo-108294	Schizosaccharomyces pombe	35.64	2.00e-64	239.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	33.24	3.00e-52	199.00
IUUC-Smo-109008	Selaginella moellendorffii	40.40	6.00e-74	271.00
IUUC-Sit-110300	Setaria italica	38.66	2.00e-40	160.00
IUUC-Sly-111441	Solanum lycopersicum	30.35	4.00e-48	185.00
IUUC-Stu-111995	Solanum tuberosum	30.19	5.00e-48	184.00
IUUC-Sar-113196	Sorex araneus	83.27	3.00e-129	454.00
IUUC-Sbi-113790	Sorghum bicolor	39.51	4.00e-42	165.00
IUUC-Ssc-115609	Sus scrofa	94.70	0.00e+00	795.00
IUUC-Tgu-116927	Taeniopygia guttata	80.70	0.00e+00	672.00
IUUC-Tru-118164	Takifugu rubripes	68.73	1.00e-171	595.00
IUUC-Tsy-119151	Tarsius syrichta	88.89	0.00e+00	734.00
IUUC-Tni-120896	Tetraodon nigroviridis	68.00	2.00e-162	565.00
IUUC-Tca-121592	Theobroma cacao	36.24	3.00e-44	172.00
IUUC-Tre-122023	Trichoderma reesei	34.85	5.00e-49	188.00
IUUC-Tvi-122507	Trichoderma virens	34.02	6.00e-50	191.00
IUUC-Tae-125730	Triticum aestivum	39.80	5.00e-42	165.00
IUUC-Tur-126092	Triticum urartu	30.94	5.00e-35	141.00
IUUC-Tbe-127422	Tupaia belangeri	72.43	5.00e-154	536.00
IUUC-Ttr-129097	Tursiops truncatus	92.68	0.00e+00	774.00
IUUC-Vda-130014	Verticillium dahliae	36.71	5.00e-51	195.00
IUUC-Vpa-130782	Vicugna pacos	94.46	0.00e+00	788.00
IUUC-Vvi-131494	Vitis vinifera	27.07	1.00e-43	171.00
IUUC-Xtr-132165	Xenopus tropicalis	78.11	0.00e+00	630.00
IUUC-Xma-133205	Xiphophorus maculatus	68.58	3.00e-169	587.00
IUUC-Yli-134614	Yarrowia lipolytica	34.09	4.00e-58	218.00
IUUC-Zma-135861	Zea mays	34.63	1.00e-59	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence