iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090117

Ensembl Protein ID

ENSOARP00000005635.1

UniProt Accession

W5P5D2; W5P5D2_SHEEP

Genbank Protein ID

ENSOARP00000005635

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01028738

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000005231.1	ENSOART00000005723.1	ENSOARP00000005635.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-26	89.9	153	191
UBD/Beta-Prp	6.50e-50	170.2	496	752

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvl 35
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ l
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDIL 191
           89**********888*****9989*********988765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 496  VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 584
           67899*******************************************99887899**************9997888899********* PP
   S: 98   lslsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtl 175
           ++++f  ++   ++s ++d+ i     ++ q  ++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  
   Q: 585  TAIKFAGNRdIQMISCGADKSIYF---RSAQRASDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGS 670
           *******885789*******9976...444444444444332111222233446777778****************9888888888888 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dl 251
           +g +++s  ++ +d++g++l++   d+++ + d+ +gecv ++ gh++ v+ ++f+ +  +l+++s D  ++iW       ++
   Q: 671  QG-DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWhlgpeitNC 752
           88.999999999**************************************************************554444433 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAALGSGGYA RNDTVEKLPS VMAGVPARRA QSSPPPAPPL CLRRRTRLPA APEDTVQNRV 60
SLEKVLGITA QNSSGLTCDP STGHVAYLAG CVVVILNPKE NKQQHILNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCT TGGGGTCCGG AGGCTACGCG CGGAATGATA CAGTTGAGAA GCTGCCATCA 60
GTCATGGCGG GAGTTCCGGC GCGGAGGGCC CAGTCTTCTC CGCCCCCGGC TCCACCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	80.53	0.00e+00	2279.00
IUUC-Aca-004935	Anolis carolinensis	65.90	0.00e+00	932.00
IUUC-Afu-008757	Aspergillus fumigatus	22.35	9.00e-30	125.00
IUUC-Ang-009797	Aspergillus niger	21.45	5.00e-21	96.70
IUUC-Ate-010425	Aspergillus terreus	23.05	2.00e-26	114.00
IUUC-Bta-013336	Bos taurus	93.36	0.00e+00	2614.00
IUUC-Cja-019094	Callithrix jacchus	75.57	0.00e+00	2076.00
IUUC-Cfa-020529	Canis familiaris	79.12	0.00e+00	2266.00
IUUC-Cpo-021970	Cavia porcellus	83.55	0.00e+00	1570.00
IUUC-Csa-024161	Chlorocebus sabaeus	75.03	0.00e+00	2061.00
IUUC-Cho-024310	Choloepus hoffmanni	80.89	0.00e+00	1070.00
IUUC-Cin-025412	Ciona intestinalis	53.48	5.00e-59	220.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.83	1.00e-25	112.00
IUUC-Dno-029933	Dasypus novemcinctus	74.11	0.00e+00	2014.00
IUUC-Dor-031147	Dipodomys ordii	73.51	0.00e+00	1951.00
IUUC-Dse-031501	Dothistroma septosporum	27.11	2.00e-22	102.00
IUUC-Eca-033675	Equus caballus	80.46	0.00e+00	2217.00
IUUC-Fca-035826	Felis catus	80.13	0.00e+00	2318.00
IUUC-Ggo-045152	Gorilla gorilla	76.65	0.00e+00	2068.00
IUUC-Hsa-045891	Homo sapiens	76.91	0.00e+00	2085.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	89.72	0.00e+00	1461.00
IUUC-Laf-053992	Loxodonta africana	76.09	0.00e+00	2085.00
IUUC-Mcc-054994	Macaca mulatta	76.13	0.00e+00	2045.00
IUUC-Meu-056815	Macropus eugenii	77.30	0.00e+00	1318.00
IUUC-Mmr-060693	Microcebus murinus	75.97	0.00e+00	2057.00
IUUC-Mdo-063007	Monodelphis domestica	60.76	0.00e+00	1643.00
IUUC-Mmu-064067	Mus musculus	72.66	0.00e+00	1989.00
IUUC-Mpu-066532	Mustela putorius furo	80.37	0.00e+00	2299.00
IUUC-Mlu-066982	Myotis lucifugus	80.01	0.00e+00	2164.00
IUUC-Nle-070042	Nomascus leucogenys	83.00	0.00e+00	1790.00
IUUC-Opr-070397	Ochotona princeps	74.14	0.00e+00	2067.00
IUUC-Ocu-074274	Oryctolagus cuniculus	76.44	0.00e+00	2066.00
IUUC-Oga-088577	Otolemur garnettii	76.81	0.00e+00	2137.00
IUUC-Ptr-090553	Pan troglodytes	76.91	0.00e+00	2101.00
IUUC-Pan-092559	Papio anubis	66.78	0.00e+00	974.00
IUUC-Psi-093710	Pelodiscus sinensis	62.32	0.00e+00	1330.00
IUUC-Pab-098510	Pongo abelii	76.01	0.00e+00	2022.00
IUUC-Pca-100323	Procavia capensis	68.62	0.00e+00	1234.00
IUUC-Pva-102895	Pteropus vampyrus	79.74	0.00e+00	2232.00
IUUC-Pte-104373	Pyrenophora teres	25.58	2.00e-28	121.00
IUUC-Pyt-104804	Pyrenophora triticirepentis	25.72	2.00e-28	122.00
IUUC-Rno-105598	Rattus norvegicus	72.81	0.00e+00	2013.00
IUUC-Sha-107013	Sarcophilus harrisii	63.65	0.00e+00	1681.00
IUUC-Sar-113261	Sorex araneus	72.27	0.00e+00	2010.00
IUUC-Ssc-115317	Sus scrofa	82.28	0.00e+00	2246.00
IUUC-Tsy-118799	Tarsius syrichta	83.26	0.00e+00	752.00
IUUC-Tre-122008	Trichoderma reesei	23.65	3.00e-30	127.00
IUUC-Tvi-122281	Trichoderma virens	23.01	2.00e-29	124.00
IUUC-Tbe-127555	Tupaia belangeri	88.36	0.00e+00	926.00
IUUC-Ttr-128722	Tursiops truncatus	80.85	0.00e+00	2268.00
IUUC-Vda-129957	Verticillium dahliae	23.57	1.00e-30	129.00
IUUC-Vpa-130392	Vicugna pacos	62.33	4.00e-173	601.00
IUUC-Xtr-131789	Xenopus tropicalis	56.58	0.00e+00	927.00
IUUC-Yli-134437	Yarrowia lipolytica	26.64	2.00e-16	81.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence