iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092034

Ensembl Protein ID

ENSPANP00000006934.1

UniProt Accession

A0A096N3L7; A0A096N3L7_PAPAN

Genbank Protein ID

ENSPANP00000006934

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01067281

Gene Name

UBE2K

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000014212.1	ENSPANT00000017245.1	ENSPANP00000006934.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.80e-44	150.3	34	157
UBD/Alpha-Helix/UBA	5.60e-11	42.3	172	210

Active Site

Position(s)	Description	Evidence
103	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 13   ppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsves 100
           ++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+ilk  ++W +a+++++
   Q: 34   SKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDILK--DQWAAAMTLRT 119
           67899*******.9***************************************************99********9..*********** PP
   S: 101  vllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 120  VLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 157
           ***********************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+e+l++MGFdr++++ aL + ++++e A+e+Ll+
   Q: 172  EYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLS 210
           6789*********************************97 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

FIFLTSVLRF LSLPCHIETV PSGSTFPIIE YRTSKNQIKV DLVDENFTEL RGEIAGPPDT 60
PYEGGRYQLE IKIPETYPFN PPKVRFITKI WHPNISSVTG AICLDILKDQ WAAAMTLRTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCATTTTCT TAACTTCTGT ACTCAGGTTT CTCTCTCTAC CATGTCATAT TGAAACTGTT 60
CCTTCAGGCA GTACCTTCCC AATTATCGAA TACAGAGTAA GTTCTCGTGA TCGTCTATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0032433--C:filopodium tip
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0035458--P:cellular response to interferon-beta
GO:0010994--P:free ubiquitin chain polymerization
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	66.67	4.00e-25	107.00
IUUC-Aml-001286	Ailuropoda melanoleuca	100.00	1.00e-97	348.00
IUUC-Atr-003063	Amborella trichopoda	51.46	1.00e-37	149.00
IUUC-Apl-004122	Anas platyrhynchos	99.43	9.00e-95	338.00
IUUC-Aca-004565	Anolis carolinensis	98.90	4.00e-98	350.00
IUUC-Aly-006390	Arabidopsis lyrata	50.00	5.00e-42	163.00
IUUC-Ath-006637	Arabidopsis thaliana	48.44	4.00e-39	154.00
IUUC-Acl-008189	Aspergillus clavatus	55.65	7.00e-26	110.00
IUUC-Afl-008489	Aspergillus flavus	44.57	1.00e-26	113.00
IUUC-Afu-008850	Aspergillus fumigatus	42.93	2.00e-26	112.00
IUUC-Ani-009361	Aspergillus nidulans	57.26	2.00e-24	105.00
IUUC-Ang-009548	Aspergillus niger	54.55	1.00e-24	106.00
IUUC-Aor-010105	Aspergillus oryzae	44.57	1.00e-26	113.00
IUUC-Ate-010389	Aspergillus terreus	43.48	9.00e-27	113.00
IUUC-Ame-011454	Astyanax mexicanus	96.65	3.00e-95	340.00
IUUC-Bgr-012255	Blumeria graminis	55.20	3.00e-31	128.00
IUUC-Bta-012992	Bos taurus	100.00	1.00e-97	348.00
IUUC-Bci-013806	Botrytis cinerea	44.15	7.00e-35	140.00
IUUC-Bdi-015024	Brachypodium distachyon	53.61	3.00e-38	150.00
IUUC-Bol-015985	Brassica oleracea	51.72	3.00e-42	164.00
IUUC-Bra-016805	Brassica rapa	51.72	2.00e-42	164.00
IUUC-Cel-018353	Caenorhabditis elegans	52.54	7.00e-50	189.00
IUUC-Cja-019051	Callithrix jacchus	99.44	7.00e-97	345.00
IUUC-Cfa-020016	Canis familiaris	100.00	1.00e-97	348.00
IUUC-Cpo-022026	Cavia porcellus	100.00	1.00e-97	348.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	51.40	2.00e-40	158.00
IUUC-Csa-023059	Chlorocebus sabaeus	100.00	1.00e-97	348.00
IUUC-Cho-024276	Choloepus hoffmanni	96.60	3.00e-73	266.00
IUUC-Cin-025598	Ciona intestinalis	62.64	3.00e-50	191.00
IUUC-Csv-025831	Ciona savignyi	59.07	5.00e-50	190.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	50.75	1.00e-32	132.00
IUUC-Cne-027068	Cryptococcus neoformans	44.63	5.00e-38	150.00
IUUC-Dre-028139	Danio rerio	96.65	3.00e-95	340.00
IUUC-Dno-029169	Dasypus novemcinctus	100.00	5.00e-97	346.00
IUUC-Dor-030382	Dipodomys ordii	84.36	2.00e-76	278.00
IUUC-Dse-031335	Dothistroma septosporum	60.17	3.00e-35	141.00
IUUC-Dme-032003	Drosophila melanogaster	68.79	4.00e-61	227.00
IUUC-Ete-032868	Echinops telfairi	89.94	5.00e-76	276.00
IUUC-Eca-033428	Equus caballus	100.00	1.00e-97	348.00
IUUC-Eeu-035103	Erinaceus europaeus	73.44	5.00e-49	185.00
IUUC-Fca-035366	Felis catus	100.00	1.00e-97	348.00
IUUC-Fal-037016	Ficedula albicollis	100.00	1.00e-97	348.00
IUUC-Fox-037969	Fusarium oxysporum	44.19	8.00e-33	133.00
IUUC-Fso-038296	Fusarium solani	46.11	9.00e-34	136.00
IUUC-Gmo-039135	Gadus morhua	95.53	8.00e-94	335.00
IUUC-Ggr-039768	Gaeumannomyces graminis	50.69	7.00e-24	103.00
IUUC-Gga-041018	Gallus gallus	99.44	2.00e-97	347.00
IUUC-Gac-041503	Gasterosteus aculeatus	96.09	1.00e-94	338.00
IUUC-Gma-042779	Glycine max	52.91	6.00e-41	159.00
IUUC-Ggo-045032	Gorilla gorilla	100.00	1.00e-97	348.00
IUUC-Hsa-046490	Homo sapiens	100.00	1.00e-97	348.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	100.00	1.00e-97	348.00
IUUC-Lch-050588	Latimeria chalumnae	68.25	1.00e-75	275.00
IUUC-Lpe-051070	Leersia perrieri	53.01	3.00e-29	121.00
IUUC-Loc-052549	Lepisosteus oculatus	97.21	1.00e-95	341.00
IUUC-Lma-052949	Leptosphaeria maculans	57.72	2.00e-35	142.00
IUUC-Laf-053688	Loxodonta africana	100.00	2.00e-97	347.00
IUUC-Mcc-055606	Macaca mulatta	100.00	1.00e-97	348.00
IUUC-Mor-056946	Magnaporthe oryzae	41.48	9.00e-22	96.70
IUUC-Mpo-057441	Magnaporthe poae	54.48	1.00e-23	102.00
IUUC-Mtr-058002	Medicago truncatula	52.33	4.00e-41	160.00
IUUC-Mga-059254	Meleagris gallopavo	98.89	3.00e-97	347.00
IUUC-Mvi-060346	Microbotryum violaceum	42.39	7.00e-31	126.00
IUUC-Mmr-061211	Microcebus murinus	100.00	1.00e-97	348.00
IUUC-Mdo-062458	Monodelphis domestica	98.88	3.00e-95	340.00
IUUC-Mmu-063648	Mus musculus	100.00	1.00e-97	348.00
IUUC-Mac-065447	Musa acuminata	53.61	8.00e-39	152.00
IUUC-Mpu-066407	Mustela putorius furo	100.00	3.00e-97	347.00
IUUC-Mlu-067682	Myotis lucifugus	92.82	1.00e-98	352.00
IUUC-Nfi-068517	Neosartorya fischeri	42.93	2.00e-26	112.00
IUUC-Ncr-068749	Neurospora crassa	53.97	2.00e-35	142.00
IUUC-Nle-069712	Nomascus leucogenys	98.34	9.00e-98	348.00
IUUC-Opr-070651	Ochotona princeps	100.00	1.00e-97	348.00
IUUC-Ont-071433	Oreochromis niloticus	96.09	1.00e-94	338.00
IUUC-Oan-073058	Ornithorhynchus anatinus	100.00	2.00e-78	283.00
IUUC-Ocu-074939	Oryctolagus cuniculus	100.00	1.00e-97	348.00
IUUC-Oba-075530	Oryza barthii	53.94	2.00e-29	121.00
IUUC-Obr-076838	Oryza brachyantha	53.99	7.00e-29	120.00
IUUC-Ogl-077606	Oryza glaberrima	53.94	2.00e-29	121.00
IUUC-Ogu-078238	Oryza glumaepatula	53.94	2.00e-29	121.00
IUUC-Oin-079643	Oryza indica	53.94	4.00e-29	120.00
IUUC-Ome-081274	Oryza meridionalis	53.94	2.00e-29	121.00
IUUC-Oni-082651	Oryza nivara	53.94	2.00e-29	121.00
IUUC-Opu-083933	Oryza punctata	53.94	4.00e-29	120.00
IUUC-Oru-085054	Oryza rufipogon	53.94	4.00e-29	120.00
IUUC-Osa-085716	Oryza sativa	53.94	4.00e-29	120.00
IUUC-Ola-087043	Oryzias latipes	96.09	1.00e-94	338.00
IUUC-Olu-087846	Ostreococcus lucimarinus	48.86	8.00e-41	159.00
IUUC-Oga-088897	Otolemur garnettii	99.44	2.00e-97	347.00
IUUC-Oar-089673	Ovis aries	100.00	2.00e-97	347.00
IUUC-Ptr-091295	Pan troglodytes	100.00	1.00e-97	348.00
IUUC-Psi-093498	Pelodiscus sinensis	100.00	1.00e-97	348.00
IUUC-Pma-094115	Petromyzon marinus	87.22	5.00e-85	306.00
IUUC-Pno-095102	Phaeosphaeria nodorum	43.72	2.00e-36	145.00
IUUC-Ppa-095326	Physcomitrella patens	48.85	3.00e-37	147.00
IUUC-Pfo-096940	Poecilia formosa	96.09	1.00e-94	338.00
IUUC-Pab-098279	Pongo abelii	100.00	1.00e-97	348.00
IUUC-Pop-099543	Populus trichocarpa	52.30	4.00e-42	164.00
IUUC-Pca-100782	Procavia capensis	99.44	1.00e-95	342.00
IUUC-Ppe-101789	Prunus persica	52.00	4.00e-36	144.00
IUUC-Pva-102147	Pteropus vampyrus	100.00	3.00e-52	197.00
IUUC-Pte-104370	Pyrenophora teres	56.91	4.00e-35	140.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	44.26	6.00e-35	140.00
IUUC-Rno-104984	Rattus norvegicus	100.00	1.00e-97	348.00
IUUC-Sce-106394	Saccharomyces cerevisiae	45.09	5.00e-33	134.00
IUUC-Sha-106848	Sarcophilus harrisii	98.90	9.00e-98	348.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	46.28	6.00e-38	150.00
IUUC-Smo-109656	Selaginella moellendorffii	49.45	2.00e-38	151.00
IUUC-Sit-110639	Setaria italica	52.41	5.00e-37	147.00
IUUC-Sly-110978	Solanum lycopersicum	52.30	2.00e-42	164.00
IUUC-Stu-112088	Solanum tuberosum	52.30	9.00e-43	166.00
IUUC-Sar-113285	Sorex araneus	84.36	6.00e-76	276.00
IUUC-Sbi-113986	Sorghum bicolor	52.41	6.00e-37	146.00
IUUC-Ssc-116314	Sus scrofa	100.00	1.00e-97	348.00
IUUC-Tgu-117427	Taeniopygia guttata	99.44	1.00e-97	348.00
IUUC-Tru-118618	Takifugu rubripes	91.06	7.00e-90	322.00
IUUC-Tsy-119208	Tarsius syrichta	100.00	7.00e-98	349.00
IUUC-Tni-119667	Tetraodon nigroviridis	96.65	4.00e-95	340.00
IUUC-Tca-121446	Theobroma cacao	52.87	2.00e-42	165.00
IUUC-Tre-122053	Trichoderma reesei	39.88	1.00e-29	122.00
IUUC-Tae-125119	Triticum aestivum	54.22	8.00e-31	126.00
IUUC-Tme-127024	Tuber melanosporum	54.35	2.00e-37	149.00
IUUC-Tbe-127752	Tupaia belangeri	100.00	2.00e-97	347.00
IUUC-Ttr-128287	Tursiops truncatus	100.00	3.00e-97	347.00
IUUC-Vda-129947	Verticillium dahliae	42.20	2.00e-30	125.00
IUUC-Vpa-130481	Vicugna pacos	100.00	1.00e-97	348.00
IUUC-Vvi-131429	Vitis vinifera	50.29	6.00e-39	153.00
IUUC-Xtr-132710	Xenopus tropicalis	81.77	2.00e-83	301.00
IUUC-Xma-134308	Xiphophorus maculatus	95.53	3.00e-94	337.00
IUUC-Zma-135733	Zea mays	51.12	2.00e-35	141.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence