iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090082

Ensembl Protein ID

ENSOARP00000019910.1

UniProt Accession

W5QB15; W5QB15_SHEEP

Genbank Protein ID

ENSOARP00000019910

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01023208

Gene Name

UBE2T

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000018545.1	ENSOART00000020185.1	ENSOARP00000019910.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.10e-42	143.4	6	147

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpe..dYPfkPPkvkfltkifhPnvyenGkvClsilk 87
           Rlk+el+ l+++pp+gi++ ++ +  + +++++ilG ++tpYe+gvFkle+++pe  +YPf+PP+++flt+i+hPn++++G++Cl++lk
   Q: 6    RLKRELSLLAAEPPPGITCWQDGD-RMEDLRAQILGGANTPYEKGVFKLEVHIPEsqRYPFEPPQIRFLTPIYHPNIDAAGRICLDVLK 93
           99**********************.5***************************96337******************************9 PP
   S: 88   ..eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
             ++  W+p l++++ l+s+q+l+aepnp++pl +++++++k n+  + k++r+
   Q: 94   lpPKGSWRPSLNIATLLTSVQQLMAEPNPDDPLMADISSEFKYNKPVFLKNARQ 147
           9899******************************************99999875 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MQRTSRLKRE LSLLAAEPPP GITCWQDGDR MEDLRAQILG GANTPYEKGV FKLEVHIPES 60
QRYPFEPPQI RFLTPIYHPN IDAAGRICLD VLKLPPKGSW RPSLNIATLL TSVQQLMAEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCTTCC CCCCCCCGCC ACGCCCACCG GCTGCTCCCG CCCCCCCCCC ACGTTCATTA 60
ATTGTTATAT TTGTTGTTTT ATCCTTGCTG ATTCCCAGTG CCCGCTTACT GAGAGGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005730--C:nucleolus
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006281--P:DNA repair
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000366	Aegilops tauschii	52.94	5.00e-44	172.00
IUUC-Aml-001392	Ailuropoda melanoleuca	79.90	2.00e-89	321.00
IUUC-Atr-003069	Amborella trichopoda	45.45	1.00e-47	183.00
IUUC-Apl-003914	Anas platyrhynchos	79.49	5.00e-74	269.00
IUUC-Aca-004381	Anolis carolinensis	65.50	6.00e-75	273.00
IUUC-Aly-006059	Arabidopsis lyrata	49.38	1.00e-42	166.00
IUUC-Ath-007669	Arabidopsis thaliana	55.91	9.00e-41	160.00
IUUC-Ame-011372	Astyanax mexicanus	68.26	2.00e-65	241.00
IUUC-Bta-012479	Bos taurus	92.39	7.00e-106	375.00
IUUC-Bdi-014043	Brachypodium distachyon	54.90	5.00e-48	186.00
IUUC-Bol-016011	Brassica oleracea	47.09	3.00e-41	162.00
IUUC-Bra-017419	Brassica rapa	45.81	3.00e-40	159.00
IUUC-Cja-019773	Callithrix jacchus	78.00	3.00e-87	313.00
IUUC-Cfa-020043	Canis familiaris	79.40	6.00e-89	319.00
IUUC-Cpo-021481	Cavia porcellus	78.39	9.00e-89	318.00
IUUC-Csa-024083	Chlorocebus sabaeus	78.89	9.00e-90	322.00
IUUC-Cho-024386	Choloepus hoffmanni	80.00	2.00e-83	301.00
IUUC-Cin-025419	Ciona intestinalis	60.90	1.00e-57	215.00
IUUC-Csv-026224	Ciona savignyi	62.42	2.00e-59	221.00
IUUC-Cme-027179	Cyanidioschyzon merolae	50.32	2.00e-40	157.00
IUUC-Dre-028800	Danio rerio	75.64	5.00e-71	260.00
IUUC-Dno-029833	Dasypus novemcinctus	78.39	1.00e-89	321.00
IUUC-Ete-032625	Echinops telfairi	81.41	1.00e-68	251.00
IUUC-Eca-033821	Equus caballus	87.82	6.00e-80	288.00
IUUC-Eeu-034578	Erinaceus europaeus	78.10	1.00e-60	224.00
IUUC-Fca-036398	Felis catus	81.91	2.00e-92	331.00
IUUC-Fal-037564	Ficedula albicollis	68.53	7.00e-75	272.00
IUUC-Gmo-039142	Gadus morhua	75.64	7.00e-69	252.00
IUUC-Gga-041054	Gallus gallus	65.62	9.00e-72	262.00
IUUC-Gac-041370	Gasterosteus aculeatus	73.72	6.00e-69	252.00
IUUC-Ggo-045370	Gorilla gorilla	79.40	2.00e-89	321.00
IUUC-Hsa-046513	Homo sapiens	79.90	7.00e-90	322.00
IUUC-Hvu-047694	Hordeum vulgare	52.94	9.00e-46	177.00
IUUC-Itr-049076	Ictidomys tridecemlineatus	75.88	3.00e-86	310.00
IUUC-Lch-050484	Latimeria chalumnae	64.13	9.00e-65	239.00
IUUC-Loc-051967	Lepisosteus oculatus	72.44	9.00e-69	252.00
IUUC-Laf-053377	Loxodonta africana	77.39	2.00e-87	314.00
IUUC-Mcc-055453	Macaca mulatta	78.39	3.00e-89	320.00
IUUC-Meu-056745	Macropus eugenii	73.10	2.00e-82	297.00
IUUC-Mga-059729	Meleagris gallopavo	66.15	1.00e-72	265.00
IUUC-Mmr-060581	Microcebus murinus	78.39	1.00e-88	318.00
IUUC-Mdo-062434	Monodelphis domestica	72.91	4.00e-79	288.00
IUUC-Mmu-064379	Mus musculus	74.75	2.00e-83	301.00
IUUC-Mac-064647	Musa acuminata	52.05	1.00e-42	165.00
IUUC-Mpu-066713	Mustela putorius furo	78.89	6.00e-89	319.00
IUUC-Mlu-067525	Myotis lucifugus	87.18	4.00e-79	286.00
IUUC-Nle-069757	Nomascus leucogenys	80.40	2.00e-90	324.00
IUUC-Opr-070756	Ochotona princeps	74.87	1.00e-84	305.00
IUUC-Ont-071956	Oreochromis niloticus	75.64	5.00e-70	256.00
IUUC-Oan-072745	Ornithorhynchus anatinus	80.13	3.00e-74	270.00
IUUC-Ocu-074423	Oryctolagus cuniculus	74.87	7.00e-83	299.00
IUUC-Oba-075569	Oryza barthii	54.14	8.00e-47	181.00
IUUC-Obr-076131	Oryza brachyantha	54.14	8.00e-47	181.00
IUUC-Ogl-077132	Oryza glaberrima	54.14	8.00e-47	181.00
IUUC-Ogu-078880	Oryza glumaepatula	54.78	3.00e-47	182.00
IUUC-Oin-079748	Oryza indica	54.78	2.00e-47	183.00
IUUC-Olo-080501	Oryza longistaminata	54.78	1.00e-47	184.00
IUUC-Ome-081248	Oryza meridionalis	54.14	8.00e-47	181.00
IUUC-Oni-083033	Oryza nivara	54.78	2.00e-47	183.00
IUUC-Opu-083664	Oryza punctata	55.19	3.00e-47	182.00
IUUC-Oru-084580	Oryza rufipogon	54.78	2.00e-47	183.00
IUUC-Osa-085721	Oryza sativa	54.78	2.00e-47	183.00
IUUC-Ola-087559	Oryzias latipes	72.78	3.00e-68	250.00
IUUC-Oga-088420	Otolemur garnettii	78.50	2.00e-87	315.00
IUUC-Ptr-091134	Pan troglodytes	79.40	3.00e-89	320.00
IUUC-Pan-091735	Papio anubis	78.89	9.00e-90	322.00
IUUC-Psi-094064	Pelodiscus sinensis	69.15	7.00e-78	282.00
IUUC-Pma-094609	Petromyzon marinus	70.59	1.00e-64	238.00
IUUC-Ppa-095553	Physcomitrella patens	54.84	8.00e-47	181.00
IUUC-Pfo-096710	Poecilia formosa	74.19	5.00e-68	249.00
IUUC-Pab-098126	Pongo abelii	79.90	7.00e-90	322.00
IUUC-Pop-099108	Populus trichocarpa	50.65	2.00e-43	170.00
IUUC-Pca-100338	Procavia capensis	77.89	7.00e-88	316.00
IUUC-Ppe-101239	Prunus persica	52.14	3.00e-39	156.00
IUUC-Pva-102756	Pteropus vampyrus	75.00	2.00e-61	227.00
IUUC-Rno-105211	Rattus norvegicus	74.24	6.00e-79	286.00
IUUC-Sha-106969	Sarcophilus harrisii	68.47	2.00e-72	265.00
IUUC-Smo-109052	Selaginella moellendorffii	53.55	2.00e-42	164.00
IUUC-Sit-110464	Setaria italica	54.90	6.00e-45	175.00
IUUC-Sly-110971	Solanum lycopersicum	53.90	4.00e-43	169.00
IUUC-Stu-112126	Solanum tuberosum	53.80	4.00e-44	172.00
IUUC-Sar-113633	Sorex araneus	76.88	2.00e-87	314.00
IUUC-Sbi-114875	Sorghum bicolor	54.25	1.00e-45	177.00
IUUC-Ssc-116375	Sus scrofa	80.40	2.00e-86	311.00
IUUC-Tgu-117292	Taeniopygia guttata	78.71	3.00e-71	260.00
IUUC-Tru-118157	Takifugu rubripes	64.74	1.00e-56	211.00
IUUC-Tsy-119260	Tarsius syrichta	80.20	8.00e-91	325.00
IUUC-Tni-120162	Tetraodon nigroviridis	60.41	2.00e-67	248.00
IUUC-Tca-121255	Theobroma cacao	49.71	6.00e-36	145.00
IUUC-Tae-123184	Triticum aestivum	52.94	6.00e-44	172.00
IUUC-Tbe-127296	Tupaia belangeri	78.39	2.00e-89	321.00
IUUC-Ttr-128443	Tursiops truncatus	84.92	2.00e-93	334.00
IUUC-Vpa-130689	Vicugna pacos	80.81	2.00e-92	331.00
IUUC-Vvi-130925	Vitis vinifera	52.15	4.00e-44	170.00
IUUC-Xma-133779	Xiphophorus maculatus	74.19	4.00e-68	250.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence