iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054169

UUCD1 version

UUC-LoA-01107

Ensembl Protein ID

ENSLAFP00000013716.4

UniProt Accession

G3TGT7; G3TGT7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016317.4	ENSLAFT00000016334.4	ENSLAFP00000013716.4
ENSLAFG00000016317.4	ENSLAFT00000036493.1	ENSLAFP00000029119.1
ENSLAFG00000016317.4	ENSLAFT00000035758.1	ENSLAFP00000026792.1
ENSLAFG00000016317.4	ENSLAFT00000031251.1	ENSLAFP00000022153.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-70	238.3	1881	2226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1881 VGLTNLGATCYLASTIQQLYMIPEARQAVFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1960
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1961 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 2019
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2020 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2101
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                +  +++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 2102 MTPYTEDflmgksdrkegfkdasDHAEDAESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 2188
           *******99999999999988886666666***************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2189 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2226
           7779********************************96 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

SVSDIEGGDG LQLRKEHTLK IFAYINSWTQ RQCLCCFKEY KHLEIFNQVV CALINLVIAQ 60
VQVLRDQLCK HCTPINIDST WQDENNQAEE PLNVERECSE ESTERQKSIE KKSDSTRICN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGTATCAG ATATAGAAGG TGGTGATGGA CTGCAGCTCA GAAAGGAGCA TACTCTGAAA 60
ATATTTGCTT ATATCAATTC CTGGACGCAG AGGTACGCAT CTTTAAGTAT TTTGAAGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	97.03	0.00e+00	6751.00
IUUC-Apl-003284	Anas platyrhynchos	93.95	0.00e+00	6248.00
IUUC-Aca-004415	Anolis carolinensis	92.39	0.00e+00	6409.00
IUUC-Acl-008140	Aspergillus clavatus	28.62	3.00e-64	241.00
IUUC-Afl-008381	Aspergillus flavus	28.31	4.00e-64	241.00
IUUC-Afu-008857	Aspergillus fumigatus	26.86	6.00e-64	240.00
IUUC-Ani-009257	Aspergillus nidulans	28.68	1.00e-55	213.00
IUUC-Ang-009759	Aspergillus niger	27.72	6.00e-64	240.00
IUUC-Aor-009931	Aspergillus oryzae	28.31	3.00e-64	241.00
IUUC-Ate-010246	Aspergillus terreus	26.25	3.00e-53	204.00
IUUC-Ame-011219	Astyanax mexicanus	64.72	0.00e+00	2478.00
IUUC-Bgr-012195	Blumeria graminis	26.90	1.00e-64	243.00
IUUC-Bta-012989	Bos taurus	96.78	0.00e+00	6709.00
IUUC-Bci-013798	Botrytis cinerea	32.93	2.00e-58	222.00
IUUC-Cja-018974	Callithrix jacchus	94.10	0.00e+00	796.00
IUUC-Cfa-021214	Canis familiaris	97.08	0.00e+00	6764.00
IUUC-Cpo-021912	Cavia porcellus	96.44	0.00e+00	4683.00
IUUC-Csa-023658	Chlorocebus sabaeus	96.66	0.00e+00	6719.00
IUUC-Cho-024971	Choloepus hoffmanni	83.04	0.00e+00	3175.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	28.15	3.00e-64	241.00
IUUC-Dre-027428	Danio rerio	85.24	0.00e+00	4638.00
IUUC-Dno-029690	Dasypus novemcinctus	96.19	0.00e+00	6566.00
IUUC-Dor-030817	Dipodomys ordii	87.52	0.00e+00	2118.00
IUUC-Dse-031423	Dothistroma septosporum	25.05	3.00e-35	145.00
IUUC-Dme-032102	Drosophila melanogaster	54.27	0.00e+00	852.00
IUUC-Ete-032552	Echinops telfairi	93.18	0.00e+00	2973.00
IUUC-Eca-033457	Equus caballus	97.05	0.00e+00	6468.00
IUUC-Eeu-035118	Erinaceus europaeus	92.96	0.00e+00	3033.00
IUUC-Fca-036213	Felis catus	95.33	0.00e+00	5020.00
IUUC-Fal-037643	Ficedula albicollis	91.86	0.00e+00	6361.00
IUUC-Fox-037971	Fusarium oxysporum	27.59	2.00e-63	238.00
IUUC-Fso-038108	Fusarium solani	27.10	1.00e-59	226.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.39	4.00e-62	234.00
IUUC-Gga-040511	Gallus gallus	91.47	0.00e+00	6388.00
IUUC-Gac-042024	Gasterosteus aculeatus	87.79	0.00e+00	5006.00
IUUC-Ggo-044924	Gorilla gorilla	92.91	0.00e+00	6182.00
IUUC-Hsa-046913	Homo sapiens	96.74	0.00e+00	6750.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	96.50	0.00e+00	6747.00
IUUC-Lch-049675	Latimeria chalumnae	85.72	0.00e+00	4860.00
IUUC-Loc-052832	Lepisosteus oculatus	86.36	0.00e+00	5916.00
IUUC-Lma-053130	Leptosphaeria maculans	27.52	3.00e-60	228.00
IUUC-Mcc-055847	Macaca mulatta	95.75	0.00e+00	6626.00
IUUC-Meu-056327	Macropus eugenii	84.95	0.00e+00	1556.00
IUUC-Mor-057152	Magnaporthe oryzae	35.41	1.00e-61	233.00
IUUC-Mpo-057310	Magnaporthe poae	26.58	4.00e-60	228.00
IUUC-Mmr-060780	Microcebus murinus	96.86	0.00e+00	6742.00
IUUC-Mdo-062308	Monodelphis domestica	91.87	0.00e+00	6120.00
IUUC-Mmu-063457	Mus musculus	94.93	0.00e+00	6633.00
IUUC-Mpu-066917	Mustela putorius furo	94.80	0.00e+00	6551.00
IUUC-Mlu-067696	Myotis lucifugus	96.57	0.00e+00	6706.00
IUUC-Nfi-068259	Neosartorya fischeri	27.21	3.00e-64	241.00
IUUC-Ncr-068911	Neurospora crassa	25.71	2.00e-59	225.00
IUUC-Nle-069586	Nomascus leucogenys	96.58	0.00e+00	6765.00
IUUC-Opr-070447	Ochotona princeps	92.68	0.00e+00	2854.00
IUUC-Ont-072396	Oreochromis niloticus	82.15	0.00e+00	5470.00
IUUC-Oan-073147	Ornithorhynchus anatinus	94.08	0.00e+00	6559.00
IUUC-Ocu-074324	Oryctolagus cuniculus	96.55	0.00e+00	6719.00
IUUC-Ola-086312	Oryzias latipes	81.63	0.00e+00	5262.00
IUUC-Oga-088878	Otolemur garnettii	97.03	0.00e+00	6767.00
IUUC-Oar-089919	Ovis aries	96.81	0.00e+00	6709.00
IUUC-Ptr-090713	Pan troglodytes	96.98	0.00e+00	6215.00
IUUC-Pan-091957	Papio anubis	97.49	0.00e+00	5068.00
IUUC-Psi-093240	Pelodiscus sinensis	92.90	0.00e+00	6466.00
IUUC-Pma-094469	Petromyzon marinus	73.72	0.00e+00	4095.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.76	4.00e-57	218.00
IUUC-Pfo-097159	Poecilia formosa	81.56	0.00e+00	5487.00
IUUC-Pab-098003	Pongo abelii	96.13	0.00e+00	6390.00
IUUC-Pca-100799	Procavia capensis	91.45	0.00e+00	1953.00
IUUC-Pva-103226	Pteropus vampyrus	91.76	0.00e+00	6297.00
IUUC-Pte-104235	Pyrenophora teres	26.45	2.00e-58	222.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	26.96	9.00e-60	226.00
IUUC-Rno-105389	Rattus norvegicus	95.30	0.00e+00	5480.00
IUUC-Sha-106979	Sarcophilus harrisii	93.96	0.00e+00	6521.00
IUUC-Sar-113444	Sorex araneus	89.70	0.00e+00	5874.00
IUUC-Ssc-115815	Sus scrofa	96.37	0.00e+00	5603.00
IUUC-Tgu-117470	Taeniopygia guttata	93.32	0.00e+00	6180.00
IUUC-Tru-118543	Takifugu rubripes	81.87	0.00e+00	5343.00
IUUC-Tsy-119081	Tarsius syrichta	88.25	0.00e+00	4839.00
IUUC-Tni-120294	Tetraodon nigroviridis	80.48	3.00e-161	561.00
IUUC-Tre-122057	Trichoderma reesei	31.43	2.00e-62	236.00
IUUC-Tvi-122570	Trichoderma virens	35.89	9.00e-60	226.00
IUUC-Tme-127154	Tuber melanosporum	27.53	2.00e-59	224.00
IUUC-Tbe-127801	Tupaia belangeri	85.69	0.00e+00	3278.00
IUUC-Ttr-129262	Tursiops truncatus	92.56	0.00e+00	6369.00
IUUC-Vda-129686	Verticillium dahliae	28.06	7.00e-62	233.00
IUUC-Vpa-130484	Vicugna pacos	94.97	0.00e+00	5229.00
IUUC-Xtr-131769	Xenopus tropicalis	85.71	0.00e+00	6029.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence