iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069579

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01097742

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000013472.2	ENSNLET00000017151.2	ENSNLEP00000016316.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-33	112.5	227	265
UBD/Beta-Prp	7.80e-54	182.8	203	389

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+d+v++++f  d  l+vs+s+Dg +++WD+ +g +lk+
   Q: 227  HSDPVSAVHFnRDgSLIVSSSYDGLCRIWDTASGQCLKT 265
           ***********7779*********************986 PP

UBD/Beta-Prp

   S: 111  sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgs 199
           sG  d+ +r+wd++tg+cl+ tl  h++ v+ v+++ dg+l+vs+s+D+ +r+Wd ++g++l+tl  +++++v  ++f++ngk+++++ 
   Q: 203  SGEFDESVRIWDVKTGKCLK-TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAAT 290
           7889****************.********************************************999********************* PP
   S: 200  ldgtvklwdlqtgecvrtlnghtdnvksvrfs...pnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse 285
           ld+t+klwd+++g+c++t++gh++  +++ +      ++++vsgs+D+ ++iW+l++++++++lq+h + vis a+ ++++n++++++ 
   Q: 291  LDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANfsvTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTAC-HPTENIIASAAL 378
           ****************************98887899****************************************.*******99988 PP
   S: 286  ..dskvniwkl 294
             d+++++wk 
   Q: 379  enDKTIKLWKS 389
           88*******96 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MPAQEGRAGP QRARCEVSLR TAERARVTPE RLCQSAGLAG NRLPLSPGPS IRISCAASVR 60
AMATEEKKPE TEAARAQPTP SSSATQSKPT PVKPNYALKF TLAGHTKAVS SVKFSPNGEW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCATGGGTT CCTGTGTCAT GTTCTGTGTT CCCATTTTTA ATTGGAGAAT AAGGGACTGT 60
ATGTTATTCT ACCCACAGGC CTAGCTGAGG GGATAGGGAG GCCGTGCCTA CCTCCAAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005671--C:Ada2/Gcn5/Ada3 transcription activator complex
GO:0071339--C:MLL1 complex
GO:0044666--C:MLL3/4 complex
GO:0048188--C:Set1C/COMPASS complex
GO:0046972--F:histone acetyltransferase activity (H4-K16 specific)
GO:0043995--F:histone acetyltransferase activity (H4-K5 specific)
GO:0043996--F:histone acetyltransferase activity (H4-K8 specific)
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence