iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Osa-086291

UUCD1 version

UUC-OrS-01432

Ensembl Protein ID

OS02T0261100-01

UniProt Accession

Q8S919; A0A0P0VHC2; UBC5B_ORYSJ

Genbank Protein ID

BAB89355.1; BAD20047.1; BAF08400.1; BAS77989.1; EAZ22486.1; BAH00395.1

Protein Name

Ubiquitin-conjugating enzyme E2 5B; E2 ubiquitin-conjugating enzyme 5B; Ubiquitin carrier protein 5b; Ubiquitin-protein ligase 5B

Genbank Nucleotide ID

AB074412; AP005777; AP008208; AP014958; CM000139; AK121248

Gene Name

UBC5B; Os02g0261100; LOC_Os02g16040; OsJ_06152; OSJNBb0026F09.5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OS02G0261100	OS02T0261100-01	OS02T0261100-01

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	16186120

Classification

Family	E-value	Score	Start	End
E2/UBC	3.00e-55	186.7	5	139
UBD/UBC-like/UBD_UBC	3.80e-73	245.0	5	142

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWsp 94
           R+ kelk+l+kdpp+++sa+pv e d+++w+++++Gp+d+pY+ggvF ++i+fp+dYPfkPPkv + tk+fhPn+++nG++Cl+ilk  e+Wsp
   Q: 5    RILKELKDLQKDPPTSCSAGPVAE-DMFHWQATLMGPSDSPYAGGVFLVTIHFPPDYPFKPPKVALKTKVFHPNINSNGSICLDILK--EQWSP 95
           899*********************.9************************************************************9..***** PP
   S: 95   alsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           al++++vllsi+sll++pnp++pl  e+a+++k++r++y++++r
   Q: 96   ALTISKVLLSICSLLTDPNPDDPLVPEIAHMYKTDRAKYESTAR 139
           ****************************************9987 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaalt 94
           ri kelkdl++d+++ +sa++v +d+f+++at++gp+dspy ggvf +ti++p dypfkppkva+ tk++hpninsngsicldil++qws+alt
   Q: 5    RILKELKDLQKDPPTSCSAGPVAEDMFHWQATLMGPSDSPYAGGVFLVTIHFPPDYPFKPPKVALKTKVFHPNINSNGSICLDILKEQWSPALT 98
           899******************************************************************************************* PP
   S: 95   lskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           +skvlls+csll+d++pddplv+eia++yktd+ ky+ +ar wt
   Q: 99   ISKVLLSICSLLTDPNPDDPLVPEIAHMYKTDRAKYESTARSWT 142
           *******************************************8 PP

Organism

Oryza sativa

Functional Description
(View)

E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.

Protein Sequence
(Fasta)

MASKRILKEL KDLQKDPPTS CSAGPVAEDM FHWQATLMGP SDSPYAGGVF LVTIHFPPDY 60
PFKPPKVALK TKVFHPNINS NGSICLDILK EQWSPALTIS KVLLSICSLL TDPNPDDPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATTCGGA GAGAGCTACT CCTCGTCGTT AGCCATGGCG TCCAAGCGGA TCCTCAAGGA 60
GCTCAAGGAC CTGCAGAAGG ATCCCCCCAC CTCCTGCAGC GCCGGTGAGA TGCATATCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0016567--P:protein ubiquitination

KEGG

osa:4328940

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002861	Amborella trichopoda	95.95	1.00e-83	300.00
IUUC-Aly-006364	Arabidopsis lyrata	96.62	2.00e-84	302.00
IUUC-Ath-007647	Arabidopsis thaliana	95.95	2.00e-83	299.00
IUUC-Bdi-014712	Brachypodium distachyon	95.27	1.00e-83	300.00
IUUC-Bol-016243	Brassica oleracea	95.95	2.00e-83	299.00
IUUC-Bra-016748	Brassica rapa	94.59	7.00e-84	303.00
IUUC-Lpe-050972	Leersia perrieri	98.65	5.00e-85	305.00
IUUC-Mtr-058532	Medicago truncatula	95.27	2.00e-83	300.00
IUUC-Obr-076658	Oryza brachyantha	98.65	5.00e-85	305.00
IUUC-Ogl-077124	Oryza glaberrima	99.32	2.00e-85	306.00
IUUC-Oin-080092	Oryza indica	99.32	2.00e-85	306.00
IUUC-Opu-083833	Oryza punctata	99.32	2.00e-85	306.00
IUUC-Ppa-095442	Physcomitrella patens	96.62	1.00e-83	300.00
IUUC-Ppe-101387	Prunus persica	97.30	4.00e-84	301.00
IUUC-Ptt-103723	Puccinia triticina	77.14	1.00e-62	231.00
IUUC-Smo-109317	Selaginella moellendorffii	95.95	2.00e-83	299.00
IUUC-Sly-110885	Solanum lycopersicum	96.62	5.00e-84	301.00
IUUC-Stu-111944	Solanum tuberosum	96.62	5.00e-84	301.00
IUUC-Sbi-114213	Sorghum bicolor	95.95	1.00e-83	300.00
IUUC-Tca-121413	Theobroma cacao	96.62	1.00e-83	300.00
IUUC-Tae-123745	Triticum aestivum	95.95	5.00e-84	301.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence