iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Opu-083885

Ensembl Protein ID

OPUNC12G08800.1

UniProt Accession

A0A0E0MLR6; A0A0E0MLR6_ORYPU

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OPUNC12G08800	OPUNC12G08800.1	OPUNC12G08800.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-39	133.1	50	86
UBD/Beta-Prp	2.00e-77	261.2	3	322

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhaTQPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********6449********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           t +++++++++ + f+p +++++++  +g i+ wd+++g+ll ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++t  c+ tl+gh d++
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFTLHGHLDYI 96
           67889999************************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl......................... 166
           ++++f+ +  ++vs+s+d+tir+w++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                         
   Q: 97   RTVQFHHEYPWIVSASDDQTIRIWNWQSRTCVA-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddilrltqmntdlf 189
           *********************************.*************************************************97777777777 PP
   S: 167  ..ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
               + + + l+g h++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd ++++ 
   Q: 190  ggVDAVVKYVLEG-HDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRVWDATKRTG 282
           6444444444466.********************************777668****************************************** PP
   S: 257  lktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkne 298
           ++t+ +++++++  a+ +++ n l++g + +   ++kl++++
   Q: 283  IQTFRREHDRFWILAA-HPEMNLLAAGHD-NGMIVFKLERER 322
           ****************.888877777755.566677887766 PP

Organism

Oryza punctata

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GVIQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
ATQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHHEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACCA AGTTCGAGAC GAAGAGCAAC CGGGTGAAGG GGCTGAGCTT CCACCCGCGG 60
CGGCCATGGA TCCTGGCCAG CCTCCACAGC GGGGTGATCC AGATGTGGGA CTACCGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	93.76	0.00e+00	2284.00
IUUC-Atr-002493	Amborella trichopoda	80.97	0.00e+00	1982.00
IUUC-Aly-006020	Arabidopsis lyrata	77.96	0.00e+00	1941.00
IUUC-Ath-007058	Arabidopsis thaliana	77.93	0.00e+00	1947.00
IUUC-Ago-007992	Ashbya gossypii	43.61	0.00e+00	984.00
IUUC-Afl-008644	Aspergillus flavus	47.41	0.00e+00	1120.00
IUUC-Ani-009379	Aspergillus nidulans	54.99	0.00e+00	972.00
IUUC-Ang-009756	Aspergillus niger	47.41	0.00e+00	1131.00
IUUC-Aor-010174	Aspergillus oryzae	47.41	0.00e+00	1122.00
IUUC-Ate-010302	Aspergillus terreus	47.31	0.00e+00	1151.00
IUUC-Bci-013781	Botrytis cinerea	46.31	0.00e+00	1111.00
IUUC-Bdi-014549	Brachypodium distachyon	89.33	0.00e+00	2269.00
IUUC-Bol-015925	Brassica oleracea	76.17	0.00e+00	1904.00
IUUC-Bra-016978	Brassica rapa	77.40	0.00e+00	1932.00
IUUC-Cel-018115	Caenorhabditis elegans	55.53	0.00e+00	940.00
IUUC-Cho-024704	Choloepus hoffmanni	41.09	5.00e-162	564.00
IUUC-Cin-025572	Ciona intestinalis	50.28	0.00e+00	1241.00
IUUC-Csv-025864	Ciona savignyi	56.79	0.00e+00	976.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.70	0.00e+00	979.00
IUUC-Cne-027053	Cryptococcus neoformans	50.81	0.00e+00	1174.00
IUUC-Cme-027222	Cyanidioschyzon merolae	42.81	1.00e-146	513.00
IUUC-Dre-027421	Danio rerio	53.78	0.00e+00	1333.00
IUUC-Dno-029303	Dasypus novemcinctus	54.82	0.00e+00	1362.00
IUUC-Fca-035739	Felis catus	53.62	0.00e+00	1321.00
IUUC-Fox-037738	Fusarium oxysporum	47.45	0.00e+00	1125.00
IUUC-Fso-038153	Fusarium solani	46.96	0.00e+00	1118.00
IUUC-Ggr-039931	Gaeumannomyces graminis	54.26	0.00e+00	961.00
IUUC-Hvu-047316	Hordeum vulgare	93.58	0.00e+00	2217.00
IUUC-Lpe-051316	Leersia perrieri	97.62	0.00e+00	2347.00
IUUC-Lma-053138	Leptosphaeria maculans	55.24	0.00e+00	995.00
IUUC-Laf-053510	Loxodonta africana	54.89	0.00e+00	1360.00
IUUC-Mor-057172	Magnaporthe oryzae	46.39	0.00e+00	1098.00
IUUC-Mpo-057300	Magnaporthe poae	46.45	0.00e+00	1092.00
IUUC-Mla-059019	Melampsora laricipopulina	50.24	0.00e+00	1213.00
IUUC-Mga-059499	Meleagris gallopavo	54.24	0.00e+00	1342.00
IUUC-Mvi-060336	Microbotryum violaceum	50.65	0.00e+00	1207.00
IUUC-Mac-065272	Musa acuminata	73.89	0.00e+00	1843.00
IUUC-Mlu-067392	Myotis lucifugus	54.65	0.00e+00	1337.00
IUUC-Ncr-068892	Neurospora crassa	47.39	0.00e+00	1105.00
IUUC-Oba-075761	Oryza barthii	98.27	0.00e+00	2372.00
IUUC-Obr-076429	Oryza brachyantha	95.32	0.00e+00	2331.00
IUUC-Ogl-077364	Oryza glaberrima	98.85	0.00e+00	2382.00
IUUC-Ogu-078257	Oryza glumaepatula	98.24	0.00e+00	2308.00
IUUC-Oin-079274	Oryza indica	98.85	0.00e+00	2383.00
IUUC-Ome-081668	Oryza meridionalis	92.08	0.00e+00	2009.00
IUUC-Oni-082874	Oryza nivara	99.01	0.00e+00	2383.00
IUUC-Oru-084274	Oryza rufipogon	98.77	0.00e+00	2379.00
IUUC-Osa-085565	Oryza sativa	98.77	0.00e+00	2379.00
IUUC-Olu-087639	Ostreococcus lucimarinus	60.71	0.00e+00	1534.00
IUUC-Pno-094839	Phaeosphaeria nodorum	45.58	0.00e+00	1051.00
IUUC-Ppa-095390	Physcomitrella patens	69.31	0.00e+00	1734.00
IUUC-Pop-100086	Populus trichocarpa	80.33	0.00e+00	2002.00
IUUC-Pca-100413	Procavia capensis	60.61	0.00e+00	693.00
IUUC-Ppe-101392	Prunus persica	80.98	0.00e+00	2038.00
IUUC-Pva-102126	Pteropus vampyrus	52.09	0.00e+00	1273.00
IUUC-Pgr-103376	Puccinia graminis	50.08	0.00e+00	1222.00
IUUC-Ptt-103978	Puccinia triticina	45.11	0.00e+00	983.00
IUUC-Pte-104126	Pyrenophora teres	54.90	0.00e+00	947.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	45.11	0.00e+00	1073.00
IUUC-Sit-109697	Setaria italica	93.93	0.00e+00	2293.00
IUUC-Sly-111759	Solanum lycopersicum	79.92	0.00e+00	2025.00
IUUC-Stu-112564	Solanum tuberosum	80.08	0.00e+00	2024.00
IUUC-Sbi-114388	Sorghum bicolor	94.01	0.00e+00	2293.00
IUUC-Sre-115209	Sporisorium reilianum	55.42	0.00e+00	1001.00
IUUC-Tni-120556	Tetraodon nigroviridis	41.29	0.00e+00	865.00
IUUC-Tca-121545	Theobroma cacao	79.10	0.00e+00	2013.00
IUUC-Tre-121951	Trichoderma reesei	46.33	0.00e+00	1088.00
IUUC-Tvi-122359	Trichoderma virens	46.80	0.00e+00	1110.00
IUUC-Tur-126754	Triticum urartu	92.53	0.00e+00	2245.00
IUUC-Tme-127170	Tuber melanosporum	48.09	0.00e+00	1174.00
IUUC-Tbe-127882	Tupaia belangeri	68.71	1.00e-128	454.00
IUUC-Uma-129337	Ustilago maydis	55.54	0.00e+00	998.00
IUUC-Vda-129828	Verticillium dahliae	47.52	0.00e+00	1113.00
IUUC-Vpa-130537	Vicugna pacos	53.91	0.00e+00	1328.00
IUUC-Xtr-132857	Xenopus tropicalis	52.36	0.00e+00	1265.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence