iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091300

UUCD1 version

UUC-PaT-00056

Ensembl Protein ID

ENSPTRP00000044766.4

UniProt Accession

B0F4N0; B0F4N0_PANTR

Genbank Protein ID

ABV69901.1; JAA07232.1; JAA18766.1; JAA26976.1

Protein Name

TRIM22; Tripartite motif containing 22

Genbank Nucleotide ID

AACZ03079423; GABC01004106; GABF01003379; GABD01006124

Gene Name

TRIM22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000003259.6	ENSPTRT00000048054.4	ENSPTRP00000044766.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.50e-09	38.2	15	60
E3 activity/RING/U-box	2.10e-07	30.9	9	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle + + pl+l+CgH f++ C+  k++ +   s++e +CP+C+
   Q: 15   CPICLELLTE-PLSLDCGHSFCQACItTKIKESVIISRGESSCPVCQ 60
           ********99.***************877799999***********7 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwl......asggktcPvtrqplteedlvPnltlrrliq 66
           + +e  CpI lel ++P  l +G+++ +++I   +      ++g+++cPv+++++++ +l Pn  l ++++
   Q: 9    IEKEVTCPICLELLTEPLSLDCGHSFCQACITTKIkesviiSRGESSCPVCQTRFQPGNLRPNRHLANIVE 79
           567899*************************999955555566666******************9988776 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDFSVKVDIE KEVTCPICLE LLTEPLSLDC GHSFCQACIT TKIKESVIIS RGESSCPVCQ 60
TRFQPGNLRP NRHLANIVER VKEVKMSPQE GQKRDVCEPH GKKLQIFCKE DGKVICWVCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGTATTCTT GCTTGAGTAA ACCACACTAA GAATAAGGAA GTAGTGACTG AGTGCCTTGC 60
CAGTACAGCA GATGCTAGAA CATAATGTAG CATTACTATT CCCCAGGGTT TATTGTTATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0008270--F:zinc ion binding
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0070206--P:protein trimerization
GO:0032880--P:regulation of protein localization

KEGG

ptr:450985

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002371	Ailuropoda melanoleuca	67.47	0.00e+00	697.00
IUUC-Acl-008013	Aspergillus clavatus	58.82	3.00e-06	47.80
IUUC-Ani-009293	Aspergillus nidulans	60.61	6.00e-06	46.60
IUUC-Cfa-021080	Canis familiaris	66.06	0.00e+00	675.00
IUUC-Cre-022597	Chlamydomonas reinhardtii	33.75	1.00e-09	57.80
IUUC-Csa-023785	Chlorocebus sabaeus	89.56	0.00e+00	899.00
IUUC-Eca-034336	Equus caballus	67.20	0.00e+00	637.00
IUUC-Ggo-044550	Gorilla gorilla	97.99	0.00e+00	950.00
IUUC-Hsa-046363	Homo sapiens	99.00	0.00e+00	993.00
IUUC-Laf-053647	Loxodonta africana	65.26	0.00e+00	635.00
IUUC-Mcc-054743	Macaca mulatta	90.96	0.00e+00	916.00
IUUC-Mpu-066674	Mustela putorius furo	65.26	0.00e+00	677.00
IUUC-Nle-068980	Nomascus leucogenys	97.19	0.00e+00	976.00
IUUC-Pan-092605	Papio anubis	81.33	0.00e+00	785.00
IUUC-Pab-098535	Pongo abelii	98.59	0.00e+00	989.00
IUUC-Tsy-119330	Tarsius syrichta	75.70	0.00e+00	727.00
IUUC-Tur-126362	Triticum urartu	37.88	4.00e-07	48.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence