iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-110294

Ensembl Protein ID

Si028779m

UniProt Accession

K3ZQ99; K3ZQ99_SETIT

Genbank Protein ID

KQL27290.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CM003529

Gene Name

LOC101784654; SETIT_028779mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si028779m.g	Si028779m	Si028779m

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.40e-172	575.5	456	943

Active Site

Position(s)	Description	Evidence
637	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahee 95
           YD Qi ++G++ q+kl+ a++++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa+a+  +np+ +++a ++
   Q: 456  YDAQISVFGSKLQKKLQDANIFVVGSGALGCEFLKNLALMGVscsskGKLTITDDDAIEKSNLSRQFLFRDWNIGQAKSIVAAAAASTINPSLQIDALQN 555
           **************************************************************************************************** PP
   S: 96   siteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           + ++++e+++   F + ++vV++aldn+ ar++++ +cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa  
   Q: 556  RACPDTENVFhdtFWDGLNVVINALDNVNARMYMDMRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArs 655
           ********9899999999********************************************************************************** PP
   S: 191  ..........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv...... 274
                       +n +l++ a+      k   ++ +e +++v++ l +e+  +fe++i++a+  f+ +++n +kql+  f+ d  t+ ++pfw+      
   Q: 656  efegllektpNEVNSFLSNPAQYAAAMRKAGDAQARELLERVSECLGKERCITFEDCITWARLRFEDYFSNRVKQLTFTFPEDASTSTGTPFWSapkrfp 755
           ********999999999999999999999*********************************************************************** PP
   S: 275  ...................................................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekk..k 316
                                                              +   ++ ++ v+  ++++ +++++++      +  ll +le+ +k+  +
   Q: 756  rplqfsatdssqihfimsasilraesfgiaipdwakntsnlaeavnkvavpE---FKPKKGVNIVTDEKATNLSSTSVddvavIDELLSKLEECAKNlpP 852
           ********************************99997776666665553332...222222332222222222222224456799999****99998668 PP
   S: 317  grkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           g +++ ++fekddd   ++dl+  +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv+ g  + e ++n+f ++a+
   Q: 853  GFQMKPIQFEKDDDTnfHMDLISGFANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVIAGehPIEDYRNTFANLAL 943
           9************************************.**************************************999999*****99875 PP

Organism

Setaria italica

Protein Sequence
(Fasta)

MRCLRLLRRG FLSMLPSKRS AGADGGQPKR SKVGESPPAA TASNGSRNGA PPEIDEDLHS 60
RQLAVYGRET MRRLFASDVL VSGLNGLGAE IAKNLALAGV RSVTIHDAKN VDMWDLSANF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGTGCT TACGGTTGCT GCGCAGGGGC TTCCTCTCCA TGCTCCCATC CAAGAGGTCC 60
GCGGGCGCCG ACGGCGGCCA GCCCAAGAGG TCCAAGGTTG GGGAATCGCC GCCCGCCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

sita:101784654

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000144	Aegilops tauschii	87.69	0.00e+00	1819.00
IUUC-Ago-007873	Ashbya gossypii	46.67	0.00e+00	843.00
IUUC-Bdi-014009	Brachypodium distachyon	85.40	0.00e+00	1769.00
IUUC-Cme-027290	Cyanidioschyzon merolae	38.65	0.00e+00	701.00
IUUC-Dse-031524	Dothistroma septosporum	43.29	0.00e+00	820.00
IUUC-Hvu-047191	Hordeum vulgare	87.59	0.00e+00	1815.00
IUUC-Lpe-051299	Leersia perrieri	87.80	0.00e+00	1877.00
IUUC-Mvi-060437	Microbotryum violaceum	43.96	0.00e+00	833.00
IUUC-Oba-075934	Oryza barthii	87.81	0.00e+00	1877.00
IUUC-Obr-076244	Oryza brachyantha	86.47	0.00e+00	1796.00
IUUC-Ogl-077762	Oryza glaberrima	87.77	0.00e+00	1900.00
IUUC-Ogu-078305	Oryza glumaepatula	87.71	0.00e+00	1877.00
IUUC-Oin-080154	Oryza indica	87.86	0.00e+00	1900.00
IUUC-Olo-081089	Oryza longistaminata	88.15	0.00e+00	1909.00
IUUC-Oni-082447	Oryza nivara	87.97	0.00e+00	1885.00
IUUC-Opu-083863	Oryza punctata	89.13	0.00e+00	1865.00
IUUC-Oru-084469	Oryza rufipogon	88.00	0.00e+00	1880.00
IUUC-Osa-085625	Oryza sativa	88.35	0.00e+00	1884.00
IUUC-Pno-095154	Phaeosphaeria nodorum	42.86	0.00e+00	849.00
IUUC-Sbi-114774	Sorghum bicolor	92.68	0.00e+00	2049.00
IUUC-Tae-125702	Triticum aestivum	85.69	0.00e+00	1877.00
IUUC-Tur-126011	Triticum urartu	85.08	0.00e+00	1796.00
IUUC-Vpa-130716	Vicugna pacos	38.94	0.00e+00	676.00
IUUC-Xtr-132026	Xenopus tropicalis	38.61	0.00e+00	631.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence