iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026154

UUCD1 version

UUC-CiS-00245

Ensembl Protein ID

ENSCSAVP00000002664.1

UniProt Accession

H2YBG6; H2YBG6_CIOSA

Protein Name

Protein HIRA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000001574.1	ENSCSAVT00000002706.1	ENSCSAVP00000002664.1
ENSCSAVG00000001574.1	ENSCSAVT00000002707.1	ENSCSAVP00000002665.1
ENSCSAVG00000001574.1	ENSCSAVT00000002708.1	ENSCSAVP00000002666.1
ENSCSAVG00000001574.1	ENSCSAVT00000002709.1	ENSCSAVP00000002667.1
ENSCSAVG00000001574.1	ENSCSAVT00000002710.1	ENSCSAVP00000002668.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-22	78.7	131	164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gHt++v +la+ ++   l+s+s D+t+ vWD+ +
   Q: 131  GHTGDVLDLAWsPGdQWLASCSIDNTVVVWDVQK 164
           8***********66699**************976 PP

Organism

Ciona savignyi

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MKLFKPPWVT HDEKPVFSID IHPDESRFAT GGQGDGGSSG KVIIWNMTPV VNEKEEAKEN 60
VPKVLCVMDN HLACVNCVRW SCNGRYLASG GDDRLIMIWQ FAGLIRVCLG VNPPFKTAIG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATTAAGGC ATTGTTGCTT GCAAAAAAGT ATCGTCGTTA GTGTAATTCG TTAGTGTACT 60
ATTTCAAGTA TGAAGCTGTT CAAACCTCCA TGGGTGACTC ATGATGGTAA ATAATATTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	35.86	4.00e-84	304.00
IUUC-Aml-001723	Ailuropoda melanoleuca	52.07	2.00e-149	521.00
IUUC-Atr-003132	Amborella trichopoda	36.49	8.00e-86	310.00
IUUC-Apl-003197	Anas platyrhynchos	55.06	1.00e-150	525.00
IUUC-Aca-004733	Anolis carolinensis	56.73	3.00e-161	560.00
IUUC-Aly-005446	Arabidopsis lyrata	35.50	5.00e-81	294.00
IUUC-Ath-007627	Arabidopsis thaliana	36.66	1.00e-83	303.00
IUUC-Ago-007766	Ashbya gossypii	30.23	5.00e-54	204.00
IUUC-Acl-008104	Aspergillus clavatus	33.66	4.00e-60	225.00
IUUC-Afl-008591	Aspergillus flavus	33.26	2.00e-61	229.00
IUUC-Afu-008781	Aspergillus fumigatus	35.10	8.00e-57	214.00
IUUC-Ani-009272	Aspergillus nidulans	33.60	3.00e-52	198.00
IUUC-Ang-009655	Aspergillus niger	33.83	8.00e-60	224.00
IUUC-Aor-010119	Aspergillus oryzae	33.26	2.00e-61	229.00
IUUC-Ate-010530	Aspergillus terreus	30.77	1.00e-52	200.00
IUUC-Bgr-012237	Blumeria graminis	32.43	3.00e-56	212.00
IUUC-Bta-013320	Bos taurus	53.52	1.00e-151	529.00
IUUC-Bci-013795	Botrytis cinerea	32.25	4.00e-59	221.00
IUUC-Bdi-014075	Brachypodium distachyon	39.14	7.00e-88	317.00
IUUC-Bol-016440	Brassica oleracea	37.06	4.00e-83	301.00
IUUC-Bra-016651	Brassica rapa	36.47	1.00e-83	302.00
IUUC-Cel-018692	Caenorhabditis elegans	35.92	2.00e-70	258.00
IUUC-Cja-018987	Callithrix jacchus	54.85	1.00e-139	489.00
IUUC-Cfa-020132	Canis familiaris	52.07	2.00e-149	521.00
IUUC-Cpo-021484	Cavia porcellus	54.34	2.00e-154	538.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	32.82	1.00e-53	203.00
IUUC-Csa-023081	Chlorocebus sabaeus	55.01	9.00e-155	539.00
IUUC-Cin-025182	Ciona intestinalis	83.16	0.00e+00	793.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	32.29	3.00e-60	225.00
IUUC-Cne-026891	Cryptococcus neoformans	40.00	1.00e-80	292.00
IUUC-Cme-027349	Cyanidioschyzon merolae	28.65	5.00e-48	184.00
IUUC-Dre-027655	Danio rerio	55.88	2.00e-159	555.00
IUUC-Dno-029557	Dasypus novemcinctus	51.63	6.00e-129	453.00
IUUC-Dor-030687	Dipodomys ordii	49.89	3.00e-130	457.00
IUUC-Dse-031334	Dothistroma septosporum	31.89	4.00e-55	208.00
IUUC-Dme-031746	Drosophila melanogaster	51.60	8.00e-141	493.00
IUUC-Ete-032384	Echinops telfairi	47.26	2.00e-121	428.00
IUUC-Eca-033430	Equus caballus	54.85	6.00e-149	520.00
IUUC-Fca-036121	Felis catus	51.66	4.00e-150	524.00
IUUC-Fal-036817	Ficedula albicollis	54.97	2.00e-150	525.00
IUUC-Fox-037906	Fusarium oxysporum	33.65	5.00e-62	230.00
IUUC-Fso-038409	Fusarium solani	33.02	8.00e-61	227.00
IUUC-Gmo-039151	Gadus morhua	63.14	1.00e-146	512.00
IUUC-Ggr-040016	Gaeumannomyces graminis	33.17	9.00e-62	230.00
IUUC-Gga-040936	Gallus gallus	55.92	1.00e-156	545.00
IUUC-Gac-041405	Gasterosteus aculeatus	52.27	1.00e-143	502.00
IUUC-Gma-044252	Glycine max	36.81	3.00e-85	308.00
IUUC-Ggo-045430	Gorilla gorilla	55.01	7.00e-155	539.00
IUUC-Hsa-046442	Homo sapiens	55.01	5.00e-155	540.00
IUUC-Hvu-047587	Hordeum vulgare	36.56	3.00e-77	281.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	63.46	3.00e-111	392.00
IUUC-Kpa-049145	Komagataella pastoris	28.60	3.00e-59	222.00
IUUC-Lch-050474	Latimeria chalumnae	53.97	2.00e-145	508.00
IUUC-Lpe-051209	Leersia perrieri	36.58	7.00e-78	283.00
IUUC-Loc-052119	Lepisosteus oculatus	53.72	6.00e-153	533.00
IUUC-Lma-053237	Leptosphaeria maculans	33.33	6.00e-57	214.00
IUUC-Laf-053718	Loxodonta africana	54.73	2.00e-155	541.00
IUUC-Mcc-055621	Macaca mulatta	53.97	1.00e-139	488.00
IUUC-Meu-055914	Macropus eugenii	44.53	8.00e-110	390.00
IUUC-Mor-057090	Magnaporthe oryzae	34.24	1.00e-62	233.00
IUUC-Mpo-057364	Magnaporthe poae	33.17	7.00e-62	230.00
IUUC-Mtr-057744	Medicago truncatula	38.13	6.00e-88	317.00
IUUC-Mla-058914	Melampsora laricipopulina	37.42	6.00e-83	300.00
IUUC-Mga-060181	Meleagris gallopavo	55.53	2.00e-151	528.00
IUUC-Mvi-060432	Microbotryum violaceum	36.13	4.00e-67	248.00
IUUC-Mmr-060871	Microcebus murinus	55.31	5.00e-156	543.00
IUUC-Mdo-062301	Monodelphis domestica	54.96	5.00e-154	536.00
IUUC-Mmu-063888	Mus musculus	55.24	3.00e-155	541.00
IUUC-Mac-065137	Musa acuminata	38.83	2.00e-86	311.00
IUUC-Mpu-066732	Mustela putorius furo	38.97	0.00e+00	644.00
IUUC-Mlu-067542	Myotis lucifugus	54.32	4.00e-151	527.00
IUUC-Nfi-068396	Neosartorya fischeri	35.10	6.00e-57	214.00
IUUC-Ncr-068842	Neurospora crassa	32.45	3.00e-61	228.00
IUUC-Nle-070156	Nomascus leucogenys	55.10	6.00e-155	540.00
IUUC-Opr-070808	Ochotona princeps	52.72	7.00e-106	377.00
IUUC-Ont-072105	Oreochromis niloticus	54.53	8.00e-156	542.00
IUUC-Ocu-074962	Oryctolagus cuniculus	53.14	4.00e-150	524.00
IUUC-Oba-075178	Oryza barthii	37.11	2.00e-85	309.00
IUUC-Obr-076399	Oryza brachyantha	37.11	9.00e-85	306.00
IUUC-Ogu-078797	Oryza glumaepatula	37.11	2.00e-85	309.00
IUUC-Oin-080085	Oryza indica	36.48	6.00e-77	280.00
IUUC-Olo-081048	Oryza longistaminata	41.33	3.00e-64	239.00
IUUC-Ome-081324	Oryza meridionalis	37.11	2.00e-85	308.00
IUUC-Oni-082548	Oryza nivara	37.11	2.00e-85	308.00
IUUC-Opu-084008	Oryza punctata	40.77	2.00e-84	305.00
IUUC-Oru-084339	Oryza rufipogon	36.91	6.00e-85	307.00
IUUC-Osa-085782	Oryza sativa	36.91	6.00e-85	307.00
IUUC-Ola-087302	Oryzias latipes	52.26	2.00e-143	501.00
IUUC-Olu-087611	Ostreococcus lucimarinus	35.90	3.00e-83	301.00
IUUC-Oga-087935	Otolemur garnettii	54.85	1.00e-150	525.00
IUUC-Oar-089229	Ovis aries	49.69	7.00e-122	430.00
IUUC-Ptr-090715	Pan troglodytes	55.01	7.00e-155	540.00
IUUC-Pan-092318	Papio anubis	54.83	3.00e-149	521.00
IUUC-Psi-094053	Pelodiscus sinensis	54.49	6.00e-150	523.00
IUUC-Pno-094985	Phaeosphaeria nodorum	32.20	3.00e-51	195.00
IUUC-Ppa-095499	Physcomitrella patens	35.28	2.00e-83	302.00
IUUC-Pfo-096857	Poecilia formosa	40.32	0.00e+00	686.00
IUUC-Pab-098047	Pongo abelii	55.01	6.00e-155	540.00
IUUC-Pop-099587	Populus trichocarpa	36.99	2.00e-84	305.00
IUUC-Pca-100558	Procavia capensis	60.87	2.00e-76	279.00
IUUC-Ppe-101261	Prunus persica	36.82	2.00e-84	306.00
IUUC-Pva-102683	Pteropus vampyrus	55.03	5.00e-153	533.00
IUUC-Pgr-103660	Puccinia graminis	35.23	1.00e-72	266.00
IUUC-Ptt-103900	Puccinia triticina	37.14	6.00e-76	277.00
IUUC-Pte-104209	Pyrenophora teres	32.33	1.00e-58	219.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	32.33	4.00e-58	218.00
IUUC-Rno-105566	Rattus norvegicus	55.24	1.00e-155	541.00
IUUC-Sce-106291	Saccharomyces cerevisiae	30.34	4.00e-54	204.00
IUUC-Sha-107514	Sarcophilus harrisii	51.10	3.00e-132	464.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	36.32	1.00e-71	263.00
IUUC-Spo-108162	Schizosaccharomyces pombe	36.18	3.00e-70	258.00
IUUC-Ssl-108607	Sclerotinia sclerotiorum	32.87	3.00e-20	92.00
IUUC-Smo-109186	Selaginella moellendorffii	40.57	3.00e-87	315.00
IUUC-Sit-109980	Setaria italica	38.79	1.00e-87	316.00
IUUC-Sly-111547	Solanum lycopersicum	35.06	9.00e-83	300.00
IUUC-Stu-112705	Solanum tuberosum	35.80	1.00e-83	303.00
IUUC-Sar-113222	Sorex araneus	52.64	3.00e-139	487.00
IUUC-Sbi-114272	Sorghum bicolor	37.57	3.00e-87	315.00
IUUC-Sre-115061	Sporisorium reilianum	34.03	2.00e-74	272.00
IUUC-Ssc-116364	Sus scrofa	39.36	0.00e+00	654.00
IUUC-Tgu-116645	Taeniopygia guttata	54.97	1.00e-150	525.00
IUUC-Tru-117590	Takifugu rubripes	56.56	3.00e-161	561.00
IUUC-Tsy-119212	Tarsius syrichta	51.69	1.00e-133	469.00
IUUC-Tni-119915	Tetraodon nigroviridis	55.79	9.00e-160	556.00
IUUC-Tca-121765	Theobroma cacao	35.76	6.00e-84	304.00
IUUC-Tre-121887	Trichoderma reesei	33.33	1.00e-54	207.00
IUUC-Tvi-122262	Trichoderma virens	33.41	6.00e-55	207.00
IUUC-Tae-123476	Triticum aestivum	30.79	9.00e-37	146.00
IUUC-Tur-126483	Triticum urartu	38.01	1.00e-87	316.00
IUUC-Tme-127202	Tuber melanosporum	29.85	2.00e-47	182.00
IUUC-Tbe-127350	Tupaia belangeri	48.63	1.00e-98	352.00
IUUC-Ttr-129077	Tursiops truncatus	37.75	4.00e-179	620.00
IUUC-Uma-129465	Ustilago maydis	35.42	3.00e-77	281.00
IUUC-Vda-129844	Verticillium dahliae	33.08	3.00e-60	225.00
IUUC-Vvi-131397	Vitis vinifera	38.22	6.00e-89	320.00
IUUC-Xtr-132057	Xenopus tropicalis	55.44	9.00e-160	556.00
IUUC-Xma-134139	Xiphophorus maculatus	54.09	2.00e-138	484.00
IUUC-Yli-134424	Yarrowia lipolytica	31.74	1.00e-57	216.00
IUUC-Zma-135839	Zea mays	37.43	7.00e-87	313.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence