iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036892

Ensembl Protein ID

ENSFALP00000011461.1

UniProt Accession

U3K8V7; U3K8V7_FICAL

Genbank Protein ID

ENSFALP00000011461

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AGTO01000007

Gene Name

FRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000010983.1	ENSFALT00000011507.1	ENSFALP00000011461.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.10e-11	41.6	81	141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk........elegkrGlfPenFve 60
           + +l+dyea ++d+L++++G++++v+      egW++++           ++  G +P+n+++
   Q: 81   FVALFDYEARTEDDLSFRAGEKLEVL--SASHEGWWYAKLllpegsvcPGRKIAGYIPANYIA 141
           679***********************..78889*****8899999988888889*******96 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MGNFFRKHCP WLERYLPCLF FGRNGEQEDK GGQVFANLAA VKPDLQAGQK DLAGQTDLES 60
KIKEKPLPPL PGQNLANICS FVALFDYEAR TEDDLSFRAG EKLEVLSASH EGWWYAKLLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGACCACA TCTGAGATAA GAAAACACCC ATCCCAAGCA GAAGGAATTG AAAAGCCTCC 60
CTTATTTACA TGTTCTGGCT TTATTGTTTT GCTGTAACAG AAGAGTCTCC ACACTTTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000727	Aegilops tauschii	28.77	4.00e-21	96.70
IUUC-Apl-003394	Anas platyrhynchos	73.09	0.00e+00	779.00
IUUC-Aca-004553	Anolis carolinensis	66.73	0.00e+00	706.00
IUUC-Cja-019885	Callithrix jacchus	74.83	0.00e+00	703.00
IUUC-Cre-022669	Chlamydomonas reinhardtii	30.21	1.00e-22	100.00
IUUC-Dre-028274	Danio rerio	58.92	1.00e-164	572.00
IUUC-Dno-029689	Dasypus novemcinctus	73.81	0.00e+00	689.00
IUUC-Dme-031976	Drosophila melanogaster	61.11	3.00e-168	584.00
IUUC-Eeu-034770	Erinaceus europaeus	58.79	4.00e-137	481.00
IUUC-Gga-041072	Gallus gallus	79.73	0.00e+00	840.00
IUUC-Hvu-047815	Hordeum vulgare	28.07	5.00e-21	96.30
IUUC-Loc-052913	Lepisosteus oculatus	59.45	7.00e-172	596.00
IUUC-Mga-059456	Meleagris gallopavo	77.25	0.00e+00	811.00
IUUC-Mmr-061480	Microcebus murinus	72.46	0.00e+00	677.00
IUUC-Mlu-067167	Myotis lucifugus	74.72	0.00e+00	685.00
IUUC-Nle-069786	Nomascus leucogenys	65.52	0.00e+00	698.00
IUUC-Ont-072417	Oreochromis niloticus	61.87	1.00e-168	585.00
IUUC-Ola-086419	Oryzias latipes	60.04	9.00e-168	583.00
IUUC-Pan-092732	Papio anubis	71.73	0.00e+00	698.00
IUUC-Psi-093899	Pelodiscus sinensis	70.11	0.00e+00	746.00
IUUC-Pma-094230	Petromyzon marinus	59.55	8.00e-160	556.00
IUUC-Pfo-096035	Poecilia formosa	60.30	1.00e-165	576.00
IUUC-Rno-105269	Rattus norvegicus	73.29	0.00e+00	691.00
IUUC-Tgu-116491	Taeniopygia guttata	89.07	0.00e+00	905.00
IUUC-Tru-117795	Takifugu rubripes	57.42	3.00e-151	528.00
IUUC-Tni-120512	Tetraodon nigroviridis	58.08	4.00e-170	590.00
IUUC-Tae-124547	Triticum aestivum	28.77	3.00e-21	97.10
IUUC-Tur-126643	Triticum urartu	27.27	1.00e-20	94.70
IUUC-Ttr-128817	Tursiops truncatus	73.03	0.00e+00	685.00
IUUC-Vpa-130389	Vicugna pacos	62.14	0.00e+00	629.00
IUUC-Xtr-132360	Xenopus tropicalis	56.39	4.00e-176	610.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence