iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000267

Ensembl Protein ID

EMT13397

UniProt Accession

R7W1U1; R7W1U1_AEGTA

Genbank Protein ID

EMT13397.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

KD547112

Gene Name

F775_16036

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_16036	EMT13397	EMT13397

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-25	87.1	221	251
E3 adaptor/Cullin RING/APC_C/CDC20	3.20e-117	391.9	86	396
UBD/Beta-Prp	8.20e-49	167.1	136	391

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+++v++l++  +   l+sG++D+ +++WD
   Q: 221  GHEAEVCGLRWsGSlQQLASGGNDNLVHIWD 251
           8**********744788************** PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtl.tghsarvg 100
           e+ ldap + dd+yln+ldW+sknv++vaL++++ylw+a++++ s+l  +  +   +tsvsw  eg+++avG +++ ++++D+++++ +rtl   h +rvg
   Q: 86   ERTLDAPGVVDDYYLNMLDWGSKNVVSVALENTLYLWNASDSSTSELVTVdADYGPITSVSWACEGQHIAVGLNSSDIQLWDTSSNRMLRTLrGVHESRVG 186
           689*********************************************99666778************************************555999*** PP
   S: 101  aLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.........PlkkfkehkaavkaiawsPwqk 192
           +L+Wn+ +l++G+ dg+i+ +dvr++ ++++t+++h+ evCGl+w+ + ++LasGGnDn v++wdas  +          l++f++h +avka+aw+P+q+
   Q: 187  SLAWNSSILTTGGMDGKIVNNDVRMRSHMVQTYRGHEAEVCGLRWSGSLQQLASGGNDNLVHIWDASMASsnpsvgynrWLHRFSDHLSAVKALAWCPFQS 287
           *****************************************************************987766767777666899****************** PP
   S: 193  slLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivtaagDetlrf 293
           +lLasGGG +Drcikfwnt tg +l+++dtg+qvc llw k++kel+s+ Gf ++ +tlwkyps+ k+ael+gh++Rvl+la spdg++++++a+Detlrf
   Q: 288  NLLASGGGGNDRCIKFWNTHTGLCLNSVDTGAQVCALLWNKNEKELLSACGFVQKPLTLWKYPSMVKLAELEGHTSRVLCLAQSPDGSTVASVAADETLRF 388
           ***************************************************************************************************** PP
   S: 294  wklfdkkk 301
           w++f +++
   Q: 389  WNVFGTSE 396
           ****8765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfsps 105
           +++ ++it+v ++ +++++a+g  ++ i++wd+++  +lr+l   he+ v ++ ++++  il tg+ D+ i  +d++  + +v+t++ghe++v+ l++s s
   Q: 136  DADYGPITSVSWACEGQHIAVGLNSSDIQLWDTSSNRMLRTLrGVHESRVGSLAWNSS--ILTTGGMDGKIVNNDVRmRSHMVQTYRGHEAEVCGLRWSGS 234
           567789************************************888*************..***********999**978899******************* PP
   S: 106  gdklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdg.nllvsG..slDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkel 195
            + l+sG++d+ +++wd +  +   +         +s h ++v  +++ p++ nll+sG  ++Dr++++W+  tg +l         +v  l +++n kel
   Q: 235  LQQLASGGNDNLVHIWDASMASSNPSvgynrwlhRFSDHLSAVKALAWCPFQsNLLASGggGNDRCIKFWNTHTGLCLNSVD--TGAQVCALLWNKNEKEL 333
           ******************9999998899999999************************73369******************5..589999**********9 PP
   S: 196  vs..gsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           +s  g   + ++lw + +   + +l+ght+ v++++ sp++  ++s+++D+++r+W++
   Q: 334  LSacGFVQKPLTLWKYPSMVKLAELEGHTSRVLCLAQSPDGSTVASVAADETLRFWNV 391
           9933346899**********************************************95 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MDMDMAYYLL TEPKKGKENE AVVSPAKEAY RRLLAEKLLG SRTRILAFRN KPPEPEGMLP 60
QILFETPTSS QTKPTKQRRK IPQFAERTLD APGVVDDYYL NMLDWGSKNV VSVALENTLY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACATGG ACATGGCATA TTACCTCCTT ACGGAACCTA AGAAGGGGAA GGAAAATGAA 60
GCCGTGGTAT CACCAGCTAA AGAAGCATAC AGGAGGCTTC TTGCTGAGAA ACTCCTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

ats:F775_16036

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bdi-014464	Brachypodium distachyon	89.21	0.00e+00	777.00
IUUC-Hvu-047645	Hordeum vulgare	97.84	0.00e+00	852.00
IUUC-Oin-080069	Oryza indica	80.34	0.00e+00	703.00
IUUC-Osa-085604	Oryza sativa	80.58	0.00e+00	704.00
IUUC-Tae-123640	Triticum aestivum	99.28	0.00e+00	862.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence