iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpo-057435

Ensembl Protein ID

MAPG_01107T0

UniProt Accession

A0A0C4DMU4; A0A0C4DMU4_MAGP6

Genbank Protein ID

KLU82028.1

Protein Name

Ubiquitin-activating enzyme E1 1

Genbank Nucleotide ID

ADBL01000257

Gene Name

MAPG_01107

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MAPG_01107	MAPG_01107T0	MAPG_01107T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.30e-183	610.0	428	913

Active Site

Position(s)	Description	Evidence
611	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn..v 90
           YD+Qi+++G ++q+k+ + k +lvGag++GcE+lKn +++G+     g+i ++Dmd +e+snlnrqFLfr++dvg+ K+++aa+a+  +np  +  +
   Q: 428  YDGQIAVFGKQYQDKVANMKQFLVGAGAIGCEMLKNWAMIGLgtgpeGKIVITDMDSIEKSNLNRQFLFRPKDVGQMKSDCAAKAAELMNPELSghI 524
           ********************************************************************************************97225 PP
   S: 91   eaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaae 184
           +  ++++++++e+i+   F   +d+V +aldn+ear++v+r+c+  ++pl+esgtlG++G+++v++++lte+ys+s+dpp++++P+ctl+++pn++e
   Q: 525  VCLKDRVSPETEHIFneeFWGGLDGVTNALDNVEARTYVDRRCVFFHKPLLESGTLGTKGNTQVVLPKLTESYSSSQDPPEQSFPMCTLRSFPNKIE 621
           6679*********9899999999************************************************************************** PP
   S: 185  htiewa............vlfnklleeeag.eeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtks 268
           hti wa            + +n +l++    e++ ++  ++++++e++   ++ l++ + ++fe+++ + ++ f+k ++n i+qll++f++d v++ 
   Q: 622  HTIAWArelfdssfirpaETVNLYLSQPGYlESTLKQGGNEKQTLETL---RDYLTKDRARSFEDCVIWGRNLFEKNYNNAIRQLLHNFPKDSVSST 715
           ****************99888877765544044444444444444444...4558889999************************************ PP
   S: 269  kspfwv.......................................................sfcsnaealqvpekvekdeevvkasap......... 301
           ++pfw+                                                       +f++           +k ++ +k+++p         
   Q: 716  GTPFWSgpkrapdpltfdpedashfgfvvaaaslhafnyninvkdktkqdfldvlsnmiveEFEPDP--------DVKIQADDKEPDPnagasafdd 804
           ********************************99999888887777777666666666666444433........3333333333333334444445 PP
   S: 302  ...lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..k 391
              l+  ++ l   +   g k + ++fekddd   ++d++taa+nlra +++ie+ +d++++k iag+iipaiatt+a v Gl+++E++K+++g  +
   Q: 805  tneLEQIIKELPAPKDMAGFKLTPVEFEKDDDTnhHIDFITAASNLRAANYKIEQ-ADRHKTKFIAGKIIPAIATTTALVTGLVVLELYKIIDGkdD 900
           667*****************************999********************.**************************************777 PP
   S: 392  feplknfflfdae 404
            e++kn f+++a+
   Q: 901  IEQYKNGFVNLAL 913
           889*****99875 PP

Organism

Magnaporthe poae

Protein Sequence
(Fasta)

MADQRLPEVD LVTRMQVDDS VVNVVGGGEI DESLYSRQLY VLGHEAMRRM GASNVLIAGL 60
KGIGVEIAKN IALAGVKSLS LHDPAPVAIA DLSSQFFLRP EDVGKPRDQV TAPRVAELNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCTCCCGG AGGGGTAGAG CTTGGAACCT GGTGGTGGAT GACAACATAT GCGTCCCACT 60
CCTCCGTCAT TACAAACAAT CCACCTGCCA ACCTGCGCTG CCGACACTCA CCTTGCTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	45.41	0.00e+00	807.00
IUUC-Aml-001311	Ailuropoda melanoleuca	54.05	0.00e+00	1082.00
IUUC-Atr-002684	Amborella trichopoda	45.06	0.00e+00	855.00
IUUC-Apl-004158	Anas platyrhynchos	43.07	0.00e+00	691.00
IUUC-Aca-004620	Anolis carolinensis	54.48	0.00e+00	1086.00
IUUC-Aly-005418	Arabidopsis lyrata	45.70	0.00e+00	866.00
IUUC-Ath-006891	Arabidopsis thaliana	45.11	0.00e+00	857.00
IUUC-Ago-007873	Ashbya gossypii	59.47	0.00e+00	1165.00
IUUC-Acl-008181	Aspergillus clavatus	68.61	0.00e+00	1458.00
IUUC-Afl-008455	Aspergillus flavus	68.58	0.00e+00	1405.00
IUUC-Afu-009065	Aspergillus fumigatus	69.23	0.00e+00	1487.00
IUUC-Ani-009371	Aspergillus nidulans	69.13	0.00e+00	1441.00
IUUC-Ang-009737	Aspergillus niger	69.00	0.00e+00	1465.00
IUUC-Aor-010007	Aspergillus oryzae	68.58	0.00e+00	1407.00
IUUC-Ate-010466	Aspergillus terreus	68.42	0.00e+00	1481.00
IUUC-Ame-010933	Astyanax mexicanus	54.28	0.00e+00	1029.00
IUUC-Bgr-012281	Blumeria graminis	70.41	0.00e+00	1511.00
IUUC-Bta-012767	Bos taurus	54.18	0.00e+00	1088.00
IUUC-Bci-013721	Botrytis cinerea	74.25	0.00e+00	1527.00
IUUC-Bdi-014009	Brachypodium distachyon	44.65	0.00e+00	852.00
IUUC-Bol-015665	Brassica oleracea	45.74	0.00e+00	858.00
IUUC-Bra-017685	Brassica rapa	45.80	0.00e+00	867.00
IUUC-Cel-018260	Caenorhabditis elegans	45.33	0.00e+00	817.00
IUUC-Cja-019152	Callithrix jacchus	54.53	0.00e+00	1085.00
IUUC-Cfa-020622	Canis familiaris	53.37	0.00e+00	1032.00
IUUC-Cpo-022526	Cavia porcellus	54.34	0.00e+00	1066.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	45.10	0.00e+00	788.00
IUUC-Csa-023780	Chlorocebus sabaeus	54.15	0.00e+00	1074.00
IUUC-Cho-024682	Choloepus hoffmanni	40.62	6.00e-97	347.00
IUUC-Cin-025790	Ciona intestinalis	50.62	0.00e+00	1039.00
IUUC-Csv-026084	Ciona savignyi	50.52	0.00e+00	1026.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	76.65	0.00e+00	1672.00
IUUC-Cne-026960	Cryptococcus neoformans	59.75	0.00e+00	1199.00
IUUC-Cme-027290	Cyanidioschyzon merolae	42.92	0.00e+00	785.00
IUUC-Dre-028149	Danio rerio	54.42	0.00e+00	1067.00
IUUC-Dno-028884	Dasypus novemcinctus	54.39	0.00e+00	1085.00
IUUC-Dor-030229	Dipodomys ordii	52.00	0.00e+00	1011.00
IUUC-Dse-031524	Dothistroma septosporum	69.22	0.00e+00	1427.00
IUUC-Dme-032045	Drosophila melanogaster	51.03	0.00e+00	998.00
IUUC-Ete-033124	Echinops telfairi	43.49	4.00e-151	526.00
IUUC-Eca-033330	Equus caballus	54.15	0.00e+00	1081.00
IUUC-Eeu-035323	Erinaceus europaeus	40.46	9.00e-152	529.00
IUUC-Fca-036255	Felis catus	54.54	0.00e+00	1082.00
IUUC-Fal-036848	Ficedula albicollis	43.36	0.00e+00	707.00
IUUC-Fox-038007	Fusarium oxysporum	73.32	0.00e+00	834.00
IUUC-Fso-038339	Fusarium solani	75.70	0.00e+00	1583.00
IUUC-Gmo-039338	Gadus morhua	52.38	0.00e+00	1016.00
IUUC-Ggr-039823	Gaeumannomyces graminis	96.05	0.00e+00	2077.00
IUUC-Gga-040747	Gallus gallus	42.74	0.00e+00	682.00
IUUC-Gac-041773	Gasterosteus aculeatus	52.14	0.00e+00	1018.00
IUUC-Gma-043198	Glycine max	45.13	0.00e+00	859.00
IUUC-Ggo-045336	Gorilla gorilla	54.24	0.00e+00	1062.00
IUUC-Hsa-045982	Homo sapiens	54.24	0.00e+00	1062.00
IUUC-Hvu-047418	Hordeum vulgare	45.60	0.00e+00	842.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	54.63	0.00e+00	1087.00
IUUC-Kpa-049112	Komagataella pastoris	59.86	0.00e+00	1158.00
IUUC-Lch-050371	Latimeria chalumnae	54.87	0.00e+00	1088.00
IUUC-Lpe-051299	Leersia perrieri	44.85	0.00e+00	871.00
IUUC-Loc-052936	Lepisosteus oculatus	55.05	0.00e+00	1083.00
IUUC-Lma-053315	Leptosphaeria maculans	69.45	0.00e+00	1509.00
IUUC-Laf-053948	Loxodonta africana	54.58	0.00e+00	1056.00
IUUC-Mcc-055843	Macaca mulatta	54.44	0.00e+00	1085.00
IUUC-Meu-056258	Macropus eugenii	54.09	0.00e+00	1067.00
IUUC-Mor-057269	Magnaporthe oryzae	88.63	0.00e+00	1910.00
IUUC-Mtr-058572	Medicago truncatula	45.56	0.00e+00	849.00
IUUC-Mla-059176	Melampsora laricipopulina	58.00	0.00e+00	1140.00
IUUC-Mga-059721	Meleagris gallopavo	42.65	0.00e+00	667.00
IUUC-Mvi-060437	Microbotryum violaceum	57.14	0.00e+00	1159.00
IUUC-Mmr-061405	Microcebus murinus	53.20	0.00e+00	1037.00
IUUC-Mdo-062032	Monodelphis domestica	52.80	0.00e+00	1031.00
IUUC-Mmu-063280	Mus musculus	54.15	0.00e+00	1078.00
IUUC-Mac-065505	Musa acuminata	45.95	0.00e+00	867.00
IUUC-Mpu-066409	Mustela putorius furo	54.24	0.00e+00	1086.00
IUUC-Mlu-067217	Myotis lucifugus	53.95	0.00e+00	1069.00
IUUC-Nfi-068407	Neosartorya fischeri	69.62	0.00e+00	1473.00
IUUC-Ncr-068698	Neurospora crassa	79.36	0.00e+00	1711.00
IUUC-Nle-070072	Nomascus leucogenys	51.61	0.00e+00	978.00
IUUC-Opr-070715	Ochotona princeps	37.54	5.00e-177	613.00
IUUC-Ont-071671	Oreochromis niloticus	54.96	0.00e+00	1064.00
IUUC-Oan-073268	Ornithorhynchus anatinus	42.43	0.00e+00	653.00
IUUC-Ocu-074544	Oryctolagus cuniculus	54.54	0.00e+00	1091.00
IUUC-Oba-075120	Oryza barthii	43.93	0.00e+00	836.00
IUUC-Obr-076244	Oryza brachyantha	45.29	0.00e+00	857.00
IUUC-Ogl-077887	Oryza glaberrima	44.23	0.00e+00	837.00
IUUC-Ogu-078793	Oryza glumaepatula	45.32	0.00e+00	852.00
IUUC-Oin-079710	Oryza indica	45.32	0.00e+00	849.00
IUUC-Olo-081089	Oryza longistaminata	45.09	0.00e+00	860.00
IUUC-Ome-081942	Oryza meridionalis	43.78	0.00e+00	838.00
IUUC-Oni-082365	Oryza nivara	44.12	0.00e+00	840.00
IUUC-Opu-083977	Oryza punctata	44.30	0.00e+00	840.00
IUUC-Oru-084469	Oryza rufipogon	44.90	0.00e+00	856.00
IUUC-Osa-085949	Oryza sativa	44.22	0.00e+00	845.00
IUUC-Ola-087002	Oryzias latipes	55.00	0.00e+00	1071.00
IUUC-Olu-087687	Ostreococcus lucimarinus	43.00	0.00e+00	757.00
IUUC-Oga-088594	Otolemur garnettii	54.83	0.00e+00	1065.00
IUUC-Oar-090068	Ovis aries	54.48	0.00e+00	1087.00
IUUC-Ptr-090609	Pan troglodytes	42.83	0.00e+00	691.00
IUUC-Pan-092114	Papio anubis	54.34	0.00e+00	1082.00
IUUC-Psi-093489	Pelodiscus sinensis	42.64	0.00e+00	708.00
IUUC-Pma-094214	Petromyzon marinus	47.34	3.00e-40	155.00
IUUC-Pno-095154	Phaeosphaeria nodorum	68.64	0.00e+00	1496.00
IUUC-Ppa-095416	Physcomitrella patens	47.12	0.00e+00	861.00
IUUC-Pfo-097184	Poecilia formosa	54.58	0.00e+00	1065.00
IUUC-Pab-097861	Pongo abelii	54.24	0.00e+00	1052.00
IUUC-Pop-098934	Populus trichocarpa	45.61	0.00e+00	861.00
IUUC-Pca-100347	Procavia capensis	52.71	0.00e+00	902.00
IUUC-Ppe-102012	Prunus persica	44.74	0.00e+00	870.00
IUUC-Pva-102584	Pteropus vampyrus	54.63	0.00e+00	1117.00
IUUC-Pgr-103336	Puccinia graminis	56.02	0.00e+00	1101.00
IUUC-Ptt-103939	Puccinia triticina	56.11	0.00e+00	1096.00
IUUC-Pte-104200	Pyrenophora teres	68.99	0.00e+00	1511.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	68.74	0.00e+00	1501.00
IUUC-Rno-105462	Rattus norvegicus	54.34	0.00e+00	1076.00
IUUC-Sce-106245	Saccharomyces cerevisiae	59.32	0.00e+00	1202.00
IUUC-Sha-107142	Sarcophilus harrisii	53.46	0.00e+00	1060.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	57.46	0.00e+00	1211.00
IUUC-Spo-108034	Schizosaccharomyces pombe	58.09	0.00e+00	1177.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	73.77	0.00e+00	1540.00
IUUC-Smo-108912	Selaginella moellendorffii	46.73	0.00e+00	853.00
IUUC-Sit-110281	Setaria italica	45.06	0.00e+00	858.00
IUUC-Sly-110914	Solanum lycopersicum	45.30	0.00e+00	892.00
IUUC-Stu-112109	Solanum tuberosum	44.92	0.00e+00	890.00
IUUC-Sar-113737	Sorex araneus	54.05	0.00e+00	1076.00
IUUC-Sbi-114774	Sorghum bicolor	45.39	0.00e+00	882.00
IUUC-Sre-115148	Sporisorium reilianum	57.93	0.00e+00	1138.00
IUUC-Ssc-115777	Sus scrofa	54.39	0.00e+00	1085.00
IUUC-Tgu-116565	Taeniopygia guttata	43.06	0.00e+00	702.00
IUUC-Tru-118742	Takifugu rubripes	55.07	0.00e+00	1037.00
IUUC-Tsy-119436	Tarsius syrichta	37.51	6.00e-162	563.00
IUUC-Tni-120401	Tetraodon nigroviridis	54.97	0.00e+00	1038.00
IUUC-Tca-121672	Theobroma cacao	44.93	0.00e+00	862.00
IUUC-Tre-122009	Trichoderma reesei	74.73	0.00e+00	1556.00
IUUC-Tvi-122259	Trichoderma virens	75.63	0.00e+00	1566.00
IUUC-Tae-125676	Triticum aestivum	44.93	0.00e+00	867.00
IUUC-Tur-126189	Triticum urartu	45.31	0.00e+00	808.00
IUUC-Tme-127055	Tuber melanosporum	61.94	0.00e+00	1272.00
IUUC-Tbe-127587	Tupaia belangeri	44.03	2.00e-160	558.00
IUUC-Ttr-128331	Tursiops truncatus	54.34	0.00e+00	1070.00
IUUC-Uma-129387	Ustilago maydis	57.57	0.00e+00	1139.00
IUUC-Vda-129977	Verticillium dahliae	77.07	0.00e+00	1576.00
IUUC-Vpa-130716	Vicugna pacos	41.10	0.00e+00	673.00
IUUC-Vvi-130857	Vitis vinifera	45.87	0.00e+00	875.00
IUUC-Xtr-132947	Xenopus tropicalis	38.65	0.00e+00	647.00
IUUC-Xma-133805	Xiphophorus maculatus	54.58	0.00e+00	1050.00
IUUC-Yli-134547	Yarrowia lipolytica	59.14	0.00e+00	1223.00
IUUC-Zma-134970	Zea mays	44.71	0.00e+00	872.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence