iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000012638.5	ENSRNOT00000017603.5	ENSRNOP00000017603.3
ENSRNOG00000012638.5	ENSRNOT00000085562.1	ENSRNOP00000069601.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-46	154.1	192	222
UBD/Beta-Prp	1.90e-61	208.3	13	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH++ v+++af ++  +l+s+sdD t+++W+
   Q: 192  GHESTVWSIAFdPSgQRLASCSDDRTVRIWR 222
           8***********6669**************8 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrsl.sgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtl 90
           +h++s++  +++ p ++lla+ + d++i++w ++  +    + l +gh+ +v+ v +sp g++l+++s D+t ++w  + ++++cv tl
   Q: 13   AHPDSRCWFLAWNPTGTLLASCGGDRKIRIWGTEGDSWicKSVLsEGHQRTVRKVAWSPCGNYLASASFDATTCIWkkNQDDFECVTTL 101
           688999999999*********************9877654566689******************************99999******** PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..ktgkllrtl 175
           +ghe++v s+++ psg+ l++ s+d+ + vw+++++ ++e   +l+ h++ v +vv+hp++ ll+s+s+D tv+l++       +  tl
   Q: 102  EGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECvsVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYQEegDDWVCCATL 190
           *********************************9987776566*********************************9833445699*** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklw 207
           +g h++ v s++fd++g++l+s+s+d+tv++w
   Q: 191  EG-HESTVWSIAFDPSGQRLASCSDDRTVRIW 221
           *9.***************************** PP

Organism

Rattus norvegicus

Functional Description
(View)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

Protein Sequence
(Fasta)

MKDALVLQSR VPAHPDSRCW FLAWNPTGTL LASCGGDRKI RIWGTEGDSW ICKSVLSEGH 60
QRTVRKVAWS PCGNYLASAS FDATTCIWKK NQDDFECVTT LEGHENEVKS VAWAPSGNLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGAGCAAT GCAATGGGCG ACTGGCCCGG AGCTGTCAGG GCCGGCACCA GAGACTGCGG 60
GGTGGGACCC AGGGCTGAGC ACGGACCAAA GGACTGCGGG AATTCGGGGG GCGGGGACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0071817--C:MMXD complex
GO:0007059--P:chromosome segregation
GO:0016226--P:iron-sulfur cluster assembly

KEGG

rno:29231

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	42.66	2.00e-67	250.00
IUUC-Aml-001317	Ailuropoda melanoleuca	94.40	2.00e-179	620.00
IUUC-Atr-003029	Amborella trichopoda	52.35	7.00e-94	337.00
IUUC-Apl-004042	Anas platyrhynchos	78.03	3.00e-56	209.00
IUUC-Aly-006458	Arabidopsis lyrata	48.70	3.00e-85	308.00
IUUC-Ath-006671	Arabidopsis thaliana	48.70	5.00e-85	307.00
IUUC-Ago-007820	Ashbya gossypii	41.64	9.00e-61	227.00
IUUC-Acl-008042	Aspergillus clavatus	31.86	5.00e-50	191.00
IUUC-Afl-008639	Aspergillus flavus	32.86	3.00e-52	199.00
IUUC-Afu-008899	Aspergillus fumigatus	36.08	6.00e-50	191.00
IUUC-Ani-009453	Aspergillus nidulans	32.93	1.00e-50	194.00
IUUC-Ang-009758	Aspergillus niger	35.31	1.00e-51	197.00
IUUC-Aor-010212	Aspergillus oryzae	32.86	3.00e-52	199.00
IUUC-Ate-010314	Aspergillus terreus	33.09	4.00e-53	201.00
IUUC-Ame-010676	Astyanax mexicanus	76.88	8.00e-156	542.00
IUUC-Bgr-012095	Blumeria graminis	29.88	5.00e-37	148.00
IUUC-Bta-012884	Bos taurus	92.04	4.00e-174	603.00
IUUC-Bci-013622	Botrytis cinerea	31.99	7.00e-38	151.00
IUUC-Bdi-014614	Brachypodium distachyon	49.11	4.00e-86	311.00
IUUC-Bol-016439	Brassica oleracea	47.93	3.00e-83	301.00
IUUC-Bra-016830	Brassica rapa	47.18	8.00e-82	296.00
IUUC-Cel-018709	Caenorhabditis elegans	41.54	8.00e-65	240.00
IUUC-Cja-019822	Callithrix jacchus	94.10	1.00e-178	618.00
IUUC-Cfa-020823	Canis familiaris	94.40	2.00e-179	621.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	48.66	4.00e-81	295.00
IUUC-Csa-023754	Chlorocebus sabaeus	94.40	5.00e-180	623.00
IUUC-Cin-025395	Ciona intestinalis	59.49	4.00e-114	404.00
IUUC-Csv-025943	Ciona savignyi	55.86	7.00e-111	393.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	31.40	2.00e-37	150.00
IUUC-Cne-026939	Cryptococcus neoformans	31.99	3.00e-47	182.00
IUUC-Cme-027239	Cyanidioschyzon merolae	41.35	6.00e-45	175.00
IUUC-Dre-028172	Danio rerio	76.35	3.00e-155	541.00
IUUC-Dno-029472	Dasypus novemcinctus	93.86	3.00e-150	523.00
IUUC-Dor-031134	Dipodomys ordii	83.78	2.00e-151	528.00
IUUC-Dse-031535	Dothistroma septosporum	30.33	2.00e-47	182.00
IUUC-Dme-032020	Drosophila melanogaster	59.70	3.00e-118	417.00
IUUC-Eca-033700	Equus caballus	94.10	9.00e-179	619.00
IUUC-Eeu-035010	Erinaceus europaeus	91.15	4.00e-171	593.00
IUUC-Fca-036309	Felis catus	85.59	4.00e-167	580.00
IUUC-Fal-037243	Ficedula albicollis	74.42	1.00e-85	309.00
IUUC-Fox-038058	Fusarium oxysporum	32.66	8.00e-45	175.00
IUUC-Fso-038459	Fusarium solani	33.51	9.00e-41	160.00
IUUC-Gmo-039375	Gadus morhua	75.52	6.00e-140	489.00
IUUC-Ggr-040002	Gaeumannomyces graminis	35.75	2.00e-41	163.00
IUUC-Gga-040294	Gallus gallus	82.77	1.00e-127	449.00
IUUC-Gac-042499	Gasterosteus aculeatus	74.93	7.00e-138	483.00
IUUC-Gma-043543	Glycine max	49.55	4.00e-88	318.00
IUUC-Ggo-045181	Gorilla gorilla	94.40	5.00e-180	623.00
IUUC-Hsa-046528	Homo sapiens	94.40	5.00e-180	623.00
IUUC-Hvu-047341	Hordeum vulgare	57.45	5.00e-56	210.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	94.69	4.00e-180	623.00
IUUC-Kpa-049353	Komagataella pastoris	36.52	2.00e-55	209.00
IUUC-Lch-049763	Latimeria chalumnae	81.44	9.00e-162	562.00
IUUC-Lpe-051500	Leersia perrieri	44.39	4.00e-81	295.00
IUUC-Loc-052021	Lepisosteus oculatus	79.53	2.00e-153	534.00
IUUC-Lma-053331	Leptosphaeria maculans	35.00	2.00e-55	210.00
IUUC-Laf-054558	Loxodonta africana	92.04	3.00e-175	607.00
IUUC-Mcc-055374	Macaca mulatta	94.10	3.00e-179	620.00
IUUC-Meu-056042	Macropus eugenii	75.78	4.00e-110	390.00
IUUC-Mor-057187	Magnaporthe oryzae	34.39	2.00e-40	159.00
IUUC-Mtr-058072	Medicago truncatula	49.26	6.00e-87	313.00
IUUC-Mla-059108	Melampsora laricipopulina	31.82	4.00e-52	198.00
IUUC-Mga-059370	Meleagris gallopavo	64.04	6.00e-100	357.00
IUUC-Mvi-060495	Microbotryum violaceum	37.81	8.00e-57	214.00
IUUC-Mmr-060902	Microcebus murinus	95.58	0.00e+00	628.00
IUUC-Mdo-062510	Monodelphis domestica	90.27	6.00e-166	576.00
IUUC-Mmu-063575	Mus musculus	98.53	0.00e+00	646.00
IUUC-Mac-065322	Musa acuminata	51.04	3.00e-90	325.00
IUUC-Mpu-065925	Mustela putorius furo	93.51	7.00e-178	615.00
IUUC-Mlu-067755	Myotis lucifugus	93.51	2.00e-178	617.00
IUUC-Nfi-068327	Neosartorya fischeri	32.35	1.00e-49	190.00
IUUC-Ncr-068845	Neurospora crassa	33.23	4.00e-33	135.00
IUUC-Nle-069406	Nomascus leucogenys	92.92	8.00e-175	605.00
IUUC-Opr-070416	Ochotona princeps	75.22	4.00e-132	464.00
IUUC-Ont-071936	Oreochromis niloticus	76.42	6.00e-142	496.00
IUUC-Oan-073452	Ornithorhynchus anatinus	90.30	2.00e-74	271.00
IUUC-Ocu-074791	Oryctolagus cuniculus	93.81	1.00e-178	618.00
IUUC-Oba-075636	Oryza barthii	49.12	1.00e-88	319.00
IUUC-Obr-076742	Oryza brachyantha	48.44	3.00e-77	281.00
IUUC-Ogl-077766	Oryza glaberrima	49.12	1.00e-88	319.00
IUUC-Ogu-079039	Oryza glumaepatula	49.12	5.00e-89	321.00
IUUC-Oin-079315	Oryza indica	49.15	4.00e-78	285.00
IUUC-Olo-080669	Oryza longistaminata	43.67	7.00e-81	293.00
IUUC-Ome-081490	Oryza meridionalis	49.12	8.00e-89	320.00
IUUC-Oni-082572	Oryza nivara	49.12	1.00e-88	319.00
IUUC-Opu-083732	Oryza punctata	49.26	9.00e-89	320.00
IUUC-Oru-084763	Oryza rufipogon	49.12	1.00e-88	319.00
IUUC-Osa-085372	Oryza sativa	49.12	1.00e-88	319.00
IUUC-Ola-087379	Oryzias latipes	74.12	5.00e-139	486.00
IUUC-Olu-087801	Ostreococcus lucimarinus	35.03	1.00e-44	173.00
IUUC-Oga-089076	Otolemur garnettii	94.69	6.00e-180	622.00
IUUC-Oar-090022	Ovis aries	91.99	3.00e-172	597.00
IUUC-Ptr-090809	Pan troglodytes	94.40	5.00e-180	623.00
IUUC-Pan-091685	Papio anubis	94.40	0.00e+00	630.00
IUUC-Psi-093046	Pelodiscus sinensis	85.71	1.00e-163	569.00
IUUC-Pma-094181	Petromyzon marinus	64.01	5.00e-131	460.00
IUUC-Pno-094882	Phaeosphaeria nodorum	34.53	4.00e-56	211.00
IUUC-Ppa-095172	Physcomitrella patens	47.97	2.00e-85	308.00
IUUC-Pfo-096396	Poecilia formosa	72.84	2.00e-138	484.00
IUUC-Pab-098427	Pongo abelii	94.40	2.00e-178	618.00
IUUC-Pop-100016	Populus trichocarpa	52.23	3.00e-91	328.00
IUUC-Pca-101048	Procavia capensis	93.22	3.00e-176	610.00
IUUC-Ppe-102050	Prunus persica	48.39	8.00e-87	313.00
IUUC-Pva-103117	Pteropus vampyrus	93.51	2.00e-177	614.00
IUUC-Pgr-103307	Puccinia graminis	34.35	5.00e-57	215.00
IUUC-Ptt-103938	Puccinia triticina	38.06	1.00e-48	186.00
IUUC-Pte-104315	Pyrenophora teres	33.83	4.00e-56	212.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	33.83	5.00e-56	211.00
IUUC-Sce-106297	Saccharomyces cerevisiae	43.08	1.00e-64	239.00
IUUC-Sha-106981	Sarcophilus harrisii	90.10	4.00e-139	487.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	39.18	5.00e-56	212.00
IUUC-Spo-108214	Schizosaccharomyces pombe	40.66	4.00e-57	216.00
IUUC-Smo-109034	Selaginella moellendorffii	46.26	8.00e-83	300.00
IUUC-Sit-110663	Setaria italica	50.74	3.00e-90	325.00
IUUC-Sly-110898	Solanum lycopersicum	47.95	1.00e-82	299.00
IUUC-Stu-112647	Solanum tuberosum	51.88	5.00e-70	257.00
IUUC-Sbi-114288	Sorghum bicolor	47.94	3.00e-85	308.00
IUUC-Sre-115065	Sporisorium reilianum	43.46	3.00e-74	272.00
IUUC-Ssc-115960	Sus scrofa	87.54	9.00e-176	608.00
IUUC-Tru-118382	Takifugu rubripes	72.54	5.00e-148	516.00
IUUC-Tsy-119585	Tarsius syrichta	85.25	1.00e-157	548.00
IUUC-Tni-120133	Tetraodon nigroviridis	75.00	1.00e-143	502.00
IUUC-Tca-121167	Theobroma cacao	49.55	4.00e-81	294.00
IUUC-Tre-122119	Trichoderma reesei	29.10	6.00e-40	158.00
IUUC-Tae-125748	Triticum aestivum	48.53	6.00e-82	297.00
IUUC-Tur-126682	Triticum urartu	48.89	7.00e-68	250.00
IUUC-Tme-127095	Tuber melanosporum	35.94	7.00e-62	231.00
IUUC-Tbe-128004	Tupaia belangeri	94.99	0.00e+00	628.00
IUUC-Ttr-129284	Tursiops truncatus	89.47	9.00e-168	582.00
IUUC-Uma-129527	Ustilago maydis	43.32	2.00e-74	272.00
IUUC-Vda-129854	Verticillium dahliae	32.00	2.00e-39	156.00
IUUC-Vpa-130681	Vicugna pacos	97.41	7.00e-50	190.00
IUUC-Vvi-131004	Vitis vinifera	54.38	1.00e-88	320.00
IUUC-Xtr-131928	Xenopus tropicalis	81.25	8.00e-153	532.00
IUUC-Xma-134290	Xiphophorus maculatus	71.94	8.00e-135	473.00
IUUC-Yli-134364	Yarrowia lipolytica	44.19	2.00e-67	249.00
IUUC-Zma-135658	Zea mays	49.70	4.00e-87	314.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence