iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-122812

Ensembl Protein ID

TRIAE_CS42_2AS_TGACv1_113019_AA0349900.1

UniProt Accession

A0A1D6RK67; A0A1D6RK67_WHEAT

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_2AS_TGACv1_113019_AA0349900	TRIAE_CS42_2AS_TGACv1_113019_AA0349900.1	TRIAE_CS42_2AS_TGACv1_113019_AA0349900.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.10e-170	568.8	449	936

Active Site

Position(s)	Description	Evidence
630	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLf 64
           YD Q+ ++G++ q+k+++a+ ++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLf
   Q: 449  YDAQVSVFGSKLQKKMEEANTFVVGSGALGCEFLKNLALMGVscsskGKLTITDDDIIEKSNLSRQFLF 517
           ********************************************************************* PP
   S: 65   raedvgksKAevaaealkelnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlc 130
           r++++g+ K+ vaa a+  +np+ +++a +++ ++++e+++   F + +dvV++aldn+ ar++++ +c
   Q: 518  RDWNIGQAKSTVAATAASAINPSLHIDALQNRACPDTENVFhdtFWEGLDVVINALDNVNARMYMDMRC 586
           ***************************************8899999999******************** PP
   S: 131  lnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa......... 190
           l+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa         
   Q: 587  LYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArsefeglle 655
           ********************************************************************* PP
   S: 191  ...vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikql 256
                +n +l++ a+      k   ++ +e +++v++ l++ + ++f+++i++a+ +f+ +++n +kql
   Q: 656  ktpNEVNSFLSNPAQYAAAMRKAGDAQARELLERVSECLNKDRCSTFDDCISWARLKFEDYFSNRVKQL 724
           **99999999999999999999*********************************************** PP
   S: 257  lksfecdivtkskspfwv................................................... 274
           +  f+ d  t+ ++pfw+                                                   
   Q: 725  TFTFPEDAATSMGAPFWSapkrfpralqfsaadqshlnfimsasilraesfgvaipewakdtskladvv 793
           ************************999999999999999999999999999999999999888777777 PP
   S: 275  ...sfcsnaealqvpekvekdeevvkasap.....lylllralerfekk..kgrkpgelsfekddds.. 331
               +++++ ++ v+  ++++  ++++++      ++ ll++l++ +k   +g +++ ++fekddd   
   Q: 794  nkiAVPTFEPKQGVNIVTDEKASNLSSTSVddvavIEDLLAKLQEYAKMlpPGFQMKPIQFEKDDDTnf 862
           77744444444444444444444443333355567788888888888754489**************** PP
   S: 332  avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknf 398
           ++dl+  +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv++g  + e ++n+
   Q: 863  HMDLISGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVITGehPVEDYRNT 930
           ********************.**************************************999999**** PP
   S: 399  flfdae 404
           f ++a+
   Q: 931  FANLAL 936
           *99875 PP

Organism

Triticum aestivum

Protein Sequence
(Fasta)

MLPSKRPSDA AAGDENGRGG DAKRPRLGET EGAGGGGGSN GAAPQEIDED LHSRQLAVYG 60
RETMRRLFAS DVLVSGLNGL GAEIAKNLAL AGVKSVTIHD VKTVEMWDLS GNFFLSEDDI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTCCAAAC GCGCTGCCAG CACCAGCGCC GCCTCCCCCC TTCCCCATCC CCCTCCCTCC 60
CCCCGCCGCC CGCCCCACGA ATCAGTACCC CCTCCCGAAG CTCCCACGCC GCCCCGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Tur-126011	Triticum urartu	93.43	0.00e+00	2028.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence