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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064180
UUCD1 version UUC-MuM-00352
Ensembl Protein ID ENSMUSP00000023217.9
UniProt Accession P97452; Q3TK87; Q6ZQI9; Q91X31; BOP1_MOUSE
Genbank Protein ID AAB19223.1; BAC97868.1; BAC37708.1; BAE39258.1; AAH12693.1; AAC80429.1
Protein Name Ribosome biogenesis protein BOP1; Block of proliferation 1 protein
Genbank Nucleotide ID U77415; AK129058; AK079627; AK167110; BC012693; AF061503
Gene Name Bop1; Kiaa0124
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022557.10 ENSMUST00000023217.9 ENSMUSP00000023217.9
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IIDPINAHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.40e-21 74.3 397 436
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+d v+cl+  ++   l+sGsdDgt+k+W++ t ++ k+
   Q: 397  GHSDLVRCLSVsPGgQWLASGSDDGTLKLWEVATARCMKT 436
           8**********988899*******************9875 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
 Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
MAGACGKPHM SPASLPGKRR LEPDQELQIQ EPPLLSDPDS SLSDSEESVF SGLEDLGSDS 60
SEEDTEGVAG SSGDEDNHRA EETSEELAQA APLCSRTEEA GALAQDEYEE DSSDEEDIRN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064180|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCCCGCTGC CGGAAGCGGC AGTAGATCGG TAGCCGGCGC GGCGCAGCAT GGCGGGGGCG 60
TGTGGTAAGC CCCACATGTC ACCGGCATCG CTGCCGGGGA AACGACGTTT GGAACCTGAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064180|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR028598--BOP1/Erb1
IPR012953--BOP1_N_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08145--BOP1NT
PF00400--WD40
SMART

SM01035--BOP1NT
SM00320--WD40
Gene Ontology

GO:0030529--C:intracellular ribonucleoprotein complex
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0003723--F:RNA binding
GO:0008283--P:cell proliferation
GO:0000448--P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0051726--P:regulation of cell cycle
GO:0042273--P:ribosomal large subunit biogenesis
GO:0006364--P:rRNA processing
KEGG mmu:12181
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001158 Aegilops tauschii 41.03 4.00e-123 435.00
IUUC-Aml-001507 Ailuropoda melanoleuca 79.94 0.00e+00 1036.00
IUUC-Atr-003141 Amborella trichopoda 41.78 2.00e-88 319.00
IUUC-Apl-003545 Anas platyrhynchos 66.26 0.00e+00 797.00
IUUC-Aly-005649 Arabidopsis lyrata 44.55 2.00e-157 549.00
IUUC-Ath-007625 Arabidopsis thaliana 44.97 5.00e-156 545.00
IUUC-Ago-007958 Ashbya gossypii 43.08 2.00e-159 556.00
IUUC-Acl-008344 Aspergillus clavatus 43.72 4.00e-144 505.00
IUUC-Afl-008616 Aspergillus flavus 43.43 6.00e-147 514.00
IUUC-Afu-009083 Aspergillus fumigatus 44.81 1.00e-142 500.00
IUUC-Ani-009365 Aspergillus nidulans 44.03 3.00e-147 516.00
IUUC-Ang-009796 Aspergillus niger 43.57 5.00e-142 498.00
IUUC-Aor-010015 Aspergillus oryzae 43.43 6.00e-147 514.00
IUUC-Ate-010537 Aspergillus terreus 44.57 3.00e-149 522.00
IUUC-Ame-011767 Astyanax mexicanus 69.55 1.00e-115 409.00
IUUC-Bgr-012286 Blumeria graminis 42.65 1.00e-148 520.00
IUUC-Bta-013569 Bos taurus 83.36 0.00e+00 1088.00
IUUC-Bci-013820 Botrytis cinerea 42.09 4.00e-141 495.00
IUUC-Bdi-014895 Brachypodium distachyon 45.72 1.00e-156 546.00
IUUC-Bol-016099 Brassica oleracea 44.25 1.00e-157 550.00
IUUC-Bra-017174 Brassica rapa 44.08 2.00e-157 550.00
IUUC-Cel-018201 Caenorhabditis elegans 46.87 4.00e-156 545.00
IUUC-Cja-019009 Callithrix jacchus 75.99 0.00e+00 955.00
IUUC-Cfa-020173 Canis familiaris 80.83 0.00e+00 1004.00
IUUC-Cpo-021796 Cavia porcellus 88.69 0.00e+00 1104.00
IUUC-Cre-022650 Chlamydomonas reinhardtii 47.45 2.00e-153 536.00
IUUC-Csa-023440 Chlorocebus sabaeus 87.88 0.00e+00 1146.00
IUUC-Cin-025782 Ciona intestinalis 54.91 0.00e+00 753.00
IUUC-Csv-026352 Ciona savignyi 55.61 0.00e+00 737.00
IUUC-Cgl-026393 Colletotrichum gloeosporioides 38.57 3.00e-114 405.00
IUUC-Cne-027004 Cryptococcus neoformans 44.43 2.00e-168 586.00
IUUC-Cme-027242 Cyanidioschyzon merolae 39.47 3.00e-125 442.00
IUUC-Dre-028658 Danio rerio 73.54 0.00e+00 983.00
IUUC-Dno-028883 Dasypus novemcinctus 85.37 0.00e+00 1063.00
IUUC-Dor-031031 Dipodomys ordii 88.34 0.00e+00 1137.00
IUUC-Dse-031443 Dothistroma septosporum 40.40 1.00e-143 503.00
IUUC-Dme-031786 Drosophila melanogaster 53.90 0.00e+00 731.00
IUUC-Eca-033677 Equus caballus 85.84 0.00e+00 1129.00
IUUC-Eeu-035310 Erinaceus europaeus 84.66 0.00e+00 915.00
IUUC-Fca-035888 Felis catus 83.57 0.00e+00 1073.00
IUUC-Fal-037438 Ficedula albicollis 67.43 0.00e+00 737.00
IUUC-Fox-037973 Fusarium oxysporum 44.23 5.00e-158 551.00
IUUC-Fso-038187 Fusarium solani 43.76 2.00e-157 549.00
IUUC-Gmo-039114 Gadus morhua 65.32 0.00e+00 838.00
IUUC-Ggr-039746 Gaeumannomyces graminis 42.16 9.00e-154 537.00
IUUC-Gga-040631 Gallus gallus 74.04 6.00e-160 556.00
IUUC-Gac-042582 Gasterosteus aculeatus 65.65 0.00e+00 879.00
IUUC-Gma-044215 Glycine max 45.16 6.00e-150 524.00
IUUC-Ggo-045587 Gorilla gorilla 90.08 0.00e+00 1139.00
IUUC-Hsa-046319 Homo sapiens 88.34 0.00e+00 1155.00
IUUC-Hvu-047526 Hordeum vulgare 44.66 2.00e-148 519.00
IUUC-Itr-048683 Ictidomys tridecemlineatus 90.08 0.00e+00 1134.00
IUUC-Kpa-049221 Komagataella pastoris 42.79 5.00e-153 535.00
IUUC-Lch-049640 Latimeria chalumnae 73.17 0.00e+00 990.00
IUUC-Lpe-051135 Leersia perrieri 42.63 2.00e-135 476.00
IUUC-Loc-051930 Lepisosteus oculatus 72.03 0.00e+00 974.00
IUUC-Lma-053290 Leptosphaeria maculans 43.29 2.00e-145 509.00
IUUC-Laf-053903 Loxodonta africana 81.01 0.00e+00 977.00
IUUC-Mcc-055471 Macaca mulatta 86.95 0.00e+00 1145.00
IUUC-Meu-056190 Macropus eugenii 83.41 0.00e+00 1049.00
IUUC-Mor-057135 Magnaporthe oryzae 42.61 3.00e-146 512.00
IUUC-Mpo-057475 Magnaporthe poae 42.36 1.00e-142 500.00
IUUC-Mtr-058689 Medicago truncatula 41.52 2.00e-133 469.00
IUUC-Mla-059149 Melampsora laricipopulina 44.57 1.00e-166 580.00
IUUC-Mga-059645 Meleagris gallopavo 63.93 2.00e-100 358.00
IUUC-Mvi-060485 Microbotryum violaceum 45.16 1.00e-145 511.00
IUUC-Mmr-061674 Microcebus murinus 88.78 0.00e+00 1095.00
IUUC-Mdo-062973 Monodelphis domestica 78.51 0.00e+00 1065.00
IUUC-Mac-064535 Musa acuminata 39.12 9.00e-99 354.00
IUUC-Mpu-066406 Mustela putorius furo 81.40 0.00e+00 1112.00
IUUC-Mlu-067795 Myotis lucifugus 87.76 0.00e+00 1105.00
IUUC-Nfi-068516 Neosartorya fischeri 44.36 5.00e-135 475.00
IUUC-Ncr-068767 Neurospora crassa 43.08 5.00e-138 484.00
IUUC-Opr-071084 Ochotona princeps 83.93 8.00e-141 493.00
IUUC-Ont-071614 Oreochromis niloticus 68.66 0.00e+00 920.00
IUUC-Oba-075980 Oryza barthii 42.67 9.00e-136 477.00
IUUC-Obr-076799 Oryza brachyantha 44.98 1.00e-150 526.00
IUUC-Ogl-077134 Oryza glaberrima 44.66 9.00e-146 510.00
IUUC-Ogu-078655 Oryza glumaepatula 43.37 5.00e-141 494.00
IUUC-Oin-079654 Oryza indica 44.66 1.00e-145 509.00
IUUC-Olo-080706 Oryza longistaminata 42.51 8.00e-137 481.00
IUUC-Ome-081716 Oryza meridionalis 39.19 7.00e-116 411.00
IUUC-Oni-082508 Oryza nivara 42.97 3.00e-137 482.00
IUUC-Opu-083707 Oryza punctata 42.51 5.00e-136 478.00
IUUC-Oru-084453 Oryza rufipogon 42.51 8.00e-137 481.00
IUUC-Osa-085811 Oryza sativa 44.66 9.00e-146 510.00
IUUC-Ola-087361 Oryzias latipes 69.35 0.00e+00 920.00
IUUC-Oga-088015 Otolemur garnettii 87.44 0.00e+00 1149.00
IUUC-Oar-090058 Ovis aries 89.88 7.00e-88 318.00
IUUC-Ptr-090631 Pan troglodytes 81.37 2.00e-139 488.00
IUUC-Pan-092306 Papio anubis 86.97 0.00e+00 1142.00
IUUC-Pma-094622 Petromyzon marinus 71.54 0.00e+00 963.00
IUUC-Pno-094794 Phaeosphaeria nodorum 40.13 1.00e-134 473.00
IUUC-Ppa-095528 Physcomitrella patens 43.53 2.00e-96 346.00
IUUC-Pfo-096682 Poecilia formosa 68.87 0.00e+00 927.00
IUUC-Pab-097939 Pongo abelii 89.17 0.00e+00 1026.00
IUUC-Pop-099530 Populus trichocarpa 45.29 4.00e-142 498.00
IUUC-Pca-100333 Procavia capensis 86.83 0.00e+00 1101.00
IUUC-Ppe-102078 Prunus persica 44.08 2.00e-150 526.00
IUUC-Pgr-103525 Puccinia graminis 45.61 1.00e-160 560.00
IUUC-Ptt-103929 Puccinia triticina 45.20 6.00e-156 545.00
IUUC-Pte-104029 Pyrenophora teres 42.81 4.00e-154 538.00
IUUC-Pyt-104446 Pyrenophora triticirepentis 42.97 2.00e-154 539.00
IUUC-Rno-105248 Rattus norvegicus 93.72 0.00e+00 1256.00
IUUC-Sce-106381 Saccharomyces cerevisiae 40.79 6.00e-154 538.00
IUUC-Sha-106519 Sarcophilus harrisii 83.09 0.00e+00 1066.00
IUUC-Sja-107908 Schizosaccharomyces japonicus 41.39 2.00e-141 496.00
IUUC-Spo-108071 Schizosaccharomyces pombe 41.26 1.00e-139 490.00
IUUC-Smo-109604 Selaginella moellendorffii 45.67 3.00e-155 541.00
IUUC-Sit-110551 Setaria italica 44.50 1.00e-148 520.00
IUUC-Sly-110970 Solanum lycopersicum 46.94 6.00e-83 301.00
IUUC-Stu-112593 Solanum tuberosum 46.02 3.00e-155 542.00
IUUC-Sar-113123 Sorex araneus 85.71 2.00e-148 518.00
IUUC-Sbi-113945 Sorghum bicolor 43.57 8.00e-152 530.00
IUUC-Sre-115188 Sporisorium reilianum 44.34 4.00e-156 545.00
IUUC-Ssc-115352 Sus scrofa 87.80 0.00e+00 1077.00
IUUC-Tru-117685 Takifugu rubripes 69.90 0.00e+00 933.00
IUUC-Tni-119982 Tetraodon nigroviridis 69.61 0.00e+00 896.00
IUUC-Tca-121664 Theobroma cacao 46.12 5.00e-158 551.00
IUUC-Tre-122229 Trichoderma reesei 43.55 2.00e-140 493.00
IUUC-Tvi-122576 Trichoderma virens 43.49 2.00e-143 503.00
IUUC-Tae-124110 Triticum aestivum 44.41 1.00e-138 486.00
IUUC-Tur-126781 Triticum urartu 41.36 1.00e-119 424.00
IUUC-Tme-127080 Tuber melanosporum 46.49 1.00e-171 596.00
IUUC-Ttr-128514 Tursiops truncatus 83.81 0.00e+00 763.00
IUUC-Uma-129556 Ustilago maydis 43.05 3.00e-150 526.00
IUUC-Vda-129715 Verticillium dahliae 43.85 6.00e-153 534.00
IUUC-Vvi-131211 Vitis vinifera 43.77 9.00e-146 510.00
IUUC-Xma-133883 Xiphophorus maculatus 68.82 0.00e+00 890.00
IUUC-Yli-134438 Yarrowia lipolytica 43.87 3.00e-146 512.00
IUUC-Zma-135341 Zea mays 41.86 1.00e-89 324.00
Created Date 25-Jun-2017

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