iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047394

Ensembl Protein ID

MLOC_3103.1

UniProt Accession

M0VJ70; M0VJ70_HORVV

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_3103	MLOC_3103.1	MLOC_3103.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	34.33	3.00e-28	122.00	IUUC-Ath-007187

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Hordeum vulgare

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MNGSSSNKRS AEAIREGDTW MDVRILKETL DCTICFEHLT TEIYQCSVGH FVCSSCRDKI 60
LDKKCPTCSI KTSFNRCFGM EHVVQSVAFP CSNAKYGCRE GHTYYQKERH EQVCTYAPCF 120

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Nucleotide Sequence
(Fasta)

CCCGCTCCCT CCTCTCAAAC CCAAACCCAA ACCCTTGCCG CCGTCGCCGG CGCTCCCGCT 60
TCCTCCTCCG CCCCGCTTCT CCCGCTCCCA CTGGCCTCGG ATCGACGAAC GCGCTGTCCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005653	Arabidopsis lyrata	34.63	6.00e-27	113.00
IUUC-Ath-007187	Arabidopsis thaliana	34.33	8.00e-30	122.00
IUUC-Bdi-014026	Brachypodium distachyon	50.18	8.00e-74	268.00
IUUC-Bol-016089	Brassica oleracea	33.47	4.00e-27	113.00
IUUC-Bra-016844	Brassica rapa	33.62	2.00e-24	105.00
IUUC-Mtr-058203	Medicago truncatula	34.62	4.00e-33	134.00
IUUC-Opu-083398	Oryza punctata	44.58	4.00e-40	158.00
IUUC-Tae-124152	Triticum aestivum	80.13	3.00e-136	476.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence