iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034175

UUCD1 version

UUC-EqC-00780

Ensembl Protein ID

ENSECAP00000012728.1

UniProt Accession

F7C9V2; F7C9V2_HORSE

Protein Name

Uncharacterized protein

Gene Name

UFL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014582.1	ENSECAT00000015796.1	ENSECAP00000012728.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	88.32	0.00e+00	1380.00	IUUC-Hsa-046823
ULD/UDP/UBQ/UBQ_Other	88.32	0.00e+00	1380.00	IUUC-Hsa-046823
E3 activity/Other	84.40	0.00e+00	1340.00	IUUC-Mmu-064248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MADAWEEIRR LAADFQRAQF AEATQRLSER NCIEIVNKLI AQKQLEVVHT LDGKEYITPA 60
QISKEMRDEL HVRGGRVNIV DLQQVINVDL THIENRIGDI VKSEKHVQLV LGQLIDENYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGACG CCTGGGAAGA GATTAGGCGG TTGGCGGCTG ACTTCCAGCG GGCGCAGTTC 60
GCCGAGGCCA CACAGAGGTG CCGGACCCTC CCTCTCCGTT GTGGAGTCCA GAATAGACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR018611--E3_UFM1_ligase_1

Pfam

PF09743--DUF2042

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0043005--C:neuron projection
GO:0043234--C:protein complex
GO:0071568--F:UFM1 transferase activity
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0031397--P:negative regulation of protein ubiquitination
GO:0001649--P:osteoblast differentiation
GO:0060252--P:positive regulation of glial cell proliferation
GO:1990592--P:protein K69-linked ufmylation
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032880--P:regulation of protein localization
GO:0034976--P:response to endoplasmic reticulum stress
GO:1902065--P:response to L-glutamate

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000068	Aegilops tauschii	26.87	2.00e-52	200.00
IUUC-Aml-001894	Ailuropoda melanoleuca	88.69	0.00e+00	1392.00
IUUC-Atr-003137	Amborella trichopoda	33.51	5.00e-56	211.00
IUUC-Apl-003993	Anas platyrhynchos	69.91	0.00e+00	1040.00
IUUC-Aca-004941	Anolis carolinensis	67.81	0.00e+00	839.00
IUUC-Aly-006023	Arabidopsis lyrata	25.94	5.00e-64	239.00
IUUC-Ath-007249	Arabidopsis thaliana	25.25	8.00e-65	241.00
IUUC-Ame-011084	Astyanax mexicanus	72.27	1.00e-136	479.00
IUUC-Bta-012960	Bos taurus	88.69	0.00e+00	1386.00
IUUC-Bdi-014730	Brachypodium distachyon	26.62	3.00e-64	240.00
IUUC-Bol-016306	Brassica oleracea	26.52	2.00e-63	237.00
IUUC-Bra-016735	Brassica rapa	25.86	4.00e-61	229.00
IUUC-Cel-018267	Caenorhabditis elegans	28.44	2.00e-36	147.00
IUUC-Cja-019432	Callithrix jacchus	87.80	0.00e+00	1357.00
IUUC-Cfa-020879	Canis familiaris	88.18	0.00e+00	1340.00
IUUC-Cpo-021915	Cavia porcellus	81.95	0.00e+00	1254.00
IUUC-Cre-022838	Chlamydomonas reinhardtii	42.97	2.00e-23	101.00
IUUC-Csa-023667	Chlorocebus sabaeus	88.32	0.00e+00	1376.00
IUUC-Cin-025254	Ciona intestinalis	41.09	0.00e+00	629.00
IUUC-Csv-026110	Ciona savignyi	41.06	2.00e-176	612.00
IUUC-Dre-028832	Danio rerio	68.55	4.00e-174	604.00
IUUC-Dno-029396	Dasypus novemcinctus	82.37	0.00e+00	1233.00
IUUC-Dor-030872	Dipodomys ordii	71.30	2.00e-161	563.00
IUUC-Dme-031860	Drosophila melanogaster	34.71	2.00e-114	406.00
IUUC-Ete-032382	Echinops telfairi	81.03	0.00e+00	1233.00
IUUC-Eeu-035073	Erinaceus europaeus	89.07	4.00e-159	555.00
IUUC-Fca-035655	Felis catus	85.89	0.00e+00	1327.00
IUUC-Fal-037594	Ficedula albicollis	66.72	0.00e+00	874.00
IUUC-Gmo-038897	Gadus morhua	57.46	0.00e+00	775.00
IUUC-Gga-040147	Gallus gallus	70.85	0.00e+00	1058.00
IUUC-Gac-042365	Gasterosteus aculeatus	59.15	0.00e+00	917.00
IUUC-Gma-044359	Glycine max	33.51	6.00e-43	169.00
IUUC-Ggo-045085	Gorilla gorilla	87.94	0.00e+00	1356.00
IUUC-Hsa-046823	Homo sapiens	88.32	0.00e+00	1359.00
IUUC-Hvu-047672	Hordeum vulgare	28.08	1.00e-69	257.00
IUUC-Itr-048558	Ictidomys tridecemlineatus	87.67	0.00e+00	1353.00
IUUC-Lch-050099	Latimeria chalumnae	66.33	0.00e+00	1075.00
IUUC-Lpe-051353	Leersia perrieri	27.60	3.00e-71	263.00
IUUC-Loc-052237	Lepisosteus oculatus	63.99	0.00e+00	1004.00
IUUC-Laf-053535	Loxodonta africana	83.21	0.00e+00	1274.00
IUUC-Mcc-054991	Macaca mulatta	88.19	0.00e+00	1377.00
IUUC-Meu-055924	Macropus eugenii	70.10	2.00e-93	336.00
IUUC-Mtr-058527	Medicago truncatula	26.76	3.00e-51	197.00
IUUC-Mga-059514	Meleagris gallopavo	69.64	0.00e+00	1060.00
IUUC-Mmr-061625	Microcebus murinus	88.93	0.00e+00	1390.00
IUUC-Mdo-062551	Monodelphis domestica	78.89	0.00e+00	1215.00
IUUC-Mmu-064248	Mus musculus	84.65	0.00e+00	1308.00
IUUC-Mac-065571	Musa acuminata	34.09	1.00e-57	218.00
IUUC-Mpu-065883	Mustela putorius furo	89.07	0.00e+00	1370.00
IUUC-Mlu-067468	Myotis lucifugus	86.68	0.00e+00	1351.00
IUUC-Nle-069831	Nomascus leucogenys	88.19	0.00e+00	1380.00
IUUC-Opr-071153	Ochotona princeps	63.41	0.00e+00	781.00
IUUC-Ont-072677	Oreochromis niloticus	61.88	0.00e+00	942.00
IUUC-Oan-073682	Ornithorhynchus anatinus	70.15	0.00e+00	1030.00
IUUC-Ocu-074268	Oryctolagus cuniculus	88.18	0.00e+00	1386.00
IUUC-Oba-075467	Oryza barthii	27.80	4.00e-69	256.00
IUUC-Obr-076760	Oryza brachyantha	29.37	5.00e-71	262.00
IUUC-Ogl-077088	Oryza glaberrima	28.03	3.00e-69	256.00
IUUC-Ogu-078509	Oryza glumaepatula	28.04	2.00e-70	260.00
IUUC-Oin-079276	Oryza indica	28.34	1.00e-71	264.00
IUUC-Olo-080814	Oryza longistaminata	27.89	9.00e-69	254.00
IUUC-Ome-081647	Oryza meridionalis	26.89	4.00e-67	249.00
IUUC-Oni-082954	Oryza nivara	27.68	1.00e-68	254.00
IUUC-Opu-083580	Oryza punctata	27.08	4.00e-61	229.00
IUUC-Oru-084627	Oryza rufipogon	28.34	1.00e-71	264.00
IUUC-Osa-086096	Oryza sativa	28.34	1.00e-71	264.00
IUUC-Ola-087322	Oryzias latipes	60.38	0.00e+00	934.00
IUUC-Olu-087693	Ostreococcus lucimarinus	25.98	3.00e-20	93.20
IUUC-Oga-088769	Otolemur garnettii	84.42	0.00e+00	1305.00
IUUC-Oar-090007	Ovis aries	87.58	0.00e+00	1369.00
IUUC-Ptr-090760	Pan troglodytes	87.94	0.00e+00	1354.00
IUUC-Pan-092162	Papio anubis	88.32	0.00e+00	1377.00
IUUC-Psi-093045	Pelodiscus sinensis	71.02	0.00e+00	1060.00
IUUC-Ppa-095424	Physcomitrella patens	35.53	3.00e-58	219.00
IUUC-Pfo-096108	Poecilia formosa	59.77	0.00e+00	932.00
IUUC-Pab-098057	Pongo abelii	85.30	0.00e+00	1323.00
IUUC-Pop-099790	Populus trichocarpa	26.13	3.00e-63	236.00
IUUC-Pca-100307	Procavia capensis	81.66	0.00e+00	1255.00
IUUC-Ppe-102029	Prunus persica	25.68	1.00e-62	234.00
IUUC-Pva-102386	Pteropus vampyrus	84.41	0.00e+00	858.00
IUUC-Rno-105550	Rattus norvegicus	85.41	0.00e+00	1287.00
IUUC-Sha-107442	Sarcophilus harrisii	80.03	0.00e+00	1223.00
IUUC-Spo-108126	Schizosaccharomyces pombe	28.70	1.40e-01	31.20
IUUC-Smo-109447	Selaginella moellendorffii	33.68	1.00e-55	211.00
IUUC-Sit-110568	Setaria italica	31.69	8.00e-50	192.00
IUUC-Sly-111028	Solanum lycopersicum	31.88	4.00e-51	196.00
IUUC-Stu-112317	Solanum tuberosum	31.36	4.00e-49	189.00
IUUC-Sar-113662	Sorex araneus	80.08	0.00e+00	1230.00
IUUC-Sbi-114636	Sorghum bicolor	26.70	2.00e-67	250.00
IUUC-Ssc-116423	Sus scrofa	87.81	0.00e+00	1368.00
IUUC-Tgu-116977	Taeniopygia guttata	68.01	0.00e+00	1055.00
IUUC-Tru-118314	Takifugu rubripes	57.78	0.00e+00	895.00
IUUC-Tsy-119391	Tarsius syrichta	85.41	0.00e+00	1304.00
IUUC-Tni-120594	Tetraodon nigroviridis	59.42	0.00e+00	887.00
IUUC-Tca-121351	Theobroma cacao	27.96	2.00e-65	243.00
IUUC-Tae-122849	Triticum aestivum	28.08	2.00e-68	253.00
IUUC-Tur-126308	Triticum urartu	27.61	3.00e-66	246.00
IUUC-Tbe-127999	Tupaia belangeri	86.46	0.00e+00	1238.00
IUUC-Ttr-129189	Tursiops truncatus	81.64	0.00e+00	1248.00
IUUC-Vpa-130734	Vicugna pacos	83.52	0.00e+00	1289.00
IUUC-Vvi-131695	Vitis vinifera	26.59	6.00e-61	228.00
IUUC-Xtr-132004	Xenopus tropicalis	61.20	0.00e+00	926.00
IUUC-Xma-134108	Xiphophorus maculatus	58.01	0.00e+00	807.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence