iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090021

Ensembl Protein ID

ENSOARP00000019718.1

UniProt Accession

W5QAH3; W5QAH3_SHEEP

Genbank Protein ID

ENSOARP00000019718

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01025747

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000018369.1	ENSOART00000019991.1	ENSOARP00000019718.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	88.59	0.00e+00	708.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MGIMDRCKEN CISGPKTAVP LSDGPKRVPV AQQFPSQNPV SVNSGQAQRV LCPTNSSQRV 60
PSQAQKLVSI QKPVQTLKQK PPQAASAPRP VVRPPSNTQK SKQPQPPVPG NNPEKEVASK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTAGTAGGA TCTCCAGTTT GAAGTGGAGG GATCTTATGC AGGTCGCCTG GACATGAGAC 60
TCTCGAACTT GGCTGGAGTC CAGAATCACC TGAGAAACTG TCTTCTGTGG CTCTCTGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR030611--AURKA
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	63.80	3.00e-104	370.00
IUUC-Aml-001426	Ailuropoda melanoleuca	90.23	0.00e+00	723.00
IUUC-Atr-002453	Amborella trichopoda	65.16	5.00e-109	387.00
IUUC-Apl-003626	Anas platyrhynchos	72.47	1.00e-153	535.00
IUUC-Aca-004602	Anolis carolinensis	66.99	2.00e-149	522.00
IUUC-Aly-005878	Arabidopsis lyrata	63.27	1.00e-104	372.00
IUUC-Ath-007117	Arabidopsis thaliana	65.07	6.00e-106	376.00
IUUC-Acl-008199	Aspergillus clavatus	57.66	4.00e-88	318.00
IUUC-Afl-008419	Aspergillus flavus	56.93	7.00e-87	313.00
IUUC-Afu-008751	Aspergillus fumigatus	57.66	9.00e-88	317.00
IUUC-Ani-009181	Aspergillus nidulans	51.58	6.00e-91	327.00
IUUC-Ang-009787	Aspergillus niger	52.88	3.00e-88	318.00
IUUC-Aor-009980	Aspergillus oryzae	56.93	7.00e-87	313.00
IUUC-Ate-010286	Aspergillus terreus	51.53	7.00e-87	313.00
IUUC-Ame-010849	Astyanax mexicanus	60.35	4.00e-129	454.00
IUUC-Bgr-012110	Blumeria graminis	58.36	4.00e-88	318.00
IUUC-Bta-013474	Bos taurus	99.25	0.00e+00	824.00
IUUC-Bci-013756	Botrytis cinerea	59.42	6.00e-94	337.00
IUUC-Bdi-014257	Brachypodium distachyon	61.99	1.00e-105	375.00
IUUC-Bol-016310	Brassica oleracea	61.38	5.00e-104	370.00
IUUC-Bra-017438	Brassica rapa	62.86	4.00e-105	374.00
IUUC-Cel-018157	Caenorhabditis elegans	61.70	4.00e-103	367.00
IUUC-Cja-019282	Callithrix jacchus	88.34	0.00e+00	706.00
IUUC-Cfa-020162	Canis familiaris	88.69	0.00e+00	717.00
IUUC-Cpo-021764	Cavia porcellus	82.80	0.00e+00	648.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	67.16	1.00e-108	385.00
IUUC-Csa-023694	Chlorocebus sabaeus	88.59	0.00e+00	679.00
IUUC-Cho-024350	Choloepus hoffmanni	95.92	8.00e-112	395.00
IUUC-Cin-025542	Ciona intestinalis	73.00	2.00e-118	418.00
IUUC-Csv-025873	Ciona savignyi	66.55	1.00e-118	419.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	55.51	9.00e-81	293.00
IUUC-Cne-026928	Cryptococcus neoformans	60.15	2.00e-94	339.00
IUUC-Cme-027336	Cyanidioschyzon merolae	72.83	1.00e-119	423.00
IUUC-Dre-028198	Danio rerio	62.21	1.00e-131	462.00
IUUC-Dno-029928	Dasypus novemcinctus	85.79	0.00e+00	648.00
IUUC-Dor-030238	Dipodomys ordii	80.00	0.00e+00	635.00
IUUC-Dse-031266	Dothistroma septosporum	53.06	1.00e-93	336.00
IUUC-Dme-032007	Drosophila melanogaster	60.84	1.00e-99	356.00
IUUC-Ete-032911	Echinops telfairi	67.72	3.00e-133	468.00
IUUC-Eca-033749	Equus caballus	90.70	0.00e+00	719.00
IUUC-Eeu-035170	Erinaceus europaeus	85.68	0.00e+00	699.00
IUUC-Fca-035498	Felis catus	89.51	0.00e+00	717.00
IUUC-Fal-037397	Ficedula albicollis	68.69	2.00e-150	525.00
IUUC-Fox-037747	Fusarium oxysporum	51.18	1.00e-91	330.00
IUUC-Fso-038429	Fusarium solani	53.82	1.00e-90	326.00
IUUC-Gmo-039378	Gadus morhua	61.35	2.00e-128	452.00
IUUC-Ggr-039939	Gaeumannomyces graminis	58.48	1.00e-94	339.00
IUUC-Gga-040187	Gallus gallus	71.04	7.00e-153	533.00
IUUC-Gac-042223	Gasterosteus aculeatus	60.55	2.00e-133	468.00
IUUC-Gma-042870	Glycine max	63.83	3.00e-100	358.00
IUUC-Ggo-045617	Gorilla gorilla	88.34	0.00e+00	726.00
IUUC-Hsa-046968	Homo sapiens	88.59	0.00e+00	728.00
IUUC-Hvu-047072	Hordeum vulgare	54.18	9.00e-83	299.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	75.68	1.00e-170	592.00
IUUC-Kpa-049093	Komagataella pastoris	55.94	9.00e-77	280.00
IUUC-Lch-050346	Latimeria chalumnae	66.26	5.00e-146	510.00
IUUC-Lpe-051466	Leersia perrieri	66.05	4.00e-106	377.00
IUUC-Lma-053006	Leptosphaeria maculans	58.74	7.00e-90	323.00
IUUC-Laf-053422	Loxodonta africana	85.89	0.00e+00	705.00
IUUC-Mcc-055245	Macaca mulatta	87.88	0.00e+00	662.00
IUUC-Mor-056952	Magnaporthe oryzae	59.54	1.00e-90	326.00
IUUC-Mpo-057605	Magnaporthe poae	57.73	1.00e-95	342.00
IUUC-Mtr-057726	Medicago truncatula	63.73	2.00e-106	378.00
IUUC-Mla-059174	Melampsora laricipopulina	62.16	6.00e-97	347.00
IUUC-Mga-059562	Meleagris gallopavo	60.60	3.00e-118	418.00
IUUC-Mvi-060305	Microbotryum violaceum	59.93	7.00e-94	337.00
IUUC-Mmr-061588	Microcebus murinus	86.07	0.00e+00	710.00
IUUC-Mdo-061914	Monodelphis domestica	79.12	3.00e-179	620.00
IUUC-Mmu-063288	Mus musculus	81.82	0.00e+00	644.00
IUUC-Mac-064969	Musa acuminata	63.45	3.00e-107	380.00
IUUC-Mpu-066855	Mustela putorius furo	88.63	0.00e+00	710.00
IUUC-Mlu-068046	Myotis lucifugus	87.66	0.00e+00	699.00
IUUC-Nfi-068527	Neosartorya fischeri	57.66	3.00e-87	315.00
IUUC-Ncr-068678	Neurospora crassa	61.22	7.00e-93	334.00
IUUC-Nle-069848	Nomascus leucogenys	87.59	0.00e+00	719.00
IUUC-Opr-070589	Ochotona princeps	83.62	0.00e+00	645.00
IUUC-Ont-071733	Oreochromis niloticus	61.78	9.00e-126	443.00
IUUC-Oan-073399	Ornithorhynchus anatinus	85.53	2.00e-152	531.00
IUUC-Ocu-074063	Oryctolagus cuniculus	87.13	0.00e+00	715.00
IUUC-Oba-075264	Oryza barthii	62.76	4.00e-105	374.00
IUUC-Obr-076048	Oryza brachyantha	64.84	9.00e-105	372.00
IUUC-Ogl-077637	Oryza glaberrima	65.68	9.00e-105	372.00
IUUC-Ogu-078830	Oryza glumaepatula	62.76	2.00e-105	375.00
IUUC-Oin-079150	Oryza indica	62.76	2.00e-105	375.00
IUUC-Olo-080398	Oryza longistaminata	58.40	9.00e-83	300.00
IUUC-Ome-081544	Oryza meridionalis	56.13	7.00e-91	326.00
IUUC-Oni-082250	Oryza nivara	62.76	2.00e-105	375.00
IUUC-Opu-083638	Oryza punctata	64.34	1.00e-105	375.00
IUUC-Oru-084981	Oryza rufipogon	62.76	1.00e-105	375.00
IUUC-Osa-085961	Oryza sativa	62.76	1.00e-105	375.00
IUUC-Olu-087880	Ostreococcus lucimarinus	68.54	9.00e-112	396.00
IUUC-Oga-088891	Otolemur garnettii	87.37	0.00e+00	692.00
IUUC-Ptr-091458	Pan troglodytes	88.83	0.00e+00	728.00
IUUC-Pan-092546	Papio anubis	88.34	0.00e+00	675.00
IUUC-Psi-093280	Pelodiscus sinensis	75.27	1.00e-161	562.00
IUUC-Pma-094298	Petromyzon marinus	77.65	2.00e-121	428.00
IUUC-Pno-094847	Phaeosphaeria nodorum	59.19	2.00e-90	325.00
IUUC-Ppa-095855	Physcomitrella patens	62.37	2.00e-108	385.00
IUUC-Pfo-096428	Poecilia formosa	61.27	1.00e-129	456.00
IUUC-Pab-098696	Pongo abelii	87.62	0.00e+00	709.00
IUUC-Pop-099405	Populus trichocarpa	62.98	1.00e-106	379.00
IUUC-Pca-100740	Procavia capensis	80.45	0.00e+00	659.00
IUUC-Ppe-101854	Prunus persica	62.67	1.00e-107	382.00
IUUC-Pva-103212	Pteropus vampyrus	88.63	0.00e+00	701.00
IUUC-Pgr-103474	Puccinia graminis	59.36	2.00e-98	352.00
IUUC-Ptt-103933	Puccinia triticina	48.48	1.00e-61	229.00
IUUC-Pte-104089	Pyrenophora teres	50.73	4.00e-90	325.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	50.73	3.00e-90	325.00
IUUC-Rno-105057	Rattus norvegicus	83.70	0.00e+00	662.00
IUUC-Sha-107137	Sarcophilus harrisii	79.43	0.00e+00	626.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	59.56	4.00e-98	351.00
IUUC-Spo-108078	Schizosaccharomyces pombe	60.58	1.00e-101	363.00
IUUC-Smo-109288	Selaginella moellendorffii	67.04	2.00e-108	385.00
IUUC-Sit-110246	Setaria italica	64.54	1.00e-105	376.00
IUUC-Sly-111379	Solanum lycopersicum	65.12	4.00e-108	384.00
IUUC-Stu-112777	Solanum tuberosum	61.51	7.00e-107	379.00
IUUC-Sbi-114325	Sorghum bicolor	64.18	1.00e-105	375.00
IUUC-Sre-115203	Sporisorium reilianum	57.25	9.00e-81	294.00
IUUC-Ssc-115361	Sus scrofa	90.27	0.00e+00	749.00
IUUC-Tgu-116967	Taeniopygia guttata	72.53	2.00e-149	521.00
IUUC-Tru-117570	Takifugu rubripes	61.50	2.00e-134	471.00
IUUC-Tsy-119280	Tarsius syrichta	92.99	1.00e-117	416.00
IUUC-Tni-120721	Tetraodon nigroviridis	63.04	3.00e-135	474.00
IUUC-Tca-121494	Theobroma cacao	61.30	3.00e-106	377.00
IUUC-Tre-121869	Trichoderma reesei	54.13	5.00e-93	334.00
IUUC-Tvi-122510	Trichoderma virens	61.98	1.00e-91	330.00
IUUC-Tae-123071	Triticum aestivum	63.80	3.00e-104	370.00
IUUC-Tur-126240	Triticum urartu	63.80	1.00e-103	369.00
IUUC-Tme-126921	Tuber melanosporum	62.26	4.00e-96	344.00
IUUC-Tbe-127872	Tupaia belangeri	81.59	0.00e+00	628.00
IUUC-Ttr-129134	Tursiops truncatus	93.02	0.00e+00	714.00
IUUC-Uma-129412	Ustilago maydis	45.50	8.00e-79	287.00
IUUC-Vda-130003	Verticillium dahliae	58.96	5.00e-91	327.00
IUUC-Vvi-131272	Vitis vinifera	65.57	1.00e-106	379.00
IUUC-Xtr-132019	Xenopus tropicalis	67.00	9.00e-152	529.00
IUUC-Xma-134203	Xiphophorus maculatus	61.29	6.00e-136	477.00
IUUC-Yli-134503	Yarrowia lipolytica	54.62	5.00e-86	311.00
IUUC-Zma-135232	Zea mays	65.11	4.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence