iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Meu-056727

Ensembl Protein ID

ENSMEUP00000010822.1

UniProt Accession

W8BYZ8; W8BYZ8_MACEU

Genbank Protein ID

JAC06641.1

Protein Name

HUWE1Y

Genbank Nucleotide ID

GATO01000005

Gene Name

HUWE1; HUWE1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMEUG00000011796.1	ENSMEUT00000011914.1	ENSMEUP00000010822.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	3.30e-08	33.1	1305	1342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           ++++l+ql++MGF+re+a +aL++   + e A+eyLl++
   Q: 1305 NQQQLQQLMDMGFTREHAMEALLN-TSTMEQATEYLLTH 1342
           89**********************.7***********98 PP

Organism

Macropus eugenii

Protein Sequence
(Fasta)

PADCRALIDK LKGCNDEQLL LELQQIKTWN IGKCELYHWV DLLDRFDGIL ADAGQTVENM 60
AWMLMCDVPD KEHLKLLLLA VLNFTALLIE YSFSRHLYSS IEHLTTLLAS SDMQVVLAVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGCAGACT GCCGAGCTCT GATAGACAAA CTTAAGGGTT GTAATGATGA GCAACTCCTC 60
TTGGAACTGC AGCAGATCAA AACCTGGAAT ATTGGAAAGG TGGGTAGGCT GGCATGGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR025527--DUF4414
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR004170--WWE-dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50918--WWE

Pfam

PF14377--DUF4414
PF06025--DUF913
PF00632--HECT
PF00627--UBA
PF02825--WWE

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001684	Ailuropoda melanoleuca	87.67	0.00e+00	1974.00
IUUC-Aca-005263	Anolis carolinensis	87.31	0.00e+00	1946.00
IUUC-Ame-011067	Astyanax mexicanus	85.71	0.00e+00	1778.00
IUUC-Bta-012813	Bos taurus	87.59	0.00e+00	2005.00
IUUC-Bol-015228	Brassica oleracea	22.19	5.00e-28	120.00
IUUC-Cja-018741	Callithrix jacchus	87.59	0.00e+00	1982.00
IUUC-Cfa-020083	Canis familiaris	87.67	0.00e+00	1980.00
IUUC-Cpo-021923	Cavia porcellus	86.74	0.00e+00	1971.00
IUUC-Csa-023853	Chlorocebus sabaeus	87.59	0.00e+00	1977.00
IUUC-Cho-024718	Choloepus hoffmanni	92.22	0.00e+00	653.00
IUUC-Cin-025627	Ciona intestinalis	53.48	0.00e+00	1066.00
IUUC-Csv-025824	Ciona savignyi	53.02	0.00e+00	1001.00
IUUC-Dre-028525	Danio rerio	85.77	0.00e+00	1770.00
IUUC-Dno-029680	Dasypus novemcinctus	86.67	0.00e+00	1961.00
IUUC-Dor-030902	Dipodomys ordii	90.13	0.00e+00	961.00
IUUC-Dme-032122	Drosophila melanogaster	45.79	5.00e-102	367.00
IUUC-Ete-032690	Echinops telfairi	78.32	0.00e+00	717.00
IUUC-Eca-033915	Equus caballus	87.22	0.00e+00	1975.00
IUUC-Eeu-034963	Erinaceus europaeus	94.13	0.00e+00	1916.00
IUUC-Fca-035824	Felis catus	87.90	0.00e+00	1985.00
IUUC-Gmo-039073	Gadus morhua	88.17	0.00e+00	1761.00
IUUC-Gac-042430	Gasterosteus aculeatus	88.17	0.00e+00	1774.00
IUUC-Ggo-044785	Gorilla gorilla	86.12	0.00e+00	2024.00
IUUC-Hsa-046879	Homo sapiens	87.74	0.00e+00	1982.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	79.81	0.00e+00	884.00
IUUC-Lch-050252	Latimeria chalumnae	80.70	0.00e+00	1853.00
IUUC-Loc-052472	Lepisosteus oculatus	84.63	0.00e+00	1769.00
IUUC-Laf-054154	Loxodonta africana	94.51	0.00e+00	1952.00
IUUC-Mcc-055085	Macaca mulatta	87.59	0.00e+00	1977.00
IUUC-Mmr-060820	Microcebus murinus	87.43	0.00e+00	1976.00
IUUC-Mdo-062930	Monodelphis domestica	92.73	0.00e+00	2126.00
IUUC-Mmu-063601	Mus musculus	87.28	0.00e+00	1955.00
IUUC-Mpu-066653	Mustela putorius furo	87.52	0.00e+00	1974.00
IUUC-Mlu-067418	Myotis lucifugus	87.21	0.00e+00	2026.00
IUUC-Nle-069418	Nomascus leucogenys	94.80	0.00e+00	1961.00
IUUC-Opr-070187	Ochotona princeps	86.44	8.00e-170	593.00
IUUC-Ont-071300	Oreochromis niloticus	88.30	0.00e+00	1773.00
IUUC-Oan-073046	Ornithorhynchus anatinus	86.84	0.00e+00	2133.00
IUUC-Ocu-074178	Oryctolagus cuniculus	85.62	0.00e+00	2041.00
IUUC-Osa-086016	Oryza sativa	25.05	3.00e-17	84.30
IUUC-Ola-087437	Oryzias latipes	86.57	0.00e+00	1153.00
IUUC-Olu-087645	Ostreococcus lucimarinus	22.33	9.00e-09	57.40
IUUC-Oga-088903	Otolemur garnettii	87.12	0.00e+00	1962.00
IUUC-Oar-090210	Ovis aries	87.43	0.00e+00	1975.00
IUUC-Ptr-090502	Pan troglodytes	86.19	0.00e+00	2027.00
IUUC-Pan-092368	Papio anubis	87.59	0.00e+00	1979.00
IUUC-Pma-094246	Petromyzon marinus	72.89	0.00e+00	775.00
IUUC-Pfo-096232	Poecilia formosa	85.12	0.00e+00	1788.00
IUUC-Pab-098583	Pongo abelii	87.67	0.00e+00	1978.00
IUUC-Pca-100310	Procavia capensis	80.42	0.00e+00	1588.00
IUUC-Pva-102116	Pteropus vampyrus	86.96	0.00e+00	1993.00
IUUC-Rno-105889	Rattus norvegicus	94.90	0.00e+00	1917.00
IUUC-Sha-106961	Sarcophilus harrisii	89.21	0.00e+00	2013.00
IUUC-Sar-113291	Sorex araneus	91.16	0.00e+00	1828.00
IUUC-Sre-115094	Sporisorium reilianum	26.23	1.00e-46	183.00
IUUC-Ssc-115754	Sus scrofa	87.59	0.00e+00	1977.00
IUUC-Tru-118570	Takifugu rubripes	88.80	0.00e+00	1809.00
IUUC-Tsy-119159	Tarsius syrichta	95.36	0.00e+00	1836.00
IUUC-Tni-120836	Tetraodon nigroviridis	73.29	0.00e+00	1705.00
IUUC-Tae-124731	Triticum aestivum	30.28	1.00e-13	72.00
IUUC-Tbe-127506	Tupaia belangeri	87.88	0.00e+00	1345.00
IUUC-Ttr-129253	Tursiops truncatus	91.00	0.00e+00	1608.00
IUUC-Uma-129331	Ustilago maydis	26.14	2.00e-42	169.00
IUUC-Vpa-130708	Vicugna pacos	91.82	0.00e+00	1871.00
IUUC-Vvi-131559	Vitis vinifera	25.99	1.00e-39	158.00
IUUC-Xtr-132123	Xenopus tropicalis	90.78	0.00e+00	1818.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence