iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009271

Ensembl Protein ID

CADANIAP00004316

UniProt Accession

Q5ATX2; C8V7I6; Q5ATX2_EMENI

Genbank Protein ID

CBF74224.1; EAA58996.1

Protein Name

Ubiquitin conjugating enzyme (UbcH), putative (AFU_orthologue AFUA_5G04060)

Genbank Nucleotide ID

BN001302; AACD01000145

Gene Name

ANIA_08258; AN8258.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00004316	CADANIAT00004316	CADANIAP00004316

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.70e-52	176.0	8	158

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.ifhPnvyenGkvClsilk..... 87
           Rl +e+k+l+++pp+gi+a+pv+e+d+++we+li Gpe+tpYeggvF +e++fp+dYP++PP++kf+   ++hPnvy+nG+vC+sil+     
   Q: 8    RLFREYKTLSTNPPDGITAGPVSEDDMFHWEALIQGPEGTPYEGGVFAAELKFPKDYPLSPPTMKFVGGgVWHPNVYPNGTVCISILHppgdd 100
           899****************************************************************999*****************888889 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
                  +e+Wsp +sve++l+s++s+laepn esp+n+eaa++++++r+ey++kvre
   Q: 101  pnhyehASERWSPIQSVEKILISVMSMLAEPNDESPANVEAAKMWRERRAEYERKVRE 158
           99999999***********************************************985 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MSSMTQNRLF REYKTLSTNP PDGITAGPVS EDDMFHWEAL IQGPEGTPYE GGVFAAELKF 60
PKDYPLSPPT MKFVGGGVWH PNVYPNGTVC ISILHPPGDD PNHYEHASER WSPIQSVEKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCATCCA TGACGCAGAA TCGCCTTTTC CGCGAATATA AAACACTATC AACAAACCCG 60
CCGGATGGGA TTACCGCGGG GCCTGTCTCT GAAGATGACA TGTTTCACTG GGAAGCCTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0000837--C:Doa10p ubiquitin ligase complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006333--P:chromatin assembly or disassembly
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0031505--P:fungal-type cell wall organization
GO:0010620--P:negative regulation of transcription by transcription factor catabolism
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ani:AN8258.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000411	Aegilops tauschii	44.63	8.00e-38	147.00
IUUC-Aml-002172	Ailuropoda melanoleuca	61.39	3.00e-55	205.00
IUUC-Atr-003150	Amborella trichopoda	59.86	7.00e-40	154.00
IUUC-Apl-003761	Anas platyrhynchos	61.64	6.00e-56	207.00
IUUC-Aca-005062	Anolis carolinensis	60.84	2.00e-56	209.00
IUUC-Aly-005673	Arabidopsis lyrata	60.42	2.00e-44	169.00
IUUC-Ath-007644	Arabidopsis thaliana	60.42	2.00e-44	169.00
IUUC-Ago-007853	Ashbya gossypii	63.86	9.00e-63	230.00
IUUC-Acl-008080	Aspergillus clavatus	94.58	6.00e-93	330.00
IUUC-Afl-008478	Aspergillus flavus	92.17	1.00e-91	326.00
IUUC-Afu-009051	Aspergillus fumigatus	95.18	3.00e-93	331.00
IUUC-Ang-009748	Aspergillus niger	93.98	2.00e-92	328.00
IUUC-Aor-010228	Aspergillus oryzae	91.57	1.00e-91	326.00
IUUC-Ate-010293	Aspergillus terreus	94.58	6.00e-93	330.00
IUUC-Ame-011698	Astyanax mexicanus	64.46	2.00e-61	226.00
IUUC-Bgr-012226	Blumeria graminis	75.76	5.00e-73	264.00
IUUC-Bta-013324	Bos taurus	59.86	8.00e-47	177.00
IUUC-Bci-013676	Botrytis cinerea	80.00	7.00e-78	280.00
IUUC-Bdi-014838	Brachypodium distachyon	56.77	2.00e-46	176.00
IUUC-Bol-016383	Brassica oleracea	61.54	6.00e-50	187.00
IUUC-Bra-017903	Brassica rapa	59.73	1.00e-44	170.00
IUUC-Cel-018676	Caenorhabditis elegans	61.45	1.00e-59	219.00
IUUC-Cja-019767	Callithrix jacchus	60.24	2.00e-57	213.00
IUUC-Cfa-020047	Canis familiaris	61.45	2.00e-58	216.00
IUUC-Cpo-021507	Cavia porcellus	60.84	1.00e-57	213.00
IUUC-Cre-022895	Chlamydomonas reinhardtii	56.52	9.00e-47	177.00
IUUC-Csa-023745	Chlorocebus sabaeus	60.76	4.00e-55	204.00
IUUC-Cin-025310	Ciona intestinalis	63.52	3.00e-59	218.00
IUUC-Csv-025961	Ciona savignyi	62.89	3.00e-58	215.00
IUUC-Cgl-026553	Colletotrichum gloeosporioides	80.61	1.00e-78	283.00
IUUC-Cne-026903	Cryptococcus neoformans	63.86	2.00e-55	206.00
IUUC-Cme-027321	Cyanidioschyzon merolae	58.28	2.00e-48	182.00
IUUC-Dre-027900	Danio rerio	64.46	2.00e-61	226.00
IUUC-Dno-029688	Dasypus novemcinctus	61.69	2.00e-54	202.00
IUUC-Dor-030686	Dipodomys ordii	50.62	6.00e-42	162.00
IUUC-Dse-031253	Dothistroma septosporum	78.31	1.00e-77	280.00
IUUC-Dme-031849	Drosophila melanogaster	64.46	2.00e-60	222.00
IUUC-Ete-033010	Echinops telfairi	60.84	2.00e-56	209.00
IUUC-Eca-033294	Equus caballus	60.76	4.00e-55	205.00
IUUC-Fca-036442	Felis catus	63.04	5.00e-49	184.00
IUUC-Fal-037188	Ficedula albicollis	62.34	2.00e-55	206.00
IUUC-Fox-037762	Fusarium oxysporum	81.93	4.00e-80	288.00
IUUC-Fso-038181	Fusarium solani	80.72	3.00e-79	285.00
IUUC-Gmo-038663	Gadus morhua	62.05	3.00e-60	222.00
IUUC-Ggr-039808	Gaeumannomyces graminis	80.49	9.00e-79	283.00
IUUC-Gga-040355	Gallus gallus	61.45	2.00e-58	216.00
IUUC-Gac-041847	Gasterosteus aculeatus	61.45	3.00e-59	219.00
IUUC-Gma-044131	Glycine max	59.86	5.00e-39	151.00
IUUC-Ggo-045202	Gorilla gorilla	60.84	5.00e-58	214.00
IUUC-Hsa-046369	Homo sapiens	60.84	5.00e-58	214.00
IUUC-Hvu-047065	Hordeum vulgare	57.72	4.00e-45	172.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	62.05	1.00e-58	217.00
IUUC-Kpa-049317	Komagataella pastoris	63.41	1.00e-60	223.00
IUUC-Lch-049596	Latimeria chalumnae	60.24	1.00e-56	209.00
IUUC-Lpe-051124	Leersia perrieri	57.93	3.00e-44	169.00
IUUC-Loc-052277	Lepisosteus oculatus	59.86	8.00e-47	177.00
IUUC-Lma-053126	Leptosphaeria maculans	81.20	1.00e-61	226.00
IUUC-Laf-054560	Loxodonta africana	60.00	5.00e-55	204.00
IUUC-Mcc-055172	Macaca mulatta	60.84	5.00e-58	214.00
IUUC-Meu-056891	Macropus eugenii	61.39	2.00e-55	206.00
IUUC-Mor-057260	Magnaporthe oryzae	81.71	2.00e-80	289.00
IUUC-Mpo-057468	Magnaporthe poae	79.88	3.00e-78	281.00
IUUC-Mtr-058406	Medicago truncatula	60.54	1.00e-45	174.00
IUUC-Mla-059084	Melampsora laricipopulina	61.08	1.00e-55	207.00
IUUC-Mga-059939	Meleagris gallopavo	59.88	1.00e-55	207.00
IUUC-Mvi-060514	Microbotryum violaceum	62.73	2.00e-56	209.00
IUUC-Mmr-061029	Microcebus murinus	57.99	3.00e-52	195.00
IUUC-Mdo-061820	Monodelphis domestica	61.45	1.00e-58	216.00
IUUC-Mmu-063123	Mus musculus	60.84	5.00e-58	214.00
IUUC-Mac-065294	Musa acuminata	57.33	9.00e-44	167.00
IUUC-Mpu-065866	Mustela putorius furo	58.43	3.00e-55	205.00
IUUC-Mlu-067220	Myotis lucifugus	60.76	4.00e-55	204.00
IUUC-Nfi-068395	Neosartorya fischeri	95.18	3.00e-93	331.00
IUUC-Ncr-068623	Neurospora crassa	76.83	4.00e-75	271.00
IUUC-Nle-070007	Nomascus leucogenys	60.84	5.00e-58	214.00
IUUC-Opr-070958	Ochotona princeps	60.14	2.00e-47	179.00
IUUC-Ont-071736	Oreochromis niloticus	62.65	4.00e-60	221.00
IUUC-Oan-073475	Ornithorhynchus anatinus	58.79	3.00e-55	205.00
IUUC-Ocu-074820	Oryctolagus cuniculus	63.40	2.00e-55	206.00
IUUC-Oba-075915	Oryza barthii	58.62	1.00e-49	186.00
IUUC-Obr-076863	Oryza brachyantha	57.24	5.00e-43	164.00
IUUC-Ogl-076981	Oryza glaberrima	58.62	1.00e-49	186.00
IUUC-Ogu-078183	Oryza glumaepatula	58.62	1.00e-49	186.00
IUUC-Oin-079755	Oryza indica	58.62	1.00e-49	186.00
IUUC-Olo-080576	Oryza longistaminata	58.62	1.00e-49	186.00
IUUC-Ome-081190	Oryza meridionalis	55.56	3.00e-47	179.00
IUUC-Oni-083010	Oryza nivara	58.62	1.00e-49	186.00
IUUC-Opu-083784	Oryza punctata	57.93	5.00e-44	168.00
IUUC-Oru-084817	Oryza rufipogon	58.62	1.00e-49	186.00
IUUC-Osa-085291	Oryza sativa	58.62	1.00e-49	186.00
IUUC-Ola-087571	Oryzias latipes	62.05	1.00e-59	220.00
IUUC-Olu-087887	Ostreococcus lucimarinus	53.99	1.00e-49	186.00
IUUC-Oga-088473	Otolemur garnettii	58.71	2.00e-48	182.00
IUUC-Oar-089706	Ovis aries	60.84	4.00e-58	214.00
IUUC-Ptr-090798	Pan troglodytes	60.84	5.00e-58	214.00
IUUC-Pan-091967	Papio anubis	60.84	5.00e-58	214.00
IUUC-Psi-093524	Pelodiscus sinensis	64.90	1.00e-55	206.00
IUUC-Pma-094602	Petromyzon marinus	67.14	1.00e-52	196.00
IUUC-Pno-094979	Phaeosphaeria nodorum	79.52	5.00e-78	281.00
IUUC-Ppa-095611	Physcomitrella patens	60.65	4.00e-53	198.00
IUUC-Pfo-097330	Poecilia formosa	62.65	8.00e-60	220.00
IUUC-Pab-098225	Pongo abelii	60.24	2.00e-57	213.00
IUUC-Pop-099881	Populus trichocarpa	58.44	4.00e-48	182.00
IUUC-Pca-101040	Procavia capensis	61.69	2.00e-54	202.00
IUUC-Ppe-101778	Prunus persica	60.14	6.00e-46	174.00
IUUC-Pva-103074	Pteropus vampyrus	59.86	1.00e-46	177.00
IUUC-Pgr-103674	Puccinia graminis	59.04	4.00e-53	198.00
IUUC-Ptt-103840	Puccinia triticina	57.83	4.00e-52	195.00
IUUC-Pte-104389	Pyrenophora teres	78.92	4.00e-77	278.00
IUUC-Pyt-104703	Pyrenophora triticirepentis	79.52	3.00e-77	278.00
IUUC-Rno-105228	Rattus norvegicus	60.84	5.00e-58	214.00
IUUC-Sce-106233	Saccharomyces cerevisiae	60.24	1.00e-57	213.00
IUUC-Sha-107274	Sarcophilus harrisii	60.84	3.00e-56	209.00
IUUC-Sja-107937	Schizosaccharomyces japonicus	68.90	4.00e-65	238.00
IUUC-Spo-108269	Schizosaccharomyces pombe	68.90	1.00e-64	236.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	80.00	2.00e-78	282.00
IUUC-Smo-109401	Selaginella moellendorffii	58.06	3.00e-37	145.00
IUUC-Sit-110784	Setaria italica	59.03	2.00e-44	169.00
IUUC-Sly-111843	Solanum lycopersicum	58.06	2.00e-45	172.00
IUUC-Stu-112865	Solanum tuberosum	58.28	7.00e-46	174.00
IUUC-Sbi-113787	Sorghum bicolor	54.84	2.00e-45	173.00
IUUC-Sre-114952	Sporisorium reilianum	60.84	1.00e-55	207.00
IUUC-Ssc-115365	Sus scrofa	61.69	1.00e-54	203.00
IUUC-Tgu-116816	Taeniopygia guttata	61.45	2.00e-58	216.00
IUUC-Tru-117873	Takifugu rubripes	57.69	3.00e-48	182.00
IUUC-Tsy-119168	Tarsius syrichta	59.86	2.00e-46	177.00
IUUC-Tni-120278	Tetraodon nigroviridis	61.08	8.00e-57	210.00
IUUC-Tca-121680	Theobroma cacao	62.99	9.00e-39	151.00
IUUC-Tre-122131	Trichoderma reesei	80.00	4.00e-77	278.00
IUUC-Tvi-122669	Trichoderma virens	80.61	3.00e-78	282.00
IUUC-Tae-123772	Triticum aestivum	58.06	1.00e-47	180.00
IUUC-Tur-126873	Triticum urartu	57.82	2.00e-45	174.00
IUUC-Tme-127052	Tuber melanosporum	67.07	3.00e-64	235.00
IUUC-Tbe-127792	Tupaia belangeri	60.84	5.00e-58	214.00
IUUC-Ttr-128609	Tursiops truncatus	59.86	2.00e-46	177.00
IUUC-Uma-129587	Ustilago maydis	60.84	4.00e-56	208.00
IUUC-Vda-129914	Verticillium dahliae	80.61	4.00e-79	284.00
IUUC-Vpa-130208	Vicugna pacos	60.14	2.00e-47	180.00
IUUC-Vvi-131387	Vitis vinifera	59.18	1.00e-44	170.00
IUUC-Xtr-132450	Xenopus tropicalis	62.05	1.00e-59	219.00
IUUC-Xma-133016	Xiphophorus maculatus	62.65	9.00e-60	220.00
IUUC-Yli-134379	Yarrowia lipolytica	65.85	1.00e-63	233.00
IUUC-Zma-135764	Zea mays	56.00	3.00e-44	169.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence