iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009441

Ensembl Protein ID

CADANIAP00000511

UniProt Accession

Q5AWA8; C8VB94; Q5AWA8_EMENI

Genbank Protein ID

CBF79349.1; EAA62002.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

BN001304; AACD01000129

Gene Name

ANIA_07422; AN7422.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00000511	CADANIAT00000511	CADANIAP00000511

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.80e-54	182.6	219	696
UBD/Alpha-Helix/UBA	1.30e-21	75.1	503	540

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel..................w.kskkkavsprell 74
           tGl+NlgN+CY+ Sv+QcL+ +pe+++ + +  +e+ +    ++p +++ ++l+kl                      +  +++k  +p++++
   Q: 219  TGLSNLGNSCYLSSVVQCLFDLPEFQRRYYH-PNEDPPLA--ETPAADFETQLRKLADGTlsgrysrpddktvaspkpQeIRHQKGLAPSMFK 308
           7******************************.33333333..57888888888888888845555555444444333313555559******* PP
   S: 75   kalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           + +++ ++efs+++qqDa Efl ++++++  +                           ++   +++i d F+++++++++cl+c+ v  r +
   Q: 309  HLIGRDHPEFSTMRQQDAFEFLLHVFKHVTLSK--------------------------HPVGMDNPI-DSFKFSIEQRLQCLKCRGVRYRLD 374
           *************************99876443..........................566666665.78********************** PP
   S: 168  pfldlslpvpgkeetkke...........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksreki 249
           +   +s+pvp ++  + e           +l dcL++ft+ e+++    + c +c+++ + +k+  ++++P  L+++  Rf  +  +++++k+
   Q: 375  EQDNISIPVPARRVPDSEgsnsdgsfesvTLYDCLDAFTADETVD----LRCAHCNSQEKFSKRSAFRTMPAELVINARRF--ELINWVPTKL 461
           **********999988889999**********************9....9*******************************..6677****** PP
   S: 250  nkkvefple.Ldlspfcts.......................................................................... 267
           +  ve+ +  +dls ++++                                                                          
   Q: 462  DIPVEVEDApIDLSCYLSTgpgegedllpedeetggfevnmdtlnqllamgfprvrcekalystgnsdaeaamnwllshmddpdidepvhkkr 554
           *****************9999999999988888888888888888888888888887777777777777777777777777766666666666 PP
   S: 268  ...........peekqke...............................................................kkkYeLiavvvH 286
                            +                                                               + +Y+L ++++H
   Q: 555  vsefganeqdlA-----KiaqlgdmgiddsrarkaltatggdinraidwvfshpgdedessvheppsgnadtsvvpgfatsPATYQLRSIICH 642
           666665555550.....0555555555555555556666666666666666666666666777788888889999999999************ PP
   S: 287  sG.slssGHYvayvkn.....ekgk..WllfdDskVtevkeeevleetgstaYvlfYkr 337
           +G s++ GHYva+v++     +  +  W+ f+D+kV ev  ++v+e++ + aY++f+ r
   Q: 643  KGaSVHAGHYVAFVRKhlpgkS--GlsWVMFNDEKVVEV--DDVQEMK-KFAYLYFFSR 696
           ****************766433..257***********9..5777744.89*****987 PP

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           d l+ql +MGF+r ++ +aL ++ n ++eaA+++Ll++
   Q: 503  DTLNQLLAMGFPRVRCEKALYSTgNSDAEAAMNWLLSH 540
           579*********************************97 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MIYLNYGHRL PLKPFIEKTR EEPPHKISKL AINAETDEDR YDTSTRVVCY SCGRDDVGEP 60
SGKLQSVIEG VMHATTFSKR EEIKAWEQEF IPCEHTTGLI QQESKRIKSQ GCGRSQFGGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTTACC TGGTGCGTTC AGCACTCCAA TCTTCATGGC CATAAGCAAG CCAAGCTAAC 60
TCTATTGCAG AACTACGGCC ACCGTCTGCC TCTCAAGCCG TTTATCGAGA AGACTGTACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ani:AN7422.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	33.99	2.00e-84	305.00
IUUC-Aml-002104	Ailuropoda melanoleuca	33.67	1.00e-106	379.00
IUUC-Atr-002580	Amborella trichopoda	36.66	1.00e-94	339.00
IUUC-Apl-003774	Anas platyrhynchos	34.06	2.00e-108	385.00
IUUC-Aca-005368	Anolis carolinensis	34.66	9.00e-109	386.00
IUUC-Aly-005727	Arabidopsis lyrata	34.88	6.00e-98	350.00
IUUC-Ath-006974	Arabidopsis thaliana	34.26	4.00e-99	353.00
IUUC-Ago-007890	Ashbya gossypii	33.93	1.00e-87	315.00
IUUC-Acl-008057	Aspergillus clavatus	64.33	0.00e+00	941.00
IUUC-Afl-008547	Aspergillus flavus	64.33	0.00e+00	874.00
IUUC-Afu-008805	Aspergillus fumigatus	64.96	0.00e+00	949.00
IUUC-Ang-009720	Aspergillus niger	65.30	0.00e+00	924.00
IUUC-Aor-010111	Aspergillus oryzae	63.76	0.00e+00	947.00
IUUC-Ate-010531	Aspergillus terreus	57.91	0.00e+00	809.00
IUUC-Ame-011893	Astyanax mexicanus	33.68	6.00e-87	313.00
IUUC-Bgr-012183	Blumeria graminis	50.91	0.00e+00	709.00
IUUC-Bta-013179	Bos taurus	33.88	1.00e-106	379.00
IUUC-Bci-013858	Botrytis cinerea	55.93	0.00e+00	796.00
IUUC-Bdi-014904	Brachypodium distachyon	35.64	7.00e-91	327.00
IUUC-Bol-015296	Brassica oleracea	34.88	1.00e-97	349.00
IUUC-Bra-017619	Brassica rapa	34.97	2.00e-98	352.00
IUUC-Cel-018625	Caenorhabditis elegans	32.03	1.00e-66	246.00
IUUC-Cja-019063	Callithrix jacchus	33.21	4.00e-104	370.00
IUUC-Cfa-020976	Canis familiaris	34.25	1.00e-109	389.00
IUUC-Cpo-022265	Cavia porcellus	34.51	8.00e-110	389.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	31.11	2.00e-59	221.00
IUUC-Csa-024177	Chlorocebus sabaeus	33.86	2.00e-96	345.00
IUUC-Cho-024702	Choloepus hoffmanni	32.93	6.00e-77	280.00
IUUC-Cin-025411	Ciona intestinalis	31.57	6.00e-91	327.00
IUUC-Csv-026347	Ciona savignyi	31.65	7.00e-86	310.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	53.53	0.00e+00	706.00
IUUC-Cne-026831	Cryptococcus neoformans	43.28	3.00e-153	533.00
IUUC-Cme-027335	Cyanidioschyzon merolae	30.14	1.00e-65	243.00
IUUC-Dre-027651	Danio rerio	32.07	3.00e-98	351.00
IUUC-Dno-029034	Dasypus novemcinctus	33.88	7.00e-108	383.00
IUUC-Dor-030479	Dipodomys ordii	35.23	7.00e-54	203.00
IUUC-Dse-031467	Dothistroma septosporum	49.13	0.00e+00	676.00
IUUC-Dme-032075	Drosophila melanogaster	36.26	1.00e-101	362.00
IUUC-Ete-032865	Echinops telfairi	31.00	4.00e-85	307.00
IUUC-Eca-034059	Equus caballus	33.93	8.00e-108	382.00
IUUC-Eeu-035304	Erinaceus europaeus	36.82	2.00e-105	374.00
IUUC-Fca-035515	Felis catus	33.88	4.00e-108	384.00
IUUC-Fal-037271	Ficedula albicollis	34.57	2.00e-107	381.00
IUUC-Fox-037745	Fusarium oxysporum	55.01	0.00e+00	761.00
IUUC-Fso-038158	Fusarium solani	54.74	0.00e+00	763.00
IUUC-Gmo-039071	Gadus morhua	33.07	2.00e-93	335.00
IUUC-Ggr-040098	Gaeumannomyces graminis	52.45	0.00e+00	704.00
IUUC-Gga-040635	Gallus gallus	33.93	6.00e-109	386.00
IUUC-Gac-042528	Gasterosteus aculeatus	33.07	4.00e-95	340.00
IUUC-Gma-043614	Glycine max	34.98	2.00e-100	358.00
IUUC-Ggo-044602	Gorilla gorilla	33.72	3.00e-107	381.00
IUUC-Hsa-045959	Homo sapiens	33.72	3.00e-107	381.00
IUUC-Hvu-047563	Hordeum vulgare	36.61	2.00e-93	334.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	33.97	2.00e-108	385.00
IUUC-Kpa-049156	Komagataella pastoris	40.46	7.00e-147	512.00
IUUC-Lch-049648	Latimeria chalumnae	33.48	8.00e-97	346.00
IUUC-Lpe-051523	Leersia perrieri	34.19	3.00e-91	327.00
IUUC-Loc-052072	Lepisosteus oculatus	32.82	1.00e-95	342.00
IUUC-Lma-053216	Leptosphaeria maculans	54.97	0.00e+00	765.00
IUUC-Laf-054327	Loxodonta africana	33.67	5.00e-107	380.00
IUUC-Mcc-055443	Macaca mulatta	33.88	2.00e-107	382.00
IUUC-Meu-056298	Macropus eugenii	33.33	2.00e-65	242.00
IUUC-Mor-057106	Magnaporthe oryzae	52.79	0.00e+00	729.00
IUUC-Mpo-057589	Magnaporthe poae	53.31	0.00e+00	712.00
IUUC-Mtr-058680	Medicago truncatula	38.14	3.00e-102	364.00
IUUC-Mla-058903	Melampsora laricipopulina	40.13	5.00e-152	529.00
IUUC-Mga-059669	Meleagris gallopavo	33.98	2.00e-104	371.00
IUUC-Mvi-060476	Microbotryum violaceum	39.81	6.00e-141	493.00
IUUC-Mmr-060575	Microcebus murinus	33.76	2.00e-107	381.00
IUUC-Mdo-062183	Monodelphis domestica	33.59	2.00e-108	385.00
IUUC-Mmu-063592	Mus musculus	34.01	3.00e-108	384.00
IUUC-Mac-065634	Musa acuminata	34.03	7.00e-84	303.00
IUUC-Mpu-066082	Mustela putorius furo	33.63	4.00e-109	387.00
IUUC-Mlu-067345	Myotis lucifugus	33.04	3.00e-105	374.00
IUUC-Nfi-068558	Neosartorya fischeri	64.08	0.00e+00	960.00
IUUC-Ncr-068960	Neurospora crassa	54.25	0.00e+00	707.00
IUUC-Nle-070173	Nomascus leucogenys	33.95	3.00e-108	384.00
IUUC-Opr-070556	Ochotona princeps	33.88	5.00e-108	383.00
IUUC-Ont-071502	Oreochromis niloticus	33.51	1.00e-96	345.00
IUUC-Oan-072959	Ornithorhynchus anatinus	37.71	2.00e-38	150.00
IUUC-Ocu-074861	Oryctolagus cuniculus	34.12	7.00e-109	386.00
IUUC-Oba-075109	Oryza barthii	37.18	1.00e-93	335.00
IUUC-Obr-076292	Oryza brachyantha	33.94	7.00e-90	323.00
IUUC-Ogl-077065	Oryza glaberrima	38.39	3.00e-99	354.00
IUUC-Ogu-078776	Oryza glumaepatula	36.64	4.00e-96	343.00
IUUC-Oin-080048	Oryza indica	37.86	3.00e-98	351.00
IUUC-Olo-080711	Oryza longistaminata	36.13	3.00e-89	321.00
IUUC-Ome-081506	Oryza meridionalis	36.64	7.00e-92	329.00
IUUC-Oni-082320	Oryza nivara	37.34	1.00e-93	336.00
IUUC-Opu-083801	Oryza punctata	33.95	4.00e-87	314.00
IUUC-Oru-085139	Oryza rufipogon	37.18	9.00e-94	336.00
IUUC-Osa-085713	Oryza sativa	38.55	3.00e-100	357.00
IUUC-Ola-086951	Oryzias latipes	32.14	1.00e-91	329.00
IUUC-Olu-087822	Ostreococcus lucimarinus	30.21	3.00e-82	298.00
IUUC-Oga-088625	Otolemur garnettii	33.59	4.00e-107	380.00
IUUC-Oar-089995	Ovis aries	33.76	7.00e-106	376.00
IUUC-Ptr-090640	Pan troglodytes	34.68	6.00e-111	393.00
IUUC-Pan-091974	Papio anubis	33.63	1.00e-106	379.00
IUUC-Psi-093957	Pelodiscus sinensis	33.54	7.00e-109	386.00
IUUC-Pma-094242	Petromyzon marinus	37.21	1.00e-65	241.00
IUUC-Pno-094835	Phaeosphaeria nodorum	54.36	0.00e+00	785.00
IUUC-Ppa-095901	Physcomitrella patens	35.31	6.00e-110	390.00
IUUC-Pfo-097148	Poecilia formosa	33.25	2.00e-97	348.00
IUUC-Pab-098068	Pongo abelii	33.16	1.00e-96	345.00
IUUC-Pop-098855	Populus trichocarpa	38.39	2.00e-100	358.00
IUUC-Pca-100738	Procavia capensis	34.85	4.00e-91	327.00
IUUC-Ppe-101315	Prunus persica	35.11	2.00e-97	348.00
IUUC-Pva-102154	Pteropus vampyrus	33.72	2.00e-106	378.00
IUUC-Pgr-103343	Puccinia graminis	39.44	5.00e-115	406.00
IUUC-Ptt-103928	Puccinia triticina	33.81	3.00e-107	380.00
IUUC-Pte-104306	Pyrenophora teres	53.60	0.00e+00	750.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	54.36	0.00e+00	772.00
IUUC-Rno-105801	Rattus norvegicus	33.97	1.00e-108	385.00
IUUC-Sce-106304	Saccharomyces cerevisiae	33.28	3.00e-96	344.00
IUUC-Sha-107635	Sarcophilus harrisii	33.47	1.00e-107	382.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	39.53	5.00e-143	499.00
IUUC-Spo-108144	Schizosaccharomyces pombe	38.99	2.00e-140	491.00
IUUC-Smo-108703	Selaginella moellendorffii	35.78	4.00e-99	354.00
IUUC-Sit-110728	Setaria italica	34.56	5.00e-101	360.00
IUUC-Sly-111523	Solanum lycopersicum	38.72	6.00e-107	380.00
IUUC-Sar-113733	Sorex araneus	36.60	7.00e-49	187.00
IUUC-Sbi-114419	Sorghum bicolor	35.13	3.00e-99	354.00
IUUC-Sre-115225	Sporisorium reilianum	40.51	9.00e-143	499.00
IUUC-Ssc-115686	Sus scrofa	33.84	2.00e-107	382.00
IUUC-Tgu-117346	Taeniopygia guttata	34.02	6.00e-104	370.00
IUUC-Tru-118627	Takifugu rubripes	32.71	3.00e-96	345.00
IUUC-Tsy-119278	Tarsius syrichta	29.03	7.00e-81	293.00
IUUC-Tni-120658	Tetraodon nigroviridis	31.63	6.00e-86	310.00
IUUC-Tca-121585	Theobroma cacao	36.89	2.00e-94	338.00
IUUC-Tre-122043	Trichoderma reesei	52.84	0.00e+00	699.00
IUUC-Tvi-122303	Trichoderma virens	51.51	0.00e+00	700.00
IUUC-Tae-123798	Triticum aestivum	37.22	3.00e-97	347.00
IUUC-Tur-126732	Triticum urartu	31.71	2.00e-83	302.00
IUUC-Tme-126909	Tuber melanosporum	53.51	0.00e+00	748.00
IUUC-Tbe-127261	Tupaia belangeri	31.17	7.00e-72	263.00
IUUC-Ttr-128295	Tursiops truncatus	30.08	1.00e-72	266.00
IUUC-Uma-129599	Ustilago maydis	40.65	1.00e-148	518.00
IUUC-Vda-129688	Verticillium dahliae	53.32	0.00e+00	720.00
IUUC-Vpa-130170	Vicugna pacos	26.74	2.00e-67	248.00
IUUC-Vvi-131116	Vitis vinifera	34.46	3.00e-97	347.00
IUUC-Xtr-131953	Xenopus tropicalis	34.77	2.00e-97	348.00
IUUC-Xma-133837	Xiphophorus maculatus	33.11	2.00e-97	348.00
IUUC-Yli-134510	Yarrowia lipolytica	43.53	2.00e-148	518.00
IUUC-Zma-135786	Zea mays	35.36	2.00e-96	344.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence