iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005884.3	ENSMMUT00000008236.3	ENSMMUP00000007742.3
ENSMMUG00000005884.3	ENSMMUT00000074422.1	ENSMMUP00000050574.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.90e-138	462.7	10	421

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++   +vl+vGagg+GcEllKnLvl+G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n++a+++si++
   Q: 10   ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMN 98
           56799999********************************************************************************* PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+
   Q: 99   PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIV 187
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e++++++++e+++++++++ ++++i++k++ak+t ++ +k ++k f++di++  ++++++ 
   Q: 188  WAkYLFNQLFGEEDADQEVSP--DRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDpVKLFTKLFKDDIRYLLTMDKLWr 274
           *********************..799*************************************************************** PP
   S: 275  .................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaan 341
                            +  + ++++++p+ ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aan
   Q: 275  krkppvpldwaevqsqgEETNATDQQNEPQLGLKDQQVLDVKSYarlfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAAN 360
           ****************9999999*******************************************...68****************** PP
   S: 342  lraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           lr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk ++++++fl+++
   Q: 361  LRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQ 421
           **********.***********************************************9965 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MALSRGLPRE LAEAVAGGRV LVVGAGGIGC ELLKNLVLTG FSHIDLIDLD TIDVSNLNRQ 60
FLFQKKHVGR SKAQVAKESV LQFYPKANIV AYHDSIMNPD YNVEFFRQFI LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCACCCGCTT CCGGCCGCGG CTTGGTTCTC CCGCCTCCGC CTCCGCCGCG GCTCGTGGTT 60
GTCCCGCCAT GGCACTGTCG CGGGGGCTGC CCCGGGAGCT GGCTGAGGCG GTGGCCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

KEGG

mcc:705808

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	38.76	3.00e-108	385.00
IUUC-Aml-001662	Ailuropoda melanoleuca	97.19	0.00e+00	1246.00
IUUC-Atr-002636	Amborella trichopoda	40.00	3.00e-113	402.00
IUUC-Apl-003369	Anas platyrhynchos	88.89	0.00e+00	1026.00
IUUC-Aca-004490	Anolis carolinensis	83.23	0.00e+00	923.00
IUUC-Aly-006359	Arabidopsis lyrata	41.58	2.00e-104	373.00
IUUC-Ath-007667	Arabidopsis thaliana	42.12	4.00e-108	385.00
IUUC-Ago-007844	Ashbya gossypii	34.78	2.00e-85	310.00
IUUC-Acl-008270	Aspergillus clavatus	43.60	9.00e-106	377.00
IUUC-Afl-008674	Aspergillus flavus	43.29	1.00e-112	400.00
IUUC-Afu-008883	Aspergillus fumigatus	41.87	7.00e-107	381.00
IUUC-Ani-009500	Aspergillus nidulans	45.35	7.00e-117	414.00
IUUC-Ang-009535	Aspergillus niger	43.65	6.00e-111	394.00
IUUC-Aor-010223	Aspergillus oryzae	44.24	2.00e-114	406.00
IUUC-Ate-010282	Aspergillus terreus	44.17	7.00e-90	324.00
IUUC-Ame-011736	Astyanax mexicanus	78.16	0.00e+00	993.00
IUUC-Bgr-012166	Blumeria graminis	42.26	1.00e-98	353.00
IUUC-Bta-012589	Bos taurus	97.50	0.00e+00	1252.00
IUUC-Bci-013802	Botrytis cinerea	42.72	7.00e-101	361.00
IUUC-Bdi-014697	Brachypodium distachyon	39.72	9.00e-113	400.00
IUUC-Bol-016315	Brassica oleracea	39.14	7.00e-110	391.00
IUUC-Bra-018066	Brassica rapa	42.09	9.00e-109	387.00
IUUC-Cel-018708	Caenorhabditis elegans	46.48	4.00e-133	468.00
IUUC-Cja-019120	Callithrix jacchus	99.06	0.00e+00	1225.00
IUUC-Cfa-021061	Canis familiaris	97.66	0.00e+00	1253.00
IUUC-Cpo-021842	Cavia porcellus	97.34	0.00e+00	1208.00
IUUC-Csa-024104	Chlorocebus sabaeus	99.38	0.00e+00	1188.00
IUUC-Cho-024332	Choloepus hoffmanni	85.39	0.00e+00	873.00
IUUC-Cin-025363	Ciona intestinalis	61.87	0.00e+00	682.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	43.39	4.00e-99	355.00
IUUC-Cne-026888	Cryptococcus neoformans	51.97	1.00e-72	267.00
IUUC-Cme-027315	Cyanidioschyzon merolae	34.42	7.00e-60	225.00
IUUC-Dre-028420	Danio rerio	75.95	0.00e+00	918.00
IUUC-Dno-030041	Dasypus novemcinctus	96.88	0.00e+00	1204.00
IUUC-Dor-031039	Dipodomys ordii	81.80	0.00e+00	647.00
IUUC-Dse-031504	Dothistroma septosporum	35.53	3.00e-94	339.00
IUUC-Dme-031771	Drosophila melanogaster	50.08	4.00e-148	518.00
IUUC-Ete-033037	Echinops telfairi	91.09	0.00e+00	1080.00
IUUC-Eca-033774	Equus caballus	97.81	0.00e+00	1208.00
IUUC-Eeu-035074	Erinaceus europaeus	96.92	0.00e+00	972.00
IUUC-Fca-036508	Felis catus	97.98	0.00e+00	1210.00
IUUC-Fal-036813	Ficedula albicollis	86.82	0.00e+00	1021.00
IUUC-Fox-038056	Fusarium oxysporum	43.95	5.00e-106	378.00
IUUC-Fso-038223	Fusarium solani	42.70	2.00e-104	372.00
IUUC-Gmo-038526	Gadus morhua	75.04	0.00e+00	899.00
IUUC-Ggr-039767	Gaeumannomyces graminis	44.12	2.00e-101	363.00
IUUC-Gga-040981	Gallus gallus	87.97	0.00e+00	1053.00
IUUC-Gac-041437	Gasterosteus aculeatus	76.18	0.00e+00	926.00
IUUC-Gma-044072	Glycine max	37.82	3.00e-114	405.00
IUUC-Ggo-045358	Gorilla gorilla	95.98	0.00e+00	1132.00
IUUC-Hsa-046068	Homo sapiens	99.53	0.00e+00	1192.00
IUUC-Hvu-047646	Hordeum vulgare	37.93	7.00e-108	384.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	97.19	0.00e+00	1200.00
IUUC-Lch-049565	Latimeria chalumnae	81.49	0.00e+00	1043.00
IUUC-Lpe-050884	Leersia perrieri	40.82	5.00e-109	388.00
IUUC-Loc-052493	Lepisosteus oculatus	81.75	0.00e+00	1026.00
IUUC-Lma-053117	Leptosphaeria maculans	44.28	1.00e-101	363.00
IUUC-Laf-054518	Loxodonta africana	93.92	0.00e+00	1180.00
IUUC-Mor-057137	Magnaporthe oryzae	43.33	9.00e-96	344.00
IUUC-Mpo-057449	Magnaporthe poae	42.51	4.00e-102	365.00
IUUC-Mtr-058045	Medicago truncatula	39.41	3.00e-118	419.00
IUUC-Mla-058864	Melampsora laricipopulina	45.72	3.00e-96	345.00
IUUC-Mga-059422	Meleagris gallopavo	83.03	0.00e+00	932.00
IUUC-Mvi-060536	Microbotryum violaceum	42.62	2.00e-87	316.00
IUUC-Mmr-061161	Microcebus murinus	96.17	0.00e+00	1206.00
IUUC-Mdo-061802	Monodelphis domestica	93.14	0.00e+00	1142.00
IUUC-Mmu-064357	Mus musculus	94.38	0.00e+00	1196.00
IUUC-Mac-065475	Musa acuminata	38.69	1.00e-110	393.00
IUUC-Mpu-066895	Mustela putorius furo	97.81	0.00e+00	1253.00
IUUC-Mlu-067862	Myotis lucifugus	96.88	0.00e+00	1245.00
IUUC-Nfi-068385	Neosartorya fischeri	44.02	5.00e-110	391.00
IUUC-Ncr-068885	Neurospora crassa	41.88	3.00e-107	382.00
IUUC-Nle-069524	Nomascus leucogenys	98.75	0.00e+00	1174.00
IUUC-Opr-071038	Ochotona princeps	97.19	0.00e+00	1246.00
IUUC-Ont-071719	Oreochromis niloticus	76.27	0.00e+00	983.00
IUUC-Oan-072877	Ornithorhynchus anatinus	90.57	0.00e+00	994.00
IUUC-Ocu-074080	Oryctolagus cuniculus	97.03	0.00e+00	1200.00
IUUC-Oba-075936	Oryza barthii	38.13	7.00e-110	391.00
IUUC-Obr-076841	Oryza brachyantha	38.45	7.00e-112	397.00
IUUC-Ogl-077686	Oryza glaberrima	38.18	2.00e-111	396.00
IUUC-Ogu-078597	Oryza glumaepatula	37.25	7.00e-107	381.00
IUUC-Oin-079791	Oryza indica	38.13	7.00e-110	391.00
IUUC-Olo-081009	Oryza longistaminata	38.13	9.00e-110	390.00
IUUC-Ome-081327	Oryza meridionalis	35.65	3.00e-104	372.00
IUUC-Oni-082334	Oryza nivara	37.42	2.00e-107	382.00
IUUC-Opu-083447	Oryza punctata	38.45	2.00e-111	396.00
IUUC-Oru-084977	Oryza rufipogon	38.13	3.00e-109	389.00
IUUC-Osa-086160	Oryza sativa	43.98	4.00e-96	345.00
IUUC-Ola-087415	Oryzias latipes	75.83	0.00e+00	937.00
IUUC-Olu-087850	Ostreococcus lucimarinus	40.22	7.00e-101	360.00
IUUC-Oga-088434	Otolemur garnettii	97.66	0.00e+00	1213.00
IUUC-Oar-089872	Ovis aries	96.97	0.00e+00	1196.00
IUUC-Ptr-091212	Pan troglodytes	99.53	0.00e+00	1192.00
IUUC-Pan-092708	Papio anubis	99.61	6.00e-133	467.00
IUUC-Psi-093703	Pelodiscus sinensis	90.91	0.00e+00	1053.00
IUUC-Pno-094953	Phaeosphaeria nodorum	46.06	6.00e-106	378.00
IUUC-Ppa-095963	Physcomitrella patens	44.22	2.00e-108	386.00
IUUC-Pfo-097515	Poecilia formosa	75.04	0.00e+00	932.00
IUUC-Pab-097951	Pongo abelii	99.26	0.00e+00	1035.00
IUUC-Pop-099703	Populus trichocarpa	36.63	5.00e-96	345.00
IUUC-Pca-100426	Procavia capensis	94.69	0.00e+00	1209.00
IUUC-Ppe-101152	Prunus persica	39.05	2.00e-112	399.00
IUUC-Pva-102792	Pteropus vampyrus	92.93	0.00e+00	1157.00
IUUC-Pgr-103592	Puccinia graminis	39.18	3.00e-101	362.00
IUUC-Ptt-103805	Puccinia triticina	41.92	6.00e-87	315.00
IUUC-Pte-104215	Pyrenophora teres	44.56	9.00e-113	400.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	46.24	5.00e-111	395.00
IUUC-Rno-106117	Rattus norvegicus	94.53	0.00e+00	1201.00
IUUC-Sce-106177	Saccharomyces cerevisiae	34.37	5.00e-77	282.00
IUUC-Sha-107006	Sarcophilus harrisii	93.15	0.00e+00	1149.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.96	1.00e-94	340.00
IUUC-Spo-108020	Schizosaccharomyces pombe	44.38	7.00e-96	344.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	43.64	4.00e-104	372.00
IUUC-Smo-109264	Selaginella moellendorffii	43.75	1.00e-107	383.00
IUUC-Sit-110581	Setaria italica	40.84	1.00e-109	390.00
IUUC-Sly-111870	Solanum lycopersicum	39.41	1.00e-111	397.00
IUUC-Stu-112283	Solanum tuberosum	39.54	6.00e-109	388.00
IUUC-Sar-113432	Sorex araneus	72.23	0.00e+00	797.00
IUUC-Sbi-114075	Sorghum bicolor	38.44	1.00e-110	393.00
IUUC-Sre-114926	Sporisorium reilianum	43.22	2.00e-104	373.00
IUUC-Ssc-116281	Sus scrofa	98.62	4.00e-118	416.00
IUUC-Tgu-117247	Taeniopygia guttata	85.71	0.00e+00	1019.00
IUUC-Tru-118075	Takifugu rubripes	71.16	0.00e+00	894.00
IUUC-Tsy-119398	Tarsius syrichta	81.41	0.00e+00	932.00
IUUC-Tni-120771	Tetraodon nigroviridis	65.95	0.00e+00	807.00
IUUC-Tca-121651	Theobroma cacao	39.52	7.00e-111	394.00
IUUC-Tre-122224	Trichoderma reesei	43.58	2.00e-96	346.00
IUUC-Tvi-122634	Trichoderma virens	43.40	3.00e-96	345.00
IUUC-Tae-125665	Triticum aestivum	40.75	1.00e-105	376.00
IUUC-Tur-126417	Triticum urartu	38.07	1.00e-106	380.00
IUUC-Tme-127016	Tuber melanosporum	44.59	4.00e-97	348.00
IUUC-Tbe-127678	Tupaia belangeri	81.72	2.00e-178	618.00
IUUC-Ttr-128598	Tursiops truncatus	93.59	0.00e+00	1189.00
IUUC-Uma-129612	Ustilago maydis	41.94	3.00e-97	349.00
IUUC-Vda-129811	Verticillium dahliae	43.52	6.00e-102	364.00
IUUC-Vpa-130732	Vicugna pacos	83.59	0.00e+00	1033.00
IUUC-Vvi-130832	Vitis vinifera	42.17	5.00e-107	381.00
IUUC-Xtr-132823	Xenopus tropicalis	76.46	0.00e+00	926.00
IUUC-Xma-133552	Xiphophorus maculatus	74.88	0.00e+00	931.00
IUUC-Yli-134666	Yarrowia lipolytica	37.66	4.00e-76	278.00
IUUC-Zma-135547	Zea mays	38.67	3.00e-109	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence