iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020588

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03013975

Gene Name

UBE2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000009745.4	ENSCAFT00000015479.4	ENSCAFP00000014322.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.60e-45	153.4	34	166

Active Site

Position(s)	Description	Evidence
114	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++el++l+ +  +gisa p+++ +l++w  +i G ++t+Ye+  +kl++efp+ YP+++P+vkflt+++hPnv+++G++Cl+ilk  
   Q: 34   RLQQELMTLMMSGDKGISAFPESD-NLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILK-- 119
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           +kWs+ ++v+++llsiqsll epn++spln++aael+k+   ++kk +
   Q: 120  DKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPT-AFKKYL 166
           ***********************************997655.488765 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MASQNRDPAA ASVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF 60
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCTCCC AGAACCGAGA CCCAGCCGCC GCCAGCGTCG CCGCCGCCCG GAAAGGAGCC 60
GAACCCAGCG GGGGCGCCGC CCGGGGCCCC GTGGGCAAGA GGTGAGGAGT ATGGAGGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0010458--P:exit from mitosis
GO:0010994--P:free ubiquitin chain polymerization
GO:0031536--P:positive regulation of exit from mitosis
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001924	Ailuropoda melanoleuca	97.79	8.00e-95	338.00
IUUC-Atr-002885	Amborella trichopoda	63.76	9.00e-53	199.00
IUUC-Aly-006086	Arabidopsis lyrata	60.39	6.00e-52	196.00
IUUC-Ath-006897	Arabidopsis thaliana	59.74	1.00e-51	195.00
IUUC-Acl-008223	Aspergillus clavatus	66.93	3.00e-39	154.00
IUUC-Afl-008675	Aspergillus flavus	61.59	4.00e-38	150.00
IUUC-Afu-008997	Aspergillus fumigatus	66.14	4.00e-38	150.00
IUUC-Ani-009470	Aspergillus nidulans	55.42	5.00e-38	150.00
IUUC-Ang-009648	Aspergillus niger	59.46	1.00e-38	152.00
IUUC-Aor-009977	Aspergillus oryzae	61.67	1.00e-31	128.00
IUUC-Ate-010318	Aspergillus terreus	60.00	3.00e-38	150.00
IUUC-Ame-011302	Astyanax mexicanus	77.65	1.00e-72	265.00
IUUC-Bta-013101	Bos taurus	99.44	7.00e-100	355.00
IUUC-Bci-013787	Botrytis cinerea	57.32	5.00e-44	170.00
IUUC-Bdi-014144	Brachypodium distachyon	69.29	5.00e-57	213.00
IUUC-Bol-015613	Brassica oleracea	60.39	1.00e-52	198.00
IUUC-Bra-017562	Brassica rapa	60.39	1.00e-52	198.00
IUUC-Cpo-021384	Cavia porcellus	98.32	3.00e-99	353.00
IUUC-Csa-023437	Chlorocebus sabaeus	97.77	6.00e-100	355.00
IUUC-Cho-024330	Choloepus hoffmanni	99.15	4.00e-68	248.00
IUUC-Cin-025365	Ciona intestinalis	56.88	2.00e-31	127.00
IUUC-Csv-025933	Ciona savignyi	60.92	1.00e-57	215.00
IUUC-Cgl-026494	Colletotrichum gloeosporioides	60.54	3.00e-44	170.00
IUUC-Cme-027266	Cyanidioschyzon merolae	51.61	1.00e-37	149.00
IUUC-Dre-027375	Danio rerio	77.65	2.00e-72	264.00
IUUC-Dno-029921	Dasypus novemcinctus	96.09	4.00e-93	333.00
IUUC-Dor-030209	Dipodomys ordii	94.97	1.00e-94	338.00
IUUC-Dse-031516	Dothistroma septosporum	54.67	5.00e-38	150.00
IUUC-Dme-031942	Drosophila melanogaster	67.13	2.00e-55	208.00
IUUC-Ete-032827	Echinops telfairi	85.71	2.00e-40	156.00
IUUC-Eca-034073	Equus caballus	99.44	2.00e-96	344.00
IUUC-Eeu-034854	Erinaceus europaeus	74.86	2.00e-67	248.00
IUUC-Fca-035666	Felis catus	99.44	2.00e-96	344.00
IUUC-Fal-037652	Ficedula albicollis	86.67	2.00e-53	199.00
IUUC-Fox-037793	Fusarium oxysporum	63.43	5.00e-43	166.00
IUUC-Fso-038151	Fusarium solani	64.18	3.00e-44	170.00
IUUC-Gmo-038894	Gadus morhua	78.48	3.00e-60	223.00
IUUC-Ggr-039730	Gaeumannomyces graminis	61.03	3.00e-35	140.00
IUUC-Gga-040537	Gallus gallus	86.76	3.00e-70	256.00
IUUC-Gac-041346	Gasterosteus aculeatus	77.86	1.00e-61	228.00
IUUC-Gma-043989	Glycine max	63.76	4.00e-54	203.00
IUUC-Ggo-045594	Gorilla gorilla	96.69	3.00e-98	350.00
IUUC-Hsa-046216	Homo sapiens	97.77	1.00e-99	354.00
IUUC-Hvu-047797	Hordeum vulgare	70.15	4.00e-54	204.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	99.44	2.00e-96	344.00
IUUC-Kpa-049294	Komagataella pastoris	62.68	1.00e-47	182.00
IUUC-Lch-049761	Latimeria chalumnae	70.39	9.00e-70	255.00
IUUC-Lpe-051089	Leersia perrieri	63.46	3.00e-55	207.00
IUUC-Loc-052297	Lepisosteus oculatus	77.65	2.00e-72	266.00
IUUC-Lma-053214	Leptosphaeria maculans	54.93	7.00e-43	166.00
IUUC-Laf-054468	Loxodonta africana	96.69	9.00e-98	348.00
IUUC-Mcc-055338	Macaca mulatta	97.77	6.00e-100	355.00
IUUC-Meu-056147	Macropus eugenii	92.74	1.00e-92	332.00
IUUC-Mor-057239	Magnaporthe oryzae	58.50	1.00e-41	162.00
IUUC-Mpo-057491	Magnaporthe poae	62.50	9.00e-44	169.00
IUUC-Mtr-057687	Medicago truncatula	67.14	1.00e-46	179.00
IUUC-Mla-058880	Melampsora laricipopulina	64.29	4.00e-50	190.00
IUUC-Mga-059929	Meleagris gallopavo	86.73	6.00e-49	184.00
IUUC-Mvi-060528	Microbotryum violaceum	58.78	1.00e-45	176.00
IUUC-Mmr-060747	Microcebus murinus	99.38	2.00e-85	307.00
IUUC-Mdo-062343	Monodelphis domestica	93.89	2.00e-93	334.00
IUUC-Mmu-063563	Mus musculus	97.77	9.00e-98	348.00
IUUC-Mac-064823	Musa acuminata	63.83	7.00e-53	199.00
IUUC-Mpu-065746	Mustela putorius furo	98.90	2.00e-95	341.00
IUUC-Mlu-067388	Myotis lucifugus	96.69	2.00e-93	334.00
IUUC-Nfi-068577	Neosartorya fischeri	63.04	8.00e-39	152.00
IUUC-Ncr-068803	Neurospora crassa	57.69	3.00e-38	150.00
IUUC-Opr-070902	Ochotona princeps	95.56	2.00e-94	337.00
IUUC-Ont-071672	Oreochromis niloticus	81.16	2.00e-64	237.00
IUUC-Oan-073728	Ornithorhynchus anatinus	83.13	2.00e-38	150.00
IUUC-Ocu-074566	Oryctolagus cuniculus	95.00	3.00e-91	327.00
IUUC-Oba-075538	Oryza barthii	67.94	8.00e-52	195.00
IUUC-Obr-076757	Oryza brachyantha	70.65	2.00e-36	142.00
IUUC-Ogu-078467	Oryza glumaepatula	66.44	6.00e-56	209.00
IUUC-Oin-079533	Oryza indica	67.18	3.00e-51	193.00
IUUC-Olo-080673	Oryza longistaminata	68.70	2.00e-52	197.00
IUUC-Ome-081483	Oryza meridionalis	67.86	3.00e-55	207.00
IUUC-Oni-082321	Oryza nivara	66.44	6.00e-56	209.00
IUUC-Opu-083245	Oryza punctata	66.43	5.00e-54	203.00
IUUC-Oru-084641	Oryza rufipogon	63.64	3.00e-54	204.00
IUUC-Osa-085992	Oryza sativa	66.44	6.00e-56	209.00
IUUC-Ola-086807	Oryzias latipes	73.03	5.00e-71	259.00
IUUC-Olu-087834	Ostreococcus lucimarinus	70.07	3.00e-55	206.00
IUUC-Oga-088699	Otolemur garnettii	96.70	2.00e-98	350.00
IUUC-Oar-089542	Ovis aries	98.90	1.00e-95	341.00
IUUC-Ptr-091069	Pan troglodytes	97.77	1.00e-99	354.00
IUUC-Pan-092533	Papio anubis	96.69	1.00e-98	351.00
IUUC-Psi-093581	Pelodiscus sinensis	69.51	3.00e-59	220.00
IUUC-Pma-094607	Petromyzon marinus	71.76	4.00e-68	250.00
IUUC-Pno-094829	Phaeosphaeria nodorum	61.42	8.00e-43	166.00
IUUC-Ppa-095861	Physcomitrella patens	67.14	2.00e-55	208.00
IUUC-Pfo-096836	Poecilia formosa	71.26	1.00e-66	244.00
IUUC-Pab-098707	Pongo abelii	97.77	1.00e-99	354.00
IUUC-Pop-099870	Populus trichocarpa	67.14	4.00e-54	203.00
IUUC-Pca-100661	Procavia capensis	97.77	3.00e-98	350.00
IUUC-Ppe-101289	Prunus persica	66.43	2.00e-53	201.00
IUUC-Pva-103235	Pteropus vampyrus	94.41	5.00e-88	316.00
IUUC-Pte-104292	Pyrenophora teres	58.52	3.00e-43	167.00
IUUC-Rno-105501	Rattus norvegicus	97.21	8.00e-98	348.00
IUUC-Sce-106133	Saccharomyces cerevisiae	62.02	7.00e-37	145.00
IUUC-Sha-107205	Sarcophilus harrisii	92.91	1.00e-76	278.00
IUUC-Sja-108009	Schizosaccharomyces japonicus	60.51	5.00e-50	189.00
IUUC-Spo-108136	Schizosaccharomyces pombe	55.81	6.00e-50	189.00
IUUC-Ssl-108394	Sclerotinia sclerotiorum	60.00	5.00e-44	170.00
IUUC-Smo-109014	Selaginella moellendorffii	65.44	3.00e-52	197.00
IUUC-Sit-110754	Setaria italica	67.14	2.00e-55	207.00
IUUC-Sly-111137	Solanum lycopersicum	66.20	1.00e-53	202.00
IUUC-Stu-112305	Solanum tuberosum	65.97	5.00e-54	203.00
IUUC-Sbi-114299	Sorghum bicolor	64.08	9.00e-52	196.00
IUUC-Ssc-115625	Sus scrofa	98.88	2.00e-96	344.00
IUUC-Tru-118289	Takifugu rubripes	76.74	8.00e-37	144.00
IUUC-Tni-120070	Tetraodon nigroviridis	72.52	3.00e-56	209.00
IUUC-Tca-121158	Theobroma cacao	67.14	5.00e-54	203.00
IUUC-Tre-121973	Trichoderma reesei	61.64	4.00e-44	170.00
IUUC-Tvi-122496	Trichoderma virens	61.64	5.00e-44	170.00
IUUC-Tae-123596	Triticum aestivum	66.44	2.00e-56	211.00
IUUC-Tur-126818	Triticum urartu	65.52	1.00e-42	164.00
IUUC-Tme-127044	Tuber melanosporum	66.42	3.00e-42	164.00
IUUC-Ttr-128548	Tursiops truncatus	77.65	1.00e-67	248.00
IUUC-Vda-129840	Verticillium dahliae	60.56	5.00e-43	166.00
IUUC-Vvi-131685	Vitis vinifera	64.43	4.00e-54	203.00
IUUC-Xtr-132953	Xenopus tropicalis	81.01	8.00e-81	292.00
IUUC-Xma-134093	Xiphophorus maculatus	71.26	2.00e-66	244.00
IUUC-Yli-134548	Yarrowia lipolytica	56.65	3.00e-49	187.00
IUUC-Zma-135182	Zea mays	66.43	1.00e-54	205.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence