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Tag Content
iUUCD ID IUUC-Bci-013643
Ensembl Protein ID Bcin09g03560.1
UniProt Accession A6SB28; NACA_BOTFB
Genbank Protein ID EDN30663.1
Protein Name Nascent polypeptide-associated complex subunit alpha; Alpha-NAC
Genbank Nucleotide ID CH476906
Gene Name egd2; BC1G_09983
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
Bcin09g03560 Bcin09g03560.1 Bcin09g03560.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 48.61 9.00e-15 74.70 IUUC-Sce-106371
UBD/Alpha-Helix/UBA 46.20 2.00e-26 113.00 IUUC-Spo-108121
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Botrytis cinerea
Functional Description
(View)

Functional Description



     Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Protein Sequence
(Fasta)
MSNPRIEELP DNEEPTKQQV TAEDEGSDSS DSEAEGEEVA GIPAGSQVAF SRNEKKARKS 60
IAKLGLTRVP GITRVTLRRP KNILFVINQP EVYKSPTSNT YIVFGEAKIE DLNSQAQASA 120
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Protein Fasta Sequence



>IUUC-Bci-013643|UBD,UBA|Botrytis cinerea
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Nucleotide Sequence
(Fasta)
ATGTCGAACC CACGTATTGA AGAACTCCCA GATAACGAGG AGCCAACCAA GCAACAAGTT 60
ACCGCAGAGG ATGAGGGATC CGACAGCTCT GACTCTGAGG CAGAGGGAGA GGAGGTAGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Bci-013643|UBD,UBA|Botrytis cinerea
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0653--Protein transport
KW-0813--Transport

Interpro

IPR016641--EGD2/NACA
IPR002715--Nas_poly-pep-assoc_cplx_dom

PROSITE

PS51151--NAC_AB

Pfam

PF01849--NAC

SMART

SM01407--NAC

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0015031--P:protein transport

KEGG bfu:BC1G_09983
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001167 Aegilops tauschii 57.69 1.00e-16 77.80
IUUC-Aml-002185 Ailuropoda melanoleuca 63.41 3.00e-10 59.70
IUUC-Atr-002586 Amborella trichopoda 41.18 2.00e-10 57.00
IUUC-Apl-003190 Anas platyrhynchos 66.15 1.00e-21 94.00
IUUC-Aca-005265 Anolis carolinensis 73.02 2.00e-24 103.00
IUUC-Aly-006488 Arabidopsis lyrata 57.69 9.00e-16 75.10
IUUC-Ath-007378 Arabidopsis thaliana 57.69 2.00e-15 74.30
IUUC-Ago-007936 Ashbya gossypii 50.00 3.00e-16 75.90
IUUC-Acl-008036 Aspergillus clavatus 63.96 3.00e-32 129.00
IUUC-Afl-008462 Aspergillus flavus 69.30 1.00e-37 147.00
IUUC-Afu-008832 Aspergillus fumigatus 58.18 1.00e-29 121.00
IUUC-Ani-009246 Aspergillus nidulans 65.79 2.00e-33 134.00
IUUC-Ang-009808 Aspergillus niger 62.16 2.00e-31 127.00
IUUC-Aor-009972 Aspergillus oryzae 69.30 1.00e-37 147.00
IUUC-Ame-011674 Astyanax mexicanus 73.02 3.00e-24 103.00
IUUC-Bgr-012162 Blumeria graminis 63.72 2.00e-32 130.00
IUUC-Bta-012508 Bos taurus 73.02 2.00e-24 103.00
IUUC-Bdi-014854 Brachypodium distachyon 57.69 4.00e-16 76.30
IUUC-Bol-015681 Brassica oleracea 55.56 2.00e-16 77.40
IUUC-Bra-017630 Brassica rapa 55.56 2.00e-16 77.40
IUUC-Cel-018111 Caenorhabditis elegans 43.43 4.00e-34 135.00
IUUC-Cja-019846 Callithrix jacchus 65.08 1.00e-21 97.80
IUUC-Cfa-020429 Canis familiaris 73.02 1.00e-24 104.00
IUUC-Cpo-022542 Cavia porcellus 73.02 3.00e-24 103.00
IUUC-Cre-022679 Chlamydomonas reinhardtii 65.08 5.00e-22 95.10
IUUC-Csa-023260 Chlorocebus sabaeus 65.85 3.00e-10 59.70
IUUC-Cho-024869 Choloepus hoffmanni 72.97 2.00e-10 57.00
IUUC-Cin-025166 Ciona intestinalis 64.38 4.00e-24 102.00
IUUC-Csv-026284 Ciona savignyi 73.08 2.00e-19 86.30
IUUC-Cgl-026520 Colletotrichum gloeosporioides 71.05 3.00e-34 136.00
IUUC-Cne-026920 Cryptococcus neoformans 64.38 8.00e-23 98.20
IUUC-Cme-027301 Cyanidioschyzon merolae 57.63 1.00e-18 84.70
IUUC-Dre-028709 Danio rerio 73.02 1.00e-23 103.00
IUUC-Dno-029367 Dasypus novemcinctus 44.44 2.00e-26 114.00
IUUC-Dor-030962 Dipodomys ordii 73.02 3.00e-24 103.00
IUUC-Dme-032061 Drosophila melanogaster 69.84 3.00e-22 96.30
IUUC-Ete-032965 Echinops telfairi 70.27 7.00e-10 55.50
IUUC-Eca-034049 Equus caballus 71.43 1.00e-23 101.00
IUUC-Eeu-034673 Erinaceus europaeus 73.02 2.00e-24 103.00
IUUC-Fca-035429 Felis catus 48.77 4.00e-26 112.00
IUUC-Fal-037006 Ficedula albicollis 73.02 2.00e-24 103.00
IUUC-Fox-037704 Fusarium oxysporum 69.34 9.00e-54 201.00
IUUC-Fso-038247 Fusarium solani 66.98 5.00e-53 198.00
IUUC-Gmo-039002 Gadus morhua 50.62 4.00e-32 129.00
IUUC-Ggr-039888 Gaeumannomyces graminis 69.30 6.00e-35 138.00
IUUC-Gga-040237 Gallus gallus 73.02 2.00e-24 103.00
IUUC-Gac-041800 Gasterosteus aculeatus 73.02 7.00e-24 103.00
IUUC-Gma-043275 Glycine max 63.41 4.00e-09 52.80
IUUC-Ggo-045163 Gorilla gorilla 45.68 3.00e-31 126.00
IUUC-Hsa-045795 Homo sapiens 73.02 3.00e-23 103.00
IUUC-Hvu-047376 Hordeum vulgare 57.69 1.00e-16 77.80
IUUC-Itr-048152 Ictidomys tridecemlineatus 73.02 2.00e-24 103.00
IUUC-Kpa-049166 Komagataella pastoris 54.79 2.00e-18 83.60
IUUC-Lch-050076 Latimeria chalumnae 73.02 1.00e-24 104.00
IUUC-Lpe-051258 Leersia perrieri 44.08 1.00e-25 107.00
IUUC-Loc-052292 Lepisosteus oculatus 73.02 5.00e-24 102.00
IUUC-Lma-053293 Leptosphaeria maculans 64.32 4.00e-48 182.00
IUUC-Laf-054393 Loxodonta africana 41.32 7.00e-28 115.00
IUUC-Mcc-054632 Macaca mulatta 73.02 3.00e-23 103.00
IUUC-Meu-056242 Macropus eugenii 73.02 2.00e-24 103.00
IUUC-Mor-057099 Magnaporthe oryzae 68.42 3.00e-34 136.00
IUUC-Mpo-057543 Magnaporthe poae 62.96 8.00e-27 111.00
IUUC-Mtr-058112 Medicago truncatula 63.49 5.00e-22 95.50
IUUC-Mla-059166 Melampsora laricipopulina 63.41 3.00e-10 56.20
IUUC-Mga-059406 Meleagris gallopavo 73.02 3.00e-24 103.00
IUUC-Mvi-060390 Microbotryum violaceum 35.62 2.00e-20 90.10
IUUC-Mmr-061569 Microcebus murinus 73.02 2.00e-24 103.00
IUUC-Mdo-062077 Monodelphis domestica 73.02 1.00e-23 103.00
IUUC-Mmu-063984 Mus musculus 73.02 2.00e-23 104.00
IUUC-Mac-065175 Musa acuminata 61.11 7.00e-19 85.10
IUUC-Mpu-066751 Mustela putorius furo 65.08 1.00e-21 97.80
IUUC-Mlu-068234 Myotis lucifugus 73.02 2.00e-24 103.00
IUUC-Nfi-068541 Neosartorya fischeri 58.18 1.00e-29 121.00
IUUC-Ncr-068830 Neurospora crassa 69.30 5.00e-36 142.00
IUUC-Nle-069126 Nomascus leucogenys 73.02 3.00e-24 103.00
IUUC-Opr-070742 Ochotona princeps 73.02 3.00e-24 103.00
IUUC-Ont-071828 Oreochromis niloticus 74.19 6.00e-24 102.00
IUUC-Oan-073462 Ornithorhynchus anatinus 69.12 2.00e-23 103.00
IUUC-Ocu-074890 Oryctolagus cuniculus 65.08 1.00e-21 98.20
IUUC-Oba-075995 Oryza barthii 44.74 5.00e-28 115.00
IUUC-Obr-076073 Oryza brachyantha 45.39 2.00e-28 116.00
IUUC-Ogl-077445 Oryza glaberrima 44.74 5.00e-28 115.00
IUUC-Ogu-078606 Oryza glumaepatula 44.74 5.00e-28 115.00
IUUC-Oin-079287 Oryza indica 44.74 5.00e-28 115.00
IUUC-Olo-080686 Oryza longistaminata 42.47 1.00e-13 68.20
IUUC-Ome-081567 Oryza meridionalis 42.11 1.00e-25 107.00
IUUC-Oni-082873 Oryza nivara 44.74 5.00e-28 115.00
IUUC-Opu-083488 Oryza punctata 59.26 4.00e-18 82.80
IUUC-Oru-084592 Oryza rufipogon 44.74 5.00e-28 115.00
IUUC-Osa-086102 Oryza sativa 44.74 6.00e-28 115.00
IUUC-Ola-087531 Oryzias latipes 72.97 2.00e-10 57.40
IUUC-Olu-087895 Ostreococcus lucimarinus 54.00 2.00e-13 66.20
IUUC-Oga-088239 Otolemur garnettii 73.02 2.00e-24 103.00
IUUC-Oar-090371 Ovis aries 65.85 3.00e-10 59.70
IUUC-Ptr-090481 Pan troglodytes 65.08 9.00e-22 98.20
IUUC-Pan-092210 Papio anubis 65.85 5.00e-10 59.70
IUUC-Psi-093588 Pelodiscus sinensis 73.02 2.00e-24 103.00
IUUC-Pma-094702 Petromyzon marinus 73.02 3.00e-24 103.00
IUUC-Pno-094927 Phaeosphaeria nodorum 71.05 2.00e-36 143.00
IUUC-Ppa-095389 Physcomitrella patens 63.93 6.00e-21 92.00
IUUC-Pfo-096744 Poecilia formosa 73.02 3.00e-24 103.00
IUUC-Pab-098044 Pongo abelii 73.02 2.00e-24 103.00
IUUC-Pop-099938 Populus trichocarpa 61.11 3.00e-19 86.30
IUUC-Pca-100355 Procavia capensis 48.15 1.00e-25 110.00
IUUC-Ppe-101786 Prunus persica 50.33 2.00e-28 116.00
IUUC-Pva-102494 Pteropus vampyrus 73.02 2.00e-24 103.00
IUUC-Pgr-103303 Puccinia graminis 40.99 4.00e-23 99.40
IUUC-Ptt-103748 Puccinia triticina 68.18 1.00e-12 64.30
IUUC-Pte-104368 Pyrenophora teres 68.08 6.00e-49 185.00
IUUC-Pyt-104542 Pyrenophora triticirepentis 68.08 2.00e-48 183.00
IUUC-Rno-105387 Rattus norvegicus 73.02 2.00e-23 104.00
IUUC-Sce-106371 Saccharomyces cerevisiae 38.51 3.00e-21 93.20
IUUC-Sha-107189 Sarcophilus harrisii 73.02 2.00e-24 103.00
IUUC-Sja-107942 Schizosaccharomyces japonicus 51.90 4.00e-18 82.40
IUUC-Spo-108121 Schizosaccharomyces pombe 66.67 2.00e-11 60.50
IUUC-Ssl-108595 Sclerotinia sclerotiorum 82.71 5.00e-63 232.00
IUUC-Smo-108783 Selaginella moellendorffii 61.11 3.00e-17 79.70
IUUC-Sit-109728 Setaria italica 57.41 3.00e-17 79.70
IUUC-Sly-110957 Solanum lycopersicum 59.62 3.00e-17 79.70
IUUC-Stu-112873 Solanum tuberosum 57.69 2.00e-16 77.40
IUUC-Sar-113668 Sorex araneus 72.97 3.00e-10 57.00
IUUC-Sbi-114223 Sorghum bicolor 57.69 9.00e-17 78.20
IUUC-Sre-115220 Sporisorium reilianum 46.73 4.00e-21 92.40
IUUC-Ssc-116119 Sus scrofa 73.02 2.00e-24 103.00
IUUC-Tgu-116528 Taeniopygia guttata 73.02 2.00e-24 103.00
IUUC-Tru-117538 Takifugu rubripes 73.02 2.00e-24 103.00
IUUC-Tsy-118855 Tarsius syrichta 72.97 3.00e-10 56.20
IUUC-Tni-120134 Tetraodon nigroviridis 72.97 2.00e-10 57.80
IUUC-Tca-121524 Theobroma cacao 51.63 1.00e-28 117.00
IUUC-Tre-121915 Trichoderma reesei 66.96 2.00e-33 133.00
IUUC-Tvi-122411 Trichoderma virens 66.67 3.00e-30 123.00
IUUC-Tae-123448 Triticum aestivum 57.69 1.00e-16 77.80
IUUC-Tur-126821 Triticum urartu 57.69 2.00e-16 77.00
IUUC-Tme-126875 Tuber melanosporum 62.83 5.00e-31 125.00
IUUC-Tbe-127759 Tupaia belangeri 67.57 7.00e-09 52.00
IUUC-Ttr-129124 Tursiops truncatus 71.05 4.00e-10 59.30
IUUC-Uma-129551 Ustilago maydis 44.95 2.00e-21 94.00
IUUC-Vda-129992 Verticillium dahliae 63.55 2.00e-50 189.00
IUUC-Vpa-130096 Vicugna pacos 71.43 1.00e-21 94.40
IUUC-Vvi-130940 Vitis vinifera 59.62 9.00e-16 75.10
IUUC-Xtr-132454 Xenopus tropicalis 47.01 2.00e-24 104.00
IUUC-Xma-133842 Xiphophorus maculatus 73.02 3.00e-24 103.00
IUUC-Yli-134485 Yarrowia lipolytica 50.00 4.00e-18 82.80
IUUC-Zma-135748 Zea mays 57.41 4.00e-17 79.30
Created Date 25-Jun-2017

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