iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117615

UUCD1 version

UUC-TaR-00306

Ensembl Protein ID

ENSTRUP00000015558.1

UniProt Accession

H2ST21; H2ST21_TAKRU

Protein Name

Uncharacterized protein

Gene Name

plrg1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006373.1	ENSTRUT00000015626.1	ENSTRUP00000015557.1
ENSTRUG00000006373.1	ENSTRUT00000015627.1	ENSTRUP00000015558.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-43	144.9	202	238
UBD/Beta-Prp	2.50e-60	205.4	286	493

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+++a  ++   +v+Gs D tik+WDl++g+l
   Q: 202  GHLGWVRSIAVePGnQWFVTGSADRTIKIWDLSSGKL 238
           8***********77799****************9987 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdg 138
           gh ++v+ ++++p+ ++lvt+s+D+t++vwd++t    htl+gh+++v +++ ++    +++Gshd+tir+wdl  g+    tl++h++
   Q: 286  GHLSAVYGLDLHPTIDVLVTCSRDATARVWDIRTKANAHTLTGHTNTVATVRCQAAEPQIITGSHDSTIRLWDLIAGKTRA-TLTNHKK 373
           79999***************************************************************************9.******* PP
   S: 139  vvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght..... 222
           +v++vv+hp++  ++sGs+D+ ++ W  + g+ ++ l+g h+  ++ l+++sng  lvsg+++gt+ lwd +tg   ++ ++       
   Q: 374  SVRSVVLHPQQYTFASGSADN-IKQWMFPDGNFIQNLSG-HNAIINTLAVNSNG-VLVSGADNGTIHLWDWRTGYNFQRIHAAVqpgsl 459
           ********************8.788*************9.*************8.9****************99887777777778888 PP
   S: 223  ...dnvksvrfspnderlvsgssDgsiriW...d 250
              + +    f++ + rl+++ +D++i+++   +
   Q: 460  dseSGIFACVFDSSESRLITAEADKTIKVYaedN 493
           8888888888999****************95544 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

KRSNKWGSSH DVQKHSVHTL VFRSLKRTHD MFVSDHAKSI AKDDQSHKLK LGVKLKADYS 60
AVLHMPILKE VKDRVYQQPS SVQDLSYAQT GDDPEYLITG THAYPSGPGL ALTADTKVHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGTCGTTAA GTGTGGTGGT GGTCATGTTG TTAGAGTTGT GATATATAGT TCACTGCGAC 60
GTGACTCCAA TTGGTAAAAA AATAAAAAAA TCTTTAGTAT ATTGAATTGT TCGTGGTTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0000398--P:mRNA splicing, via spliceosome
GO:0043066--P:negative regulation of apoptotic process
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	47.74	2.00e-128	452.00
IUUC-Aml-001605	Ailuropoda melanoleuca	75.24	0.00e+00	805.00
IUUC-Atr-002757	Amborella trichopoda	46.81	2.00e-127	449.00
IUUC-Apl-003198	Anas platyrhynchos	76.15	0.00e+00	831.00
IUUC-Aca-004683	Anolis carolinensis	77.97	0.00e+00	840.00
IUUC-Aly-005775	Arabidopsis lyrata	46.80	3.00e-125	442.00
IUUC-Ath-007460	Arabidopsis thaliana	60.24	2.00e-124	439.00
IUUC-Ago-007884	Ashbya gossypii	43.81	1.00e-102	366.00
IUUC-Acl-008153	Aspergillus clavatus	64.94	9.00e-130	456.00
IUUC-Afl-008384	Aspergillus flavus	65.55	3.00e-130	458.00
IUUC-Afu-009045	Aspergillus fumigatus	65.55	2.00e-130	458.00
IUUC-Ani-009229	Aspergillus nidulans	63.82	2.00e-129	456.00
IUUC-Ang-009812	Aspergillus niger	65.41	1.00e-123	436.00
IUUC-Aor-010059	Aspergillus oryzae	65.55	3.00e-130	458.00
IUUC-Ate-010351	Aspergillus terreus	65.85	5.00e-136	477.00
IUUC-Ame-011613	Astyanax mexicanus	59.42	9.00e-155	539.00
IUUC-Bgr-012042	Blumeria graminis	64.63	4.00e-135	474.00
IUUC-Bta-012406	Bos taurus	75.93	0.00e+00	807.00
IUUC-Bci-013760	Botrytis cinerea	63.32	7.00e-134	470.00
IUUC-Bdi-014776	Brachypodium distachyon	49.27	8.00e-131	460.00
IUUC-Bol-016189	Brassica oleracea	49.07	8.00e-127	447.00
IUUC-Bra-018044	Brassica rapa	48.45	9.00e-127	446.00
IUUC-Cel-018651	Caenorhabditis elegans	52.28	8.00e-151	526.00
IUUC-Cja-019974	Callithrix jacchus	75.83	0.00e+00	803.00
IUUC-Cfa-021085	Canis familiaris	75.24	0.00e+00	804.00
IUUC-Cpo-021458	Cavia porcellus	75.24	0.00e+00	805.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	61.51	1.00e-122	432.00
IUUC-Csa-023883	Chlorocebus sabaeus	75.24	0.00e+00	801.00
IUUC-Cho-024623	Choloepus hoffmanni	75.49	0.00e+00	786.00
IUUC-Cin-025190	Ciona intestinalis	61.94	0.00e+00	632.00
IUUC-Csv-026367	Ciona savignyi	60.62	1.00e-180	625.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	65.95	3.00e-139	488.00
IUUC-Cne-027069	Cryptococcus neoformans	50.10	2.00e-129	456.00
IUUC-Cme-027233	Cyanidioschyzon merolae	28.30	3.00e-32	132.00
IUUC-Dre-028260	Danio rerio	82.39	0.00e+00	878.00
IUUC-Dno-029112	Dasypus novemcinctus	75.39	0.00e+00	802.00
IUUC-Dor-031118	Dipodomys ordii	80.20	0.00e+00	692.00
IUUC-Dse-031493	Dothistroma septosporum	61.52	1.00e-125	443.00
IUUC-Dme-032138	Drosophila melanogaster	60.63	6.00e-169	587.00
IUUC-Ete-032411	Echinops telfairi	67.98	0.00e+00	659.00
IUUC-Eca-033521	Equus caballus	75.83	0.00e+00	810.00
IUUC-Eeu-035249	Erinaceus europaeus	70.34	3.00e-166	578.00
IUUC-Fca-036358	Felis catus	75.05	0.00e+00	801.00
IUUC-Fal-036933	Ficedula albicollis	76.74	0.00e+00	826.00
IUUC-Fox-037713	Fusarium oxysporum	65.64	3.00e-138	484.00
IUUC-Fso-038380	Fusarium solani	65.44	5.00e-138	484.00
IUUC-Gmo-039133	Gadus morhua	86.05	0.00e+00	895.00
IUUC-Ggr-039915	Gaeumannomyces graminis	66.67	8.00e-133	467.00
IUUC-Gga-041176	Gallus gallus	75.49	0.00e+00	820.00
IUUC-Gac-042344	Gasterosteus aculeatus	86.91	0.00e+00	929.00
IUUC-Gma-042892	Glycine max	49.38	3.00e-130	458.00
IUUC-Ggo-044478	Gorilla gorilla	75.44	0.00e+00	803.00
IUUC-Hsa-046037	Homo sapiens	75.24	0.00e+00	801.00
IUUC-Hvu-047349	Hordeum vulgare	51.36	2.00e-132	466.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	76.02	0.00e+00	810.00
IUUC-Kpa-049343	Komagataella pastoris	59.38	1.00e-119	422.00
IUUC-Lch-049830	Latimeria chalumnae	78.75	0.00e+00	853.00
IUUC-Lpe-051442	Leersia perrieri	49.06	8.00e-132	463.00
IUUC-Loc-051794	Lepisosteus oculatus	81.58	0.00e+00	833.00
IUUC-Lma-053137	Leptosphaeria maculans	54.62	2.00e-126	446.00
IUUC-Laf-053471	Loxodonta africana	75.39	0.00e+00	811.00
IUUC-Mcc-055627	Macaca mulatta	75.44	0.00e+00	804.00
IUUC-Meu-056148	Macropus eugenii	70.31	0.00e+00	740.00
IUUC-Mor-056960	Magnaporthe oryzae	66.26	3.00e-137	481.00
IUUC-Mtr-057816	Medicago truncatula	48.97	7.00e-128	450.00
IUUC-Mla-059031	Melampsora laricipopulina	65.62	2.00e-127	449.00
IUUC-Mga-059337	Meleagris gallopavo	74.95	0.00e+00	828.00
IUUC-Mvi-060217	Microbotryum violaceum	67.10	3.00e-130	458.00
IUUC-Mmr-061018	Microcebus murinus	75.39	0.00e+00	808.00
IUUC-Mdo-062863	Monodelphis domestica	76.12	0.00e+00	808.00
IUUC-Mmu-063988	Mus musculus	75.78	0.00e+00	802.00
IUUC-Mac-064459	Musa acuminata	48.37	3.00e-123	435.00
IUUC-Mpu-066559	Mustela putorius furo	75.24	0.00e+00	803.00
IUUC-Mlu-067361	Myotis lucifugus	75.83	0.00e+00	798.00
IUUC-Nfi-068492	Neosartorya fischeri	65.55	1.00e-130	459.00
IUUC-Ncr-068808	Neurospora crassa	64.60	1.00e-138	486.00
IUUC-Nle-069875	Nomascus leucogenys	75.44	0.00e+00	803.00
IUUC-Opr-070462	Ochotona princeps	87.97	2.00e-144	505.00
IUUC-Ont-071365	Oreochromis niloticus	88.09	0.00e+00	934.00
IUUC-Oan-072708	Ornithorhynchus anatinus	77.37	0.00e+00	835.00
IUUC-Ocu-074594	Oryctolagus cuniculus	74.85	0.00e+00	795.00
IUUC-Oba-075570	Oryza barthii	48.05	3.00e-131	461.00
IUUC-Obr-076366	Oryza brachyantha	65.11	2.00e-93	335.00
IUUC-Ogl-077153	Oryza glaberrima	47.84	4.00e-130	457.00
IUUC-Ogu-078540	Oryza glumaepatula	47.84	6.00e-131	460.00
IUUC-Oin-079612	Oryza indica	47.36	4.00e-129	454.00
IUUC-Olo-081077	Oryza longistaminata	47.36	4.00e-129	454.00
IUUC-Ome-081236	Oryza meridionalis	47.15	3.00e-128	451.00
IUUC-Oni-082499	Oryza nivara	47.84	6.00e-131	460.00
IUUC-Opu-083499	Oryza punctata	47.36	2.00e-129	455.00
IUUC-Oru-084276	Oryza rufipogon	47.84	6.00e-131	460.00
IUUC-Osa-085849	Oryza sativa	47.84	6.00e-131	460.00
IUUC-Ola-086655	Oryzias latipes	84.87	0.00e+00	918.00
IUUC-Olu-087637	Ostreococcus lucimarinus	58.91	5.00e-119	421.00
IUUC-Oga-087934	Otolemur garnettii	75.24	0.00e+00	805.00
IUUC-Oar-090185	Ovis aries	75.44	0.00e+00	810.00
IUUC-Ptr-091198	Pan troglodytes	75.44	0.00e+00	803.00
IUUC-Pan-092622	Papio anubis	75.24	0.00e+00	801.00
IUUC-Psi-093320	Pelodiscus sinensis	76.94	0.00e+00	825.00
IUUC-Pma-094638	Petromyzon marinus	76.16	0.00e+00	828.00
IUUC-Pno-094826	Phaeosphaeria nodorum	49.08	3.00e-105	375.00
IUUC-Ppa-095576	Physcomitrella patens	61.83	2.00e-121	429.00
IUUC-Pfo-096894	Poecilia formosa	85.24	0.00e+00	906.00
IUUC-Pab-098020	Pongo abelii	75.44	0.00e+00	804.00
IUUC-Pop-099180	Populus trichocarpa	49.20	6.00e-126	444.00
IUUC-Pca-100909	Procavia capensis	70.00	4.00e-178	617.00
IUUC-Ppe-101346	Prunus persica	46.89	8.00e-126	443.00
IUUC-Pva-102167	Pteropus vampyrus	63.35	0.00e+00	645.00
IUUC-Pgr-103516	Puccinia graminis	49.89	1.00e-129	456.00
IUUC-Ptt-103738	Puccinia triticina	51.60	4.00e-130	457.00
IUUC-Pte-104352	Pyrenophora teres	60.29	2.00e-132	465.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	60.88	2.00e-133	468.00
IUUC-Rno-105291	Rattus norvegicus	75.83	0.00e+00	804.00
IUUC-Sce-106204	Saccharomyces cerevisiae	48.64	2.00e-100	359.00
IUUC-Sha-106943	Sarcophilus harrisii	75.39	0.00e+00	799.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	65.71	4.00e-128	451.00
IUUC-Spo-108049	Schizosaccharomyces pombe	55.88	6.00e-133	467.00
IUUC-Smo-109043	Selaginella moellendorffii	61.14	1.00e-125	442.00
IUUC-Sit-110431	Setaria italica	50.83	9.00e-132	463.00
IUUC-Sly-111391	Solanum lycopersicum	62.30	7.00e-119	420.00
IUUC-Stu-112364	Solanum tuberosum	56.25	1.00e-96	345.00
IUUC-Sar-113450	Sorex araneus	87.39	0.00e+00	656.00
IUUC-Sbi-113829	Sorghum bicolor	51.04	3.00e-133	468.00
IUUC-Sre-115153	Sporisorium reilianum	64.17	1.00e-119	423.00
IUUC-Ssc-116274	Sus scrofa	75.63	0.00e+00	807.00
IUUC-Tgu-117417	Taeniopygia guttata	75.33	0.00e+00	822.00
IUUC-Tsy-119480	Tarsius syrichta	75.34	0.00e+00	804.00
IUUC-Tni-119847	Tetraodon nigroviridis	96.63	0.00e+00	1013.00
IUUC-Tca-121287	Theobroma cacao	48.24	1.00e-129	456.00
IUUC-Tre-122010	Trichoderma reesei	66.67	2.00e-142	499.00
IUUC-Tvi-122475	Trichoderma virens	65.77	1.00e-141	496.00
IUUC-Tae-124397	Triticum aestivum	50.73	2.00e-133	469.00
IUUC-Tur-126116	Triticum urartu	43.11	2.00e-100	359.00
IUUC-Tme-126992	Tuber melanosporum	64.62	1.00e-136	479.00
IUUC-Tbe-127803	Tupaia belangeri	68.76	4.00e-172	597.00
IUUC-Ttr-128933	Tursiops truncatus	75.39	0.00e+00	805.00
IUUC-Uma-129447	Ustilago maydis	61.56	7.00e-116	410.00
IUUC-Vda-129780	Verticillium dahliae	64.04	3.00e-137	481.00
IUUC-Vpa-130557	Vicugna pacos	65.17	2.00e-74	273.00
IUUC-Vvi-130918	Vitis vinifera	46.82	1.00e-120	426.00
IUUC-Xtr-132409	Xenopus tropicalis	77.56	0.00e+00	816.00
IUUC-Xma-133420	Xiphophorus maculatus	84.80	0.00e+00	902.00
IUUC-Yli-134362	Yarrowia lipolytica	52.10	3.00e-122	431.00
IUUC-Zma-135804	Zea mays	49.28	1.00e-126	446.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence