iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089416

Ensembl Protein ID

ENSOARP00000000775.1

UniProt Accession

W5NRI5; W5NRI5_SHEEP

Genbank Protein ID

ENSOARP00000000775

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01041847

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000000753.1	ENSOART00000000807.1	ENSOARP00000000775.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.90e-45	149.1	230	269
UBD/Beta-Prp	2.20e-75	253.8	12	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+++v  +af +d t++vs+s D+++kvWD+ t +++++
   Q: 230  GHASWVLNVAFcPDdTHFVSSSSDKSVKVWDVGTRTCVHT 269
           8***********777*****************99999875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++    +++++ ++tgs d+ +kvw+++++kl   +sl+gh+ +v +v++s++ +i +++s D++i++wdl++gk++ 
   Q: 12   EQAHDDAIWSVAWgsnkKENSETVVTGSLDDLVKVWKWRDEKLdlQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIK 100
           5678888888999988888999********************9999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   ++++l+fsp++++l++G+h+  ++++ +e+g++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 101  SIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd+ ++++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++i+++
   Q: 277  VWGVKY-NGNGSKIVSVGDDQEIHIYDC 303
           ******.999****************98 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MTNQYSILFK QEQAHDDAIW SVAWGSNKKE NSETVVTGSL DDLVKVWKWR DEKLDLQWSL 60
EGHQLGVVSV DISHTLPIAA SSSLDAHIRL WDLENGKQIK SIDAGPVDAW TLAFSPDSQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTGTCTGG CCTTTAGCCC TTCATCCTTG GTTAAGGAGA TGACCAACCA GGTAAGGCCT 60
AGGGAGAAGA AGAGTACCAG TTGGTCTCTT TGGGGGTTCG AGCCCAATAC ATTGTCTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

KEGG

oas:101121805

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	33.93	1.00e-47	183.00
IUUC-Aml-002245	Ailuropoda melanoleuca	98.36	6.00e-168	582.00
IUUC-Atr-003142	Amborella trichopoda	51.55	2.00e-38	152.00
IUUC-Apl-003179	Anas platyrhynchos	91.15	3.00e-157	547.00
IUUC-Aca-004880	Anolis carolinensis	88.85	4.00e-158	550.00
IUUC-Aly-005956	Arabidopsis lyrata	37.82	8.00e-56	210.00
IUUC-Ath-007230	Arabidopsis thaliana	37.50	1.00e-51	196.00
IUUC-Ang-009702	Aspergillus niger	29.26	6.00e-30	124.00
IUUC-Ame-011511	Astyanax mexicanus	84.36	1.00e-149	521.00
IUUC-Bta-012936	Bos taurus	100.00	1.00e-169	588.00
IUUC-Bdi-015020	Brachypodium distachyon	37.59	4.00e-47	181.00
IUUC-Bol-016345	Brassica oleracea	38.46	5.00e-57	214.00
IUUC-Bra-017323	Brassica rapa	38.46	4.00e-57	214.00
IUUC-Cja-019961	Callithrix jacchus	99.02	2.00e-168	584.00
IUUC-Cfa-020862	Canis familiaris	98.03	6.00e-167	579.00
IUUC-Cpo-021356	Cavia porcellus	98.68	1.00e-165	575.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.58	6.00e-58	217.00
IUUC-Csa-024067	Chlorocebus sabaeus	98.69	8.00e-168	582.00
IUUC-Cho-024421	Choloepus hoffmanni	83.84	7.00e-83	299.00
IUUC-Cin-025261	Ciona intestinalis	64.92	1.00e-116	412.00
IUUC-Dre-027706	Danio rerio	66.23	2.00e-110	392.00
IUUC-Dno-029084	Dasypus novemcinctus	98.70	1.00e-167	581.00
IUUC-Dor-030353	Dipodomys ordii	82.61	4.00e-123	433.00
IUUC-Dse-031348	Dothistroma septosporum	29.08	1.00e-26	113.00
IUUC-Dme-031836	Drosophila melanogaster	52.62	2.00e-88	318.00
IUUC-Ete-032261	Echinops telfairi	95.74	2.00e-161	561.00
IUUC-Eca-034231	Equus caballus	91.15	5.00e-153	533.00
IUUC-Eeu-034828	Erinaceus europaeus	97.25	1.00e-156	545.00
IUUC-Fca-036569	Felis catus	98.69	1.00e-167	582.00
IUUC-Fal-037469	Ficedula albicollis	93.11	4.00e-161	560.00
IUUC-Fox-038047	Fusarium oxysporum	33.00	2.00e-29	122.00
IUUC-Gmo-039579	Gadus morhua	84.26	1.00e-146	511.00
IUUC-Gga-040808	Gallus gallus	93.84	2.00e-154	538.00
IUUC-Gac-042100	Gasterosteus aculeatus	84.59	1.00e-147	515.00
IUUC-Gma-043509	Glycine max	40.94	6.00e-60	224.00
IUUC-Ggo-045227	Gorilla gorilla	99.02	2.00e-168	584.00
IUUC-Hsa-045839	Homo sapiens	99.02	2.00e-168	584.00
IUUC-Hvu-047591	Hordeum vulgare	37.97	9.00e-50	190.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	99.34	4.00e-169	586.00
IUUC-Lch-049549	Latimeria chalumnae	84.26	2.00e-147	514.00
IUUC-Lpe-050746	Leersia perrieri	38.59	2.00e-48	186.00
IUUC-Loc-052540	Lepisosteus oculatus	87.21	2.00e-149	521.00
IUUC-Laf-053907	Loxodonta africana	99.34	4.00e-169	586.00
IUUC-Mcc-055828	Macaca mulatta	92.62	3.00e-164	570.00
IUUC-Meu-056075	Macropus eugenii	94.90	1.00e-135	474.00
IUUC-Mtr-057728	Medicago truncatula	40.38	2.00e-56	213.00
IUUC-Mga-059872	Meleagris gallopavo	93.44	1.00e-161	561.00
IUUC-Mvi-060564	Microbotryum violaceum	32.11	6.00e-30	124.00
IUUC-Mmr-060985	Microcebus murinus	98.97	2.00e-160	558.00
IUUC-Mdo-062758	Monodelphis domestica	90.79	4.00e-159	553.00
IUUC-Mmu-063580	Mus musculus	97.05	3.00e-166	577.00
IUUC-Mac-064880	Musa acuminata	40.19	7.00e-58	217.00
IUUC-Mpu-066577	Mustela putorius furo	97.70	2.00e-166	577.00
IUUC-Nle-069573	Nomascus leucogenys	99.02	2.00e-168	584.00
IUUC-Opr-070216	Ochotona princeps	97.34	3.00e-164	570.00
IUUC-Ont-071981	Oreochromis niloticus	85.90	2.00e-150	525.00
IUUC-Oan-073223	Ornithorhynchus anatinus	94.44	6.00e-108	382.00
IUUC-Ocu-074199	Oryctolagus cuniculus	84.59	2.00e-139	487.00
IUUC-Oba-075255	Oryza barthii	40.00	1.00e-41	163.00
IUUC-Obr-076168	Oryza brachyantha	47.20	1.00e-35	143.00
IUUC-Ogl-077777	Oryza glaberrima	38.39	6.00e-49	187.00
IUUC-Ogu-078780	Oryza glumaepatula	38.39	6.00e-49	187.00
IUUC-Oin-079228	Oryza indica	38.39	1.00e-51	196.00
IUUC-Ome-081421	Oryza meridionalis	38.39	3.00e-48	185.00
IUUC-Oni-082997	Oryza nivara	38.39	1.00e-51	196.00
IUUC-Opu-083931	Oryza punctata	38.71	4.00e-49	188.00
IUUC-Oru-084645	Oryza rufipogon	38.39	6.00e-49	187.00
IUUC-Osa-085842	Oryza sativa	38.39	1.00e-51	196.00
IUUC-Ola-086696	Oryzias latipes	85.25	2.00e-146	511.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.91	1.00e-41	162.00
IUUC-Oga-088272	Otolemur garnettii	98.68	1.00e-166	578.00
IUUC-Ptr-090944	Pan troglodytes	99.02	2.00e-168	584.00
IUUC-Pan-091861	Papio anubis	99.02	2.00e-168	584.00
IUUC-Psi-093750	Pelodiscus sinensis	94.43	2.00e-162	564.00
IUUC-Pma-094608	Petromyzon marinus	80.32	6.00e-136	476.00
IUUC-Ppa-095737	Physcomitrella patens	40.38	8.00e-57	213.00
IUUC-Pfo-096479	Poecilia formosa	86.56	1.00e-144	505.00
IUUC-Pab-098179	Pongo abelii	99.02	2.00e-168	584.00
IUUC-Pop-099532	Populus trichocarpa	40.91	3.00e-56	212.00
IUUC-Pca-100664	Procavia capensis	76.45	6.00e-106	376.00
IUUC-Ppe-102056	Prunus persica	39.94	4.00e-58	218.00
IUUC-Pva-102859	Pteropus vampyrus	98.69	5.00e-168	583.00
IUUC-Rno-105826	Rattus norvegicus	96.72	1.00e-165	575.00
IUUC-Sha-106660	Sarcophilus harrisii	92.69	2.00e-153	534.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.22	3.00e-36	145.00
IUUC-Spo-108244	Schizosaccharomyces pombe	31.39	2.00e-35	142.00
IUUC-Smo-109234	Selaginella moellendorffii	42.81	2.00e-61	228.00
IUUC-Sit-110048	Setaria italica	36.86	1.00e-40	160.00
IUUC-Sly-111618	Solanum lycopersicum	38.46	2.00e-52	198.00
IUUC-Stu-112543	Solanum tuberosum	38.78	2.00e-55	209.00
IUUC-Sar-113743	Sorex araneus	78.36	2.00e-130	457.00
IUUC-Sbi-114309	Sorghum bicolor	38.57	7.00e-42	164.00
IUUC-Ssc-115560	Sus scrofa	93.77	1.00e-155	542.00
IUUC-Tgu-117300	Taeniopygia guttata	93.44	1.00e-161	561.00
IUUC-Tru-117933	Takifugu rubripes	85.25	7.00e-150	522.00
IUUC-Tsy-119574	Tarsius syrichta	88.52	5.00e-145	506.00
IUUC-Tni-120191	Tetraodon nigroviridis	87.34	5.00e-113	399.00
IUUC-Tca-120983	Theobroma cacao	40.13	2.00e-57	216.00
IUUC-Tae-124056	Triticum aestivum	36.16	8.00e-50	190.00
IUUC-Tur-126711	Triticum urartu	36.05	8.00e-49	187.00
IUUC-Tbe-127802	Tupaia belangeri	98.69	1.00e-167	582.00
IUUC-Ttr-128861	Tursiops truncatus	99.06	7.00e-57	213.00
IUUC-Vpa-130618	Vicugna pacos	95.55	1.00e-135	475.00
IUUC-Vvi-130981	Vitis vinifera	40.38	6.00e-56	211.00
IUUC-Xtr-132460	Xenopus tropicalis	85.90	5.00e-146	509.00
IUUC-Xma-134154	Xiphophorus maculatus	86.56	6.00e-145	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence