iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036869

Ensembl Protein ID

ENSFALP00000006981.1

UniProt Accession

U3JW27; U3JW27_FICAL

Genbank Protein ID

ENSFALP00000006981

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020342

Gene Name

WDR48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000006692.1	ENSFALT00000007010.1	ENSFALP00000006981.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-33	111.3	231	268
UBD/Beta-Prp	2.30e-47	161.3	54	317
ULD/UDP/UFD/RAWUL	9.90e-24	83.4	591	696
ULD/UBL/SUMO	4.80e-62	206.4	582	689

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHtd v +l +  d t  +sGs Dgti++W+l +++++
   Q: 231  GHTDNVKALLLnRDgTQCLSGSSDGTIRLWSLGQQRCI 268
           8********88*888*****************999997 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkl...lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           + +++++  p  + l+t++rd+ i++w+v + k    ++s++ h++ v+++ +  +gk+l+++s+D t+kvw+  +g c++tl+ h+d+
   Q: 54   NGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQdpyIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDY 142
           556677888888999****************999999**************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           v +l++ ++++ ++s++ dr i +wd++t + l +         lsg+++++ ++++++ g ++vsGs+ +++r+Wd +t   l +l+g
   Q: 143  VKALAYAKDKELVASAGLDRQIFLWDVNTLTALTAsnntvttsSLSGNKDSIYSLAMNQMGTVIVSGSTEKVLRVWDPRTCAKLMKLKG 231
           *********************************9999****999**********************************99999999999 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            htd v+ l ++++g++++sgs dgt++lw+l +++c+ t++ h++ v+ +++ +  ++++sg+ D+ i++ dlr+ d+   +  ++
   Q: 232  -HTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEK 317
           .***********************************************************************999988766655555 PP

ULD/UDP/UFD/RAWUL

   S: 4    sLeplesnkakddsklkkkylrcsarltVkhlkkflaeklkl........sssy.....................evdllcedevLedn 63
            L+p++s++ak+   lkk++l++s++l+V++++++++ek+++        s                        +++llc+d+vL++n
   Q: 591  YLQPHSSSGAKT---LKKDRLSASDMLQVRKVMEHVYEKIINldnesqttS--SsnnekageqekeediavlaeeKIELLCQDQVLDPN 674
           69**********...*************************99988766653..045799999999************************ PP
   S: 64   etLeeikyifiwkkegpLvLqYr 86
           ++L+++ ++fiwk++g+L+L+Yr
   Q: 675  MDLRTV-KHFIWKSGGDLTLHYR 696
           ******.***************9 PP

ULD/UBL/SUMO

   S: 1    eskffkapvslkvagqdGsevlfklklsa....qlkklmeavYvkrinldensvrfv.fngqkireqetpeelevededkiellcq... 81
           ++kf+k+p++l++++++G+++l+k++lsa    q++k+me+vY+k+inld++s++++ +n++k +eqe++e+++v++e+kiellcq   
   Q: 582  MPKFNKIPFYLQPHSSSGAKTLKKDRLSAsdmlQVRKVMEHVYEKIINLDNESQTTSsSNNEKAGEQEKEEDIAVLAEEKIELLCQdqv 670
           8********************************************************9****************************777 PP
   S: 82   ...............ksGG 85
                          ksGG
   Q: 671  ldpnmdlrtvkhfiwKSGG 689
           7777777777777777776 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MQDGGASPAE HGGAAESAEV PVASSRQHLL KETRGTGSQV SYVIRDEVEK YNRNGVNALQ 60
LDPALNRLFT AGRDSIIRIW SVNQHKQDPY IASMEHHTDW VNDIVLCCNG KTLISASSDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTAACATA AGCCTTTCGC CGCCACTCGA GACGATGCAA AGCGGGACGA ACACACCGCA 60
GGAGCATCAA GACGTGGACG GGGACAAAGC AAGAGCGGCA GGACAGGGAA GGGGAAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR021772--DUF3337
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF11816--DUF3337
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0000724--P:double-strand break repair via homologous recombination
GO:0048568--P:embryonic organ development
GO:0048872--P:homeostasis of number of cells
GO:0035264--P:multicellular organism growth
GO:0050679--P:positive regulation of epithelial cell proliferation
GO:0016579--P:protein deubiquitination
GO:1902525--P:regulation of protein monoubiquitination
GO:0072520--P:seminiferous tubule development
GO:0007338--P:single fertilization
GO:0048705--P:skeletal system morphogenesis
GO:0043588--P:skin development
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001160	Aegilops tauschii	40.00	5.00e-96	345.00
IUUC-Aml-001533	Ailuropoda melanoleuca	98.19	0.00e+00	1234.00
IUUC-Atr-003009	Amborella trichopoda	33.95	2.00e-110	392.00
IUUC-Apl-003709	Anas platyrhynchos	100.00	0.00e+00	674.00
IUUC-Aca-004875	Anolis carolinensis	99.09	0.00e+00	1276.00
IUUC-Aly-005464	Arabidopsis lyrata	40.73	7.00e-94	338.00
IUUC-Ath-006969	Arabidopsis thaliana	39.80	5.00e-89	322.00
IUUC-Acl-008203	Aspergillus clavatus	35.69	1.00e-47	185.00
IUUC-Afl-008571	Aspergillus flavus	35.33	2.00e-46	181.00
IUUC-Afu-009072	Aspergillus fumigatus	35.33	6.00e-45	176.00
IUUC-Ani-009413	Aspergillus nidulans	36.41	5.00e-48	186.00
IUUC-Ang-009571	Aspergillus niger	35.33	2.00e-45	177.00
IUUC-Aor-010064	Aspergillus oryzae	35.63	7.00e-47	182.00
IUUC-Ate-010463	Aspergillus terreus	35.03	3.00e-46	180.00
IUUC-Ame-010875	Astyanax mexicanus	94.40	0.00e+00	1092.00
IUUC-Bgr-012288	Blumeria graminis	33.83	8.00e-41	162.00
IUUC-Bta-013379	Bos taurus	98.04	0.00e+00	1232.00
IUUC-Bci-013859	Botrytis cinerea	32.83	7.00e-41	162.00
IUUC-Bdi-014645	Brachypodium distachyon	34.93	6.00e-111	394.00
IUUC-Bol-016450	Brassica oleracea	34.87	4.00e-101	362.00
IUUC-Bra-017237	Brassica rapa	34.61	8.00e-103	367.00
IUUC-Cel-018656	Caenorhabditis elegans	44.62	1.00e-156	546.00
IUUC-Cja-018804	Callithrix jacchus	98.04	0.00e+00	1229.00
IUUC-Cfa-020076	Canis familiaris	98.19	0.00e+00	1234.00
IUUC-Cpo-021721	Cavia porcellus	96.53	0.00e+00	1208.00
IUUC-Cre-022779	Chlamydomonas reinhardtii	31.28	1.00e-40	162.00
IUUC-Csa-023188	Chlorocebus sabaeus	98.19	0.00e+00	1234.00
IUUC-Cho-024932	Choloepus hoffmanni	96.98	0.00e+00	1238.00
IUUC-Cin-025591	Ciona intestinalis	57.54	0.00e+00	714.00
IUUC-Cgl-026540	Colletotrichum gloeosporioides	27.24	3.00e-20	94.00
IUUC-Cne-026819	Cryptococcus neoformans	35.53	8.00e-35	142.00
IUUC-Cme-027188	Cyanidioschyzon merolae	31.59	2.00e-71	263.00
IUUC-Dre-027926	Danio rerio	93.05	0.00e+00	1245.00
IUUC-Dno-029960	Dasypus novemcinctus	97.58	0.00e+00	1224.00
IUUC-Dor-030933	Dipodomys ordii	93.77	0.00e+00	707.00
IUUC-Dse-031532	Dothistroma septosporum	36.00	1.00e-45	178.00
IUUC-Dme-032168	Drosophila melanogaster	56.95	0.00e+00	679.00
IUUC-Ete-033107	Echinops telfairi	95.61	0.00e+00	1188.00
IUUC-Eca-034028	Equus caballus	98.34	0.00e+00	1235.00
IUUC-Eeu-034894	Erinaceus europaeus	95.26	0.00e+00	841.00
IUUC-Fca-035619	Felis catus	98.11	0.00e+00	915.00
IUUC-Fox-037907	Fusarium oxysporum	32.47	2.00e-40	161.00
IUUC-Fso-038101	Fusarium solani	32.76	7.00e-40	159.00
IUUC-Gmo-038627	Gadus morhua	95.47	0.00e+00	1264.00
IUUC-Ggr-039995	Gaeumannomyces graminis	30.83	1.00e-41	165.00
IUUC-Gga-040555	Gallus gallus	99.55	0.00e+00	1280.00
IUUC-Gac-042497	Gasterosteus aculeatus	95.32	0.00e+00	1236.00
IUUC-Gma-043089	Glycine max	34.70	5.00e-109	388.00
IUUC-Ggo-045561	Gorilla gorilla	98.19	0.00e+00	1234.00
IUUC-Hsa-045710	Homo sapiens	98.19	0.00e+00	1234.00
IUUC-Hvu-047730	Hordeum vulgare	35.28	2.00e-84	306.00
IUUC-Itr-049030	Ictidomys tridecemlineatus	97.89	0.00e+00	891.00
IUUC-Kpa-049237	Komagataella pastoris	30.58	6.00e-30	125.00
IUUC-Lch-049507	Latimeria chalumnae	97.58	0.00e+00	1242.00
IUUC-Lpe-051608	Leersia perrieri	34.69	8.00e-109	387.00
IUUC-Loc-052373	Lepisosteus oculatus	93.98	0.00e+00	1221.00
IUUC-Lma-053025	Leptosphaeria maculans	35.61	1.00e-48	188.00
IUUC-Laf-053706	Loxodonta africana	97.58	0.00e+00	1227.00
IUUC-Mcc-055046	Macaca mulatta	98.19	0.00e+00	1234.00
IUUC-Meu-056840	Macropus eugenii	81.02	1.00e-150	526.00
IUUC-Mor-057284	Magnaporthe oryzae	32.63	1.00e-42	168.00
IUUC-Mpo-057418	Magnaporthe poae	30.28	7.00e-40	159.00
IUUC-Mtr-058571	Medicago truncatula	34.79	6.00e-109	388.00
IUUC-Mla-059101	Melampsora laricipopulina	44.61	1.00e-45	179.00
IUUC-Mga-059297	Meleagris gallopavo	99.55	0.00e+00	1280.00
IUUC-Mvi-060419	Microbotryum violaceum	39.74	2.00e-38	154.00
IUUC-Mmr-061196	Microcebus murinus	91.71	0.00e+00	1141.00
IUUC-Mdo-062762	Monodelphis domestica	94.19	0.00e+00	1249.00
IUUC-Mmu-063915	Mus musculus	96.98	0.00e+00	1251.00
IUUC-Mac-065434	Musa acuminata	34.47	1.00e-105	377.00
IUUC-Mpu-065999	Mustela putorius furo	97.82	0.00e+00	809.00
IUUC-Mlu-068226	Myotis lucifugus	97.89	0.00e+00	1229.00
IUUC-Nfi-068416	Neosartorya fischeri	34.54	6.00e-47	182.00
IUUC-Ncr-068825	Neurospora crassa	31.30	9.00e-39	155.00
IUUC-Nle-069416	Nomascus leucogenys	98.19	0.00e+00	1234.00
IUUC-Opr-070515	Ochotona princeps	93.66	0.00e+00	1157.00
IUUC-Ont-072052	Oreochromis niloticus	92.79	0.00e+00	1176.00
IUUC-Oan-073636	Ornithorhynchus anatinus	95.02	0.00e+00	1255.00
IUUC-Ocu-074799	Oryctolagus cuniculus	98.04	0.00e+00	1231.00
IUUC-Oba-075146	Oryza barthii	35.00	2.00e-109	389.00
IUUC-Obr-076699	Oryza brachyantha	34.85	7.00e-110	391.00
IUUC-Ogl-077883	Oryza glaberrima	33.27	9.00e-67	247.00
IUUC-Ogu-078114	Oryza glumaepatula	34.99	6.00e-109	387.00
IUUC-Oin-079575	Oryza indica	35.03	4.00e-112	398.00
IUUC-Olo-080531	Oryza longistaminata	32.55	2.00e-98	353.00
IUUC-Ome-081368	Oryza meridionalis	40.65	1.00e-96	347.00
IUUC-Oni-082457	Oryza nivara	35.00	2.00e-109	390.00
IUUC-Opu-084050	Oryza punctata	34.86	3.00e-108	385.00
IUUC-Oru-084330	Oryza rufipogon	35.00	3.00e-109	389.00
IUUC-Osa-085408	Oryza sativa	35.03	4.00e-112	398.00
IUUC-Ola-087546	Oryzias latipes	94.77	0.00e+00	1238.00
IUUC-Olu-087710	Ostreococcus lucimarinus	31.56	1.00e-79	290.00
IUUC-Oga-087998	Otolemur garnettii	98.19	0.00e+00	1234.00
IUUC-Oar-090303	Ovis aries	98.04	0.00e+00	1232.00
IUUC-Ptr-090588	Pan troglodytes	98.19	0.00e+00	1234.00
IUUC-Pan-092722	Papio anubis	98.19	0.00e+00	1234.00
IUUC-Psi-093911	Pelodiscus sinensis	98.65	0.00e+00	1272.00
IUUC-Pma-094580	Petromyzon marinus	88.22	0.00e+00	1162.00
IUUC-Pno-095085	Phaeosphaeria nodorum	34.71	2.00e-43	170.00
IUUC-Ppa-095594	Physcomitrella patens	36.02	4.00e-113	402.00
IUUC-Pfo-096994	Poecilia formosa	94.90	0.00e+00	1233.00
IUUC-Pab-097586	Pongo abelii	98.04	0.00e+00	1232.00
IUUC-Pop-099740	Populus trichocarpa	34.89	3.00e-102	365.00
IUUC-Pca-100458	Procavia capensis	97.60	2.00e-106	379.00
IUUC-Ppe-102060	Prunus persica	34.30	1.00e-106	380.00
IUUC-Pva-102698	Pteropus vampyrus	93.50	0.00e+00	1215.00
IUUC-Pgr-103649	Puccinia graminis	39.08	4.00e-48	186.00
IUUC-Ptt-103910	Puccinia triticina	39.04	1.00e-52	201.00
IUUC-Pte-104181	Pyrenophora teres	36.14	2.00e-48	187.00
IUUC-Pyt-104439	Pyrenophora triticirepentis	35.84	5.00e-48	186.00
IUUC-Rno-104978	Rattus norvegicus	97.13	0.00e+00	1250.00
IUUC-Sha-107079	Sarcophilus harrisii	97.78	0.00e+00	1202.00
IUUC-Sja-107716	Schizosaccharomyces japonicus	34.23	3.00e-46	180.00
IUUC-Spo-108325	Schizosaccharomyces pombe	30.94	1.00e-51	198.00
IUUC-Ssl-108542	Sclerotinia sclerotiorum	32.54	4.00e-38	153.00
IUUC-Smo-109427	Selaginella moellendorffii	34.93	3.00e-109	389.00
IUUC-Sit-110755	Setaria italica	36.59	7.00e-114	404.00
IUUC-Sly-111099	Solanum lycopersicum	35.16	2.00e-98	353.00
IUUC-Sar-113408	Sorex araneus	98.14	0.00e+00	734.00
IUUC-Sbi-113789	Sorghum bicolor	35.17	3.00e-110	392.00
IUUC-Sre-114998	Sporisorium reilianum	40.92	4.00e-53	203.00
IUUC-Ssc-115434	Sus scrofa	98.19	0.00e+00	1234.00
IUUC-Tgu-116517	Taeniopygia guttata	99.85	0.00e+00	1285.00
IUUC-Tru-118174	Takifugu rubripes	95.34	0.00e+00	1241.00
IUUC-Tsy-118935	Tarsius syrichta	97.89	0.00e+00	1259.00
IUUC-Tni-119744	Tetraodon nigroviridis	95.77	0.00e+00	1209.00
IUUC-Tca-121360	Theobroma cacao	34.17	3.00e-110	392.00
IUUC-Tre-122198	Trichoderma reesei	32.27	2.00e-42	167.00
IUUC-Tvi-122389	Trichoderma virens	31.44	3.00e-42	167.00
IUUC-Tae-125576	Triticum aestivum	35.17	9.00e-112	397.00
IUUC-Tur-126699	Triticum urartu	34.56	9.00e-109	387.00
IUUC-Tme-126932	Tuber melanosporum	31.30	1.00e-54	208.00
IUUC-Tbe-127267	Tupaia belangeri	83.44	0.00e+00	728.00
IUUC-Ttr-129153	Tursiops truncatus	97.58	0.00e+00	1263.00
IUUC-Uma-129604	Ustilago maydis	38.20	1.00e-50	195.00
IUUC-Vda-129925	Verticillium dahliae	34.51	4.00e-45	176.00
IUUC-Vpa-130553	Vicugna pacos	97.26	0.00e+00	942.00
IUUC-Vvi-130995	Vitis vinifera	34.22	8.00e-106	377.00
IUUC-Xtr-132346	Xenopus tropicalis	95.02	0.00e+00	1208.00
IUUC-Xma-134266	Xiphophorus maculatus	92.91	0.00e+00	671.00
IUUC-Yli-134451	Yarrowia lipolytica	30.89	7.00e-35	142.00
IUUC-Zma-135647	Zea mays	35.29	7.00e-112	397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence