iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004474

Ensembl Protein ID

ENSACAP00000004649.3

UniProt Accession

G1KD51; G1KD51_ANOCA

Protein Name

Uncharacterized protein

Gene Name

PHIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004587.3	ENSACAT00000004755.3	ENSACAP00000004649.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.80e-33	110.9	189	226
UBD/Beta-Prp	1.50e-50	172.0	288	549

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 189  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 226
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsv 97
           s +k++l ++++dgti  w ++ g+l       +  +   ++v+ ++  fs  g +l+tgs+D++i+v+     +++ ++ l+ h+d+v
   Q: 288  SGSKRYLSSTGADGTICFWLWDAGTLkinprpTKFTERPRPGVQMICssFSAGGMFLATGSTDHIIRVYffGSGQPEKISELEFHTDKV 376
           67899***********999999999988888544447777777755522778888**************777779999*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            s++fs +++++vsGs+d t+r+w  + +++ +                  +++++  v++v+++  +n ++++ ++ t+++W++ tg+
   Q: 377  DSIQFSNTSSRFVSGSRDGTARIWMYKRKEWKSIlldmatrpagqnsqgvEDKITKLKVTMVAWDRHDNSVITAVNNMTLKVWNSFTGQ 465
           ************************8888888777***************888888889******************************* PP
   S: 171  llrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l++ l g h+d v  l+   fd   + l s+++dg v++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 466  LIHVLMG-HEDEVFVLEshpFDA--RVLFSAGHDGNVIVWDLAKGVKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 549
           ******9.*********444444..8899****************999988875544444566667777999999999999888887 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAGENGGGGG GRGGHSSELR AELYFLIARF LESGPCKQAA QVLIREVAEQ ELLPRRTDWT 60
GKEHPRSYQS LVKYYRHLAP DHLFQICHRL GPLLEQEIPQ SVPGVQTLLG AGRQSLLRTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGGG AAAACGGCGG CGGCGGAGGA GGAAGAGGCG GACACTCGTC GGAGCTGCGA 60
GCGGGTGAGG GAGTTGGTGG GATGGGCGAG GGAGCCAGGC TCCGGGGGGG CCGCCTAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR002469--Peptidase_S9B_N
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

acs:100559114

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	31.22	9.00e-62	233.00
IUUC-Aml-002299	Ailuropoda melanoleuca	82.18	0.00e+00	2738.00
IUUC-Atr-002600	Amborella trichopoda	31.20	2.00e-71	265.00
IUUC-Apl-003700	Anas platyrhynchos	85.48	0.00e+00	2854.00
IUUC-Aly-006406	Arabidopsis lyrata	31.58	2.00e-68	254.00
IUUC-Ath-006801	Arabidopsis thaliana	31.13	2.00e-68	254.00
IUUC-Bta-013125	Bos taurus	82.05	0.00e+00	2684.00
IUUC-Bdi-014797	Brachypodium distachyon	32.87	1.00e-53	205.00
IUUC-Bol-015737	Brassica oleracea	31.17	4.00e-72	267.00
IUUC-Bra-017961	Brassica rapa	30.98	2.00e-71	264.00
IUUC-Cja-018868	Callithrix jacchus	81.01	0.00e+00	2829.00
IUUC-Cfa-021179	Canis familiaris	81.23	0.00e+00	2706.00
IUUC-Cpo-022077	Cavia porcellus	77.80	0.00e+00	2652.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	35.14	4.00e-35	143.00
IUUC-Csa-023618	Chlorocebus sabaeus	91.61	0.00e+00	1638.00
IUUC-Cho-024794	Choloepus hoffmanni	85.10	0.00e+00	814.00
IUUC-Csv-025813	Ciona savignyi	43.97	0.00e+00	634.00
IUUC-Dre-028029	Danio rerio	78.48	0.00e+00	1321.00
IUUC-Dno-030048	Dasypus novemcinctus	82.18	0.00e+00	2749.00
IUUC-Dor-030195	Dipodomys ordii	83.57	0.00e+00	1364.00
IUUC-Dme-031752	Drosophila melanogaster	51.53	0.00e+00	667.00
IUUC-Eca-034274	Equus caballus	82.49	0.00e+00	2698.00
IUUC-Eeu-034688	Erinaceus europaeus	89.54	0.00e+00	1241.00
IUUC-Fca-035451	Felis catus	81.18	0.00e+00	2600.00
IUUC-Fal-037465	Ficedula albicollis	85.43	0.00e+00	2885.00
IUUC-Gmo-039451	Gadus morhua	65.83	0.00e+00	698.00
IUUC-Gga-040798	Gallus gallus	85.71	0.00e+00	2955.00
IUUC-Gma-043340	Glycine max	32.03	8.00e-73	269.00
IUUC-Ggo-045347	Gorilla gorilla	81.45	0.00e+00	2779.00
IUUC-Hsa-046757	Homo sapiens	91.38	0.00e+00	1608.00
IUUC-Hvu-047706	Hordeum vulgare	31.56	7.00e-37	147.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	68.90	0.00e+00	867.00
IUUC-Lch-050646	Latimeria chalumnae	76.20	0.00e+00	2651.00
IUUC-Lpe-051619	Leersia perrieri	31.55	2.00e-69	258.00
IUUC-Loc-052672	Lepisosteus oculatus	69.83	0.00e+00	2404.00
IUUC-Laf-054140	Loxodonta africana	82.29	0.00e+00	2769.00
IUUC-Mcc-055061	Macaca mulatta	90.68	0.00e+00	1620.00
IUUC-Mtr-058094	Medicago truncatula	32.75	3.00e-72	267.00
IUUC-Mdo-061903	Monodelphis domestica	84.31	0.00e+00	2915.00
IUUC-Mmu-063772	Mus musculus	82.58	0.00e+00	2821.00
IUUC-Mac-065343	Musa acuminata	31.18	1.00e-75	278.00
IUUC-Mpu-066359	Mustela putorius furo	81.72	0.00e+00	2501.00
IUUC-Nle-070094	Nomascus leucogenys	91.61	0.00e+00	1567.00
IUUC-Opr-070971	Ochotona princeps	67.76	0.00e+00	866.00
IUUC-Oan-073185	Ornithorhynchus anatinus	81.61	0.00e+00	2693.00
IUUC-Ocu-074033	Oryctolagus cuniculus	82.54	0.00e+00	2519.00
IUUC-Oba-075709	Oryza barthii	29.86	2.00e-61	231.00
IUUC-Obr-076619	Oryza brachyantha	31.22	1.00e-70	262.00
IUUC-Ogu-078641	Oryza glumaepatula	23.99	6.00e-29	123.00
IUUC-Oin-079669	Oryza indica	31.01	7.00e-52	198.00
IUUC-Olo-080755	Oryza longistaminata	31.86	6.00e-54	206.00
IUUC-Oni-082991	Oryza nivara	27.38	1.00e-38	155.00
IUUC-Opu-083233	Oryza punctata	30.79	2.00e-65	244.00
IUUC-Oru-085195	Oryza rufipogon	29.86	2.00e-61	231.00
IUUC-Oga-088578	Otolemur garnettii	81.88	0.00e+00	2702.00
IUUC-Oar-090247	Ovis aries	82.26	0.00e+00	2686.00
IUUC-Ptr-091266	Pan troglodytes	91.01	0.00e+00	1527.00
IUUC-Pan-092734	Papio anubis	91.38	0.00e+00	1634.00
IUUC-Pma-094427	Petromyzon marinus	65.95	2.00e-127	448.00
IUUC-Ppa-095793	Physcomitrella patens	29.81	1.00e-71	265.00
IUUC-Pab-098402	Pongo abelii	91.49	0.00e+00	1613.00
IUUC-Pop-099185	Populus trichocarpa	35.81	7.00e-70	259.00
IUUC-Pca-101128	Procavia capensis	74.36	0.00e+00	2440.00
IUUC-Ppe-101849	Prunus persica	31.04	9.00e-76	279.00
IUUC-Rno-106013	Rattus norvegicus	81.33	0.00e+00	2709.00
IUUC-Sha-107496	Sarcophilus harrisii	83.92	0.00e+00	2845.00
IUUC-Sit-110017	Setaria italica	31.50	2.00e-54	208.00
IUUC-Sly-111348	Solanum lycopersicum	31.36	3.00e-75	277.00
IUUC-Sar-113520	Sorex araneus	72.91	0.00e+00	1192.00
IUUC-Sbi-114195	Sorghum bicolor	30.37	7.00e-60	225.00
IUUC-Ssc-115461	Sus scrofa	79.38	0.00e+00	2674.00
IUUC-Tgu-116821	Taeniopygia guttata	84.84	0.00e+00	2900.00
IUUC-Tsy-119132	Tarsius syrichta	71.40	0.00e+00	2165.00
IUUC-Tca-121615	Theobroma cacao	30.06	6.00e-67	249.00
IUUC-Tae-125478	Triticum aestivum	30.99	5.00e-71	263.00
IUUC-Tur-126809	Triticum urartu	30.93	8.00e-69	256.00
IUUC-Tbe-127479	Tupaia belangeri	77.97	0.00e+00	1216.00
IUUC-Ttr-128427	Tursiops truncatus	78.35	0.00e+00	2631.00
IUUC-Vpa-130160	Vicugna pacos	79.48	0.00e+00	2598.00
IUUC-Vvi-131362	Vitis vinifera	31.31	2.00e-73	271.00
IUUC-Xtr-132717	Xenopus tropicalis	73.08	0.00e+00	2513.00
IUUC-Xma-133633	Xiphophorus maculatus	56.20	0.00e+00	1579.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence