iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000144

Ensembl Protein ID

EMT14565

UniProt Accession

N1R2Z5; N1R2Z5_AEGTA

Genbank Protein ID

EMT14565.1

Protein Name

Ubiquitin-activating enzyme E1 3

Genbank Nucleotide ID

KD543396

Gene Name

F775_16673

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_16673	EMT14565	EMT14565

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.70e-163	544.3	386	873

Active Site

Position(s)	Description	Evidence
567	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahees 96
           YD Q+ ++G++ q+k+++a+ ++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa a++ +np+  ++a +++
   Q: 386  YDAQVSVFGSKLQKKMEEANTFVVGSGALGCEFLKNLALMGVscsskGKLTITDDDIIEKSNLSRQFLFRDWNIGQAKSTVAATAANAINPSLYIDALQNR 486
           ***************************************************************************************************** PP
   S: 97   iteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.... 190
            ++++e+++   F + +dvV++aldn+ ar++++ +cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa    
   Q: 487  ACPDTENVFhdtFWEGLDVVINALDNVNARMYMDMRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArsef 587
           *******8899999999************************************************************************************ PP
   S: 191  ........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv......... 274
                     +n +l++ a+      k   ++ +e +++v++ l++ + ++f+++i++a+ +f+ +++n +kql+  f+ d  t+ ++pfw+         
   Q: 588  egllektpNEVNSFLSNPAQYAAAMRKAGDAQARELLERVSECLNKDRCSTFDDCISWARLKFEDYFSNRVKQLTFTFPEDAATSMGAPFWSapkrfpral 688
           *******99999999999999999999*****************************************************************9*****999 PP
   S: 275  .............................................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekk..kgrkpgel 323
                                                         +++++ ++ v+  ++++  ++++++      ++ ll++l++ +k+  +g +++ +
   Q: 689  qfsaadqshlnfimsasilraesfgvaipewakntskladvvqkiIVPTFEPKQGVNIVTDEKASNLSSTSVddvavIEDLLAKLQEYAKRlpPGFQMKPI 789
           999999999999999999999999999998888777666666666333333333333333333333333322455677778888888887655899***** PP
   S: 324  sfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           +fekddd   ++dl+  +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv+ g  + e ++n+f ++a+
   Q: 790  QFEKDDDTnfHMDLISGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVMAGehPVEDYRNTFANLAL 873
           ******************************.**************************************999999*****99875 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MRRLFASDVL VSGLNGLGAE IAKNLALAGV KSVTIHDVKN VEMWDLSGNF FLSEDDIGKN 60
RAAACVAKLQ ELNNAVLISA LTEELTMEHL SKFQAVVFTD IGLDKAYEFD YYCHNHQPPI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGCCGCC TCTTCGCCTC CGACGTCCTC GTCTCCGGGC TCAACGGGCT CGGCGCTGAA 60
ATTGGTTCGC CTGCTAGTCC CTTCTCCGCC TGCCATTTTT TGTTTATTAG TTTGTTCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

ats:F775_16673

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bdi-014009	Brachypodium distachyon	89.30	0.00e+00	1759.00
IUUC-Dse-031524	Dothistroma septosporum	43.95	0.00e+00	813.00
IUUC-Eeu-035323	Erinaceus europaeus	40.96	8.00e-152	530.00
IUUC-Hvu-047191	Hordeum vulgare	97.88	0.00e+00	1999.00
IUUC-Lpe-051299	Leersia perrieri	88.70	0.00e+00	1808.00
IUUC-Mvi-060437	Microbotryum violaceum	43.34	0.00e+00	798.00
IUUC-Oba-075934	Oryza barthii	89.10	0.00e+00	1816.00
IUUC-Obr-076244	Oryza brachyantha	87.69	0.00e+00	1748.00
IUUC-Ogl-077762	Oryza glaberrima	89.10	0.00e+00	1815.00
IUUC-Ogu-078305	Oryza glumaepatula	88.90	0.00e+00	1815.00
IUUC-Oin-080154	Oryza indica	89.10	0.00e+00	1815.00
IUUC-Olo-081089	Oryza longistaminata	89.30	0.00e+00	1820.00
IUUC-Ome-081171	Oryza meridionalis	82.85	0.00e+00	1692.00
IUUC-Oni-082447	Oryza nivara	89.00	0.00e+00	1815.00
IUUC-Opu-083863	Oryza punctata	88.29	0.00e+00	1800.00
IUUC-Oru-084469	Oryza rufipogon	89.20	0.00e+00	1818.00
IUUC-Osa-085625	Oryza sativa	89.20	0.00e+00	1815.00
IUUC-Sit-110294	Setaria italica	87.69	0.00e+00	1829.00
IUUC-Sbi-114774	Sorghum bicolor	88.80	0.00e+00	1846.00
IUUC-Tsy-119436	Tarsius syrichta	35.01	1.00e-163	570.00
IUUC-Tae-125676	Triticum aestivum	99.50	0.00e+00	2019.00
IUUC-Tur-126011	Triticum urartu	95.39	0.00e+00	1977.00
IUUC-Tbe-127714	Tupaia belangeri	36.39	6.00e-138	484.00
IUUC-Vpa-130716	Vicugna pacos	38.01	0.00e+00	662.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence