iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134279

Ensembl Protein ID

ENSXMAP00000019208.1

UniProt Accession

M4AXL3; M4AXL3_XIPMA

Genbank Protein ID

ENSXMAP00000019208

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01033964

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000019162.1	ENSXMAT00000019236.1	ENSXMAP00000019208.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	1.10e-143	478.1	170	472
E3 adaptor/Cullin RING/DCX/DWD	1.20e-27	94.9	305	343

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWs+ n l+v+Lg++vylwsa+t++v++l+dl  ++d+vtsv w e+g+l+avGt+kg v+i+D++  +k
   Q: 170  PFKVLDAPELQDDFYLNLVDWSAGNLLSVGLGACVYLWSACTSQVTRLCDLsVDGDSVTSVCWNERGSLVAVGTHKGYVQIWDAAGGRK 258
           689************************************************999*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfke 177
           +  l+ghsarvgaL+Wn e+lssGsrd+ il+rdvr++  + ++lq+h+qevCGlkw+ d+++LasGGnDn++ vw++ss  P++++++
   Q: 259  LTCLEGHSARVGALAWNGEQLSSGSRDRVILQRDVRTPPATERRLQGHRQEVCGLKWSPDHQHLASGGNDNKLLVWNSSSLVPVQQYSD 347
           ***************************************************************************************** PP
   S: 178  hkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgh 266
           h aavkaiawsP+q++lLasGGGtaDrc++fwntltg+ l++ dtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+gh
   Q: 348  HLAAVKAIAWSPHQHGLLASGGGTADRCLRFWNTLTGQALQSTDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGH 436
           ***************************************************************************************** PP
   S: 267  eaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           ++Rvl+la+spdgeaivt+agDetlrfw+lf+k++ 
   Q: 437  SYRVLYLAVSPDGEAIVTGAGDETLRFWNLFSKTRC 472
           ********************************9875 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH  +v++l++ +d  +l+sG++D+++ vW+ ++ v+++
   Q: 305  GHRQEVCGLKWsPDhQHLASGGNDNKLLVWNSSSLVPVQ 343
           8***********999****************88888776 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MDQEYERRLL RQINHQNLHT ERRMTKSLGA ACSPLSVKSG DRFIPTRAGS NWSINFHYAN 60
ENCHSPAQNH KAKDAGSDSS KDAVAYAALL RNELLGAGIE TVAEPHADDR RHEVLAPDSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAAGCGCAC AGCACAGACA GCAGAAGTAC AAGCTACAAA GCAAAAAAAA AAAAAAAAAA 60
AAAATTAACT AGCCACAGCT GACTCCGGAC GCCATCTTTG TCGCGAACAT AAACAACATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

xma:102225050

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011773	Astyanax mexicanus	90.35	0.00e+00	907.00
IUUC-Dre-027860	Danio rerio	91.17	0.00e+00	912.00
IUUC-Fox-037814	Fusarium oxysporum	64.49	1.00e-123	436.00
IUUC-Gmo-039431	Gadus morhua	87.06	0.00e+00	879.00
IUUC-Gac-041566	Gasterosteus aculeatus	91.99	0.00e+00	884.00
IUUC-Loc-052240	Lepisosteus oculatus	85.83	0.00e+00	863.00
IUUC-Ont-071725	Oreochromis niloticus	93.84	0.00e+00	944.00
IUUC-Ola-086983	Oryzias latipes	92.48	0.00e+00	933.00
IUUC-Pfo-096991	Poecilia formosa	98.77	0.00e+00	954.00
IUUC-Sit-110550	Setaria italica	52.81	2.00e-127	448.00
IUUC-Tru-118528	Takifugu rubripes	90.87	0.00e+00	872.00
IUUC-Tni-120312	Tetraodon nigroviridis	91.39	0.00e+00	871.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence