iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000005962.1	ENSCJAT00000011831.1	ENSCJAP00000011210.1
ENSCJAG00000005962.1	ENSCJAT00000011848.1	ENSCJAP00000011228.1
ENSCJAG00000005962.1	ENSCJAT00000011862.1	ENSCJAP00000011241.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.90e-73	246.9	89	418
ULD/UDP/UBQ/UBQ_Other	1.80e-10	41.5	959	1021

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenp........kepkgellkslqklfeelwkskkkavsprel 73
           +Gl+Nlg+tCY+N  LQ+ +   elr++l          +                  + + ++++++lq lf+ l++s++++++p+ +
   Q: 89   VGLTNLGATCYVNTFLQVWFLNLELRQALYLcpstcsdyR---------LgdgiqtekDYEPQTICEHLQYLFALLQNSNRRYIDPSGF 168
           6*****************************9555554443.........24444433367888************************** PP
   S: 74   lkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnv 162
           +kal+     +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++
   Q: 169  VKALG-----LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRE 229
           ****9.....78899*******************.......................457889999*********************** PP
   S: 163  ssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekink 251
           s+  ++f++l+l+++g++     +l+dc+++f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+
   Q: 230  SKLLSKFYELELNIQGHK-----QLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNT 313
           ******************.....9***************************************************************** PP
   S: 252  kvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg........... 327
           ++ f + Ld++p+++++      ++ YeL+av++H G s+ sGHY+a+vk+ ++g+W++f+D+ +++++ ++ +   +           
   Q: 314  YIGFSEILDMEPYVEHKGG----SYVYELSAVLIHRGvSAYSGHYIAHVKDpQSGEWYKFNDEDIEKMEGKKLQLGIEedlepsksqtr 398
           **************99554....79**************************44555************9999998655899******** PP
   S: 328  ...........staYvlfYk 336
                      ++aY+l+Y+
   Q: 399  kpkcgkgthcsRNAYMLVYR 418
           *******************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++GkiL +d+ tL+ +g+ ++s+i+l  +++
   Q: 959  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILsDDCATLGTLGVIPESVILLKADEP 1021
           344489999************************************************988775 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCKG NPNCLVGIGE 60
HIWLGEIDEN SFHNIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACGTCCGCG GGCGCTGGGG GTGTCGGGTG TAGGGTGTCC GCGGCGGCGC TTTGCGGCCG 60
GTCGTGCGGG TCGGGCGCGA GCGGGTGCGG CGGCAGTGGC GTGCACAGGT GATTGACTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	32.18	3.00e-80	293.00
IUUC-Aml-001357	Ailuropoda melanoleuca	96.57	0.00e+00	2036.00
IUUC-Atr-002976	Amborella trichopoda	31.85	4.00e-77	283.00
IUUC-Apl-003773	Anas platyrhynchos	86.58	0.00e+00	1677.00
IUUC-Aca-004466	Anolis carolinensis	80.87	0.00e+00	860.00
IUUC-Aly-006249	Arabidopsis lyrata	29.17	5.00e-71	263.00
IUUC-Ath-006700	Arabidopsis thaliana	30.12	1.00e-79	291.00
IUUC-Ame-011554	Astyanax mexicanus	67.63	0.00e+00	1435.00
IUUC-Bta-012573	Bos taurus	95.81	0.00e+00	2046.00
IUUC-Bdi-014149	Brachypodium distachyon	32.11	2.00e-81	297.00
IUUC-Bol-016289	Brassica oleracea	31.80	8.00e-77	282.00
IUUC-Bra-017494	Brassica rapa	31.67	6.00e-82	299.00
IUUC-Cel-018662	Caenorhabditis elegans	27.65	1.00e-28	122.00
IUUC-Cfa-020294	Canis familiaris	96.86	0.00e+00	2084.00
IUUC-Cpo-021706	Cavia porcellus	93.84	0.00e+00	1927.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	35.34	6.00e-43	171.00
IUUC-Csa-023931	Chlorocebus sabaeus	97.52	0.00e+00	2079.00
IUUC-Cho-024566	Choloepus hoffmanni	97.47	2.00e-160	560.00
IUUC-Cin-025307	Ciona intestinalis	47.49	6.00e-76	276.00
IUUC-Csv-026006	Ciona savignyi	37.12	3.00e-149	523.00
IUUC-Cne-027065	Cryptococcus neoformans	28.43	6.00e-68	253.00
IUUC-Dre-027624	Danio rerio	68.39	0.00e+00	1483.00
IUUC-Dno-029633	Dasypus novemcinctus	95.89	0.00e+00	1303.00
IUUC-Dor-030809	Dipodomys ordii	97.88	0.00e+00	686.00
IUUC-Ete-032818	Echinops telfairi	91.11	0.00e+00	946.00
IUUC-Eca-033692	Equus caballus	97.33	0.00e+00	2075.00
IUUC-Eeu-035185	Erinaceus europaeus	72.79	0.00e+00	794.00
IUUC-Fca-035676	Felis catus	96.47	0.00e+00	2075.00
IUUC-Fal-036913	Ficedula albicollis	85.63	0.00e+00	1817.00
IUUC-Gmo-038532	Gadus morhua	64.41	0.00e+00	1378.00
IUUC-Gga-041041	Gallus gallus	85.82	0.00e+00	1813.00
IUUC-Gac-042570	Gasterosteus aculeatus	65.26	0.00e+00	1415.00
IUUC-Gma-044034	Glycine max	26.74	7.00e-83	302.00
IUUC-Ggo-045367	Gorilla gorilla	92.49	0.00e+00	1939.00
IUUC-Hsa-046019	Homo sapiens	97.43	0.00e+00	2081.00
IUUC-Hvu-047303	Hordeum vulgare	33.58	3.00e-65	243.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	94.11	0.00e+00	2041.00
IUUC-Lch-049989	Latimeria chalumnae	75.21	0.00e+00	1626.00
IUUC-Lpe-051612	Leersia perrieri	32.59	3.00e-79	290.00
IUUC-Loc-052756	Lepisosteus oculatus	69.96	0.00e+00	1537.00
IUUC-Laf-054043	Loxodonta africana	95.32	0.00e+00	2055.00
IUUC-Mcc-054986	Macaca mulatta	97.81	0.00e+00	2091.00
IUUC-Meu-056228	Macropus eugenii	94.20	0.00e+00	687.00
IUUC-Mtr-058762	Medicago truncatula	29.37	2.00e-86	314.00
IUUC-Mga-059896	Meleagris gallopavo	85.22	0.00e+00	1712.00
IUUC-Mvi-060269	Microbotryum violaceum	37.18	1.00e-61	232.00
IUUC-Mmr-060887	Microcebus murinus	96.86	0.00e+00	2065.00
IUUC-Mdo-062506	Monodelphis domestica	91.90	0.00e+00	1972.00
IUUC-Mmu-063642	Mus musculus	91.75	0.00e+00	2001.00
IUUC-Mac-064896	Musa acuminata	31.64	6.00e-78	286.00
IUUC-Mpu-066194	Mustela putorius furo	96.48	0.00e+00	2056.00
IUUC-Mlu-067233	Myotis lucifugus	95.74	0.00e+00	2048.00
IUUC-Nle-069052	Nomascus leucogenys	98.28	0.00e+00	2102.00
IUUC-Opr-070890	Ochotona princeps	94.60	0.00e+00	1244.00
IUUC-Ont-071450	Oreochromis niloticus	64.39	0.00e+00	1357.00
IUUC-Oan-073252	Ornithorhynchus anatinus	87.98	0.00e+00	1051.00
IUUC-Ocu-073796	Oryctolagus cuniculus	95.55	0.00e+00	1753.00
IUUC-Oba-075563	Oryza barthii	32.03	9.00e-81	295.00
IUUC-Obr-076394	Oryza brachyantha	32.23	3.00e-81	296.00
IUUC-Ogl-077339	Oryza glaberrima	38.44	6.00e-41	160.00
IUUC-Ogu-079007	Oryza glumaepatula	32.69	3.00e-73	270.00
IUUC-Oin-079997	Oryza indica	32.03	4.00e-81	296.00
IUUC-Olo-080364	Oryza longistaminata	32.03	8.00e-81	295.00
IUUC-Ome-081165	Oryza meridionalis	32.70	6.00e-74	272.00
IUUC-Oni-083026	Oryza nivara	32.03	5.00e-81	296.00
IUUC-Opu-083284	Oryza punctata	33.75	6.00e-74	272.00
IUUC-Oru-084797	Oryza rufipogon	32.03	5.00e-81	296.00
IUUC-Osa-086221	Oryza sativa	38.44	6.00e-41	160.00
IUUC-Ola-086568	Oryzias latipes	65.41	0.00e+00	1416.00
IUUC-Oga-088687	Otolemur garnettii	97.24	0.00e+00	2073.00
IUUC-Oar-090345	Ovis aries	95.92	0.00e+00	1952.00
IUUC-Ptr-090734	Pan troglodytes	97.62	0.00e+00	2084.00
IUUC-Pan-091704	Papio anubis	93.93	0.00e+00	1985.00
IUUC-Psi-092937	Pelodiscus sinensis	86.02	0.00e+00	1592.00
IUUC-Ppa-095808	Physcomitrella patens	30.26	2.00e-67	251.00
IUUC-Pab-098129	Pongo abelii	97.52	0.00e+00	2081.00
IUUC-Pop-099738	Populus trichocarpa	31.72	2.00e-77	284.00
IUUC-Pca-100647	Procavia capensis	97.88	0.00e+00	686.00
IUUC-Ppe-102091	Prunus persica	32.77	7.00e-82	299.00
IUUC-Pva-102719	Pteropus vampyrus	96.19	0.00e+00	2045.00
IUUC-Rno-105363	Rattus norvegicus	93.24	0.00e+00	2015.00
IUUC-Sha-107620	Sarcophilus harrisii	89.86	0.00e+00	1850.00
IUUC-Smo-109487	Selaginella moellendorffii	27.68	6.00e-82	299.00
IUUC-Sit-110683	Setaria italica	33.12	9.00e-81	295.00
IUUC-Sly-111377	Solanum lycopersicum	31.16	7.00e-79	289.00
IUUC-Stu-111969	Solanum tuberosum	31.92	3.00e-69	256.00
IUUC-Sar-113099	Sorex araneus	94.74	0.00e+00	1721.00
IUUC-Sbi-113833	Sorghum bicolor	42.14	1.00e-56	213.00
IUUC-Ssc-115279	Sus scrofa	91.52	0.00e+00	1370.00
IUUC-Tgu-117519	Taeniopygia guttata	83.33	0.00e+00	1667.00
IUUC-Tru-117651	Takifugu rubripes	64.78	0.00e+00	1404.00
IUUC-Tsy-119201	Tarsius syrichta	93.13	0.00e+00	1810.00
IUUC-Tni-120840	Tetraodon nigroviridis	65.86	0.00e+00	1427.00
IUUC-Tca-121674	Theobroma cacao	31.45	5.00e-84	306.00
IUUC-Tae-125814	Triticum aestivum	32.75	1.00e-80	295.00
IUUC-Tur-126599	Triticum urartu	32.18	9.00e-80	292.00
IUUC-Tbe-127782	Tupaia belangeri	88.70	0.00e+00	1168.00
IUUC-Ttr-128312	Tursiops truncatus	95.43	0.00e+00	2026.00
IUUC-Vpa-130348	Vicugna pacos	96.32	0.00e+00	1959.00
IUUC-Vvi-131353	Vitis vinifera	32.52	1.00e-82	301.00
IUUC-Xtr-132172	Xenopus tropicalis	69.75	0.00e+00	1348.00
IUUC-Xma-133263	Xiphophorus maculatus	66.57	0.00e+00	1386.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence