iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091424

UUCD1 version

UUC-PaT-00625

Ensembl Protein ID

ENSPTRP00000031402.6

UniProt Accession

H2QTB6; H2QTB6_PANTR

Genbank Protein ID

JAA07086.1; JAA21520.1; JAA31146.1; JAA41740.1

Protein Name

Inhibitor of Bruton agammaglobulinemia tyrosine kinase

Genbank Nucleotide ID

AACZ03046066; GABF01000625; GABD01001954; GABE01002999

Gene Name

IBTK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000018375.6	ENSPTRT00000033982.6	ENSPTRP00000031402.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	6.70e-26	90.4	565	641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmelees.............ksklmveikdvqpevfrallkFlYtgkld 66
           Dv+++vg++ f+ahk++La +S++F++lfl++ + s                   +++ v p+ f+ ll+F+Yt++ d
   Q: 565  DVTFQVGNRLFPAHKYILAVHSDFFQKLFLSDGNTSeftdiyqkdedsaG-CHLFVVEKVHPDMFEYLLQFIYTDTCD 641
           9****************************9999988899*****996532.23344445***************9876 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MNSPMPDCTS KCRSLKHALD VLSVVTKGSE NQIKAFLSSH CYNAATIKDV FGRNALHLVS 60
SCGKKGVLDW LIQKGVDLLV KDKESGWTAL HRSIFYGHID CVWSLLKHGV SLYIQDKEGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCTCTAC ATCCCCGTTC CCGATTCCTG TAGTAGCGGC TGTATTGCAG CCGCCTGCCG 60
AACTGACCCG GGTCTGGGGA CTGGCCCCTC TGGCGCCGTT CGGTTTCTCT TATTGCCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000210--BTB/POZ_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR011333--SKP1/BTB/POZ

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50097--BTB
PS50012--RCC1_3

Pfam

PF12796--Ank_2
PF00651--BTB
PF00415--RCC1

SMART

SM00248--ANK
SM00225--BTB

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0016301--F:kinase activity
GO:0030292--F:protein tyrosine kinase inhibitor activity
GO:0051209--P:release of sequestered calcium ion into cytosol

KEGG

ptr:462849

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000696	Aegilops tauschii	31.35	2.00e-40	161.00
IUUC-Aml-001765	Ailuropoda melanoleuca	90.49	0.00e+00	2384.00
IUUC-Atr-003012	Amborella trichopoda	31.46	1.00e-32	135.00
IUUC-Apl-003868	Anas platyrhynchos	72.08	0.00e+00	1946.00
IUUC-Aca-004897	Anolis carolinensis	66.81	0.00e+00	1712.00
IUUC-Aly-005989	Arabidopsis lyrata	30.11	2.00e-36	147.00
IUUC-Ath-007268	Arabidopsis thaliana	29.89	1.00e-35	145.00
IUUC-Ago-007942	Ashbya gossypii	24.48	8.00e-11	63.20
IUUC-Acl-008353	Aspergillus clavatus	26.53	1.00e-31	132.00
IUUC-Afl-008409	Aspergillus flavus	26.28	7.00e-36	146.00
IUUC-Afu-008944	Aspergillus fumigatus	25.10	5.00e-33	137.00
IUUC-Ani-009309	Aspergillus nidulans	25.55	4.00e-31	131.00
IUUC-Ang-009872	Aspergillus niger	28.48	8.00e-38	153.00
IUUC-Aor-010054	Aspergillus oryzae	26.28	5.00e-36	147.00
IUUC-Ate-010319	Aspergillus terreus	21.99	3.00e-12	68.20
IUUC-Ame-010972	Astyanax mexicanus	57.02	0.00e+00	1423.00
IUUC-Bgr-012036	Blumeria graminis	25.89	3.00e-29	124.00
IUUC-Bta-012491	Bos taurus	90.32	0.00e+00	2394.00
IUUC-Bci-013874	Botrytis cinerea	26.00	4.00e-34	140.00
IUUC-Bdi-014094	Brachypodium distachyon	30.52	5.00e-41	163.00
IUUC-Bol-015876	Brassica oleracea	29.97	3.00e-32	134.00
IUUC-Bra-017155	Brassica rapa	29.97	2.00e-34	141.00
IUUC-Cja-019928	Callithrix jacchus	94.61	0.00e+00	2502.00
IUUC-Cfa-021191	Canis familiaris	90.84	0.00e+00	2445.00
IUUC-Cpo-021893	Cavia porcellus	86.10	0.00e+00	1470.00
IUUC-Csa-023410	Chlorocebus sabaeus	97.93	0.00e+00	2627.00
IUUC-Cho-024939	Choloepus hoffmanni	81.86	0.00e+00	1926.00
IUUC-Cin-025713	Ciona intestinalis	33.91	1.00e-140	494.00
IUUC-Cgl-026577	Colletotrichum gloeosporioides	23.38	4.00e-15	77.80
IUUC-Cne-026961	Cryptococcus neoformans	30.90	2.00e-21	98.60
IUUC-Cme-027274	Cyanidioschyzon merolae	30.62	8.00e-12	66.20
IUUC-Dre-027465	Danio rerio	54.80	0.00e+00	1376.00
IUUC-Dno-029885	Dasypus novemcinctus	90.32	0.00e+00	2407.00
IUUC-Dor-030105	Dipodomys ordii	87.03	0.00e+00	924.00
IUUC-Dse-031213	Dothistroma septosporum	26.58	1.00e-37	152.00
IUUC-Dme-031915	Drosophila melanogaster	26.69	1.00e-65	245.00
IUUC-Ete-033002	Echinops telfairi	74.93	0.00e+00	1890.00
IUUC-Eca-034271	Equus caballus	91.50	0.00e+00	2449.00
IUUC-Eeu-034921	Erinaceus europaeus	82.25	0.00e+00	2144.00
IUUC-Fca-036135	Felis catus	88.82	0.00e+00	2415.00
IUUC-Fal-036815	Ficedula albicollis	72.28	0.00e+00	1843.00
IUUC-Fox-037821	Fusarium oxysporum	24.79	3.00e-19	91.70
IUUC-Fso-038316	Fusarium solani	26.36	1.00e-21	99.40
IUUC-Gmo-038841	Gadus morhua	55.46	0.00e+00	1368.00
IUUC-Ggr-040105	Gaeumannomyces graminis	26.87	2.00e-20	95.90
IUUC-Gga-040756	Gallus gallus	72.06	0.00e+00	1875.00
IUUC-Gac-041957	Gasterosteus aculeatus	57.47	0.00e+00	1429.00
IUUC-Gma-043801	Glycine max	30.14	1.00e-40	161.00
IUUC-Ggo-044737	Gorilla gorilla	96.01	0.00e+00	2529.00
IUUC-Hsa-046756	Homo sapiens	99.41	0.00e+00	2640.00
IUUC-Itr-048204	Ictidomys tridecemlineatus	92.17	0.00e+00	2436.00
IUUC-Lch-050082	Latimeria chalumnae	75.14	6.00e-81	292.00
IUUC-Lpe-050709	Leersia perrieri	31.72	7.00e-43	169.00
IUUC-Loc-052669	Lepisosteus oculatus	62.59	0.00e+00	1616.00
IUUC-Lma-053227	Leptosphaeria maculans	27.07	7.00e-38	153.00
IUUC-Laf-053898	Loxodonta africana	90.18	0.00e+00	2370.00
IUUC-Mcc-055614	Macaca mulatta	97.71	0.00e+00	2597.00
IUUC-Meu-056803	Macropus eugenii	54.82	0.00e+00	1134.00
IUUC-Mor-056973	Magnaporthe oryzae	22.49	7.00e-39	156.00
IUUC-Mpo-057627	Magnaporthe poae	21.74	6.00e-29	123.00
IUUC-Mtr-058718	Medicago truncatula	30.32	7.00e-41	162.00
IUUC-Mla-058948	Melampsora laricipopulina	28.71	1.00e-29	126.00
IUUC-Mga-059344	Meleagris gallopavo	71.21	0.00e+00	1837.00
IUUC-Mvi-060265	Microbotryum violaceum	26.49	1.00e-28	122.00
IUUC-Mmr-061025	Microcebus murinus	92.46	0.00e+00	2446.00
IUUC-Mdo-061884	Monodelphis domestica	77.66	0.00e+00	2043.00
IUUC-Mmu-063492	Mus musculus	85.75	0.00e+00	2237.00
IUUC-Mac-065442	Musa acuminata	29.17	1.00e-38	155.00
IUUC-Mpu-065714	Mustela putorius furo	89.66	0.00e+00	2395.00
IUUC-Mlu-068229	Myotis lucifugus	88.41	0.00e+00	2319.00
IUUC-Nfi-068585	Neosartorya fischeri	25.51	2.00e-34	141.00
IUUC-Ncr-068789	Neurospora crassa	28.94	1.00e-18	90.10
IUUC-Nle-070017	Nomascus leucogenys	98.74	0.00e+00	2624.00
IUUC-Opr-070430	Ochotona princeps	75.39	0.00e+00	1937.00
IUUC-Ont-071686	Oreochromis niloticus	58.80	0.00e+00	1484.00
IUUC-Oan-073539	Ornithorhynchus anatinus	75.40	0.00e+00	1844.00
IUUC-Ocu-074076	Oryctolagus cuniculus	90.77	0.00e+00	2392.00
IUUC-Oba-075204	Oryza barthii	31.73	3.00e-43	170.00
IUUC-Obr-076797	Oryza brachyantha	32.75	6.00e-42	166.00
IUUC-Ogl-077619	Oryza glaberrima	32.15	2.00e-44	174.00
IUUC-Ogu-078961	Oryza glumaepatula	31.94	1.00e-43	171.00
IUUC-Oin-079261	Oryza indica	31.94	1.00e-43	172.00
IUUC-Olo-080829	Oryza longistaminata	31.94	7.00e-44	172.00
IUUC-Ome-081599	Oryza meridionalis	31.73	3.00e-43	170.00
IUUC-Oni-082029	Oryza nivara	31.94	4.00e-43	170.00
IUUC-Opu-083657	Oryza punctata	32.29	6.00e-43	169.00
IUUC-Oru-084765	Oryza rufipogon	31.94	1.00e-43	171.00
IUUC-Osa-086136	Oryza sativa	31.94	7.00e-43	169.00
IUUC-Ola-087419	Oryzias latipes	59.90	0.00e+00	1514.00
IUUC-Oga-088885	Otolemur garnettii	88.32	0.00e+00	2329.00
IUUC-Oar-090361	Ovis aries	89.44	0.00e+00	2367.00
IUUC-Pan-092557	Papio anubis	96.61	0.00e+00	2569.00
IUUC-Psi-093980	Pelodiscus sinensis	73.20	0.00e+00	1927.00
IUUC-Pno-094989	Phaeosphaeria nodorum	28.66	4.00e-32	134.00
IUUC-Ppa-095929	Physcomitrella patens	33.53	6.00e-41	162.00
IUUC-Pfo-096296	Poecilia formosa	55.88	0.00e+00	1426.00
IUUC-Pab-097552	Pongo abelii	99.11	0.00e+00	2636.00
IUUC-Pop-099124	Populus trichocarpa	30.09	1.00e-41	165.00
IUUC-Pca-100417	Procavia capensis	84.30	0.00e+00	927.00
IUUC-Ppe-101574	Prunus persica	35.36	4.00e-38	153.00
IUUC-Pva-102906	Pteropus vampyrus	85.74	0.00e+00	2248.00
IUUC-Pgr-103405	Puccinia graminis	28.30	7.00e-32	133.00
IUUC-Ptt-103743	Puccinia triticina	29.41	5.00e-36	147.00
IUUC-Pte-104407	Pyrenophora teres	27.27	2.00e-39	158.00
IUUC-Pyt-104646	Pyrenophora triticirepentis	27.27	2.00e-39	158.00
IUUC-Rno-105118	Rattus norvegicus	83.60	0.00e+00	2172.00
IUUC-Sha-106797	Sarcophilus harrisii	77.02	0.00e+00	1988.00
IUUC-Sja-107740	Schizosaccharomyces japonicus	28.80	4.00e-42	167.00
IUUC-Spo-108090	Schizosaccharomyces pombe	32.87	5.00e-39	157.00
IUUC-Ssl-108513	Sclerotinia sclerotiorum	24.71	1.00e-27	119.00
IUUC-Smo-109576	Selaginella moellendorffii	33.52	1.00e-37	152.00
IUUC-Sit-110676	Setaria italica	31.17	2.00e-42	167.00
IUUC-Sly-111572	Solanum lycopersicum	28.87	1.00e-30	128.00
IUUC-Sar-113437	Sorex araneus	79.91	0.00e+00	2040.00
IUUC-Sbi-114124	Sorghum bicolor	30.99	3.00e-40	160.00
IUUC-Sre-114999	Sporisorium reilianum	28.61	1.00e-33	139.00
IUUC-Ssc-116088	Sus scrofa	90.32	0.00e+00	2308.00
IUUC-Tgu-116854	Taeniopygia guttata	72.29	0.00e+00	1890.00
IUUC-Tru-117552	Takifugu rubripes	56.75	0.00e+00	1425.00
IUUC-Tsy-118821	Tarsius syrichta	86.68	0.00e+00	2023.00
IUUC-Tni-119891	Tetraodon nigroviridis	57.09	0.00e+00	1436.00
IUUC-Tca-121015	Theobroma cacao	29.40	1.00e-38	155.00
IUUC-Tre-122202	Trichoderma reesei	25.91	4.00e-23	104.00
IUUC-Tvi-122439	Trichoderma virens	26.61	1.00e-22	102.00
IUUC-Tae-123606	Triticum aestivum	31.86	2.00e-41	164.00
IUUC-Tur-126077	Triticum urartu	31.82	2.00e-39	157.00
IUUC-Tme-127029	Tuber melanosporum	29.27	2.00e-28	122.00
IUUC-Tbe-127811	Tupaia belangeri	77.91	0.00e+00	1211.00
IUUC-Ttr-128664	Tursiops truncatus	85.71	0.00e+00	2032.00
IUUC-Uma-129427	Ustilago maydis	28.75	3.00e-32	134.00
IUUC-Vda-129791	Verticillium dahliae	26.07	6.00e-22	100.00
IUUC-Vpa-130558	Vicugna pacos	84.04	0.00e+00	2151.00
IUUC-Vvi-131602	Vitis vinifera	34.52	1.00e-37	152.00
IUUC-Xtr-131965	Xenopus tropicalis	62.62	0.00e+00	1559.00
IUUC-Xma-133569	Xiphophorus maculatus	55.97	0.00e+00	1434.00
IUUC-Yli-134409	Yarrowia lipolytica	30.88	2.00e-26	115.00
IUUC-Zma-135450	Zea mays	30.72	3.00e-42	167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence