iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068259

Ensembl Protein ID

CADNFIAP00008361

UniProt Accession

A1DGE8; A1DGE8_NEOFI

Genbank Protein ID

EAW18455.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

DS027696

Gene Name

NFIA_084070

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00008528	CADNFIAT00008528	CADNFIAP00008361

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-70	237.7	1617	1944

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee.fsgyeqqD 91
           GlkNl NtCY+NS+L +L++  ++r+++l+     l+ ++ ++ +++ll + +klf+ ++++  ++v+p+ l++ ++++ +e ++ + q D
   Q: 1617 GLKNLSNTCYLNSLLTQLFMNVQFRDFMLQ-----LHLSD-PDASQRLLAETKKLFAYMQETWLRNVDPQGLVDNIRTYDNEpIDVTIQMD 1701
           9*****************************.....33333.578899*******************************98888******** PP
   S: 92   aqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeet 182
           + Ef + l+d+ e ++                          + ++ k+     ++gql +qik +ec ++s+r epf  ++++++g+   
   Q: 1702 VDEFYNLLFDRWEAQI--------------------------TGTEDKKKFRSFYGGQLVQQIKSKECPHISERLEPFSAIQCEIKGRA-- 1764
           ****************..........................677788888999***********************************.. PP
   S: 183  kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts...pee 270
              sl+++L+++++ e ++g+nky+c++c ++++a+k+  lk++P+ Li+hLkRf f+  +++r+kin+++ fp+++d+spf ++   +++
   Q: 1765 ---SLEESLQAYVEGEIMQGDNKYSCTSCGRHVDAVKRACLKEVPDNLIFHLKRFDFDMITMMRSKINDEFRFPEHIDMSPFKVEylsDQN 1852
           ...9****************************************************************************77766444333 PP
   S: 271  kqkekkkYeLiavvvHsGslssGHYvayvkn.....ekgkWllfdDskVtevkeeevleetg....................staYvlfYk 336
           ++ +++ ++L++v+vHsG+++sGHY++y+++      +g+W++f+Ds V+  + +++  ++                     ++aY+lfY+
   Q: 1853 SDVQEDVFKLVGVLVHSGTAESGHYYSYIRErpnagGRGSWVEFNDSDVSRFDPSKIADQCFggyndsvhpatvnqvrfnkvWNAYMLFYQ 1943
           44459**************************765555666*******************8779***************************9 PP
   S: 337  r 337
           r
   Q: 1944 R 1944
           8 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MAAAPLDSSS TPPDATQSTD STRPHGDSME DLDPQSTRKR PRLDSGSGAV ESLSIDEAAI 60
SRMSKSTSAA PATPGTTDHD VPASTAPASR VTINVKSPTS DTMATESLDT TAEHPGAGPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGCTG CCCCGCTAGA TAGCTCTAGC ACCCCGCCTG ACGCTACTCA ATCCACCGAT 60
TCGACGCGTC CACACGGCGA TTCCATGGAA GATCTCGATC CCCAATCTAC CCGGAAACGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR021905--DUF3517
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF12030--DUF3517
PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

nfi:NFIA_084070

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	27.38	6.00e-64	239.00
IUUC-Apl-003284	Anas platyrhynchos	27.72	2.00e-64	241.00
IUUC-Aca-004415	Anolis carolinensis	27.08	9.00e-64	239.00
IUUC-Acl-008140	Aspergillus clavatus	74.51	0.00e+00	3755.00
IUUC-Afl-008381	Aspergillus flavus	65.78	0.00e+00	3319.00
IUUC-Afu-008857	Aspergillus fumigatus	95.67	0.00e+00	4826.00
IUUC-Ani-009257	Aspergillus nidulans	57.33	0.00e+00	2842.00
IUUC-Ang-009759	Aspergillus niger	62.00	0.00e+00	3132.00
IUUC-Aor-009931	Aspergillus oryzae	67.13	0.00e+00	3067.00
IUUC-Ate-010246	Aspergillus terreus	61.56	0.00e+00	3088.00
IUUC-Ame-011886	Astyanax mexicanus	32.61	1.00e-55	210.00
IUUC-Bgr-012195	Blumeria graminis	36.19	0.00e+00	664.00
IUUC-Bta-012989	Bos taurus	27.70	6.00e-65	242.00
IUUC-Bci-013798	Botrytis cinerea	31.44	0.00e+00	1019.00
IUUC-Cja-018955	Callithrix jacchus	30.28	2.00e-56	214.00
IUUC-Cfa-021214	Canis familiaris	27.70	1.00e-64	241.00
IUUC-Cpo-021912	Cavia porcellus	27.21	2.00e-64	240.00
IUUC-Csa-023658	Chlorocebus sabaeus	27.05	3.00e-64	240.00
IUUC-Cho-025074	Choloepus hoffmanni	31.27	8.00e-48	185.00
IUUC-Cin-025147	Ciona intestinalis	39.21	8.00e-42	161.00
IUUC-Csv-025956	Ciona savignyi	30.67	7.00e-58	218.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	31.68	0.00e+00	897.00
IUUC-Dre-027428	Danio rerio	26.18	7.00e-62	232.00
IUUC-Dno-029690	Dasypus novemcinctus	27.05	8.00e-64	239.00
IUUC-Dor-030817	Dipodomys ordii	34.13	1.00e-64	241.00
IUUC-Dse-031423	Dothistroma septosporum	25.30	1.00e-82	300.00
IUUC-Dme-032102	Drosophila melanogaster	33.07	1.00e-55	212.00
IUUC-Ete-032287	Echinops telfairi	28.06	4.00e-53	202.00
IUUC-Eca-033457	Equus caballus	27.70	4.00e-64	240.00
IUUC-Eeu-035178	Erinaceus europaeus	30.43	1.00e-45	178.00
IUUC-Fca-036213	Felis catus	27.70	1.00e-64	241.00
IUUC-Fal-037643	Ficedula albicollis	27.72	4.00e-64	240.00
IUUC-Fox-037971	Fusarium oxysporum	39.41	9.00e-158	550.00
IUUC-Fso-038108	Fusarium solani	29.29	0.00e+00	888.00
IUUC-Gmo-038587	Gadus morhua	32.51	2.00e-55	209.00
IUUC-Ggr-040075	Gaeumannomyces graminis	29.53	0.00e+00	867.00
IUUC-Gga-040511	Gallus gallus	27.88	3.00e-65	243.00
IUUC-Gac-042024	Gasterosteus aculeatus	26.83	2.00e-61	231.00
IUUC-Ggo-044924	Gorilla gorilla	27.21	6.00e-65	243.00
IUUC-Hsa-046913	Homo sapiens	27.21	1.00e-64	241.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	27.21	8.00e-65	242.00
IUUC-Lch-049675	Latimeria chalumnae	33.73	3.00e-57	216.00
IUUC-Loc-052832	Lepisosteus oculatus	27.29	1.00e-62	234.00
IUUC-Lma-053130	Leptosphaeria maculans	30.24	0.00e+00	845.00
IUUC-Laf-054169	Loxodonta africana	27.21	1.00e-64	241.00
IUUC-Mcc-055217	Macaca mulatta	30.28	2.00e-56	214.00
IUUC-Meu-056659	Macropus eugenii	28.02	3.00e-41	163.00
IUUC-Mor-057152	Magnaporthe oryzae	30.78	0.00e+00	867.00
IUUC-Mpo-057310	Magnaporthe poae	28.90	0.00e+00	888.00
IUUC-Mga-059267	Meleagris gallopavo	30.08	1.00e-55	211.00
IUUC-Mmr-060780	Microcebus murinus	27.05	2.00e-64	240.00
IUUC-Mdo-062308	Monodelphis domestica	27.44	5.00e-64	239.00
IUUC-Mmu-063457	Mus musculus	27.05	2.00e-64	241.00
IUUC-Mpu-066917	Mustela putorius furo	27.70	1.00e-64	241.00
IUUC-Mlu-067696	Myotis lucifugus	27.21	7.00e-65	242.00
IUUC-Ncr-068911	Neurospora crassa	28.83	0.00e+00	900.00
IUUC-Nle-069586	Nomascus leucogenys	27.21	2.00e-64	241.00
IUUC-Opr-071031	Ochotona princeps	28.72	2.00e-46	181.00
IUUC-Ont-072396	Oreochromis niloticus	26.50	3.00e-61	230.00
IUUC-Oan-073147	Ornithorhynchus anatinus	27.24	3.00e-64	240.00
IUUC-Ocu-074324	Oryctolagus cuniculus	27.21	7.00e-65	242.00
IUUC-Ola-086312	Oryzias latipes	26.26	3.00e-61	230.00
IUUC-Oga-088878	Otolemur garnettii	27.21	6.00e-65	242.00
IUUC-Oar-089919	Ovis aries	27.70	1.00e-64	242.00
IUUC-Ptr-090713	Pan troglodytes	27.21	2.00e-64	240.00
IUUC-Pan-091957	Papio anubis	27.05	3.00e-64	240.00
IUUC-Psi-093240	Pelodiscus sinensis	26.76	6.00e-64	239.00
IUUC-Pma-094469	Petromyzon marinus	26.43	1.00e-61	232.00
IUUC-Pno-095059	Phaeosphaeria nodorum	31.31	9.00e-151	527.00
IUUC-Pfo-097159	Poecilia formosa	26.50	5.00e-62	233.00
IUUC-Pab-098003	Pongo abelii	33.86	1.00e-63	238.00
IUUC-Pca-100799	Procavia capensis	26.70	1.00e-56	215.00
IUUC-Pva-103226	Pteropus vampyrus	27.21	1.00e-64	241.00
IUUC-Pte-104235	Pyrenophora teres	30.47	0.00e+00	888.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	32.16	3.00e-174	604.00
IUUC-Rno-105389	Rattus norvegicus	27.05	2.00e-64	240.00
IUUC-Sha-106979	Sarcophilus harrisii	27.44	5.00e-64	239.00
IUUC-Smo-109204	Selaginella moellendorffii	29.08	3.00e-72	266.00
IUUC-Sar-113729	Sorex araneus	27.72	1.00e-53	205.00
IUUC-Ssc-115815	Sus scrofa	27.05	3.00e-64	240.00
IUUC-Tgu-117470	Taeniopygia guttata	27.24	4.00e-64	240.00
IUUC-Tru-118543	Takifugu rubripes	26.48	6.00e-61	229.00
IUUC-Tsy-119165	Tarsius syrichta	29.07	6.00e-49	189.00
IUUC-Tni-119923	Tetraodon nigroviridis	27.94	7.00e-53	202.00
IUUC-Tre-122057	Trichoderma reesei	29.87	0.00e+00	862.00
IUUC-Tvi-122570	Trichoderma virens	28.66	0.00e+00	874.00
IUUC-Tme-127154	Tuber melanosporum	36.03	2.00e-177	614.00
IUUC-Tbe-127801	Tupaia belangeri	34.59	2.00e-55	211.00
IUUC-Ttr-129262	Tursiops truncatus	33.86	1.00e-63	238.00
IUUC-Vda-129686	Verticillium dahliae	36.33	8.00e-147	514.00
IUUC-Vpa-130484	Vicugna pacos	27.21	1.00e-64	242.00
IUUC-Xtr-131769	Xenopus tropicalis	26.63	1.00e-63	238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence