iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010718.1	ENSSHAT00000012622.1	ENSSHAP00000012519.1
ENSSHAG00000010718.1	ENSSHAT00000012623.1	ENSSHAP00000012520.1
ENSSHAG00000010718.1	ENSSHAT00000012624.1	ENSSHAP00000012521.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-29	99.0	95	133
UBD/Beta-Prp	2.00e-55	188.3	433	686

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvl 35
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ +
   Q: 95   GHKYGVACVAFsPNmKHIVSMGyqHDMVVNVWDWKKDSV 133
           89**********888*****9989*********998766 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkgh 93
           +ks ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h
   Q: 433  MKSGVRVMQVSPDGQHLASGDRSGNLRIHELRFMDELIKVEAHDAEVLCLEYSKPETgvtLLASASRDRLIHVLNVDkNYNLEQTLDDH 521
           7888999*********************************************99887899****************97888999***** PP
   S: 94   edsvlslsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkl 171
           ++s+++++f  ++   ++s ++d+ i     ++ q++++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+
   Q: 522  SSSITAIKFAGNRdIQMISCGADKSIY---FRSAQKVSDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKC 607
           ***********885789*******985...4677777777777443222223334456778888****************988888888 PP
   S: 172  lrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
            +  +g +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ v+ ++f+ +  +l+++s D  ++iW l
   Q: 608  YKGSQG-DDGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWQL 686
           888898.999999999**************************************************************43 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

QVTLEKVLGI TAQNSSGLTC DPNTGHIAYL AGCVVVILDP KKSKQQHIFN TARKALSALS 60
FSPDGRYIVT GENGHRPAVR IWDVEEKSQV AEMLGHKYGV ACVAFSPNMK HIVSMGYQHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTAACCC TGGAGAAAGT ACTGGGCATT ACAGCCCAAA ACAGCAGCGG CTTAACATGT 60
GATCCGAACA CAGGCCACAT CGCCTACTTG GCTGGGTGAG TAGTGTGGCT TCTGAGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	66.69	0.00e+00	1820.00
IUUC-Atr-003165	Amborella trichopoda	34.53	6.00e-123	435.00
IUUC-Aca-004935	Anolis carolinensis	72.35	0.00e+00	1030.00
IUUC-Ath-007624	Arabidopsis thaliana	30.47	7.00e-90	325.00
IUUC-Acl-008257	Aspergillus clavatus	22.06	1.00e-26	115.00
IUUC-Afl-008426	Aspergillus flavus	22.63	1.00e-28	122.00
IUUC-Afu-008757	Aspergillus fumigatus	22.68	6.00e-19	89.70
IUUC-Bta-013336	Bos taurus	65.76	0.00e+00	1786.00
IUUC-Cja-019094	Callithrix jacchus	65.70	0.00e+00	1777.00
IUUC-Cfa-020529	Canis familiaris	67.44	0.00e+00	1842.00
IUUC-Cpo-021970	Cavia porcellus	79.12	0.00e+00	1452.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	27.03	1.00e-12	68.60
IUUC-Csa-024161	Chlorocebus sabaeus	66.14	0.00e+00	1735.00
IUUC-Cho-024310	Choloepus hoffmanni	77.10	0.00e+00	1046.00
IUUC-Cin-025412	Ciona intestinalis	56.55	1.00e-57	215.00
IUUC-Csv-026079	Ciona savignyi	42.74	4.00e-83	301.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	24.21	3.00e-27	117.00
IUUC-Dre-028678	Danio rerio	56.78	0.00e+00	1008.00
IUUC-Dno-029933	Dasypus novemcinctus	62.57	0.00e+00	1672.00
IUUC-Dor-031147	Dipodomys ordii	63.77	0.00e+00	1672.00
IUUC-Dse-031501	Dothistroma septosporum	26.96	1.00e-24	108.00
IUUC-Eca-033675	Equus caballus	77.45	0.00e+00	1647.00
IUUC-Fca-035826	Felis catus	66.18	0.00e+00	1842.00
IUUC-Fso-038440	Fusarium solani	23.25	7.00e-34	139.00
IUUC-Gma-043644	Glycine max	31.18	2.00e-99	357.00
IUUC-Ggo-045152	Gorilla gorilla	67.38	0.00e+00	1769.00
IUUC-Hsa-045891	Homo sapiens	67.22	0.00e+00	1743.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	87.64	0.00e+00	1424.00
IUUC-Lch-049669	Latimeria chalumnae	60.14	0.00e+00	1046.00
IUUC-Loc-052488	Lepisosteus oculatus	59.52	0.00e+00	1017.00
IUUC-Lma-053327	Leptosphaeria maculans	24.28	3.00e-35	144.00
IUUC-Laf-053992	Loxodonta africana	64.26	0.00e+00	1787.00
IUUC-Mcc-054994	Macaca mulatta	66.58	0.00e+00	1754.00
IUUC-Meu-056815	Macropus eugenii	91.33	0.00e+00	1571.00
IUUC-Mtr-058383	Medicago truncatula	30.94	7.00e-50	191.00
IUUC-Mmr-060693	Microcebus murinus	65.47	0.00e+00	1778.00
IUUC-Mdo-063007	Monodelphis domestica	80.68	0.00e+00	2215.00
IUUC-Mmu-064067	Mus musculus	64.07	0.00e+00	1729.00
IUUC-Mpu-066532	Mustela putorius furo	67.52	0.00e+00	1879.00
IUUC-Mlu-066982	Myotis lucifugus	63.48	0.00e+00	1720.00
IUUC-Nfi-068613	Neosartorya fischeri	22.16	8.00e-32	132.00
IUUC-Nle-070042	Nomascus leucogenys	74.96	0.00e+00	1615.00
IUUC-Opr-070397	Ochotona princeps	65.10	0.00e+00	1768.00
IUUC-Oan-073119	Ornithorhynchus anatinus	68.32	0.00e+00	892.00
IUUC-Ocu-074274	Oryctolagus cuniculus	64.04	0.00e+00	1724.00
IUUC-Oga-088577	Otolemur garnettii	65.62	0.00e+00	1796.00
IUUC-Oar-090117	Ovis aries	63.78	0.00e+00	1698.00
IUUC-Ptr-090553	Pan troglodytes	67.31	0.00e+00	1761.00
IUUC-Psi-093710	Pelodiscus sinensis	66.48	0.00e+00	1455.00
IUUC-Pab-098510	Pongo abelii	71.86	0.00e+00	1707.00
IUUC-Pop-099155	Populus trichocarpa	31.73	3.00e-98	353.00
IUUC-Pca-100323	Procavia capensis	64.41	0.00e+00	1135.00
IUUC-Pva-102895	Pteropus vampyrus	66.47	0.00e+00	1821.00
IUUC-Rno-105598	Rattus norvegicus	63.54	0.00e+00	1764.00
IUUC-Smo-109134	Selaginella moellendorffii	36.13	2.00e-131	464.00
IUUC-Sly-110969	Solanum lycopersicum	29.43	5.00e-89	322.00
IUUC-Sar-113261	Sorex araneus	64.42	0.00e+00	1749.00
IUUC-Ssc-115317	Sus scrofa	63.48	0.00e+00	1722.00
IUUC-Tsy-118799	Tarsius syrichta	83.37	0.00e+00	798.00
IUUC-Tni-120316	Tetraodon nigroviridis	55.33	0.00e+00	776.00
IUUC-Tca-121475	Theobroma cacao	30.58	6.00e-94	339.00
IUUC-Tre-122008	Trichoderma reesei	23.63	1.00e-32	135.00
IUUC-Tvi-122281	Trichoderma virens	24.30	1.00e-32	134.00
IUUC-Tme-127128	Tuber melanosporum	24.82	2.00e-31	130.00
IUUC-Tbe-127555	Tupaia belangeri	86.91	0.00e+00	909.00
IUUC-Ttr-128722	Tursiops truncatus	64.19	0.00e+00	1737.00
IUUC-Vda-129957	Verticillium dahliae	24.82	2.00e-32	134.00
IUUC-Vpa-130392	Vicugna pacos	88.75	1.00e-78	287.00
IUUC-Xtr-131789	Xenopus tropicalis	60.76	0.00e+00	1004.00
IUUC-Yli-134437	Yarrowia lipolytica	25.08	3.00e-18	87.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence