iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006640

UUCD1 version

UUC-ArT-01638

Ensembl Protein ID

AT5G50430.1

UniProt Accession

Q9FK29; Q2V2Z8; Q4TYX8; UBC33_ARATH

Genbank Protein ID

BAB09462.1; AED95943.1; AED95944.1; AED95945.1; AAK55735.1; AAM98304.1; AAY44872.1

Protein Name

Probable ubiquitin-conjugating enzyme E2 33; E2 ubiquitin-conjugating enzyme 33; Ubiquitin carrier protein 33

Genbank Nucleotide ID

AB012248; CP002688; CP002688; CP002688; AF380654; AY142040; DQ027046

Gene Name

UBC33; At5g50430; MXI22.15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G50430	AT5G50430.1	AT5G50430.1
AT5G50430	AT5G50430.3	AT5G50430.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.70e-27	95.6	9	127

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.eeekWspals 97
           Rl+ke+ +l k+p+++++a+p+ + d+ ew+++++G e+tp++gg++  +i+fp++YP+kPP ++++t+  ++ + ++ k+Cls+ + ++e W+p++s
   Q: 9    RLQKEYRALCKEPVSHVVARPSPN-DILEWHYVLEGSEGTPFAGGFYYGKIKFPPEYPYKPPGITMTTP--NGRFVTQKKICLSMSDfHPESWNPMWS 103
           9**********************9.9******************************************9..9**************889********* PP
   S: 98   vesvllsiqsllaepnpesplnee 121
           v+s+l+++ s++ +  p  +  + 
   Q: 104  VSSILTGLLSFMMDNSPTTGSVNT 127
           ************775555443332 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MAEKACIKRL QKEYRALCKE PVSHVVARPS PNDILEWHYV LEGSEGTPFA GGFYYGKIKF 60
PPEYPYKPPG ITMTTPNGRF VTQKKICLSM SDFHPESWNP MWSVSSILTG LLSFMMDNSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTAAAGGAA AACCAATCTC CTTTTGATAT TTCGACACTC TCTCTTTCCT CTCTCCTTGT 60
CTCTGTACCG CGTCGAAATA TGAGAAACGA ATGATTTGAT CATCAATCAA CGAGAAACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ath:AT5G50430

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002152	Ailuropoda melanoleuca	52.33	6.00e-54	203.00
IUUC-Apl-004224	Anas platyrhynchos	54.25	2.00e-49	187.00
IUUC-Aca-005049	Anolis carolinensis	52.00	2.00e-53	201.00
IUUC-Aly-006195	Arabidopsis lyrata	93.83	1.00e-116	411.00
IUUC-Ago-007987	Ashbya gossypii	39.90	1.00e-42	165.00
IUUC-Acl-008060	Aspergillus clavatus	54.55	3.00e-43	167.00
IUUC-Afl-008561	Aspergillus flavus	35.02	1.00e-43	169.00
IUUC-Afu-008860	Aspergillus fumigatus	54.55	6.00e-43	166.00
IUUC-Ani-009333	Aspergillus nidulans	52.78	3.00e-42	164.00
IUUC-Ang-009810	Aspergillus niger	54.17	4.00e-43	167.00
IUUC-Aor-010127	Aspergillus oryzae	35.02	1.00e-43	169.00
IUUC-Ate-010362	Aspergillus terreus	53.85	1.00e-42	166.00
IUUC-Ame-010627	Astyanax mexicanus	50.58	8.00e-53	199.00
IUUC-Bgr-012069	Blumeria graminis	49.65	7.00e-39	153.00
IUUC-Bta-012472	Bos taurus	51.74	2.00e-53	201.00
IUUC-Bci-013843	Botrytis cinerea	50.35	2.00e-40	158.00
IUUC-Bdi-014467	Brachypodium distachyon	58.63	2.00e-83	301.00
IUUC-Cel-018278	Caenorhabditis elegans	48.60	8.00e-41	159.00
IUUC-Cja-018817	Callithrix jacchus	54.11	2.00e-45	175.00
IUUC-Cfa-020885	Canis familiaris	51.74	2.00e-53	201.00
IUUC-Cpo-022326	Cavia porcellus	52.33	8.00e-54	202.00
IUUC-Cre-022635	Chlamydomonas reinhardtii	62.05	1.00e-64	238.00
IUUC-Csa-023646	Chlorocebus sabaeus	52.00	4.00e-54	204.00
IUUC-Cho-025075	Choloepus hoffmanni	43.36	4.00e-31	126.00
IUUC-Cin-025389	Ciona intestinalis	51.97	3.00e-48	183.00
IUUC-Csv-026315	Ciona savignyi	43.16	7.00e-48	182.00
IUUC-Cgl-026602	Colletotrichum gloeosporioides	50.00	3.00e-40	157.00
IUUC-Cne-026808	Cryptococcus neoformans	48.57	2.00e-37	147.00
IUUC-Dre-028455	Danio rerio	52.38	8.00e-53	199.00
IUUC-Dno-029667	Dasypus novemcinctus	52.91	9.00e-54	202.00
IUUC-Dor-030747	Dipodomys ordii	48.25	1.00e-38	152.00
IUUC-Dse-031231	Dothistroma septosporum	49.65	6.00e-39	153.00
IUUC-Dme-031841	Drosophila melanogaster	49.69	4.00e-51	194.00
IUUC-Ete-032258	Echinops telfairi	45.74	5.00e-47	180.00
IUUC-Eeu-034443	Erinaceus europaeus	55.74	5.00e-39	153.00
IUUC-Fca-036167	Felis catus	48.28	8.00e-45	172.00
IUUC-Fal-037114	Ficedula albicollis	54.25	4.00e-49	187.00
IUUC-Fox-037957	Fusarium oxysporum	54.40	1.00e-39	155.00
IUUC-Fso-038277	Fusarium solani	52.45	4.00e-43	167.00
IUUC-Gmo-039501	Gadus morhua	50.60	1.00e-51	195.00
IUUC-Ggr-040010	Gaeumannomyces graminis	50.35	9.00e-41	159.00
IUUC-Gga-041257	Gallus gallus	54.25	2.00e-49	188.00
IUUC-Gac-041433	Gasterosteus aculeatus	51.16	4.00e-53	200.00
IUUC-Gma-043529	Glycine max	76.23	3.00e-107	380.00
IUUC-Ggo-044437	Gorilla gorilla	53.95	6.00e-46	176.00
IUUC-Hsa-046693	Homo sapiens	52.00	5.00e-54	203.00
IUUC-Itr-048477	Ictidomys tridecemlineatus	51.43	2.00e-53	201.00
IUUC-Kpa-049391	Komagataella pastoris	50.30	1.00e-40	159.00
IUUC-Lch-049617	Latimeria chalumnae	53.59	6.00e-49	186.00
IUUC-Loc-052157	Lepisosteus oculatus	50.58	2.00e-52	198.00
IUUC-Lma-053128	Leptosphaeria maculans	51.75	1.00e-41	162.00
IUUC-Laf-054455	Loxodonta africana	50.58	1.00e-52	198.00
IUUC-Mcc-054756	Macaca mulatta	52.00	4.00e-54	204.00
IUUC-Meu-056106	Macropus eugenii	55.74	6.00e-39	153.00
IUUC-Mor-057202	Magnaporthe oryzae	51.75	1.00e-41	162.00
IUUC-Mpo-057349	Magnaporthe poae	36.84	9.00e-41	159.00
IUUC-Mtr-058271	Medicago truncatula	73.25	2.00e-100	357.00
IUUC-Mla-058894	Melampsora laricipopulina	54.79	3.00e-45	173.00
IUUC-Mga-059493	Meleagris gallopavo	54.25	2.00e-49	188.00
IUUC-Mvi-060232	Microbotryum violaceum	52.56	4.00e-47	180.00
IUUC-Mmr-060957	Microcebus murinus	51.43	3.00e-53	201.00
IUUC-Mdo-062141	Monodelphis domestica	51.74	2.00e-53	201.00
IUUC-Mmu-063882	Mus musculus	51.74	2.00e-53	201.00
IUUC-Mac-064510	Musa acuminata	62.20	6.00e-85	306.00
IUUC-Mpu-065902	Mustela putorius furo	52.00	4.00e-54	203.00
IUUC-Mlu-068008	Myotis lucifugus	51.16	2.00e-51	194.00
IUUC-Nfi-068515	Neosartorya fischeri	54.17	4.00e-43	167.00
IUUC-Ncr-068755	Neurospora crassa	49.65	1.00e-40	159.00
IUUC-Opr-071201	Ochotona princeps	58.04	1.00e-36	145.00
IUUC-Ont-071311	Oreochromis niloticus	52.38	7.00e-53	199.00
IUUC-Oan-073310	Ornithorhynchus anatinus	52.00	2.00e-54	204.00
IUUC-Ocu-074514	Oryctolagus cuniculus	51.43	2.00e-53	201.00
IUUC-Obr-076396	Oryza brachyantha	57.72	1.00e-83	301.00
IUUC-Ola-086450	Oryzias latipes	50.58	1.00e-52	198.00
IUUC-Olu-087733	Ostreococcus lucimarinus	43.12	8.00e-32	129.00
IUUC-Oga-088054	Otolemur garnettii	47.12	1.00e-48	186.00
IUUC-Oar-089486	Ovis aries	51.74	2.00e-53	201.00
IUUC-Pan-092633	Papio anubis	52.00	4.00e-54	204.00
IUUC-Pno-095025	Phaeosphaeria nodorum	52.45	3.00e-42	164.00
IUUC-Ppa-095641	Physcomitrella patens	61.60	2.00e-88	317.00
IUUC-Pfo-096423	Poecilia formosa	53.25	3.00e-49	187.00
IUUC-Pab-097771	Pongo abelii	52.00	4.00e-54	203.00
IUUC-Pop-099714	Populus trichocarpa	72.54	6.00e-105	372.00
IUUC-Pca-100493	Procavia capensis	44.85	1.00e-30	125.00
IUUC-Pva-102224	Pteropus vampyrus	52.98	1.00e-52	199.00
IUUC-Pgr-103530	Puccinia graminis	51.27	1.00e-48	184.00
IUUC-Ptt-103776	Puccinia triticina	53.80	6.00e-48	183.00
IUUC-Pte-104166	Pyrenophora teres	52.45	9.00e-42	162.00
IUUC-Pyt-104570	Pyrenophora triticirepentis	52.45	1.00e-41	162.00
IUUC-Rno-105593	Rattus norvegicus	51.74	2.00e-53	201.00
IUUC-Sce-106212	Saccharomyces cerevisiae	43.56	5.00e-51	193.00
IUUC-Sha-106767	Sarcophilus harrisii	51.74	1.00e-53	201.00
IUUC-Sja-107907	Schizosaccharomyces japonicus	41.42	2.00e-48	184.00
IUUC-Spo-108094	Schizosaccharomyces pombe	51.25	1.00e-45	175.00
IUUC-Ssl-108556	Sclerotinia sclerotiorum	50.35	5.00e-40	157.00
IUUC-Smo-108965	Selaginella moellendorffii	61.94	4.00e-90	323.00
IUUC-Sit-110407	Setaria italica	61.79	2.00e-85	307.00
IUUC-Sly-111642	Solanum lycopersicum	74.07	2.00e-98	350.00
IUUC-Sbi-114327	Sorghum bicolor	62.90	1.00e-87	315.00
IUUC-Sre-115170	Sporisorium reilianum	54.43	1.00e-41	162.00
IUUC-Ssc-116385	Sus scrofa	51.74	2.00e-53	201.00
IUUC-Tgu-117041	Taeniopygia guttata	54.25	2.00e-49	187.00
IUUC-Tru-117697	Takifugu rubripes	52.38	5.00e-53	200.00
IUUC-Tsy-119024	Tarsius syrichta	46.51	6.00e-42	163.00
IUUC-Tni-120466	Tetraodon nigroviridis	50.88	2.00e-51	194.00
IUUC-Tca-121569	Theobroma cacao	74.60	1.00e-106	377.00
IUUC-Tre-121882	Trichoderma reesei	53.15	5.00e-43	167.00
IUUC-Tvi-122466	Trichoderma virens	51.75	3.00e-42	164.00
IUUC-Tae-124797	Triticum aestivum	59.20	1.00e-84	305.00
IUUC-Tur-126536	Triticum urartu	59.11	1.00e-83	301.00
IUUC-Tme-127051	Tuber melanosporum	50.00	3.00e-41	160.00
IUUC-Tbe-128095	Tupaia belangeri	54.47	9.00e-38	149.00
IUUC-Ttr-128466	Tursiops truncatus	51.74	2.00e-53	201.00
IUUC-Uma-129383	Ustilago maydis	54.43	9.00e-42	162.00
IUUC-Vda-130013	Verticillium dahliae	50.00	1.00e-38	152.00
IUUC-Vvi-131251	Vitis vinifera	70.37	1.00e-97	348.00
IUUC-Xtr-132408	Xenopus tropicalis	52.00	9.00e-54	202.00
IUUC-Xma-133893	Xiphophorus maculatus	53.25	2.00e-49	188.00
IUUC-Yli-134618	Yarrowia lipolytica	47.06	6.00e-42	162.00
IUUC-Zma-135216	Zea mays	62.90	5.00e-87	312.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence